#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q58A65 uniprotkb:P62331 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986227|mint:MINT-7892289|imex:IM-15529-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892292(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892291(identity) - - - figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/10 2014/10/16 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:2533634A33314699|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false glutathione s tranferase tag:?-?(MINT-7892310) mutation disrupting interaction:27-27(MINT-7892306)|flag tag:?-?(MINT-7892300) - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0820"(molecular weight estimation by sybr staining) uniprotkb:P62331 uniprotkb:Q9ESN9 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:"MI:0096"(pull down) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986308|mint:MINT-7892509|imex:IM-15529-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892511(identity) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892517(identity) - - - figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 intact-crc:AFB50579E3C95FB3|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false flag tag:?-?(MINT-7892514)|mutation decreasing interaction:27-27(MINT-7892512) glutathione s tranferase tag:?-?(MINT-7892518) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0096"(pull down) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986287|mint:MINT-7892314|imex:IM-15529-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892316(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892322(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:AF014770342A5218|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false mutation decreasing interaction:27-27(MINT-7892317)|flag tag:?-?(MINT-7892319) glutathione s tranferase tag:?-?(MINT-7892323) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P62331 uniprotkb:Q9ESN9 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:"MI:0096"(pull down) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7986356|mint:MINT-7892770|imex:IM-15529-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892772(identity) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892778(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:sf1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 intact-crc:4ADDC021C3DD8D2B|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false flag tag:?-?(MINT-7892773)|mutation disrupting interaction:27-27(MINT-7892775) binding-associated region:425-480(MINT-7892789)|glutathione s tranferase tag:?-?(MINT-7892779) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q58A65 uniprotkb:P62331 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7986330|mint:MINT-7892755|imex:IM-15529-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892763(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892757(identity) - - - comment:domino|comment:mint|figure legend:sf1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/10 2014/10/16 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:533E13CB83324AA3|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false glutathione s tranferase tag:?-?(MINT-7892764)|binding-associated region:399-460(MINT-7892783) flag tag:?-?(MINT-7892760)|mutation disrupting interaction:27-27(MINT-7892758) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986526|mint:MINT-7892333|imex:IM-15529-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892335(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892341(identity) - - - comment:mint|figure legend:f1d f1e f2b f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:6199C9537C2C7D2F|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false flag tag:?-?(MINT-7892338)|mutation disrupting interaction:27-27(MINT-7892336)|binding-associated region:12-175(MINT-7892506) green fluorescent protein tag:?-?(MINT-7892342) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q9ESN9 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986550|mint:MINT-7892353|imex:IM-15529-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892355(identity) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892361(identity) - - - comment:homomint|comment:mint|figure legend:f1d f1e f2b f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 intact-crc:027314F189AAB3F7|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false mutation disrupting interaction:27-27(MINT-7892356)|flag tag:?-?(MINT-7892358)|binding-associated region:12-175(MINT-7892500) green fluorescent protein tag:?-?(MINT-7892489) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986575|mint:MINT-7892522|imex:IM-15529-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892524(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892532(identity) - - - comment:mint|figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:EB765FFA81EBF16B|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false mutation disrupting interaction:60-60(MINT-7892545)|mutation disrupting interaction:58-58(MINT-7892542)|mutation disrupting interaction:53-53(MINT-7892539)|flag tag:?-?(MINT-7892529) green fluorescent protein tag:?-?(MINT-7892533) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ESN9 uniprotkb:P62331 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986604|mint:MINT-7892549|imex:IM-15529-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892565(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892551(identity) - - - comment:homomint|comment:mint|figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:52E1D5053DF86526|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false green fluorescent protein tag:?-?(MINT-7892566) flag tag:?-?(MINT-7892558)|mutation disrupting interaction:60-60(MINT-7892552)|mutation disrupting interaction:53-53(MINT-7892556)|mutation disrupting interaction:58-58(MINT-7892554) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q58A65 uniprotkb:P62331 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986652|mint:MINT-7892573|imex:IM-15529-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892587(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892575(identity) - - - figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:FBFD9BA7F5603991|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false green fluorescent protein tag:?-?(MINT-7892588) flag tag:?-?(MINT-7892582)|mutation decreasing interaction:53-53(MINT-7892580) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q58A65 uniprotkb:P62331 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986701|mint:MINT-7892594|imex:IM-15529-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892604(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892596(identity) - - - figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:B2A2DCBFC77EF0AC|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false green fluorescent protein tag:?-?(MINT-7892605) flag tag:?-?(MINT-7892599)|mutation decreasing interaction:19-19(MINT-7892601) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986765|mint:MINT-7892629|imex:IM-15529-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892631(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892637(identity) - - - figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:D2BC1F40457214D5|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false mutation decreasing interaction:60-60(MINT-7892634)|flag tag:?-?(MINT-7892632) green fluorescent protein tag:?-?(MINT-7892638) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ESN9 uniprotkb:P62331 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986733|mint:MINT-7892615|imex:IM-15529-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892623(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892617(identity) - - - figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:A45D908C384BAE89|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false green fluorescent protein tag:?-?(MINT-7892624) mutation decreasing interaction:58-58(MINT-7892618)|flag tag:?-?(MINT-7892620) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESN9 uniprotkb:P62331 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986848|mint:MINT-7892657|imex:IM-15529-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892665(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892659(identity) - - - figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:A40254A1B24E8606|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false green fluorescent protein tag:?-?(MINT-7892666) mutation decreasing interaction:19-19(MINT-7892660)|flag tag:?-?(MINT-7892662) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986827|mint:MINT-7892644|imex:IM-15529-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892646(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892652(identity) - - - figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:12916EA1C3349995|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false flag tag:?-?(MINT-7892647)|mutation decreasing interaction:58-58(MINT-7892649) green fluorescent protein tag:?-?(MINT-7892653) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ESN9 uniprotkb:P62331 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986870|mint:MINT-7892672|imex:IM-15529-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892680(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892674(identity) - - - figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:7D26139AAC3C4CE9|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false green fluorescent protein tag:?-?(MINT-7892681) mutation decreasing interaction:53-53(MINT-7892675)|flag tag:?-?(MINT-7892677) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62331 uniprotkb:O70161 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986892|mint:MINT-7892698|imex:IM-15529-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892700(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-7892708(identity) - - - figure legend:f2e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:E636D887982E85EF|rigid:rm76DG4UwKfVKKE2rwXt5q+5esk false ha tag:?-?(MINT-7892705) flag tag:?-?(MINT-7892709) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q58A65 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-6530207|uniprotkb:Q3UH77|uniprotkb:Q3UHF0|uniprotkb:Q58VQ4|uniprotkb:Q5NC70|uniprotkb:Q5NC78|uniprotkb:Q6A057|uniprotkb:Q6PAS3|uniprotkb:Q8CJC2 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_mouse(display_long)|uniprotkb:Spag9(gene name)|psi-mi:Spag9(display_short)|uniprotkb:Jip4(gene name synonym)|uniprotkb:Jsap2(gene name synonym)|uniprotkb:Kiaa0516(gene name synonym)|uniprotkb:Mapk8ip4(gene name synonym)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986927|mint:MINT-7892716|imex:IM-15529-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892718(identity) refseq:NP_001186133.1|refseq:NP_001186134.1|refseq:NP_081845.2|refseq:NP_001020599.1|refseq:NP_001020600.1|refseq:NP_001020601.1|refseq:NP_001186132.1|interpro:IPR039911|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:1903860"(negative regulation of dendrite extension)|reactome:R-MMU-525793|interpro:IPR019143|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034743|interpro:IPR034744|refseq:XP_006534282.1|interpro:IPR032486|mint:Q58A65|interpro:IPR036322|mint:MINT-7892726(identity) - - - comment:domino|comment:mint|figure legend:sf1b sf1c sf1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:S+s6djFmdfKHPKHjSzRYIY8wvTM10090 intact-crc:55836F4034252C3F|rigid:0G5itIgWC4Hl6AZYw9ZChOGuBu8 false mutation decreasing interaction:27-27(MINT-7892721)|flag tag:?-?(MINT-7892723) binding-associated region:399-460(MINT-7892734)|green fluorescent protein tag:?-?(MINT-7892727) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q9ESN9 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Suzuki et al. (2010) pubmed:20493856|imex:IM-15529|mint:MINT-7892225|doi:10.1016/j.febslet.2010.05.020 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7986953|mint:MINT-7892738|imex:IM-15529-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-7892740(identity) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2|mint:MINT-7892746(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:sf1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2010/05/10 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090 intact-crc:E91921452A93B4D0|rigid:lyE9B/LAHe8ffZ6fOvNg6/ASHwM false flag tag:?-?(MINT-7892743)|mutation decreasing interaction:27-27(MINT-7892741) green fluorescent protein tag:?-?(MINT-7892750)|binding-associated region:425-480(MINT-7892747) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)