#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WHU1 uniprotkb:P9WHT9 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Li et al. (2010) pubmed:20461058|imex:IM-15044|mint:MINT-7985903|doi:10.1038/emboj.2010.95 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7947996|mint:MINT-7986024|imex:IM-15044-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7986028(identity) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7986026(identity) - crc64:0356FED74869998A|comment:mint|comment:"Stoichiometry: 14.14" crc64:3FC3FCD81231E129|comment:mint|comment:"Stoichiometry: 14.14" comment:mint|figure legend:f3a f3b f4a f4b f4c f5a f5b f5c f5d st1 sf4a sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/26 2022/01/21 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 intact-crc:AA104EDA91F538CD|rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false - - 14 14 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WHT9 uniprotkb:P9WHU1 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Li et al. (2010) pubmed:20461058|imex:IM-15044|mint:MINT-7985903|doi:10.1038/emboj.2010.95 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7948143|mint:MINT-7985973|imex:IM-15044-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7985976(identity) rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7985975(identity) - crc64:3FC3FCD81231E129|comment:mint|comment:"Stoichiometry: 14.14" crc64:0356FED74869998A|comment:mint|comment:"Stoichiometry: 14.14" comment:mint|figure legend:f2 sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/26 2022/01/21 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 intact-crc:3BAE309FDB86F72D|rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false - - 14 14 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WHT9 uniprotkb:P9WHU1 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Li et al. (2010) pubmed:20461058|imex:IM-15044|mint:MINT-7985903|doi:10.1038/emboj.2010.95 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7948157|mint:MINT-7985985|imex:IM-15044-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7985989(identity) rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE|mint:MINT-7985987(identity) - crc64:3FC3FCD81231E129|comment:mint|comment:"Stoichiometry: 7.7" crc64:0356FED74869998A|comment:mint|comment:"Stoichiometry: 7.7" comment:mint|figure legend:f1 sf1c sf1d sf1e sf1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/26 2022/01/21 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 intact-crc:ADFC38A95B8E3A9C|rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false - - 7 7 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)