#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979681|mint:MINT-7950045|imex:IM-15065-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950047(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950048(identity)	-	-	crc64:A81833C7F60F5202	figure legend:sf1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:4893FA009E7358F9|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	mutation decreasing interaction:?-?(MINT-7950055)	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979741|mint:MINT-7978934|imex:IM-15065-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7978940(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7978936(identity)	-	crc64:A81833C7F60F5202	-	figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:0A6468859C05B6D4|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	mutation increasing interaction:441-441(MINT-7978943)	glutathione s tranferase tag:?-?(MINT-7978937)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979717|mint:MINT-7978909|imex:IM-15065-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7978911(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7978923(identity)	-	-	crc64:A81833C7F60F5202	figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:C2FC55F3124610A7|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	glutathione s tranferase tag:?-?(MINT-7978920)	mutation increasing interaction:441-442(MINT-7978929)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:Q1AE18	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-7979781|intact:MINT-7978973	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:q1ae18_mumiv(display_long)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:10794(mvm)|taxid:10794(Murine minute virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979786|mint:MINT-7978960|imex:IM-15065-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7978962(identity)	mint:MINT-7978976(identity)	-	crc64:C9D027033F8C70E1	comment:mint	comment:homomint|comment:mint|figure legend:f6b sf3a sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:9A8fc6km8JsT2chgvS1vSK8qzUY10794	intact-crc:1F84EF50FE388CEF|rigid:07MAdoqc2mOZ/MWRRAsGgjIvu7Q	false	glutathione s tranferase tag:?-?(MINT-7978963)	tandem tag:?-?(MINT-7978979)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:P30822	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979786|mint:MINT-7978960|imex:IM-15065-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7978962(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7978966(identity)	-	crc64:C9D027033F8C70E1	crc64:A81833C7F60F5202	comment:homomint|comment:mint|figure legend:f6b sf3a sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:1F84EF50FE388CEF|rigid:07MAdoqc2mOZ/MWRRAsGgjIvu7Q	false	glutathione s tranferase tag:?-?(MINT-7978963)	binding-associated region:1-377,413-1084(MINT-7978986)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979761|mint:MINT-7978948|imex:IM-15065-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7978954(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7978950(identity)	-	crc64:A81833C7F60F5202	-	figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:C30BB93268A6E120|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	mutation increasing interaction:443-443(MINT-7978955)	glutathione s tranferase tag:?-?(MINT-7978951)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:P41920	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-29523|uniprotkb:D6VRY9|ensemblfungi:YDR002W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:yrb1_yeast(display_long)|uniprotkb:CST20(gene name synonym)|uniprotkb:YRB1(gene name)|psi-mi:YRB1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)|uniprotkb:Perinuclear array-localized protein(gene name synonym)|uniprotkb:Chromosome stability protein 20(gene name synonym)|uniprotkb:HTN1(gene name synonym)|uniprotkb:SFO1(gene name synonym)|uniprotkb:YDR002W(locus name)|uniprotkb:YD8119.08(orf name)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979836|mint:MINT-7979012|imex:IM-15065-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7979019(identity)	refseq:NP_010285.1|sgd:S000002409|dip:DIP-838N|ensemblfungi:YDR002W(gene)|ensemblfungi:YDR002W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3M1I|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4WVF|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|mint:MINT-7979023(identity)	-	crc64:C9D027033F8C70E1	crc64:46C3766B0906A75B	figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:my2AY/L5hSkeYhsyWGTQA3s27Ak559292	intact-crc:1F90924C18E9DE94|rigid:g4IQXux6+i0iESpxlQX+0/1OdRA	false	glutathione s tranferase tag:?-?(MINT-7979020)	binding-associated region:11-201(MINT-7979024)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:P11745	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-15648|uniprotkb:D6W061|ensemblfungi:YMR235C	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:rna1_yeast(display_long)|uniprotkb:YM9959.17C(orf name)|uniprotkb:RNA1(gene name)|psi-mi:RNA1(display_short)|uniprotkb:YMR235C(locus name)|uniprotkb:Protein involved in RNA production/processing(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979836|mint:MINT-7979012|imex:IM-15065-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7979019(identity)	refseq:NP_013962.1|sgd:S000004848|ensemblfungi:YMR235C(gene)|ensemblfungi:YMR235C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006404"(RNA import into nucleus)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|dip:DIP-2509N|reactome:R-SCE-3108232|reactome:R-SCE-9615933|mint:MINT-7979014(identity)	-	crc64:C9D027033F8C70E1	crc64:D77029B6783FFF09	figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:OxR3vTmmx+chQ1Gvcc2nweFGFII559292	intact-crc:1F90924C18E9DE94|rigid:g4IQXux6+i0iESpxlQX+0/1OdRA	false	glutathione s tranferase tag:?-?(MINT-7979020)	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:P30822	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979811|mint:MINT-7978992|imex:IM-15065-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7979003(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7978994(identity)	-	crc64:C9D027033F8C70E1	crc64:A81833C7F60F5202	figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:39A5FDC4FAD4E5CF|rigid:mh1XRGwAehK5jG62awOhYCs3sPw	false	glutathione s tranferase tag:?-?(MINT-7979004)	binding-associated region:413-1084,1-377(MINT-7978995)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P32835	uniprotkb:P41920	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-29523|uniprotkb:D6VRY9|ensemblfungi:YDR002W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:yrb1_yeast(display_long)|uniprotkb:CST20(gene name synonym)|uniprotkb:YRB1(gene name)|psi-mi:YRB1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)|uniprotkb:Perinuclear array-localized protein(gene name synonym)|uniprotkb:Chromosome stability protein 20(gene name synonym)|uniprotkb:HTN1(gene name synonym)|uniprotkb:SFO1(gene name synonym)|uniprotkb:YDR002W(locus name)|uniprotkb:YD8119.08(orf name)	psi-mi:"MI:0096"(pull down)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979811|mint:MINT-7978992|imex:IM-15065-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7979003(identity)	refseq:NP_010285.1|sgd:S000002409|dip:DIP-838N|ensemblfungi:YDR002W(gene)|ensemblfungi:YDR002W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3M1I|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4WVF|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|mint:MINT-7978999(identity)	-	crc64:C9D027033F8C70E1	crc64:46C3766B0906A75B	figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:my2AY/L5hSkeYhsyWGTQA3s27Ak559292	intact-crc:39A5FDC4FAD4E5CF|rigid:mh1XRGwAehK5jG62awOhYCs3sPw	false	glutathione s tranferase tag:?-?(MINT-7979004)	binding-associated region:11-201(MINT-7979009)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979892|mint:MINT-7950099|imex:IM-15065-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950109(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950101(identity)	-	crc64:A81833C7F60F5202	-	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:f1d t1 f7a f7c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:136.98(second)	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:95315DDB1699FB63|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	cyan fluorescent protein tag:?-?(MINT-7950110)	yellow fluorescent protein tag:?-?(MINT-7950104)|binding-associated region:38-47(MINT-7950106)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979866|mint:MINT-7950070|imex:IM-15065-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950072(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950084(identity)	-	-	crc64:A81833C7F60F5202	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:E4EEF0183205A8CB|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	mutation disrupting interaction:47-47(MINT-7950075)|binding-associated region:38-47(MINT-7950090)|yellow fluorescent protein tag:?-?(MINT-7950081)	cyan fluorescent protein tag:?-?(MINT-7950096)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979916|mint:MINT-7950122|imex:IM-15065-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950125(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950131(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|figure legend:f1e t1|comment:in presence of yeast RanGAP and yeast RanBP1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:0.064(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:844F8404B8A952E3|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950128)|binding-associated region:38-47(MINT-7950126)	cyan fluorescent protein tag:?-?(MINT-7950132)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979957|mint:MINT-7950141|imex:IM-15065-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950150(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950144(identity)	-	crc64:A81833C7F60F5202	-	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:t1 sf3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:76.92(second)	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:81B7B8811E69F51F|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	binding-associated region:1-377,413-1084(MINT-7950156)|cyan fluorescent protein tag:?-?(MINT-7950151)	binding-associated region:38-47(MINT-7950147)|yellow fluorescent protein tag:?-?(MINT-7950145)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7979985|mint:MINT-7950160|imex:IM-15065-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950169(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950163(identity)	-	crc64:A81833C7F60F5202	-	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:t1 f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:100.0(second)	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:B96F07B32D13302B|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	mutation increasing interaction:441-441(MINT-7950177)|cyan fluorescent protein tag:?-?(MINT-7950173)	binding-associated region:38-47(MINT-7950164)|yellow fluorescent protein tag:?-?(MINT-7950166)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980013|mint:MINT-7950200|imex:IM-15065-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950209(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950203(identity)	-	crc64:A81833C7F60F5202	-	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:t1 f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:71.42(second)	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:00F7D7CA530203DB|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	cyan fluorescent protein tag:?-?(MINT-7950221)|mutation increasing interaction:441-442(MINT-7950210)	yellow fluorescent protein tag:?-?(MINT-7950204)|binding-associated region:38-47(MINT-7950206)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980073|mint:MINT-7950269|imex:IM-15065-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950272(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950278(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:t1 f6d f7b f7d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:90.9(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:AC6DE8ABCCEF151C|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950273)|binding-associated region:38-47(MINT-7950275)	mutation increasing interaction:754-754(MINT-7950279)|cyan fluorescent protein tag:?-?(MINT-7950281)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980045|mint:MINT-7950225|imex:IM-15065-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950228(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950234(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP.|figure legend:t1 f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:111.11(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:BB57DF4859E87FA5|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	binding-associated region:38-47(MINT-7950229)|yellow fluorescent protein tag:?-?(MINT-7950231)	cyan fluorescent protein tag:?-?(MINT-7950235)|mutation increasing interaction:443-443(MINT-7950239)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980125|mint:MINT-7950762|imex:IM-15065-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950765(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950771(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP and RanBP1.|figure legend:t1 f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.47(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:FAD7B4BF837F3678|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950766)|binding-associated region:38-47(MINT-7950768)	mutation increasing interaction:441-441(MINT-7950772)|cyan fluorescent protein tag:?-?(MINT-7950774)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:O14980	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980101|mint:MINT-7950372|imex:IM-15065-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950375(identity)	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N|mint:MINT-7950381(identity)	-	-	-	figure legend:t1|comment:homomint|comment:mint|comment:in presence of canine RanGAP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:181.81(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:406E968F305C9DBA|rigid:P47ITUS4oqZXOjykqOYtIEEsMio	false	binding-associated region:38-47(MINT-7950378)|yellow fluorescent protein tag:?-?(MINT-7950376)	cyan fluorescent protein tag:?-?(MINT-7950384)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30822	uniprotkb:P61925	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980170|mint:MINT-7950746|imex:IM-15065-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950755(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950749(identity)	-	crc64:A81833C7F60F5202	-	comment:homomint|comment:mint|comment:"in presence of yeast RanGAP and RanBP1 (aa 11-201)."|figure legend:t1 sf3d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:0.033(second)	2010/07/05	2014/10/16	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:80889C6414CAFCF7|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	cyan fluorescent protein tag:?-?(MINT-7950759)|binding-associated region:1-377,413-1084(MINT-7950756)	yellow fluorescent protein tag:?-?(MINT-7950752)|binding-associated region:38-47(MINT-7950750)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980198|mint:MINT-7950778|imex:IM-15065-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950782(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950788(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP and RanBP1.|figure legend:t1 f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:1.99(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:D9FD44767D507B01|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950785)|binding-associated region:38-47(MINT-7950783)	mutation increasing interaction:441-442(MINT-7950793)|cyan fluorescent protein tag:?-?(MINT-7950789)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980259|mint:MINT-7950799|imex:IM-15065-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950814(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950820(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP and RanBP1.|figure legend:t1 f6e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:0.074(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:881398466F287064|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950817)|binding-associated region:38-47(MINT-7950815)	cyan fluorescent protein tag:?-?(MINT-7950821)|mutation increasing interaction:754-754(MINT-7950823)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14980	uniprotkb:P61925	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980330|mint:MINT-7950829|imex:IM-15065-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N|mint:MINT-7950838(identity)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950832(identity)	-	-	-	figure legend:t1|comment:homomint|comment:mint|comment:in presence of yeast RanGAP and Human RanBP1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:0.39(second)	2010/07/05	2014/10/16	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	intact-crc:1A302A896217450A|rigid:P47ITUS4oqZXOjykqOYtIEEsMio	false	cyan fluorescent protein tag:?-?(MINT-7950839)	yellow fluorescent protein tag:?-?(MINT-7950835)|binding-associated region:38-47(MINT-7950833)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61925	uniprotkb:P30822	intact:EBI-2682139|uniprotkb:Q6IAV2|uniprotkb:P04541|ensembl:ENSP00000336552|ensembl:ENSP00000379696|ensembl:ENSP00000430887	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:ipka_human(display_long)|uniprotkb:PRKACN1(gene name synonym)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym)|uniprotkb:PKIA(gene name)|psi-mi:PKIA(display_short)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980287|mint:MINT-7950796|imex:IM-15065-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006814.1|refseq:NP_862822.1|ensembl:ENSG00000171033(gene)|ensembl:ENST00000352966(transcript)|ensembl:ENST00000396418(transcript)|ensembl:ENST00000518467(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|rcsb pdb:1CMK|rcsb pdb:1JLU|rcsb pdb:1Q8T|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:3WYG|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4AXA|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:4Z83|rcsb pdb:4Z84|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5DH9|rcsb pdb:5LCP|rcsb pdb:5LCQ|rcsb pdb:5LCR|rcsb pdb:5LCT|rcsb pdb:5LCU|rcsb pdb:5M0B|rcsb pdb:5M0C|rcsb pdb:5M0L|rcsb pdb:5M0U|rcsb pdb:5M6V|rcsb pdb:5M6Y|rcsb pdb:5M71|rcsb pdb:5M75|rcsb pdb:5N23|rcsb pdb:5XOJ|rcsb pdb:6E21|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:6FRX|rcsb pdb:6QJ7|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:1YDR|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2GNI|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2L1L|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:2UW4|refseq:XP_016869109.1|refseq:XP_016869110.1|refseq:XP_016869111.1|dip:DIP-56176N|mint:MINT-7950800(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950806(identity)	-	-	crc64:A81833C7F60F5202	comment:homomint|comment:mint|comment:in presence of yeast RanGAP and RanBP1.|figure legend:t1 f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.33(second)	2010/07/05	2014/10/16	rogid:6HSFmAlGW02D7RfE9Iws5KvwYIk9606	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:885DA88AC35D206F|rigid:74JM/icYXG7xk3EZaeKjF0KD39s	false	yellow fluorescent protein tag:?-?(MINT-7950801)|binding-associated region:38-47(MINT-7950803)	mutation increasing interaction:443-443(MINT-7950809)|cyan fluorescent protein tag:?-?(MINT-7950807)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32835	uniprotkb:P30822	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980434|mint:MINT-7950895|imex:IM-15065-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7950897(identity)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822|mint:MINT-7950899(identity)	-	crc64:C9D027033F8C70E1	crc64:A81833C7F60F5202	comment:homomint|comment:mint|figure legend:t2 f2 f3a f4 f6a sf9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	intact-crc:96D7D99160DCF701|rigid:mh1XRGwAehK5jG62awOhYCs3sPw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32835	uniprotkb:P41920	intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C	intact:EBI-29523|uniprotkb:D6VRY9|ensemblfungi:YDR002W	psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym)	psi-mi:yrb1_yeast(display_long)|uniprotkb:CST20(gene name synonym)|uniprotkb:YRB1(gene name)|psi-mi:YRB1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)|uniprotkb:Perinuclear array-localized protein(gene name synonym)|uniprotkb:Chromosome stability protein 20(gene name synonym)|uniprotkb:HTN1(gene name synonym)|uniprotkb:SFO1(gene name synonym)|uniprotkb:YDR002W(locus name)|uniprotkb:YD8119.08(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Koyama et al. (2010)	pubmed:20485264|imex:IM-15065|mint:MINT-7950037|doi:10.1038/emboj.2010.89	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7980434|mint:MINT-7950895|imex:IM-15065-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933|mint:MINT-7950897(identity)	refseq:NP_010285.1|sgd:S000002409|dip:DIP-838N|ensemblfungi:YDR002W(gene)|ensemblfungi:YDR002W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3M1I|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4WVF|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|mint:MINT-7950898(identity)	-	crc64:C9D027033F8C70E1	crc64:46C3766B0906A75B	comment:homomint|comment:mint|figure legend:t2 f2 f3a f4 f6a sf9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292	rogid:my2AY/L5hSkeYhsyWGTQA3s27Ak559292	intact-crc:96D7D99160DCF701|rigid:mh1XRGwAehK5jG62awOhYCs3sPw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)