#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28574 uniprotkb:P01108 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-1183114|uniprotkb:P70247|uniprotkb:Q3UM70|uniprotkb:Q61422|ensembl:ENSMUSP00000123821|ensembl:ENSMUSP00000123852|ensembl:ENSMUSP00000124758 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:myc_mouse(display_long)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2654959|imex:IM-14949-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N refseq:NP_001170823.1|refseq:NP_001170824.1|refseq:NP_001170825.1|ensembl:ENSMUSG00000022346(gene)|ensembl:ENSMUST00000159327(transcript)|ensembl:ENSMUST00000160009(transcript)|ensembl:ENSMUST00000161976(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006848"(pyruvate transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009314"(response to radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016485"(protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043473"(pigmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044337"(canonical Wnt signaling pathway involved in positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046722"(lactic acid secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-MMU-5689880|reactome:R-MMU-8866911|reactome:R-MMU-9018519|dip:DIP-1064N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2018/06/01 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:nmDkyD4dlB5zKDpuzjv+JEpHZS410090 intact-crc:5142AC0A6DE031C0|rigid:ECfgeJZo7Yn0fQOKFoFtNaZD77A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28574 uniprotkb:Q99J95 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655004|imex:IM-14949-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2018/06/01 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 intact-crc:B36E463D1DC4C3A5|rigid:y0DkRsCsRudjnpvCYlLOamoXyMY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28574 uniprotkb:Q9QWV9 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-2655009|uniprotkb:Q9Z0U7|uniprotkb:Q3V0G4|ensembl:ENSMUSP00000012104|ensembl:ENSMUSP00000126874 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:ccnt1_mouse(display_long)|uniprotkb:Ccnt1(gene name)|psi-mi:Ccnt1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655029|imex:IM-14949-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N refseq:NP_033963.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:Q9QWV9|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|ensembl:ENSMUSG00000011960(gene)|ensembl:ENSMUST00000012104(transcript)|ensembl:ENSMUST00000169707(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2018/06/01 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:0OHMWIM5Vb9/Whq5PdvunZdi1F010090 intact-crc:331750C4BF3E170C|rigid:uh7aA1PoVj3Mc05ZqwUmtkvWOL8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:P01108 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-1183114|uniprotkb:P70247|uniprotkb:Q3UM70|uniprotkb:Q61422|ensembl:ENSMUSP00000123821|ensembl:ENSMUSP00000123852|ensembl:ENSMUSP00000124758 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:myc_mouse(display_long)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655036|imex:IM-14949-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001170823.1|refseq:NP_001170824.1|refseq:NP_001170825.1|ensembl:ENSMUSG00000022346(gene)|ensembl:ENSMUST00000159327(transcript)|ensembl:ENSMUST00000160009(transcript)|ensembl:ENSMUST00000161976(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006848"(pyruvate transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009314"(response to radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016485"(protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043473"(pigmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044337"(canonical Wnt signaling pathway involved in positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046722"(lactic acid secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-MMU-5689880|reactome:R-MMU-8866911|reactome:R-MMU-9018519|dip:DIP-1064N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:nmDkyD4dlB5zKDpuzjv+JEpHZS410090 intact-crc:7397537A2A11C166|rigid:MS1+3tyeb3tPEakORAAuLfv0TXU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28574 uniprotkb:Q99J95 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655041|imex:IM-14949-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2018/06/01 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 intact-crc:B4CFE14EFC9830E9|rigid:y0DkRsCsRudjnpvCYlLOamoXyMY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P01108 uniprotkb:Q9QWV9 intact:EBI-1183114|uniprotkb:P70247|uniprotkb:Q3UM70|uniprotkb:Q61422|ensembl:ENSMUSP00000123821|ensembl:ENSMUSP00000123852|ensembl:ENSMUSP00000124758 intact:EBI-2655009|uniprotkb:Q9Z0U7|uniprotkb:Q3V0G4|ensembl:ENSMUSP00000012104|ensembl:ENSMUSP00000126874 psi-mi:myc_mouse(display_long)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short) psi-mi:ccnt1_mouse(display_long)|uniprotkb:Ccnt1(gene name)|psi-mi:Ccnt1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655046|imex:IM-14949-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170823.1|refseq:NP_001170824.1|refseq:NP_001170825.1|ensembl:ENSMUSG00000022346(gene)|ensembl:ENSMUST00000159327(transcript)|ensembl:ENSMUST00000160009(transcript)|ensembl:ENSMUST00000161976(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006848"(pyruvate transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009314"(response to radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016485"(protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043473"(pigmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044337"(canonical Wnt signaling pathway involved in positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046722"(lactic acid secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-MMU-5689880|reactome:R-MMU-8866911|reactome:R-MMU-9018519|dip:DIP-1064N refseq:NP_033963.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:Q9QWV9|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|ensembl:ENSMUSG00000011960(gene)|ensembl:ENSMUST00000012104(transcript)|ensembl:ENSMUST00000169707(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2014/10/16 rogid:nmDkyD4dlB5zKDpuzjv+JEpHZS410090 rogid:0OHMWIM5Vb9/Whq5PdvunZdi1F010090 intact-crc:F3EE458388EB15CF|rigid:tEXvpBXw7SQpQvvJwGy0s3gTSaI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28574 uniprotkb:Q9QWV9 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-2655009|uniprotkb:Q9Z0U7|uniprotkb:Q3V0G4|ensembl:ENSMUSP00000012104|ensembl:ENSMUSP00000126874 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:ccnt1_mouse(display_long)|uniprotkb:Ccnt1(gene name)|psi-mi:Ccnt1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rahl et al. (2010) imex:IM-14949|pubmed:20434984 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2655051|imex:IM-14949-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N refseq:NP_033963.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:Q9QWV9|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|ensembl:ENSMUSG00000011960(gene)|ensembl:ENSMUST00000012104(transcript)|ensembl:ENSMUST00000169707(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/05/06 2018/06/01 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:0OHMWIM5Vb9/Whq5PdvunZdi1F010090 intact-crc:C0021469424CAC60|rigid:uh7aA1PoVj3Mc05ZqwUmtkvWOL8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)