#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75943 uniprotkb:Q99638 intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5 intact:EBI-2606224|uniprotkb:B2RCZ8|uniprotkb:Q6FI29|uniprotkb:Q96C41|ensembl:ENSP00000311360 psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym) psi-mi:rad9a_human(display_long)|uniprotkb:DNA repair exonuclease rad9 homolog A(gene name synonym)|uniprotkb:RAD9A(gene name)|psi-mi:RAD9A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932393|mint:MINT-7897390|imex:IM-15110-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N|mint:MINT-7897392(identity) refseq:NP_004575.1|ensembl:ENSG00000172613(gene)|ensembl:ENST00000307980(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR007268(Rad9)|interpro:IPR026584|mint:Q99638|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6HM5|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001230153.1|dip:DIP-24255N|dip:DIP-40930N|mint:MINT-7897393(identity) - - - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606 rogid:W32q7Paqhs+FCM3bCprDXrqlG449606 intact-crc:C480408EFE436656|rigid:KcYWMA/kA0C6SMeDP54OnmJYSho false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9XT62 uniprotkb:Q99638 intact:EBI-7932422|intact:MINT-7897435 intact:EBI-2606224|uniprotkb:B2RCZ8|uniprotkb:Q6FI29|uniprotkb:Q96C41|ensembl:ENSP00000311360 psi-mi:rad17_chlae(display_long)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short) psi-mi:rad9a_human(display_long)|uniprotkb:DNA repair exonuclease rad9 homolog A(gene name synonym)|uniprotkb:RAD9A(gene name)|psi-mi:RAD9A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932435|mint:MINT-7897420|imex:IM-15110-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018324|interpro:IPR027417|interpro:IPR004582(Checkpoint protein Rad24)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0031389"(Rad17 RFC-like complex)|mint:Q9XT62|mint:MINT-7897422(identity) refseq:NP_004575.1|ensembl:ENSG00000172613(gene)|ensembl:ENST00000307980(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR007268(Rad9)|interpro:IPR026584|mint:Q99638|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6HM5|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001230153.1|dip:DIP-24255N|dip:DIP-40930N|mint:MINT-7897424(identity) - comment:mint - comment:mint|figure legend:f6a f6b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:m6hI3Y9KRG5VVjOBud1gMXvha749534 rogid:W32q7Paqhs+FCM3bCprDXrqlG449606 intact-crc:5A44F191515AD0A6|rigid:e1LqCGnKSzPT1G2H6C8CnngzN2c false binding-associated region:1-230,270-670(MINT-7897431)|ha tag:?-?(MINT-7897429) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99638 uniprotkb:Q9HAW4 intact:EBI-2606224|uniprotkb:B2RCZ8|uniprotkb:Q6FI29|uniprotkb:Q96C41|ensembl:ENSP00000311360 intact:EBI-1369377|uniprotkb:Q5VYG0|uniprotkb:Q6P6H5|uniprotkb:Q8IWI1|uniprotkb:A6NFL4|uniprotkb:Q1RMC6|uniprotkb:Q2KHM3|intact:EBI-28979386|ensembl:ENSP00000312995 psi-mi:rad9a_human(display_long)|uniprotkb:DNA repair exonuclease rad9 homolog A(gene name synonym)|uniprotkb:RAD9A(gene name)|psi-mi:RAD9A(display_short) psi-mi:clspn_human(display_long)|uniprotkb:CLSPN(gene name)|psi-mi:CLSPN(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932453|mint:MINT-7897445|imex:IM-15110-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004575.1|ensembl:ENSG00000172613(gene)|ensembl:ENST00000307980(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR007268(Rad9)|interpro:IPR026584|mint:Q99638|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6HM5|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001230153.1|dip:DIP-24255N|dip:DIP-40930N|mint:MINT-7897447(identity) refseq:NP_001317419.1|ensembl:ENST00000251195|ensembl:ENSP00000251195|ensembl:ENSP00000312995|ensembl:ENST00000373220|ensembl:ENSP00000362317|refseq:NP_001177410.1|refseq:NP_071394.2|ensembl:ENSG00000092853(gene)|ensembl:ENST00000318121(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|interpro:IPR024146|mint:Q9HAW4|rcsb pdb:7AKO|reactome:R-HSA-111465|reactome:R-HSA-176187|reactome:R-HSA-5689880|reactome:R-HSA-5693607|mint:MINT-7897449(identity) - - - figure legend:f7b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:W32q7Paqhs+FCM3bCprDXrqlG449606 rogid:colqtYH36pqL6fhGk1RHAf8UJVU9606 intact-crc:F0EEEBAFEA43B015|rigid:tdWOW+JPcBETOL9AU4V/09RnZ1o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75943 uniprotkb:Q9UM11 intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5 intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529 psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym) psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932479|mint:MINT-7897581|imex:IM-15110-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N|mint:MINT-7897587(identity) refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N|mint:MINT-7897583(identity) - - - figure legend:f5d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606 rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606 intact-crc:26FCCC4CE4B12524|rigid:dzvowI486vaWi5TYutSGG4yQwoE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9XT62 uniprotkb:O75943 intact:EBI-7932422|intact:MINT-7897435 intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5 psi-mi:rad17_chlae(display_long)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short) psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932465|mint:MINT-7897516|imex:IM-15110-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018324|interpro:IPR027417|interpro:IPR004582(Checkpoint protein Rad24)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0031389"(Rad17 RFC-like complex)|mint:Q9XT62|mint:MINT-7897520(identity) ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N|mint:MINT-7897518(identity) - comment:mint - figure legend:sf3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:m6hI3Y9KRG5VVjOBud1gMXvha749534 rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606 intact-crc:EBD0BE631AE8B3B0|rigid:mj98+RmMmXMi0m4fkfrh/WvSPMo false ha tag:?-?(MINT-7897524) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UM11 uniprotkb:O75943 intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529 intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5 psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym) psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932491|mint:MINT-7897592|imex:IM-15110-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N|mint:MINT-7897596(identity) ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N|mint:MINT-7897594(identity) - - - figure legend:f5d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnf)|taxid:9606(Homo sapiens) - 2010/05/31 2014/10/16 rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606 rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606 intact-crc:6F1C9849A32D5C4D|rigid:dzvowI486vaWi5TYutSGG4yQwoE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9XT62 uniprotkb:Q9UM11 intact:EBI-7932422|intact:MINT-7897435 intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529 psi-mi:rad17_chlae(display_long)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short) psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Zhang et al. (2010) pubmed:20424596|imex:IM-15110|mint:MINT-7897378|doi:10.1038/emboj.2010.55 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7932610|mint:MINT-7897528|imex:IM-15110-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018324|interpro:IPR027417|interpro:IPR004582(Checkpoint protein Rad24)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0031389"(Rad17 RFC-like complex)|mint:Q9XT62|mint:MINT-7897532(identity) refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N|mint:MINT-7897530(identity) - comment:mint - figure legend:f5c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line) - 2010/05/31 2014/10/16 rogid:m6hI3Y9KRG5VVjOBud1gMXvha749534 rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606 intact-crc:B1E6DF480B3A320E|rigid:thwByEI7iV2UYjZ7uwZ8BGFpSJY false tandem tag:?-?(MINT-7897533) - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0427"(Identification by mass spectrometry)