#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q03067	uniprotkb:P53165	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677283|wwpdb:3M99|imex:IM-14705-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	-	crc64:31CBBD4CAA18F3F9	crc64:4618E2E47824321D	figure legend:Supp. Table 1|3d-resolution:2.7A|3d-r-factors:"R-factor: 23.7%, Free R-factor: 30.0%,"|3d-structure:Two functional lobes are structurally coupled by Sgf73. In the assembly lobe, a long Sgf11 N-terminal helix is clamped onto the Ubp8 ZnF-UBP domain by Sus1. In the catalytic lobe, an Sgf11 C-terminal zinc-finger domain binds to the Ubp8 catalytic domain next to its active site.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	intact-crc:930E3F873FBC9783|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	-	sufficient binding region:1-104	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:Q6WNK7	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677283|wwpdb:3M99|imex:IM-14705-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	-	crc64:31CBBD4CAA18F3F9	crc64:DB0DA0C9DC13FB21	figure legend:Supp. Table 1|3d-resolution:2.7A|3d-r-factors:"R-factor: 23.7%, Free R-factor: 30.0%,"|3d-structure:Two functional lobes are structurally coupled by Sgf73. In the assembly lobe, a long Sgf11 N-terminal helix is clamped onto the Ubp8 ZnF-UBP domain by Sus1. In the catalytic lobe, an Sgf11 C-terminal zinc-finger domain binds to the Ubp8 catalytic domain next to its active site.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:930E3F873FBC9783|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P50102	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677283|wwpdb:3M99|imex:IM-14705-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	-	crc64:31CBBD4CAA18F3F9	crc64:BC632F12FBD0F73C	figure legend:Supp. Table 1|3d-resolution:2.7A|3d-r-factors:"R-factor: 23.7%, Free R-factor: 30.0%,"|3d-structure:Two functional lobes are structurally coupled by Sgf73. In the assembly lobe, a long Sgf11 N-terminal helix is clamped onto the Ubp8 ZnF-UBP domain by Sus1. In the catalytic lobe, an Sgf11 C-terminal zinc-finger domain binds to the Ubp8 catalytic domain next to its active site.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:930E3F873FBC9783|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:Q6WNK7	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677301|imex:IM-14705-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:DB0DA0C9DC13FB21	figure legend:Fig. 2G, 5A, 5B, 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:2EF22CBEDA124061|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	glutathione s tranferase tag:?-?	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03067	uniprotkb:P50102	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677301|imex:IM-14705-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:BC632F12FBD0F73C	figure legend:Fig. 2G, 5A, 5B, 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:2EF22CBEDA124061|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	glutathione s tranferase tag:?-?	necessary binding region:83-107	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03067	uniprotkb:P53165	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677301|imex:IM-14705-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:4618E2E47824321D	figure legend:Fig. 2G, 5A, 5B, 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	intact-crc:2EF22CBEDA124061|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	glutathione s tranferase tag:?-?	sufficient binding region:1-104|his tag:?-?	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53165	uniprotkb:Q03067	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677319|imex:IM-14705-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:4618E2E47824321D	crc64:31CBBD4CAA18F3F9	figure legend:Fig. 2G. 6F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	intact-crc:BB13292113FD520C|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	sufficient binding region:1-104|his tag:?-?	glutathione s tranferase tag:?-?	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53165	uniprotkb:P50102	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677319|imex:IM-14705-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	psi-mi:"MI:0469"(intact)	crc64:4618E2E47824321D	crc64:BC632F12FBD0F73C	figure legend:Fig. 2G. 6F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:BB13292113FD520C|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	sufficient binding region:1-104|his tag:?-?	necessary binding region:83-107	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53165	uniprotkb:Q6WNK7	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677319|imex:IM-14705-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	psi-mi:"MI:0469"(intact)	crc64:4618E2E47824321D	crc64:DB0DA0C9DC13FB21	figure legend:Fig. 2G. 6F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:BB13292113FD520C|rigid:hz40Q50WZX9hiHZvDgbK0Yj8FQM	false	sufficient binding region:1-104|his tag:?-?	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50102	uniprotkb:Q03067	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677334|imex:IM-14705-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:BC632F12FBD0F73C	crc64:31CBBD4CAA18F3F9	figure legend:Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	intact-crc:AD7165D506D00BC1|rigid:cAAkKyj4MhCYJKa627NA14Ucuhc	false	necessary binding region:1-107	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50102	uniprotkb:Q6WNK7	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677334|imex:IM-14705-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	psi-mi:"MI:0469"(intact)	crc64:BC632F12FBD0F73C	crc64:DB0DA0C9DC13FB21	figure legend:Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:AD7165D506D00BC1|rigid:cAAkKyj4MhCYJKa627NA14Ucuhc	false	necessary binding region:1-107	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03067	uniprotkb:P53165	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677401|imex:IM-14705-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:4618E2E47824321D	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	intact-crc:D168A68414F4D65F|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?|necessary binding region:1-44|mutation decreasing interaction rate:86-86|mutation disrupting interaction rate:89-89,86-86|mutation disrupting interaction rate:85-85|mutation disrupting interaction rate:89-89	his tag:?-?|sufficient binding region:1-104	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:Q6WNK7	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677401|imex:IM-14705-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:DB0DA0C9DC13FB21	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:D168A68414F4D65F|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?|necessary binding region:1-44|mutation decreasing interaction rate:86-86|mutation disrupting interaction rate:89-89,86-86|mutation disrupting interaction rate:85-85|mutation disrupting interaction rate:89-89	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P0CG47	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677401|imex:IM-14705-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	-	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:D168A68414F4D65F|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?|necessary binding region:1-44|mutation decreasing interaction rate:86-86|mutation disrupting interaction rate:89-89,86-86|mutation disrupting interaction rate:85-85|mutation disrupting interaction rate:89-89	tag:c-c	1	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P50102	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2677401|imex:IM-14705-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:BC632F12FBD0F73C	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:D168A68414F4D65F|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?|necessary binding region:1-44|mutation decreasing interaction rate:86-86|mutation disrupting interaction rate:89-89,86-86|mutation disrupting interaction rate:85-85|mutation disrupting interaction rate:89-89	necessary binding region:83-107	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P53165	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678523|imex:IM-14705-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:4618E2E47824321D	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	intact-crc:A61577A8F4950B79|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?	his tag:?-?|necessary binding region:90-104|mutation:93-93	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:Q6WNK7	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678523|imex:IM-14705-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene)	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:DB0DA0C9DC13FB21	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292	intact-crc:A61577A8F4950B79|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P0CG47	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678523|imex:IM-14705-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	-	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:A61577A8F4950B79|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?	tag:c-c	1	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03067	uniprotkb:P50102	intact:EBI-34550|uniprotkb:D6W3W7|ensemblfungi:YPL047W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:sgf11_yeast(display_long)|uniprotkb:SGF11(gene name)|psi-mi:SGF11(display_short)|uniprotkb:11 kDa SAGA-associated factor(gene name synonym)|uniprotkb:YPL047W(locus name)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678523|imex:IM-14705-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015278.1|sgd:S000005968|mint:Q03067|dip:DIP-39582N|ensemblfungi:YPL047W(gene)|ensemblfungi:YPL047W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0071819"(DUBm complex)|interpro:IPR013246(Sgf11, transcriptional regulation)|interpro:IPR041216|rcsb pdb:2LO2|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	psi-mi:"MI:0469"(intact)	crc64:31CBBD4CAA18F3F9	crc64:BC632F12FBD0F73C	figure legend:Fig. 5A. 5B|comment:Mutations alter the rate of ubiquitin carboxyl-terminal hydrolase activity but not the formation of the tetrameric complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/24	2014/10/16	rogid:D1rjYNXMK75P1lJxeQ8oBjl0n+w559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:A61577A8F4950B79|rigid:BuxOtVR6CHTXboDii9ggXP+PORU	false	glutathione s tranferase tag:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02336	uniprotkb:P35177	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-17958|uniprotkb:D6VQ80|ensemblfungi:YBR081C	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:spt7_yeast(display_long)|uniprotkb:YBR0739(orf name)|uniprotkb:YBR081C(locus name)|uniprotkb:SPT7(gene name)|psi-mi:SPT7(display_short)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_009637.1|sgd:S000000285|ensemblfungi:YBR081C(gene)|ensemblfungi:YBR081C_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0034622"|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009072(Histone-fold)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037782|rcsb pdb:6T9I|rcsb pdb:6T9K|dip:DIP-771N|mint:P35177	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:083B63624669244F	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:U3k+xA1SuVJRX240wH99s5ijrN0559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q02336	uniprotkb:P38811	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-24638|uniprotkb:D3DL49|ensemblfungi:YHR099W	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:tra1_yeast(display_long)|uniprotkb:TRA1(gene name)|psi-mi:TRA1(display_short)|uniprotkb:p400 kDa component of SAGA(gene name synonym)|uniprotkb:YHR099W(locus name)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_011967.1|sgd:S000001141|dip:DIP-805N|mint:P38811|ensemblfungi:YHR099W(gene)|ensemblfungi:YHR099W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016301"(kinase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070209"(ASTRA complex)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|interpro:IPR036940|rcsb pdb:5OJS|rcsb pdb:6IG9|rcsb pdb:6T9I|rcsb pdb:6T9J	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:AE3588676F5D5777	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:B/rkvJoIvK1Xi2SoNtFnFOdcp2c559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q02336	uniprotkb:P06844	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-17921|uniprotkb:Q70DE7|uniprotkb:Q70DE9|uniprotkb:Q70DF1|uniprotkb:Q70DF2|uniprotkb:D6VT26|ensemblfungi:YDR392W	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:spt3_yeast(display_long)|uniprotkb:SPT3(gene name)|psi-mi:SPT3(display_short)|uniprotkb:YDR392W(locus name)|uniprotkb:D9509.12(orf name)|uniprotkb:Positive regulator of Ty transcription(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_010680.1|sgd:S000002800|ensemblfungi:YDR392W(gene)|ensemblfungi:YDR392W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016573"(histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|rcsb pdb:6T9I|rcsb pdb:6T9K|dip:DIP-2204N|mint:P06844	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:E0F60B61AB155C17	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:uSJbqSttGDguBvx/e2mgMB2tiio559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q02336	uniprotkb:Q03330	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-7458|uniprotkb:Q6B165|uniprotkb:D6VV32|ensemblfungi:YGR252W	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:gcn5_yeast(display_long)|uniprotkb:YGR252W(locus name)|uniprotkb:GCN5(gene name)|psi-mi:GCN5(display_short)|uniprotkb:ADA4(gene name synonym)|uniprotkb:SWI9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_011768.1|sgd:S000003484|mint:Q03330|dip:DIP-710N|ensemblfungi:YGR252W(gene)|ensemblfungi:YGR252W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0140068"(histone crotonyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|rcsb pdb:1E6I|rcsb pdb:1YGH|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880|reactome:R-SCE-9018519	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:3200730DDC7EF70D	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:Y8SHidiW4dJo0oxEDksur8MC/L0559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q02336	uniprotkb:P50102	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-19863|uniprotkb:D6W048|ensemblfungi:YMR223W	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:ubp8_yeast(display_long)|uniprotkb:UBP8(gene name)|psi-mi:UBP8(display_short)|uniprotkb:YMR223W(locus name)|uniprotkb:YM9959.05(orf name)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_013950.1|sgd:S000004836|ensemblfungi:YMR223W(gene)|ensemblfungi:YMR223W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071819"(DUBm complex)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR037798|interpro:IPR038765|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|reactome:R-SCE-5689880|dip:DIP-1506N|mint:P50102	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:BC632F12FBD0F73C	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:7vOj35ZOWGzKXD97FlZTEImy3NE559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q02336	uniprotkb:P53165	intact:EBI-2186|uniprotkb:D6VT73|ensemblfungi:YDR448W	intact:EBI-23812|uniprotkb:D6VU75|ensemblfungi:YGL066W	psi-mi:ada2_yeast(display_long)|uniprotkb:ADA2(gene name)|psi-mi:ADA2(display_short)|uniprotkb:D9461.33(orf name)|uniprotkb:YDR448W(locus name)	psi-mi:sgf73_yeast(display_long)|uniprotkb:YGL066W(locus name)|uniprotkb:SGF73(gene name)|psi-mi:SGF73(display_short)|uniprotkb:73 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 73 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kohler et al. (2010)	imex:IM-14705|pubmed:20434206	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2678561|imex:IM-14705-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002856|refseq:NP_010736.3|dip:DIP-183N|mint:Q02336|ensemblfungi:YDR448W(gene)|ensemblfungi:YDR448W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070461"(SAGA-type complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|rcsb pdb:2ELJ|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880	refseq:NP_011449.1|sgd:S000003034|dip:DIP-5211N|mint:P53165|ensemblfungi:YGL066W(gene)|ensemblfungi:YGL066W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0034622"|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071819"(DUBm complex)|go:"GO:1904802"(RITS complex assembly)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR013243(SCA7)|interpro:IPR037804|interpro:IPR041251|rcsb pdb:2LO3|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:3MHS|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4W4U|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9I|rcsb pdb:6T9K|rcsb pdb:6T9L	psi-mi:"MI:0469"(intact)	crc64:9637E1EDBBED0AC3	crc64:4618E2E47824321D	figure legend:Supp. Fig. 4B|comment:The sgf73 W32A/K33A/H93A mutant and deletion mutant lacking residues 1-104  both failed to bind UBP8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/05/24	2014/10/16	rogid:Yz+0dWGKNP6/ELscgW0yuQk/EyY559292	rogid:lHCTTSpU/OTcY8Uo7BtHqRbZL38559292	intact-crc:55AD1C8C7CE1C8DA|rigid:KyMJ9AAZZON/WZhApV5hefATg0o	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)