#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9JKX8 uniprotkb:G1TDF6 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-7947305|intact:MINT-7949275|ensembl:ENSOCUP00000014873 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:g1tdf6_rabit(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Khandelwal et al. (2010) pubmed:20461056|imex:IM-15111|mint:MINT-7943934|doi:10.1038/emboj.2010.91 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7947298|mint:MINT-7943945|imex:IM-15111-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation)|mint:MINT-7943947(identity) refseq:XP_002714406.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042383"(sarcolemma)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|ensembl:ENSOCUG00000017308(gene)|ensembl:ENSOCUT00000017309(transcript)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008180"(COP9 signalosome)|mint:MINT-7943948(identity) go:"GO:0016324"(apical plasma membrane) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" comment:mint figure legend:f5c|comment:mint|comment:"UP3a has been detected endougenously expressed in Oryctolagus cuniculus (9986) cells by using an antibody raised against the mouse isoform, since the rabbit accession number has not been updated we have inferred its accession number to the mouse ID."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/30 2014/10/16 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:9yjjyUS/eyQ6MABh7a2PFI6VzUw9986 intact-crc:AB9F679CA0D171FB|rigid:AhQzYD1FhPqHTqzr8P7BUUpmW/o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)