#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8CHV6 uniprotkb:Q9D7W5 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985298(identity)|uniprotkb:Q9D7W5(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9DA08 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990274|intact:MINT-4127866|uniprotkb:Q8R0I6|ensembl:ENSMUSP00000032956 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:sgf29_mouse(display_long)|uniprotkb:Sgf29(gene name)|psi-mi:Sgf29(display_short)|uniprotkb:Ccdc101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:XP_017167854.1|refseq:NP_083615.3|ensembl:ENSMUSG00000030714(gene)|ensembl:ENSMUST00000032956(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q9DA08|mint:MINT-7985286(identity)|uniprotkb:Q9DA08(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint|function:"Involved in transcriptional regulation, probably through association with histone acetyltransferase (HAT) complexes like the TFTC-HAT or STAGA complexes. May be involved in c-Myc-mediated oncogenic transformation" comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:1DKiknY6Ru9KBYHcjtmI+cCZk2A10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8CHV6 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985283(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8CID0 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990326|intact:UNK-5517679|uniprotkb:A2ANA8|ensembl:ENSMUSP00000028911 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:csr2b_mouse(display_long)|uniprotkb:Kat14(gene name)|psi-mi:Kat14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:Csrp2bp(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_852082.2|ensembl:ENSMUSG00000027425(gene)|ensembl:ENSMUST00000028911(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0016573"(histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:MINT-7985361(identity)|uniprotkb:Q8CID0(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:bcf5vmJJQM4kTolB7xnf9nyCqOk10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q91WV0 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990301|uniprotkb:Q3UT14|intact:MINT-4610141|ensembl:ENSMUSP00000031190 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:nc2b_mouse(display_long)|uniprotkb:Dr1(gene name)|psi-mi:Dr1(display_short)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080382.2|ensembl:ENSMUSG00000029265(gene)|ensembl:ENSMUST00000031190(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:MINT-7985295(identity)|uniprotkb:Q91WV0(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" function:The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own|comment:mint comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:IOvFm/PDjH0LRYpn8XRb1V3rZr010090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q99LQ1 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-688604|uniprotkb:Q3TBM3|ensembl:ENSMUSP00000021416 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:mbip1_mouse(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:Mbip(gene name)|psi-mi:Mbip(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_663417.1|ensembl:ENSMUSG00000021028(gene)|ensembl:ENSMUST00000021416(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q99LQ1|mint:MINT-7985355(identity)|uniprotkb:Q99LQ1(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:KtWoLiw2udaTSOzc3EHifvyF45M10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:A2AGH6 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5744969|uniprotkb:A2AGH7|uniprotkb:O88542|uniprotkb:Q571H3|uniprotkb:Q6PGB4|uniprotkb:Q6PGD8|ensembl:ENSMUSP00000085260 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med12_mouse(display_long)|uniprotkb:Med12(gene name)|psi-mi:Med12(display_short)|uniprotkb:Kiaa0192(gene name synonym)|uniprotkb:Mopa(gene name synonym)|uniprotkb:Tnrc11(gene name synonym)|uniprotkb:Trap230(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_067496.2|go:"GO:0048568"(embryonic organ development)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:A2AGH6|reactome:R-MMU-212436|ensembl:ENSMUSG00000079487(gene)|ensembl:ENSMUST00000087948(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|dip:DIP-59233N|mint:MINT-7985349(identity)|uniprotkb:A2AGH6(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:9l10cOqNn+PIwL7gQq/WsgiZnLE10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:P08775 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N|mint:MINT-7985292(identity)|uniprotkb:P08775(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9CQ39 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N|mint:MINT-7985325(identity)|uniprotkb:Q9CQ39(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q3TUF7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5738806|uniprotkb:Q6PGF8|uniprotkb:Q80TI2|uniprotkb:Q8CG86|ensembl:ENSMUSP00000111222 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:yets2_mouse(display_long)|uniprotkb:Yeats2(gene name)|psi-mi:Yeats2(display_short)|uniprotkb:Kiaa1197(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001028409.2|refseq:NP_001139402.1|refseq:XP_006521965.1|ensembl:ENSMUSG00000041215(gene)|ensembl:ENSMUST00000115560(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:MINT-7985274(identity)|uniprotkb:Q3TUF7(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:xiOuCMewv3+xE2m0DSpmdbaK3DY10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9DB40 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745248|uniprotkb:A2AJV2|uniprotkb:Q78JI3|uniprotkb:Q9D707|ensembl:ENSMUSP00000028139 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med27_mouse(display_long)|uniprotkb:Med27(gene name)|psi-mi:Med27(display_short)|uniprotkb:Crsp8(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Mediator complex subunit 27(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_083891.1|refseq:NP_081172.2|refseq:NP_001277419.1|ensembl:ENSMUSG00000026799(gene)|ensembl:ENSMUST00000028139(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q9DB40|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985313(identity)|uniprotkb:Q9DB40(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:3qxK1h1BWs2YxdQZkqUWn3G2vDE10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q6PGF3 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-6260816|uniprotkb:E9QM81 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med16_mouse(display_long)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thrap5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:Q6PGF3|dip:DIP-48408N|mint:MINT-7985337(identity)|uniprotkb:Q6PGF3(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:7RYpXMMTPBtLxPGifdlY+MdwlEM10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9JHD2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985358(identity)|uniprotkb:Q9JHD2(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:P61965 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-1247084|uniprotkb:Q91VA5|uniprotkb:Q922C9|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|ensembl:ENSMUSP00000109585 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:wdr5_mouse(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)|uniprotkb:Big(gene name synonym)|uniprotkb:Big3(gene name synonym)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WD repeat-containing protein BIG-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_543124.1|refseq:XP_006497735.1|dip:DIP-38618N|ensembl:ENSMUSG00000026917(gene)|ensembl:ENSMUST00000113952(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61965|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-8936459|reactome:R-MMU-8951664|mint:MINT-7985277(identity)|uniprotkb:P61965(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8CFI7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2549877|ensembl:ENSMUSP00000031167 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N|mint:MINT-7985289(identity)|uniprotkb:Q8CFI7(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q920D3 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-309215|uniprotkb:Q3U4G7|uniprotkb:Q9CQF2|ensembl:ENSMUSP00000115882 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med28_mouse(display_long)|uniprotkb:Med28(gene name)|psi-mi:Med28(display_short)|uniprotkb:Fksg20(orf name)|uniprotkb:Mediator complex subunit 28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080171.1|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q920D3|rcsb pdb:6W1S|ensembl:ENSMUSG00000015804(gene)|ensembl:ENSMUST00000156481(transcript)|mint:MINT-7985310(identity)|uniprotkb:Q920D3(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U69QDqUxcl7UWjo7qkiZKN5wwCg10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q99K74 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745029|uniprotkb:A3KFP0|uniprotkb:Q8R004|uniprotkb:Q9D277|uniprotkb:Q9WVF1|ensembl:ENSMUSP00000017354 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med24_mouse(display_long)|uniprotkb:Med24(gene name)|psi-mi:Med24(display_short)|uniprotkb:D11Ertd307e(gene name synonym)|uniprotkb:Thrap4(gene name synonym)|uniprotkb:Trap100(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_035999.2|ensembl:ENSMUSG00000017210(gene)|ensembl:ENSMUST00000017354(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR021429|rcsb pdb:6W1S|reactome:R-MMU-212436|refseq:XP_006533368.1|mint:MINT-7985319(identity)|uniprotkb:Q99K74(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:GSdhLyTQrKwK1ya/qhMSzAdmFBg10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q5SWW4 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745218|uniprotkb:Q3V3P6|uniprotkb:Q6ZQ90|ensembl:ENSMUSP00000044268 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med13_mouse(display_long)|uniprotkb:Med13(gene name)|psi-mi:Med13(display_short)|uniprotkb:Kiaa0593(gene name synonym)|uniprotkb:Thrap1(gene name synonym)|uniprotkb:Trap240(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001074400.1|dip:DIP-61082N|ensembl:ENSMUSG00000034297(gene)|ensembl:ENSMUST00000043624(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR009401(TRAP240)|interpro:IPR041285|reactome:R-MMU-212436|mint:MINT-7985346(identity)|uniprotkb:Q5SWW4(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:aRRZBYOAGdDeO32VOWKyVHJGZ9w10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q7TN02 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436|mint:MINT-7985316(identity)|uniprotkb:Q7TN02(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9CXU1 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985307(identity)|uniprotkb:Q9CXU1(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8VCD5 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N|mint:MINT-7985334(identity)|uniprotkb:Q8VCD5(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:RphTDePi36YqZFcRmkcobUnPd7I10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q80YQ2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745001|uniprotkb:Q6ZPV7|uniprotkb:Q8CEC3|uniprotkb:Q8K587|uniprotkb:Q9CXY8 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med23_mouse(display_long)|uniprotkb:Med23(gene name)|psi-mi:Med23(display_short)|uniprotkb:Crsp3(gene name synonym)|uniprotkb:Kiaa1216(gene name synonym)|uniprotkb:Sur2(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001159888.1|refseq:NP_081623.3|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:2000409"(positive regulation of T cell extravasation)|interpro:IPR021629|rcsb pdb:6W1S|dip:DIP-59234N|reactome:R-MMU-212436|mint:MINT-7985322(identity)|uniprotkb:Q80YQ2(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:unJwhtOAP16TniaelImM6E3JM8o10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9CZ82 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745371|ensembl:ENSMUSP00000099627 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med18_mouse(display_long)|uniprotkb:Med18(gene name)|psi-mi:Med18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080315.1|ensembl:ENSMUSG00000066042(gene)|ensembl:ENSMUST00000102567(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:6W1S|mint:MINT-7985331(identity)|uniprotkb:Q9CZ82(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:kT/sqHFq4fNAZNniipeC4tP0d2s10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8R0L9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943209|ensembl:ENSMUSP00000032410|uniprotkb:Q8CIH4|uniprotkb:Q8K289|uniprotkb:Q8R5E3|uniprotkb:Q9CTJ0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:tada3_mouse(display_long)|uniprotkb:Tada3(gene name)|psi-mi:Tada3(display_short)|uniprotkb:Ada3(gene name synonym)|uniprotkb:Tada3l(gene name synonym)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000048930(gene)|ensembl:ENSMUST00000032410(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:Q8R0L9|reactome:R-MMU-5689880|refseq:NP_598693.1|mint:MINT-7985280(identity)|uniprotkb:Q8R0L9(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:0IoyeTJIBrH6bDyjYJsKozMPSC010090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q6KAQ7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5737882|uniprotkb:Q3TMK6|uniprotkb:Q3V189|ensembl:ENSMUSP00000101706|ensembl:ENSMUSP00000101707 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:zzz3_mouse(display_long)|uniprotkb:Zzz3(gene name)|psi-mi:Zzz3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001074224.1|refseq:XP_006500911.1|refseq:XP_006500913.1|refseq:XP_006500914.1|refseq:XP_006500919.1|refseq:XP_006500920.1|refseq:NP_001333584.1|refseq:XP_017174912.1|ensembl:ENSMUSG00000039068(gene)|ensembl:ENSMUST00000106100(transcript)|ensembl:ENSMUST00000106101(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|mint:MINT-7985271(identity)|uniprotkb:Q6KAQ7(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:ed0sQkhcg/sF4D2uu6Fnw+WzCzA10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9CQA5 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745428|uniprotkb:Q3UL96|uniprotkb:Q8BVG6|ensembl:ENSMUSP00000022705 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med4_mouse(display_long)|uniprotkb:Med4(gene name)|psi-mi:Med4(display_short)|uniprotkb:Vdrip(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080395.1|ensembl:ENSMUSG00000022109(gene)|ensembl:ENSMUST00000022705(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9CQA5|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985304(identity)|uniprotkb:Q9CQA5(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:mxprXZb8/S6/jNJVDSvApugwGiQ10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q925J9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985352(identity)|uniprotkb:Q925J9(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:A2ABV5 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5744924|uniprotkb:Q3TQU3|uniprotkb:Q6P1H5|uniprotkb:Q9R0T1|uniprotkb:Q9WTN9|ensembl:ENSMUSP00000094239 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med14_mouse(display_long)|uniprotkb:Med14(gene name)|psi-mi:Med14(display_short)|uniprotkb:Crsp2(gene name synonym)|uniprotkb:Gm641(gene name synonym)|uniprotkb:Trap170(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001041673.1|refseq:NP_036135.3|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:6W1S|reactome:R-MMU-212436|ensembl:ENSMUSG00000064127(gene)|ensembl:ENSMUST00000096495(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:MINT-7985343(identity)|uniprotkb:A2ABV5(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:zYS7ClZGBQS0njhhSZ9xew2FSLI10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q924H2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-6260935|ensembl:ENSMUSP00000012259|uniprotkb:G3X8S4 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med15_mouse(display_long)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Pcqap(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:Med15(gene name)|psi-mi:Med15(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000012114(gene)|ensembl:ENSMUST00000012259(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|interpro:IPR019087|interpro:IPR036529|mint:Q924H2|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-59237N|refseq:NP_291087.2|mint:MINT-7985340(identity)|uniprotkb:Q924H2(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:mZasSGGG3iCf4B+EFvrHwfeRm0I10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9R0X0 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985328(identity)|uniprotkb:Q9R0X0(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q921D4 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745383|uniprotkb:Q3TAK5|uniprotkb:Q8BTP9|ensembl:ENSMUSP00000125156 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med6_mouse(display_long)|uniprotkb:Med6(gene name)|psi-mi:Med6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990294|mint:MINT-7985266|imex:IM-15001-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985267(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_081489.2|refseq:NP_001334313.1|refseq:NP_001334315.1|dip:DIP-60703N|ensembl:ENSMUSG00000002679(gene)|ensembl:ENSMUST00000161211(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985301(identity)|uniprotkb:Q921D4(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:T1 F1B SF1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:zmKsMA5JwAtTd32b4TAbAnwHmxs10090 intact-crc:86BA1672D4D3BEA9|rigid:ZLh1r3c5CibcLrEHjHdiMOaiCZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q91WV0 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990301|uniprotkb:Q3UT14|intact:MINT-4610141|ensembl:ENSMUSP00000031190 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:nc2b_mouse(display_long)|uniprotkb:Dr1(gene name)|psi-mi:Dr1(display_short)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_080382.2|ensembl:ENSMUSG00000029265(gene)|ensembl:ENSMUST00000031190(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:MINT-7985389(identity)|uniprotkb:Q91WV0(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" function:The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own|comment:mint figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:IOvFm/PDjH0LRYpn8XRb1V3rZr010090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9DA08 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990274|intact:MINT-4127866|uniprotkb:Q8R0I6|ensembl:ENSMUSP00000032956 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:sgf29_mouse(display_long)|uniprotkb:Sgf29(gene name)|psi-mi:Sgf29(display_short)|uniprotkb:Ccdc101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:XP_017167854.1|refseq:NP_083615.3|ensembl:ENSMUSG00000030714(gene)|ensembl:ENSMUST00000032956(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q9DA08|mint:MINT-7985383(identity)|uniprotkb:Q9DA08(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint|function:"Involved in transcriptional regulation, probably through association with histone acetyltransferase (HAT) complexes like the TFTC-HAT or STAGA complexes. May be involved in c-Myc-mediated oncogenic transformation" figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:1DKiknY6Ru9KBYHcjtmI+cCZk2A10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8CHV6 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985380(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8CID0 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7990326|intact:UNK-5517679|uniprotkb:A2ANA8|ensembl:ENSMUSP00000028911 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:csr2b_mouse(display_long)|uniprotkb:Kat14(gene name)|psi-mi:Kat14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:Csrp2bp(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_852082.2|ensembl:ENSMUSG00000027425(gene)|ensembl:ENSMUST00000028911(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0016573"(histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:MINT-7985395(identity)|uniprotkb:Q8CID0(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:bcf5vmJJQM4kTolB7xnf9nyCqOk10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:P61965 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-1247084|uniprotkb:Q91VA5|uniprotkb:Q922C9|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|ensembl:ENSMUSP00000109585 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:wdr5_mouse(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)|uniprotkb:Big(gene name synonym)|uniprotkb:Big3(gene name synonym)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WD repeat-containing protein BIG-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_543124.1|refseq:XP_006497735.1|dip:DIP-38618N|ensembl:ENSMUSG00000026917(gene)|ensembl:ENSMUST00000113952(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61965|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-8936459|reactome:R-MMU-8951664|mint:MINT-7985374(identity)|uniprotkb:P61965(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q6KAQ7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5737882|uniprotkb:Q3TMK6|uniprotkb:Q3V189|ensembl:ENSMUSP00000101706|ensembl:ENSMUSP00000101707 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:zzz3_mouse(display_long)|uniprotkb:Zzz3(gene name)|psi-mi:Zzz3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001074224.1|refseq:XP_006500911.1|refseq:XP_006500913.1|refseq:XP_006500914.1|refseq:XP_006500919.1|refseq:XP_006500920.1|refseq:NP_001333584.1|refseq:XP_017174912.1|ensembl:ENSMUSG00000039068(gene)|ensembl:ENSMUST00000106100(transcript)|ensembl:ENSMUST00000106101(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|mint:MINT-7985368(identity)|uniprotkb:Q6KAQ7(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:ed0sQkhcg/sF4D2uu6Fnw+WzCzA10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q99LQ1 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-688604|uniprotkb:Q3TBM3|ensembl:ENSMUSP00000021416 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:mbip1_mouse(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:Mbip(gene name)|psi-mi:Mbip(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_663417.1|ensembl:ENSMUSG00000021028(gene)|ensembl:ENSMUST00000021416(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q99LQ1|mint:MINT-7985392(identity)|uniprotkb:Q99LQ1(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:KtWoLiw2udaTSOzc3EHifvyF45M10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q3TUF7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5738806|uniprotkb:Q6PGF8|uniprotkb:Q80TI2|uniprotkb:Q8CG86|ensembl:ENSMUSP00000111222 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:yets2_mouse(display_long)|uniprotkb:Yeats2(gene name)|psi-mi:Yeats2(display_short)|uniprotkb:Kiaa1197(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_001028409.2|refseq:NP_001139402.1|refseq:XP_006521965.1|ensembl:ENSMUSG00000041215(gene)|ensembl:ENSMUST00000115560(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:MINT-7985371(identity)|uniprotkb:Q3TUF7(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:xiOuCMewv3+xE2m0DSpmdbaK3DY10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q8R0L9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943209|ensembl:ENSMUSP00000032410|uniprotkb:Q8CIH4|uniprotkb:Q8K289|uniprotkb:Q8R5E3|uniprotkb:Q9CTJ0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:tada3_mouse(display_long)|uniprotkb:Tada3(gene name)|psi-mi:Tada3(display_short)|uniprotkb:Ada3(gene name synonym)|uniprotkb:Tada3l(gene name synonym)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) ensembl:ENSMUSG00000048930(gene)|ensembl:ENSMUST00000032410(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:Q8R0L9|reactome:R-MMU-5689880|refseq:NP_598693.1|mint:MINT-7985377(identity)|uniprotkb:Q8R0L9(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:0IoyeTJIBrH6bDyjYJsKozMPSC010090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9JHD1 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2325611|uniprotkb:Q3U142|uniprotkb:Q640M9|ensembl:ENSMUSP00000000724 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2b_mouse(display_long)|uniprotkb:Pcaf(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:Kat2b(gene name)|psi-mi:Kat2b(display_short)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990569|mint:MINT-7985364|imex:IM-15001-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985365(identity)|uniprotkb:Q8CHV6(original identifier) refseq:NP_064389.2|dip:DIP-29281N|ensembl:ENSMUSG00000000708(gene)|ensembl:ENSMUST00000000724(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042311"(vasodilation)|go:"GO:0042641"(actomyosin)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:2000233"(negative regulation of rRNA processing)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD1|rcsb pdb:5ML0|reactome:R-MMU-2032785|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-5689901|reactome:R-MMU-8936459|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-9617629|mint:MINT-7985386(identity)|uniprotkb:Q9JHD1(original identifier) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" caution:This sequence has been withdrawn from Uniprot. figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:xnaxRvvz5/uqJD0Zt6tnXNQJ43g10090 intact-crc:DC88B82841D7721E|rigid:WKSPtxiFLc7yKV9pZG1hdbvCEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8CHV6 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985438(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8R4I1 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990748|uniprotkb:E9QPX9|intact:UNK-5525593|uniprotkb:Q8BL17|ensembl:ENSMUSP00000022257|ensembl:ENSMUSP00000152934 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:atx7_mouse(display_long)|uniprotkb:Atxn7(gene name)|psi-mi:Atxn7(display_short)|uniprotkb:Sca7(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 7 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) dip:DIP-29176N|refseq:NP_631973.3|ensembl:ENSMUSG00000021738(gene)|ensembl:ENSMUST00000022257(transcript)|ensembl:ENSMUST00000223880(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR013243(SCA7)|interpro:IPR030706|reactome:R-MMU-5689880|mint:MINT-7985417(identity)|uniprotkb:Q8R4I1(original identifier) go:"GO:0005634"(nucleus) - function:Involved in neurodegeneration. Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation|comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:QxhOtTIxpgF6pvAfVwWQ//A6SY810090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q80YT5 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990667|intact:UNK-5501527|ensembl:ENSMUSP00000042572 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:spt20_mouse(display_long)|uniprotkb:Spata20(gene name)|psi-mi:Spata20(display_short)|uniprotkb:Tisp78(gene name synonym)|uniprotkb:Transcript increased in spermiogenesis 78 protein(gene name synonym)|uniprotkb:Sperm-specific protein 411(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_659076.2|ensembl:ENSMUSG00000020867(gene)|ensembl:ENSMUST00000041705(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR004879(Protein of unknown function DUF255)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR024705|interpro:IPR036249|mint:MINT-7985402(identity)|uniprotkb:Q80YT5(original identifier) go:"GO:0005634"(nucleus) - function:May play a role in fertility regulation|comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:O8BITvutVTFM6QfqLgDzUGs3FTk10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:A2AWT3 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990620|intact:MINT-7984980|uniprotkb:Q8C1T7|uniprotkb:A2AWT2|uniprotkb:A2AWT4|ensembl:ENSMUSP00000072967|ensembl:ENSMUSP00000102752 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:at7l3_mouse(display_long)|uniprotkb:Atxn7l3(gene name)|psi-mi:Atxn7l3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_001092306.1|refseq:NP_001092307.1|ensembl:ENSMUSG00000059995(gene)|ensembl:ENSMUST00000073234(transcript)|ensembl:ENSMUST00000107134(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:MINT-7985432(identity)|uniprotkb:A2AWT3(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:hpFMkpasLzY9LiiFbjAID2EjvMw10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8VE65 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990784|intact:MINT-4136826|uniprotkb:Q9D8Q0|uniprotkb:Q3V0S7|uniprotkb:Q9CZ11|ensembl:ENSMUSP00000030731 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:taf12_mouse(display_long)|uniprotkb:Taf12(gene name)|psi-mi:Taf12(display_short)|uniprotkb:Transcription initiation factor TFIID 20 kDa subunits(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:XP_017175839.1|dip:DIP-29178N|refseq:NP_079855.2|refseq:XP_006539172.1|refseq:XP_006539173.1|refseq:XP_006539170.2|ensembl:ENSMUSG00000028899(gene)|ensembl:ENSMUST00000030731(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|mint:Q8VE65|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|mint:MINT-7985420(identity)|uniprotkb:Q8VE65(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription" comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:5G+IyLHK+TK5l4RTTFIPh8B650g10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:B7ZMR6 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990776|intact:MINT-7985009 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:b7zmr6_mouse(display_long)|uniprotkb:Atxn7l2(gene name)|psi-mi:Atxn7l2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) interpro:IPR013243(SCA7)|mint:MINT-7985435(identity)|uniprotkb:B7ZMR6(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:gUlcNUsYXy+atc1FBy0/am9kGMk10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8BG54 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990643|intact:MINT-7985027|uniprotkb:Q505L2|ensembl:ENSMUSP00000048313|ensembl:ENSMUSP00000105710 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:sptc3_mouse(display_long)|uniprotkb:Sptlc3(gene name)|psi-mi:Sptlc3(display_short)|uniprotkb:Sptlc2l(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Serine-palmityl-CoA transferase 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_780676.1|refseq:XP_006499358.1|ensembl:ENSMUSG00000039092(gene)|ensembl:ENSMUST00000047370(transcript)|ensembl:ENSMUST00000110083(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-MMU-1660661|mint:MINT-7985447(identity)|uniprotkb:Q8BG54(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:alI6Suxhcp/Po9LvxZXGtrmiXoo10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q9CZ05 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990728|intact:MINT-7984961|uniprotkb:Q8VD60|ensembl:ENSMUSP00000106448 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:at7l1_mouse(display_long)|uniprotkb:Atxn7l1(gene name)|psi-mi:Atxn7l1(display_short)|uniprotkb:Atxn7l4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_082415.2|ensembl:ENSMUSG00000020564(gene)|ensembl:ENSMUST00000110824(transcript)|mint:MINT-7985426(identity)|uniprotkb:Q9CZ05(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:DWVqB8g+h61Vt0dYTqL0aolzGaM10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q9DA08 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990274|intact:MINT-4127866|uniprotkb:Q8R0I6|ensembl:ENSMUSP00000032956 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:sgf29_mouse(display_long)|uniprotkb:Sgf29(gene name)|psi-mi:Sgf29(display_short)|uniprotkb:Ccdc101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:XP_017167854.1|refseq:NP_083615.3|ensembl:ENSMUSG00000030714(gene)|ensembl:ENSMUST00000032956(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q9DA08|mint:MINT-7985414(identity)|uniprotkb:Q9DA08(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"Involved in transcriptional regulation, probably through association with histone acetyltransferase (HAT) complexes like the TFTC-HAT or STAGA complexes. May be involved in c-Myc-mediated oncogenic transformation" comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:1DKiknY6Ru9KBYHcjtmI+cCZk2A10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q5DU02 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-7990691|uniprotkb:Q6PDX3|intact:UNK-5437766|uniprotkb:Q3TU34|uniprotkb:Q5SU81|uniprotkb:Q8BJG3|uniprotkb:Q66JV8|uniprotkb:Q3U2W4|ensembl:ENSMUSP00000041263 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:ubp22_mouse(display_long)|uniprotkb:Usp22(gene name)|psi-mi:Usp22(display_short)|uniprotkb:Kiaa1063(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_001004143.2|ensembl:ENSMUSG00000042506(gene)|ensembl:ENSMUST00000041683(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|reactome:R-MMU-5689880|mint:MINT-7985444(identity)|uniprotkb:Q5DU02(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:759fWqKEXkMw0MrHdPoy7sLzUig10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8R2K4 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-2943181|ensembl:ENSMUSP00000135028|uniprotkb:Q8C5T2 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:taf6l_mouse(display_long)|uniprotkb:Taf6l(gene name)|psi-mi:Taf6l(display_short)|uniprotkb:Paf65a(gene name synonym)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) ensembl:ENSMUSG00000003680(gene)|ensembl:ENSMUST00000177056(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|refseq:NP_001171269.1|refseq:NP_666204.2|mint:MINT-7985405(identity)|uniprotkb:Q8R2K4(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:ZBm3hSI6Du2bwabdDbdC/BNgk7E10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8VI33 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-2943311|ensembl:ENSMUSP00000081772|ensembl:ENSMUSP00000132143|ensembl:ENSMUSP00000140244|uniprotkb:Q32P09|uniprotkb:Q80XS3|uniprotkb:Q9CV61 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:taf9_mouse(display_long)|uniprotkb:Taf9(gene name)|psi-mi:Taf9(display_short)|uniprotkb:Taf2g(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) reactome:R-MMU-674695|ensembl:ENSMUSG00000052293(gene)|ensembl:ENSMUSG00000078941(gene)|ensembl:ENSMUST00000084721(transcript)|ensembl:ENSMUST00000167256(transcript)|ensembl:ENSMUST00000190594(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|reactome:R-MMU-6804756|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-MMU-6807505|reactome:R-MMU-73776|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q8VI33|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|refseq:NP_001015889.1|refseq:NP_081415.1|dip:DIP-48737N|mint:MINT-7985411(identity)|uniprotkb:Q8VI33(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:kcrFxMARm/ZQPZ/AnbjtARGYowA10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8R0L9 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-2943209|ensembl:ENSMUSP00000032410|uniprotkb:Q8CIH4|uniprotkb:Q8K289|uniprotkb:Q8R5E3|uniprotkb:Q9CTJ0 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:tada3_mouse(display_long)|uniprotkb:Tada3(gene name)|psi-mi:Tada3(display_short)|uniprotkb:Ada3(gene name synonym)|uniprotkb:Tada3l(gene name synonym)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) ensembl:ENSMUSG00000048930(gene)|ensembl:ENSMUST00000032410(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:Q8R0L9|reactome:R-MMU-5689880|refseq:NP_598693.1|mint:MINT-7985429(identity)|uniprotkb:Q8R0L9(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:0IoyeTJIBrH6bDyjYJsKozMPSC010090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q99LM9 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-2943246|ensembl:ENSMUSP00000027846 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:tada1_mouse(display_long)|uniprotkb:Tada1(gene name)|psi-mi:Tada1(display_short)|uniprotkb:Tada1l(gene name synonym)|uniprotkb:Transcriptional adapter 1-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) ensembl:ENSMUSG00000026563(gene)|ensembl:ENSMUST00000027846(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR024738|refseq:NP_084521.1|mint:MINT-7985441(identity)|uniprotkb:Q99LM9(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:vgBpkRjvhW5d8qgJO1AShblSj6E10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q91WQ5 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-2943161|ensembl:ENSMUSP00000090726|ensembl:ENSMUSP00000128710|uniprotkb:Q8BTL5 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:taf5l_mouse(display_long)|uniprotkb:Taf5l(gene name)|psi-mi:Taf5l(display_short)|uniprotkb:Paf65b(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) ensembl:ENSMUSG00000038697(gene)|ensembl:ENSMUST00000093039(transcript)|ensembl:ENSMUST00000165628(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|refseq:NP_598727.1|refseq:XP_006530609.1|mint:MINT-7985408(identity)|uniprotkb:Q91WQ5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:LEdMv/S43mXJto+rrkJ0fZQXXc410090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80YV3 uniprotkb:Q8K0H5 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 intact:EBI-5744209|uniprotkb:Q8C8H2|uniprotkb:Q9QYY5|ensembl:ENSMUSP00000118105 psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:taf10_mouse(display_long)|uniprotkb:Taf10(gene name)|psi-mi:Taf10(display_short)|uniprotkb:Taf2h(gene name synonym)|uniprotkb:Tafii30(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990741|mint:MINT-7985398|imex:IM-15001-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985399(identity)|uniprotkb:Q80YV3(original identifier) refseq:NP_064408.2|dip:DIP-59890N|ensembl:ENSMUSG00000043866(gene)|ensembl:ENSMUST00000141116(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q8K0H5|reactome:R-MMU-5689880|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|mint:MINT-7985423(identity)|uniprotkb:Q8K0H5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:SF1A F1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 rogid:dpcFKIlnQhWZ8SpD8HJ4uFowyYY10090 intact-crc:7A7CF043CB0BC2D2|rigid:uzIy7dbCmqqFwhpyfRPoGpskbXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8BG54 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990643|intact:MINT-7985027|uniprotkb:Q505L2|ensembl:ENSMUSP00000048313|ensembl:ENSMUSP00000105710 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:sptc3_mouse(display_long)|uniprotkb:Sptlc3(gene name)|psi-mi:Sptlc3(display_short)|uniprotkb:Sptlc2l(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Serine-palmityl-CoA transferase 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_780676.1|refseq:XP_006499358.1|ensembl:ENSMUSG00000039092(gene)|ensembl:ENSMUST00000047370(transcript)|ensembl:ENSMUST00000110083(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-MMU-1660661|mint:MINT-7985550(identity)|uniprotkb:Q8BG54(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:alI6Suxhcp/Po9LvxZXGtrmiXoo10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8CHV6 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985454(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:B7ZMR6 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990776|intact:MINT-7985009 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:b7zmr6_mouse(display_long)|uniprotkb:Atxn7l2(gene name)|psi-mi:Atxn7l2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) interpro:IPR013243(SCA7)|mint:MINT-7985466(identity)|uniprotkb:B7ZMR6(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:gUlcNUsYXy+atc1FBy0/am9kGMk10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9DA08 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990274|intact:MINT-4127866|uniprotkb:Q8R0I6|ensembl:ENSMUSP00000032956 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:sgf29_mouse(display_long)|uniprotkb:Sgf29(gene name)|psi-mi:Sgf29(display_short)|uniprotkb:Ccdc101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:XP_017167854.1|refseq:NP_083615.3|ensembl:ENSMUSG00000030714(gene)|ensembl:ENSMUST00000032956(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q9DA08|mint:MINT-7985544(identity)|uniprotkb:Q9DA08(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"Involved in transcriptional regulation, probably through association with histone acetyltransferase (HAT) complexes like the TFTC-HAT or STAGA complexes. May be involved in c-Myc-mediated oncogenic transformation" comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:1DKiknY6Ru9KBYHcjtmI+cCZk2A10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9CZ05 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990728|intact:MINT-7984961|uniprotkb:Q8VD60|ensembl:ENSMUSP00000106448 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:at7l1_mouse(display_long)|uniprotkb:Atxn7l1(gene name)|psi-mi:Atxn7l1(display_short)|uniprotkb:Atxn7l4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_082415.2|ensembl:ENSMUSG00000020564(gene)|ensembl:ENSMUST00000110824(transcript)|mint:MINT-7985460(identity)|uniprotkb:Q9CZ05(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:DWVqB8g+h61Vt0dYTqL0aolzGaM10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8CHV6 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985556(identity)|uniprotkb:Q8CHV6(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8CID0 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990326|intact:UNK-5517679|uniprotkb:A2ANA8|ensembl:ENSMUSP00000028911 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:csr2b_mouse(display_long)|uniprotkb:Kat14(gene name)|psi-mi:Kat14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:Csrp2bp(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_852082.2|ensembl:ENSMUSG00000027425(gene)|ensembl:ENSMUST00000028911(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0016573"(histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:MINT-7985469(identity)|uniprotkb:Q8CID0(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:bcf5vmJJQM4kTolB7xnf9nyCqOk10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q80YT5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990667|intact:UNK-5501527|ensembl:ENSMUSP00000042572 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:spt20_mouse(display_long)|uniprotkb:Spata20(gene name)|psi-mi:Spata20(display_short)|uniprotkb:Tisp78(gene name synonym)|uniprotkb:Transcript increased in spermiogenesis 78 protein(gene name synonym)|uniprotkb:Sperm-specific protein 411(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_659076.2|ensembl:ENSMUSG00000020867(gene)|ensembl:ENSMUST00000041705(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR004879(Protein of unknown function DUF255)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR024705|interpro:IPR036249|mint:MINT-7985547(identity)|uniprotkb:Q80YT5(original identifier) go:"GO:0005634"(nucleus) - function:May play a role in fertility regulation|comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:O8BITvutVTFM6QfqLgDzUGs3FTk10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9D7W5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985532(identity)|uniprotkb:Q9D7W5(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8VE65 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990784|intact:MINT-4136826|uniprotkb:Q9D8Q0|uniprotkb:Q3V0S7|uniprotkb:Q9CZ11|ensembl:ENSMUSP00000030731 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:taf12_mouse(display_long)|uniprotkb:Taf12(gene name)|psi-mi:Taf12(display_short)|uniprotkb:Transcription initiation factor TFIID 20 kDa subunits(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:XP_017175839.1|dip:DIP-29178N|refseq:NP_079855.2|refseq:XP_006539172.1|refseq:XP_006539173.1|refseq:XP_006539170.2|ensembl:ENSMUSG00000028899(gene)|ensembl:ENSMUST00000030731(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|mint:Q8VE65|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|mint:MINT-7985565(identity)|uniprotkb:Q8VE65(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:"TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription" comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:5G+IyLHK+TK5l4RTTFIPh8B650g10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:A2AWT3 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990620|intact:MINT-7984980|uniprotkb:Q8C1T7|uniprotkb:A2AWT2|uniprotkb:A2AWT4|ensembl:ENSMUSP00000072967|ensembl:ENSMUSP00000102752 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:at7l3_mouse(display_long)|uniprotkb:Atxn7l3(gene name)|psi-mi:Atxn7l3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001092306.1|refseq:NP_001092307.1|ensembl:ENSMUSG00000059995(gene)|ensembl:ENSMUST00000073234(transcript)|ensembl:ENSMUST00000107134(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:MINT-7985463(identity)|uniprotkb:A2AWT3(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:hpFMkpasLzY9LiiFbjAID2EjvMw10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8R4I1 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990748|uniprotkb:E9QPX9|intact:UNK-5525593|uniprotkb:Q8BL17|ensembl:ENSMUSP00000022257|ensembl:ENSMUSP00000152934 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:atx7_mouse(display_long)|uniprotkb:Atxn7(gene name)|psi-mi:Atxn7(display_short)|uniprotkb:Sca7(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 7 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) dip:DIP-29176N|refseq:NP_631973.3|ensembl:ENSMUSG00000021738(gene)|ensembl:ENSMUST00000022257(transcript)|ensembl:ENSMUST00000223880(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR013243(SCA7)|interpro:IPR030706|reactome:R-MMU-5689880|mint:MINT-7985457(identity)|uniprotkb:Q8R4I1(original identifier) go:"GO:0005634"(nucleus) - function:Involved in neurodegeneration. Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation|comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:QxhOtTIxpgF6pvAfVwWQ//A6SY810090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q91WV0 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990301|uniprotkb:Q3UT14|intact:MINT-4610141|ensembl:ENSMUSP00000031190 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:nc2b_mouse(display_long)|uniprotkb:Dr1(gene name)|psi-mi:Dr1(display_short)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_080382.2|ensembl:ENSMUSG00000029265(gene)|ensembl:ENSMUST00000031190(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:MINT-7985535(identity)|uniprotkb:Q91WV0(original identifier) go:"GO:0005634"(nucleus) - function:The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own|comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:IOvFm/PDjH0LRYpn8XRb1V3rZr010090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q5DU02 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7990691|uniprotkb:Q6PDX3|intact:UNK-5437766|uniprotkb:Q3TU34|uniprotkb:Q5SU81|uniprotkb:Q8BJG3|uniprotkb:Q66JV8|uniprotkb:Q3U2W4|ensembl:ENSMUSP00000041263 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:ubp22_mouse(display_long)|uniprotkb:Usp22(gene name)|psi-mi:Usp22(display_short)|uniprotkb:Kiaa1063(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001004143.2|ensembl:ENSMUSG00000042506(gene)|ensembl:ENSMUST00000041683(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|reactome:R-MMU-5689880|mint:MINT-7985580(identity)|uniprotkb:Q5DU02(original identifier) go:"GO:0005634"(nucleus) - comment:mint comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:759fWqKEXkMw0MrHdPoy7sLzUig10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q99K74 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745029|uniprotkb:A3KFP0|uniprotkb:Q8R004|uniprotkb:Q9D277|uniprotkb:Q9WVF1|ensembl:ENSMUSP00000017354 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med24_mouse(display_long)|uniprotkb:Med24(gene name)|psi-mi:Med24(display_short)|uniprotkb:D11Ertd307e(gene name synonym)|uniprotkb:Thrap4(gene name synonym)|uniprotkb:Trap100(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_035999.2|ensembl:ENSMUSG00000017210(gene)|ensembl:ENSMUST00000017354(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR021429|rcsb pdb:6W1S|reactome:R-MMU-212436|refseq:XP_006533368.1|mint:MINT-7985511(identity)|uniprotkb:Q99K74(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:GSdhLyTQrKwK1ya/qhMSzAdmFBg10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9CQ39 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N|mint:MINT-7985505(identity)|uniprotkb:Q9CQ39(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q3TUF7 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5738806|uniprotkb:Q6PGF8|uniprotkb:Q80TI2|uniprotkb:Q8CG86|ensembl:ENSMUSP00000111222 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:yets2_mouse(display_long)|uniprotkb:Yeats2(gene name)|psi-mi:Yeats2(display_short)|uniprotkb:Kiaa1197(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001028409.2|refseq:NP_001139402.1|refseq:XP_006521965.1|ensembl:ENSMUSG00000041215(gene)|ensembl:ENSMUST00000115560(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:MINT-7985586(identity)|uniprotkb:Q3TUF7(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:xiOuCMewv3+xE2m0DSpmdbaK3DY10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9CZ82 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745371|ensembl:ENSMUSP00000099627 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med18_mouse(display_long)|uniprotkb:Med18(gene name)|psi-mi:Med18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_080315.1|ensembl:ENSMUSG00000066042(gene)|ensembl:ENSMUST00000102567(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:6W1S|mint:MINT-7985499(identity)|uniprotkb:Q9CZ82(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:kT/sqHFq4fNAZNniipeC4tP0d2s10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q925J9 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985478(identity)|uniprotkb:Q925J9(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8R0L9 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943209|ensembl:ENSMUSP00000032410|uniprotkb:Q8CIH4|uniprotkb:Q8K289|uniprotkb:Q8R5E3|uniprotkb:Q9CTJ0 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:tada3_mouse(display_long)|uniprotkb:Tada3(gene name)|psi-mi:Tada3(display_short)|uniprotkb:Ada3(gene name synonym)|uniprotkb:Tada3l(gene name synonym)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000048930(gene)|ensembl:ENSMUST00000032410(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:Q8R0L9|reactome:R-MMU-5689880|refseq:NP_598693.1|mint:MINT-7985559(identity)|uniprotkb:Q8R0L9(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:0IoyeTJIBrH6bDyjYJsKozMPSC010090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q5SWW4 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745218|uniprotkb:Q3V3P6|uniprotkb:Q6ZQ90|ensembl:ENSMUSP00000044268 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med13_mouse(display_long)|uniprotkb:Med13(gene name)|psi-mi:Med13(display_short)|uniprotkb:Kiaa0593(gene name synonym)|uniprotkb:Thrap1(gene name synonym)|uniprotkb:Trap240(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001074400.1|dip:DIP-61082N|ensembl:ENSMUSG00000034297(gene)|ensembl:ENSMUST00000043624(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR009401(TRAP240)|interpro:IPR041285|reactome:R-MMU-212436|mint:MINT-7985484(identity)|uniprotkb:Q5SWW4(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:aRRZBYOAGdDeO32VOWKyVHJGZ9w10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8VCD5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N|mint:MINT-7985496(identity)|uniprotkb:Q8VCD5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:RphTDePi36YqZFcRmkcobUnPd7I10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9DB40 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745248|uniprotkb:A2AJV2|uniprotkb:Q78JI3|uniprotkb:Q9D707|ensembl:ENSMUSP00000028139 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med27_mouse(display_long)|uniprotkb:Med27(gene name)|psi-mi:Med27(display_short)|uniprotkb:Crsp8(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Mediator complex subunit 27(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_083891.1|refseq:NP_081172.2|refseq:NP_001277419.1|ensembl:ENSMUSG00000026799(gene)|ensembl:ENSMUST00000028139(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q9DB40|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985517(identity)|uniprotkb:Q9DB40(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:3qxK1h1BWs2YxdQZkqUWn3G2vDE10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9CQA5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745428|uniprotkb:Q3UL96|uniprotkb:Q8BVG6|ensembl:ENSMUSP00000022705 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med4_mouse(display_long)|uniprotkb:Med4(gene name)|psi-mi:Med4(display_short)|uniprotkb:Vdrip(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_080395.1|ensembl:ENSMUSG00000022109(gene)|ensembl:ENSMUST00000022705(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9CQA5|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985526(identity)|uniprotkb:Q9CQA5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:mxprXZb8/S6/jNJVDSvApugwGiQ10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8R2K4 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943181|ensembl:ENSMUSP00000135028|uniprotkb:Q8C5T2 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:taf6l_mouse(display_long)|uniprotkb:Taf6l(gene name)|psi-mi:Taf6l(display_short)|uniprotkb:Paf65a(gene name synonym)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000003680(gene)|ensembl:ENSMUST00000177056(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|refseq:NP_001171269.1|refseq:NP_666204.2|mint:MINT-7985571(identity)|uniprotkb:Q8R2K4(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:ZBm3hSI6Du2bwabdDbdC/BNgk7E10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q91WQ5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943161|ensembl:ENSMUSP00000090726|ensembl:ENSMUSP00000128710|uniprotkb:Q8BTL5 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:taf5l_mouse(display_long)|uniprotkb:Taf5l(gene name)|psi-mi:Taf5l(display_short)|uniprotkb:Paf65b(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000038697(gene)|ensembl:ENSMUST00000093039(transcript)|ensembl:ENSMUST00000165628(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|refseq:NP_598727.1|refseq:XP_006530609.1|mint:MINT-7985568(identity)|uniprotkb:Q91WQ5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:LEdMv/S43mXJto+rrkJ0fZQXXc410090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9R0X0 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985502(identity)|uniprotkb:Q9R0X0(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8CFI7 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2549877|ensembl:ENSMUSP00000031167 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N|mint:MINT-7985541(identity)|uniprotkb:Q8CFI7(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q924H2 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-6260935|ensembl:ENSMUSP00000012259|uniprotkb:G3X8S4 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med15_mouse(display_long)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Pcqap(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:Med15(gene name)|psi-mi:Med15(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000012114(gene)|ensembl:ENSMUST00000012259(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|interpro:IPR019087|interpro:IPR036529|mint:Q924H2|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-59237N|refseq:NP_291087.2|mint:MINT-7985490(identity)|uniprotkb:Q924H2(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:mZasSGGG3iCf4B+EFvrHwfeRm0I10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:P08775 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N|mint:MINT-7985538(identity)|uniprotkb:P08775(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:A2AGH6 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5744969|uniprotkb:A2AGH7|uniprotkb:O88542|uniprotkb:Q571H3|uniprotkb:Q6PGB4|uniprotkb:Q6PGD8|ensembl:ENSMUSP00000085260 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med12_mouse(display_long)|uniprotkb:Med12(gene name)|psi-mi:Med12(display_short)|uniprotkb:Kiaa0192(gene name synonym)|uniprotkb:Mopa(gene name synonym)|uniprotkb:Tnrc11(gene name synonym)|uniprotkb:Trap230(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_067496.2|go:"GO:0048568"(embryonic organ development)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:A2AGH6|reactome:R-MMU-212436|ensembl:ENSMUSG00000079487(gene)|ensembl:ENSMUST00000087948(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|dip:DIP-59233N|mint:MINT-7985481(identity)|uniprotkb:A2AGH6(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:9l10cOqNn+PIwL7gQq/WsgiZnLE10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q6PGF3 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-6260816|uniprotkb:E9QM81 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med16_mouse(display_long)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thrap5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:Q6PGF3|dip:DIP-48408N|mint:MINT-7985493(identity)|uniprotkb:Q6PGF3(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:7RYpXMMTPBtLxPGifdlY+MdwlEM10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9CXU1 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985523(identity)|uniprotkb:Q9CXU1(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8VI33 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943311|ensembl:ENSMUSP00000081772|ensembl:ENSMUSP00000132143|ensembl:ENSMUSP00000140244|uniprotkb:Q32P09|uniprotkb:Q80XS3|uniprotkb:Q9CV61 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:taf9_mouse(display_long)|uniprotkb:Taf9(gene name)|psi-mi:Taf9(display_short)|uniprotkb:Taf2g(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) reactome:R-MMU-674695|ensembl:ENSMUSG00000052293(gene)|ensembl:ENSMUSG00000078941(gene)|ensembl:ENSMUST00000084721(transcript)|ensembl:ENSMUST00000167256(transcript)|ensembl:ENSMUST00000190594(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|reactome:R-MMU-6804756|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-MMU-6807505|reactome:R-MMU-73776|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q8VI33|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|refseq:NP_001015889.1|refseq:NP_081415.1|dip:DIP-48737N|mint:MINT-7985574(identity)|uniprotkb:Q8VI33(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:kcrFxMARm/ZQPZ/AnbjtARGYowA10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q920D3 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-309215|uniprotkb:Q3U4G7|uniprotkb:Q9CQF2|ensembl:ENSMUSP00000115882 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med28_mouse(display_long)|uniprotkb:Med28(gene name)|psi-mi:Med28(display_short)|uniprotkb:Fksg20(orf name)|uniprotkb:Mediator complex subunit 28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_080171.1|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q920D3|rcsb pdb:6W1S|ensembl:ENSMUSG00000015804(gene)|ensembl:ENSMUST00000156481(transcript)|mint:MINT-7985520(identity)|uniprotkb:Q920D3(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:U69QDqUxcl7UWjo7qkiZKN5wwCg10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q7TN02 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436|mint:MINT-7985514(identity)|uniprotkb:Q7TN02(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:A2ABV5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5744924|uniprotkb:Q3TQU3|uniprotkb:Q6P1H5|uniprotkb:Q9R0T1|uniprotkb:Q9WTN9|ensembl:ENSMUSP00000094239 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med14_mouse(display_long)|uniprotkb:Med14(gene name)|psi-mi:Med14(display_short)|uniprotkb:Crsp2(gene name synonym)|uniprotkb:Gm641(gene name synonym)|uniprotkb:Trap170(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001041673.1|refseq:NP_036135.3|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:6W1S|reactome:R-MMU-212436|ensembl:ENSMUSG00000064127(gene)|ensembl:ENSMUST00000096495(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:MINT-7985487(identity)|uniprotkb:A2ABV5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:zYS7ClZGBQS0njhhSZ9xew2FSLI10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q99LQ1 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-688604|uniprotkb:Q3TBM3|ensembl:ENSMUSP00000021416 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:mbip1_mouse(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:Mbip(gene name)|psi-mi:Mbip(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_663417.1|ensembl:ENSMUSG00000021028(gene)|ensembl:ENSMUST00000021416(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q99LQ1|mint:MINT-7985475(identity)|uniprotkb:Q99LQ1(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:KtWoLiw2udaTSOzc3EHifvyF45M10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q99LM9 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943246|ensembl:ENSMUSP00000027846 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:tada1_mouse(display_long)|uniprotkb:Tada1(gene name)|psi-mi:Tada1(display_short)|uniprotkb:Tada1l(gene name synonym)|uniprotkb:Transcriptional adapter 1-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000026563(gene)|ensembl:ENSMUST00000027846(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR024738|refseq:NP_084521.1|mint:MINT-7985553(identity)|uniprotkb:Q99LM9(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:vgBpkRjvhW5d8qgJO1AShblSj6E10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q8K0H5 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5744209|uniprotkb:Q8C8H2|uniprotkb:Q9QYY5|ensembl:ENSMUSP00000118105 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:taf10_mouse(display_long)|uniprotkb:Taf10(gene name)|psi-mi:Taf10(display_short)|uniprotkb:Taf2h(gene name synonym)|uniprotkb:Tafii30(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_064408.2|dip:DIP-59890N|ensembl:ENSMUSG00000043866(gene)|ensembl:ENSMUST00000141116(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q8K0H5|reactome:R-MMU-5689880|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|mint:MINT-7985562(identity)|uniprotkb:Q8K0H5(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:dpcFKIlnQhWZ8SpD8HJ4uFowyYY10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q6KAQ7 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5737882|uniprotkb:Q3TMK6|uniprotkb:Q3V189|ensembl:ENSMUSP00000101706|ensembl:ENSMUSP00000101707 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:zzz3_mouse(display_long)|uniprotkb:Zzz3(gene name)|psi-mi:Zzz3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001074224.1|refseq:XP_006500911.1|refseq:XP_006500913.1|refseq:XP_006500914.1|refseq:XP_006500919.1|refseq:XP_006500920.1|refseq:NP_001333584.1|refseq:XP_017174912.1|ensembl:ENSMUSG00000039068(gene)|ensembl:ENSMUST00000106100(transcript)|ensembl:ENSMUST00000106101(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|mint:MINT-7985589(identity)|uniprotkb:Q6KAQ7(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:ed0sQkhcg/sF4D2uu6Fnw+WzCzA10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:P61965 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-1247084|uniprotkb:Q91VA5|uniprotkb:Q922C9|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|ensembl:ENSMUSP00000109585 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:wdr5_mouse(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)|uniprotkb:Big(gene name synonym)|uniprotkb:Big3(gene name synonym)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WD repeat-containing protein BIG-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_543124.1|refseq:XP_006497735.1|dip:DIP-38618N|ensembl:ENSMUSG00000026917(gene)|ensembl:ENSMUST00000113952(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61965|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-8936459|reactome:R-MMU-8951664|mint:MINT-7985583(identity)|uniprotkb:P61965(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q80YQ2 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745001|uniprotkb:Q6ZPV7|uniprotkb:Q8CEC3|uniprotkb:Q8K587|uniprotkb:Q9CXY8 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med23_mouse(display_long)|uniprotkb:Med23(gene name)|psi-mi:Med23(display_short)|uniprotkb:Crsp3(gene name synonym)|uniprotkb:Kiaa1216(gene name synonym)|uniprotkb:Sur2(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_001159888.1|refseq:NP_081623.3|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:2000409"(positive regulation of T cell extravasation)|interpro:IPR021629|rcsb pdb:6W1S|dip:DIP-59234N|reactome:R-MMU-212436|mint:MINT-7985508(identity)|uniprotkb:Q80YQ2(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:unJwhtOAP16TniaelImM6E3JM8o10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q921D4 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745383|uniprotkb:Q3TAK5|uniprotkb:Q8BTP9|ensembl:ENSMUSP00000125156 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med6_mouse(display_long)|uniprotkb:Med6(gene name)|psi-mi:Med6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) refseq:NP_081489.2|refseq:NP_001334313.1|refseq:NP_001334315.1|dip:DIP-60703N|ensembl:ENSMUSG00000002679(gene)|ensembl:ENSMUST00000161211(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-7985529(identity)|uniprotkb:Q921D4(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:zmKsMA5JwAtTd32b4TAbAnwHmxs10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q9JHD2 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985472(identity)|uniprotkb:Q9JHD2(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9JHD2 uniprotkb:Q80YV3 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7990879|mint:MINT-7985450|imex:IM-15001-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985451(identity)|uniprotkb:Q9JHD2(original identifier) go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3|mint:MINT-7985577(identity)|uniprotkb:Q80YV3(original identifier) go:"GO:0005634"(nucleus) - - comment:homomint|comment:mint|figure legend:T1 SF1A F1B F1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2018/02/26 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 intact-crc:12EF0BC2E552B345|rigid:2FXQmCJmt57RPNv7iDOFqQ+O+ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8CHV6 uniprotkb:Q9JHD1 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2325611|uniprotkb:Q3U142|uniprotkb:Q640M9|ensembl:ENSMUSP00000000724 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2b_mouse(display_long)|uniprotkb:Pcaf(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:Kat2b(gene name)|psi-mi:Kat2b(display_short)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991091|mint:MINT-7985618|imex:IM-15001-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985622(identity) refseq:NP_064389.2|dip:DIP-29281N|ensembl:ENSMUSG00000000708(gene)|ensembl:ENSMUST00000000724(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042311"(vasodilation)|go:"GO:0042641"(actomyosin)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:2000233"(negative regulation of rRNA processing)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD1|rcsb pdb:5ML0|reactome:R-MMU-2032785|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-5689901|reactome:R-MMU-8936459|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-9617629|mint:MINT-7985624(identity) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" caution:This sequence has been withdrawn from Uniprot. figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:xnaxRvvz5/uqJD0Zt6tnXNQJ43g10090 intact-crc:75071E2A231FE453|rigid:EMSMtD2sfdJcdXGVtFfHL0Hu2OQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CHV6 uniprotkb:Q9JHD2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991149|mint:MINT-7985592|imex:IM-15001-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985596(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985594(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:f1d f2a|comment:"the same interaction has been detected in several mouse cell lines: ES, MEF and FL83B."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:AC51D4A2B8F3116D|rigid:UopMqwmPn0oW9GIZGhX6ozKO8OY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q925J9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991149|mint:MINT-7985592|imex:IM-15001-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985596(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985595(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - comment:homomint|comment:mint|figure legend:f1d f2a|comment:"the same interaction has been detected in several mouse cell lines: ES, MEF and FL83B."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:AC51D4A2B8F3116D|rigid:UopMqwmPn0oW9GIZGhX6ozKO8OY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9JHD2 uniprotkb:Q8R4U7 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-7991189|uniprotkb:Q8BQW1|uniprotkb:Q7TS71|uniprotkb:Q9CSL6|uniprotkb:Q99NG3|intact:MINT-4119192|uniprotkb:A3KG96|uniprotkb:Q3UV18|ensembl:ENSMUSP00000001116|ensembl:ENSMUSP00000060619|ensembl:ENSMUSP00000101475|ensembl:ENSMUSP00000130758 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:luzp1_mouse(display_long)|uniprotkb:Luzp1(gene name)|psi-mi:Luzp1(display_short)|uniprotkb:Luzp(gene name synonym)|uniprotkb:Leucine zipper motif-containing protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991224|mint:MINT-7985678|imex:IM-15001-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985684(identity) refseq:NP_077772.2|refseq:XP_006538984.1|ensembl:ENSMUSG00000001089(gene)|ensembl:ENSMUST00000001116(transcript)|ensembl:ENSMUST00000063021(transcript)|ensembl:ENSMUST00000105849(transcript)|ensembl:ENSMUST00000170102(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|interpro:IPR026734|mint:Q8R4U7|mint:MINT-7985686(identity) - - comment:mint figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:iDQj2aaSiq5/yW5J1vZ3YnF8ru410090 intact-crc:FC72306E168076A2|rigid:n0P0P0tEmx+tF5UJ/zrh9EJdYzg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9JHD2 uniprotkb:Q925J9 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991224|mint:MINT-7985678|imex:IM-15001-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985684(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985680(identity) - - - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:FC72306E168076A2|rigid:n0P0P0tEmx+tF5UJ/zrh9EJdYzg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q9JHD2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991165|mint:MINT-7985656|imex:IM-15001-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985660(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985662(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:57461AED94E623A1|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q925J9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991165|mint:MINT-7985656|imex:IM-15001-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985660(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985658(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:57461AED94E623A1|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q7TN02 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991165|mint:MINT-7985656|imex:IM-15001-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985660(identity) refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436|mint:MINT-7985704(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:57461AED94E623A1|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q8R4U7 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-7991189|uniprotkb:Q8BQW1|uniprotkb:Q7TS71|uniprotkb:Q9CSL6|uniprotkb:Q99NG3|intact:MINT-4119192|uniprotkb:A3KG96|uniprotkb:Q3UV18|ensembl:ENSMUSP00000001116|ensembl:ENSMUSP00000060619|ensembl:ENSMUSP00000101475|ensembl:ENSMUSP00000130758 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:luzp1_mouse(display_long)|uniprotkb:Luzp1(gene name)|psi-mi:Luzp1(display_short)|uniprotkb:Luzp(gene name synonym)|uniprotkb:Leucine zipper motif-containing protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991183|mint:MINT-7985665|imex:IM-15001-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985669(identity) refseq:NP_077772.2|refseq:XP_006538984.1|ensembl:ENSMUSG00000001089(gene)|ensembl:ENSMUST00000001116(transcript)|ensembl:ENSMUST00000063021(transcript)|ensembl:ENSMUST00000105849(transcript)|ensembl:ENSMUST00000170102(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|interpro:IPR026734|mint:Q8R4U7|mint:MINT-7985675(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" comment:mint figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:iDQj2aaSiq5/yW5J1vZ3YnF8ru410090 intact-crc:B383A66D27F21AF1|rigid:4pK3zneMExoNUOfWGkjSYZ/5rrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q9JHD2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991183|mint:MINT-7985665|imex:IM-15001-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985669(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985671(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:B383A66D27F21AF1|rigid:4pK3zneMExoNUOfWGkjSYZ/5rrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q925J9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991183|mint:MINT-7985665|imex:IM-15001-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985669(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985667(identity) - comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:B383A66D27F21AF1|rigid:4pK3zneMExoNUOfWGkjSYZ/5rrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q925J9 uniprotkb:Q7TN02 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991273|mint:MINT-7985718|imex:IM-15001-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985720(identity) refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436|mint:MINT-7985726(identity) - - - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:F2B2CFBF6B7C3619|rigid:SFojCemBLuOccrtoNngxhY36T9Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q925J9 uniprotkb:Q9JHD2 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991273|mint:MINT-7985718|imex:IM-15001-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985720(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985724(identity) - - - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:F2B2CFBF6B7C3619|rigid:SFojCemBLuOccrtoNngxhY36T9Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R4U7 uniprotkb:Q9JHD2 intact:EBI-7991189|uniprotkb:Q8BQW1|uniprotkb:Q7TS71|uniprotkb:Q9CSL6|uniprotkb:Q99NG3|intact:MINT-4119192|uniprotkb:A3KG96|uniprotkb:Q3UV18|ensembl:ENSMUSP00000001116|ensembl:ENSMUSP00000060619|ensembl:ENSMUSP00000101475|ensembl:ENSMUSP00000130758 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:luzp1_mouse(display_long)|uniprotkb:Luzp1(gene name)|psi-mi:Luzp1(display_short)|uniprotkb:Luzp(gene name synonym)|uniprotkb:Leucine zipper motif-containing protein(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991239|mint:MINT-7985692|imex:IM-15001-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077772.2|refseq:XP_006538984.1|ensembl:ENSMUSG00000001089(gene)|ensembl:ENSMUST00000001116(transcript)|ensembl:ENSMUST00000063021(transcript)|ensembl:ENSMUST00000105849(transcript)|ensembl:ENSMUST00000170102(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|interpro:IPR026734|mint:Q8R4U7|mint:MINT-7985698(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985696(identity) - comment:mint - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:iDQj2aaSiq5/yW5J1vZ3YnF8ru410090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:90DEBAC63682FC09|rigid:n0P0P0tEmx+tF5UJ/zrh9EJdYzg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R4U7 uniprotkb:Q925J9 intact:EBI-7991189|uniprotkb:Q8BQW1|uniprotkb:Q7TS71|uniprotkb:Q9CSL6|uniprotkb:Q99NG3|intact:MINT-4119192|uniprotkb:A3KG96|uniprotkb:Q3UV18|ensembl:ENSMUSP00000001116|ensembl:ENSMUSP00000060619|ensembl:ENSMUSP00000101475|ensembl:ENSMUSP00000130758 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:luzp1_mouse(display_long)|uniprotkb:Luzp1(gene name)|psi-mi:Luzp1(display_short)|uniprotkb:Luzp(gene name synonym)|uniprotkb:Leucine zipper motif-containing protein(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991239|mint:MINT-7985692|imex:IM-15001-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077772.2|refseq:XP_006538984.1|ensembl:ENSMUSG00000001089(gene)|ensembl:ENSMUST00000001116(transcript)|ensembl:ENSMUST00000063021(transcript)|ensembl:ENSMUST00000105849(transcript)|ensembl:ENSMUST00000170102(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|interpro:IPR026734|mint:Q8R4U7|mint:MINT-7985698(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985694(identity) - comment:mint - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:iDQj2aaSiq5/yW5J1vZ3YnF8ru410090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:90DEBAC63682FC09|rigid:n0P0P0tEmx+tF5UJ/zrh9EJdYzg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q925J9 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991254|mint:MINT-7985707|imex:IM-15001-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985711(identity) ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564|mint:MINT-7985709(identity) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:A1F3E791DAE121C6|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q7TN02 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991254|mint:MINT-7985707|imex:IM-15001-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985711(identity) refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436|mint:MINT-7985715(identity) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:A1F3E791DAE121C6|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CHV6 uniprotkb:Q9JHD2 intact:EBI-7990347|uniprotkb:Q8BNK0|intact:MINT-4606424|uniprotkb:Q3TZD7|uniprotkb:Q8R3H5|ensembl:ENSMUSP00000018795 intact:EBI-2943116|uniprotkb:Q3TZ59|ensembl:ENSMUSP00000099407 psi-mi:tad2a_mouse(display_long)|uniprotkb:Tada2a(gene name)|psi-mi:Tada2a(display_short)|uniprotkb:Tada2l(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym) psi-mi:kat2a_mouse(display_long)|uniprotkb:Kat2a(gene name)|psi-mi:Kat2a(display_short)|uniprotkb:Gcn5l2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991254|mint:MINT-7985707|imex:IM-15001-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766150.1|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2AQE|rcsb pdb:2AQF|rcsb pdb:2CUJ|ensembl:ENSMUSG00000018651(gene)|ensembl:ENSMUST00000018795(transcript)|go:"GO:0000125"|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|mint:MINT-7985711(identity) ensembl:ENSMUSG00000020918(gene)|ensembl:ENSMUST00000103118(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0007399"(nervous system development)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD2|rcsb pdb:7BY1|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-8941856|reactome:R-MMU-5689880|refseq:NP_064388.2|dip:DIP-29180N|mint:MINT-7985713(identity) go:"GO:0005634"(nucleus) comment:mint|function:"Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling" - figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2010/07/23 2014/10/16 rogid:Tw3RNnXegcUgYVoDJhjXKW6kgKI10090 rogid:hBMAmuZMuoxU1uoqaeHLoSbPies10090 intact-crc:A1F3E791DAE121C6|rigid:AH55geDXnVLj0wrNM9EhOgBh2OM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O75478 uniprotkb:Q92830 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991315|mint:MINT-7985641|imex:IM-15001-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|mint:MINT-7985645(identity) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N|mint:MINT-7985647(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/07/23 2014/10/16 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 intact-crc:C2FABB7ACD291644|rigid:V/b6Faw3dFeNidj1cwiQhZyIUJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O75478 uniprotkb:Q15648 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Krebs et al. (2010) pubmed:20508642|imex:IM-15001|mint:MINT-7985048|doi:10.1038/embor.2010.75 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7991315|mint:MINT-7985641|imex:IM-15001-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|mint:MINT-7985645(identity) refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N|mint:MINT-7985643(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/07/23 2014/10/16 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 intact-crc:C2FABB7ACD291644|rigid:V/b6Faw3dFeNidj1cwiQhZyIUJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)