#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00687 uniprotkb:P24270 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924912|uniprotkb:Q3TXQ6|ensembl:ENSMUSP00000028610 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:cata_mouse(display_long)|uniprotkb:Cat(gene name)|psi-mi:Cat(display_short)|uniprotkb:Cas-1(gene name synonym)|uniprotkb:Cas1(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 go:"GO:0055093"(response to hyperoxia)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P24270|reactome:R-MMU-3299685|reactome:R-MMU-6798695|reactome:R-MMU-9033241|go:"GO:0051781"(positive regulation of cell division)|ensembl:ENSMUSG00000027187(gene)|ensembl:ENSMUST00000028610(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|refseq:NP_033934.2 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:Ahsw8/VMIQAUw7mWuBSFRn9g/3M10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P10605 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924871|ensembl:ENSMUSP00000006235|uniprotkb:Q3UDW7 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:catb_mouse(display_long)|uniprotkb:Ctsb(gene name)|psi-mi:Ctsb(display_short)|uniprotkb:Cathepsin B1(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 ensembl:ENSMUSG00000021939(gene)|ensembl:ENSMUST00000006235(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030984"(kininogen binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046697"(decidualization)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|go:"GO:0030855"(epithelial cell differentiation)|mint:P10605|reactome:R-MMU-1442490|reactome:R-MMU-1679131|reactome:R-MMU-2022090|reactome:R-MMU-2132295|reactome:R-MMU-6798695|interpro:IPR038765|refseq:NP_031824.1 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:iaXeLGV1ftr7OnUqbeLPZGpJ7NI10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q9WUU7 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924845|ensembl:ENSMUSP00000016400 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:catz_mouse(display_long)|uniprotkb:Ctsz(gene name)|psi-mi:Ctsz(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 reactome:R-MMU-6798695|reactome:R-MMU-5694530|ensembl:ENSMUSG00000016256(gene)|ensembl:ENSMUST00000016400(transcript)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0009986"(cell surface)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0099738"(cell cortex region)|go:"GO:1901214"(regulation of neuron death)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025661|interpro:IPR033157|interpro:IPR038765|mint:Q9WUU7|reactome:R-MMU-2022377|reactome:R-MMU-204005|reactome:R-MMU-432720|refseq:NP_071720.1 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:+9sKLVPwy7IrBp2HtaAoZMTuV2E10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q8C196 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2348828|uniprotkb:Q6NX75|uniprotkb:A0JNU4|ensembl:ENSMUSP00000027144 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:cpsm_mouse(display_long)|uniprotkb:Cps1(gene name)|psi-mi:Cps1(display_short)|uniprotkb:Carbamoyl-phosphate synthetase I(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 refseq:XP_011236802.1|refseq:NP_001074278.1|ensembl:ENSMUSG00000025991(gene)|ensembl:ENSMUST00000027144(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004087"("carbamoyl-phosphate synthase (ammonia) activity")|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014075"(response to amine)|go:"GO:0016595"(glutamate binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0032094"(response to food)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043200"(response to amino acid)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046209"(nitric oxide metabolic process)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0055081"(anion homeostasis)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070409"(carbamoyl phosphate biosynthetic process)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036914|mint:Q8C196|reactome:R-MMU-70635 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:rF6N6MgpvcLpTEy98xLg4/NqUCY10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P09528 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-308950|uniprotkb:Q3UI44|ensembl:ENSMUSP00000025563|ensembl:ENSMUSP00000158539 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:frih_mouse(display_long)|uniprotkb:Fth1(gene name)|psi-mi:Fth1(display_short)|uniprotkb:Fth(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 refseq:NP_034369.1|ensembl:ENSMUSG00000024661(gene)|ensembl:ENSMUST00000025563(transcript)|ensembl:ENSMUST00000235196(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|mint:P09528|rcsb pdb:3WNW|go:"GO:0008285"(negative regulation of cell population proliferation)|rcsb pdb:5OBA|go:"GO:0044754"(autolysosome)|rcsb pdb:5OBB|go:"GO:0048147"(negative regulation of fibroblast proliferation)|rcsb pdb:6S61|rcsb pdb:6SHT|rcsb pdb:6V21|rcsb pdb:7A4M|rcsb pdb:7KOD|go:"GO:0071682"(endocytic vesicle lumen)|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-917937|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site) - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:dg7aqsV02liocLxEKKesIMGxyWs10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P29391 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-309285|uniprotkb:Q8WUQ8 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:fril1_mouse(display_long)|uniprotkb:Ftl1(gene name)|psi-mi:Ftl1(display_short)|uniprotkb:Ftl(gene name synonym)|uniprotkb:Ftl-1(gene name synonym)|uniprotkb:Ferritin L subunit 1(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR014034(Ferritin, conserved site)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:1H96|rcsb pdb:1LB3|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0071682"(endocytic vesicle lumen) - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:9LMyVftFjQVCxzUakUZ7W3L5Pig10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) chebi:"CHEBI:28087" uniprotkb:P00687 intact:EBI-2507162 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long) psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 - rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q9R062 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924859|ensembl:ENSMUSP00000136035|uniprotkb:Q3TWR9 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:glyg_mouse(display_long)|uniprotkb:Gyg1(gene name)|psi-mi:Gyg1(display_short)|uniprotkb:Gyg(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 ensembl:ENSMUSG00000019528(gene)|ensembl:ENSMUST00000178328(transcript)|go:"GO:0005536"(glucose binding)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008466"(glycogenin glucosyltransferase activity)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0102751"("UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity")|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|mint:Q9R062|reactome:R-MMU-3322077|reactome:R-MMU-6798695|reactome:R-MMU-70221|refseq:NP_038783.1 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:Dpd8uSqY2t3PClX9pzZ3i87djAw10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q8VCB3 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924809|uniprotkb:Q3UTY0|ensembl:ENSMUSP00000032371 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:gys2_mouse(display_long)|uniprotkb:Gys2(gene name)|psi-mi:Gys2(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 ensembl:ENSMUSG00000030244(gene)|ensembl:ENSMUST00000032371(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043265"(ectoplasm)|interpro:IPR008631(Glycogen synthase)|mint:Q8VCB3|refseq:NP_663547.2 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:LOYPizoi8L+v8Pz2m2sY9hx5McM10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P02089 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-494213|uniprotkb:Q5D0E8 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:hbb2_mouse(display_long)|uniprotkb:Hemoglobin beta-2 chain(gene name synonym)|uniprotkb:Beta-2-globin(gene name synonym)|uniprotkb:Hemoglobin beta-minor chain(gene name synonym)|uniprotkb:Hbb-b2(gene name)|psi-mi:Hbb-b2(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|refseq:NP_058652.1|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1FNE|rcsb pdb:1FNG|rcsb pdb:1I3R|mint:P02089 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:5t7MUKklDto4E5kgtOvSP8i82vU10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P62137 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-357187|ensembl:ENSMUSP00000039109|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:Q3U7G7|uniprotkb:Q9Z1G2 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:pp1a_mouse(display_long)|uniprotkb:Ppp1ca(gene name)|psi-mi:Ppp1ca(display_short)|uniprotkb:Ppp1a(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009987"(cellular process)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62137|rcsb pdb:5ZQV|rcsb pdb:5ZT0|reactome:R-MMU-180024|ensembl:ENSMUSG00000040385(gene)|ensembl:ENSMUST00000046094(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|refseq:NP_114074.1 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:kr38FkfqhN5ex5rxh4ZJbSdd8IM10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:P24369 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-494280|ensembl:ENSMUSP00000034947 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:ppib_mouse(display_long)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Ppib(gene name)|psi-mi:Ppib(display_short)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 refseq:NP_035279.2|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0005737"(cytoplasm)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P24369|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006457"(protein folding)|reactome:R-MMU-1650814|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|ensembl:ENSMUSG00000032383(gene)|ensembl:ENSMUST00000034947(transcript) - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:Jp4wVPlfj3WNwhuh/Cvuk1TR7sY10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q8CI94 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q9ET01 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924798|uniprotkb:Q3UKJ0|ensembl:ENSMUSP00000071231 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:pygl_mouse(display_long)|uniprotkb:Pygl(gene name)|psi-mi:Pygl(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 ensembl:ENSMUSG00000021069(gene)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0019842"(vitamin binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9ET01|reactome:R-MMU-6798695|reactome:R-MMU-70221|ensembl:ENSMUST00000071250(transcript)|refseq:NP_573461.2 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:2YFwG8X0rwpFN69mD6KWCFf/vpM10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q9WUB3 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q8CE68 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2925699 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:q8ce68_mouse(display_long)|uniprotkb:Agl(gene name)|psi-mi:Agl(display_short) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 go:"GO:0004133"(glycogen debranching enzyme activity)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009725"(response to hormone)|go:"GO:0016234"(inclusion body)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0051384"(response to glucocorticoid)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR032790|mint:Q8CE68 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:WmWMcjBrpcN/n7iYhibsPXaiEB010090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00687 uniprotkb:Q8C7E7 intact:EBI-2924889|uniprotkb:Q921Y7|ensembl:ENSMUSP00000070368|ensembl:ENSMUSP00000102150 intact:EBI-2924824|ensembl:ENSMUSP00000054322|uniprotkb:Q147T8 psi-mi:amy1_mouse(display_long)|uniprotkb:Amy1(gene name)|psi-mi:Amy1(display_short)|uniprotkb:Amy-1-a(gene name synonym)|uniprotkb:Amy1a(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary and hepatic alpha-amylase(gene name synonym) psi-mi:stbd1_mouse(display_long)|uniprotkb:Stbd1(gene name)|psi-mi:Stbd1(display_short)|uniprotkb:D5Ertd593e(gene name synonym)|uniprotkb:Genethonin-1(gene name synonym)|uniprotkb:Glycophagy cargo receptor stbd1(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924771|imex:IM-20515-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074264(gene)|ensembl:ENSMUST00000067980(transcript)|ensembl:ENSMUST00000106540(transcript)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016160"(amylase activity)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-MMU-189085|interpro:IPR031319|refseq:NP_001103975.1|refseq:NP_031472.2 ensembl:ENSMUSG00000047963(gene)|ensembl:ENSMUST00000050952(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030315"(T-tubule)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR034838|mint:Q8C7E7|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423|go:"GO:0061723"(glycophagy)|refseq:NP_780305.1 - - - figure legend:Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 rogid:C4p33DZBL9PSLCAk0Pp8SdTGHfs10090 rogid:LlLqXKLm/5B/MHNATJ0yedkQ8Hk10090 intact-crc:04AE13D28EC3B87A false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P00689 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925235 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:amyp_rat(display_long)|uniprotkb:Amy2(gene name)|psi-mi:Amy2(display_short)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004556"(alpha-amylase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0031404"(chloride ion binding)|go:"GO:0103025"|rgd:1593187|refseq:NP_113690.1|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031319|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|reactome:R-RNO-189085 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:NToR0pLRktM/gtIEo7JFOWoOJuo10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P04639 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925493|ensembl:ENSRNOP00000065206|uniprotkb:O08877|uniprotkb:O09054|uniprotkb:Q5EBB2 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:apoa1_rat(display_long)|uniprotkb:Apoa1(gene name)|psi-mi:Apoa1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 reactome:R-RNO-8963901|reactome:R-RNO-8963896|reactome:R-RNO-8964011|reactome:R-RNO-8964058|reactome:R-RNO-9707616|reactome:R-RNO-975634|ensembl:ENSRNOG00000045679(gene)|ensembl:ENSRNOT00000074357(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-RNO-114608|reactome:R-RNO-1369062|reactome:R-RNO-2168880|reactome:R-RNO-3000471|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-8957275|reactome:R-RNO-8963888|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|rgd:2130|refseq:NP_036870.1|dip:DIP-29911N - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:Ms85T51VtmSYiwE+2sqnFQ6gDBU10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P02650 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-1638221|ensembl:ENSRNOP00000050968|ensembl:ENSRNOP00000068937 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:apoe_rat(display_long)|uniprotkb:Apoe(gene name)|psi-mi:Apoe(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 rgd:2138|refseq:NP_620183.2|refseq:NP_001257610.1|refseq:NP_001257611.1|refseq:NP_001257612.1|refseq:NP_001257613.1|ensembl:ENSRNOG00000018454(gene)|ensembl:ENSRNOT00000041891(transcript)|ensembl:ENSRNOT00000091574(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046848"(hydroxyapatite binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1904421"(response to D-galactosamine)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-8957275|reactome:R-RNO-8963888|reactome:R-RNO-8963901|reactome:R-RNO-8964026|reactome:R-RNO-8964058|reactome:R-RNO-975634 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:ERgpYnyTQFwZp5c5F1hi5oSwg0I10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P06761 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-916036|ensembl:ENSRNOP00000025064 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:bip_rat(display_long)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Steroidogenesis-activator polypeptide(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 rgd:2843|refseq:NP_037215.1|ensembl:ENSRNOG00000018294(gene)|ensembl:ENSRNOT00000025067(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P06761|reactome:R-RNO-3371453|reactome:R-RNO-983170 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:5HRXkoNHYJvBA2iejRqltGRdJDw10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P18418 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-916742|uniprotkb:P10452|ensembl:ENSRNOP00000004091 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:calr_rat(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:CALBP(gene name synonym)|uniprotkb:Calcium-binding protein 3(gene name synonym)|uniprotkb:Calr(gene name)|psi-mi:Calr(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 rgd:620288|refseq:NP_071794.1|ensembl:ENSRNOG00000003029(gene)|ensembl:ENSRNOT00000004091(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P18418|rcsb pdb:1HHN|rcsb pdb:1K91|rcsb pdb:1K9C|reactome:R-RNO-1236974|reactome:R-RNO-3000480|reactome:R-RNO-901042|reactome:R-RNO-983170 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:mFrLbrHGBN1Bxc+erHTyfw1NwMw10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P05179 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925298|uniprotkb:Q63706 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cp2c7_rat(display_long)|uniprotkb:Cyp2c7(gene name)|psi-mi:Cyp2c7(display_short)|uniprotkb:Cyp2c-7(gene name synonym)|uniprotkb:CYPIIC7(gene name synonym)|uniprotkb:Cytochrome P450F(gene name synonym)|uniprotkb:PTF1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008392"(arachidonic acid epoxygenase activity)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0020037"(heme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0042493"|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045471"(response to ethanol)|go:"GO:0070330"(aromatase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|rgd:620379|refseq:NP_058854.1|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR036396 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:+BnGURSq00yu/LYzB8j9IP0WtY810116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P11510 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925470 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cp2cc_rat(display_long)|uniprotkb:Cyp2c12(gene name)|psi-mi:Cyp2c12(display_short)|uniprotkb:Cyp2c-12(gene name synonym)|uniprotkb:Cyp2c40(gene name synonym)|uniprotkb:CYPIIC12(gene name synonym)|uniprotkb:Cytochrome P450I(gene name synonym)|uniprotkb:Cytochrome P450 15-beta(gene name synonym)|uniprotkb:Cytochrome P450-UT-I(gene name synonym)|uniprotkb:Cytochrome P450-UT-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008392"(arachidonic acid epoxygenase activity)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|rgd:2470|refseq:NP_113760.1|interpro:IPR036396 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:VSAY1O9gUydOdYKSrVSAo1KJR6E10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P24470 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925326|uniprotkb:Q63914|uniprotkb:Q64534 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cp2cn_rat(display_long)|uniprotkb:Cyp2c23(gene name)|psi-mi:Cyp2c23(display_short)|uniprotkb:Cyp2c-23(gene name synonym)|uniprotkb:CYPIIC23(gene name synonym)|uniprotkb:Arachidonic acid epoxygenase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008392"(arachidonic acid epoxygenase activity)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0008404"(arachidonic acid 14,15-epoxygenase activity)|go:"GO:0008405"(arachidonic acid 11,12-epoxygenase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046456"(icosanoid biosynthetic process)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0019369"(arachidonic acid metabolic process)|rgd:620370|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR036396 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:wBkaYMl6K7tv4Cy291SGc2PotEE10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P12939 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925376 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cp2da_rat(display_long)|uniprotkb:Cyp2d10(gene name)|psi-mi:Cyp2d10(display_short)|uniprotkb:Cyp2d-10(gene name synonym)|uniprotkb:Cyp2d5(gene name synonym)|uniprotkb:CYPIID10(gene name synonym)|uniprotkb:Cytochrome P450-DB5(gene name synonym)|uniprotkb:Cytochrome P450-CMF1B(gene name synonym)|uniprotkb:Debrisoquine 4-hydroxylase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|rgd:628630|refseq:NP_775426.1|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR036396 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:JAR8oYDsD66rW4AHkVTPXzgbDdQ10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P10634 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925350|ensembl:ENSRNOP00000012413 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cp2dq_rat(display_long)|uniprotkb:Cyp2d26(gene name)|psi-mi:Cyp2d26(display_short)|uniprotkb:Cyp2d-26(gene name synonym)|uniprotkb:Cyp2d2(gene name synonym)|uniprotkb:CYPIID26(gene name synonym)|uniprotkb:Cytochrome P450-DB2(gene name synonym)|uniprotkb:Cytochrome P450-CMF2(gene name synonym)|uniprotkb:Debrisoquine 4-hydroxylase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000008988(gene)|ensembl:ENSRNOT00000012413(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0042493"|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008069(Cytochrome P450, E-class, group I, CYP2D-like)|interpro:IPR017972|interpro:IPR036396|rgd:2471|refseq:NP_036862.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:0zUTRPXGkJHquq/QEvdvSWu089s10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P00173 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925425|ensembl:ENSRNOP00000020446|uniprotkb:O35768 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:cyb5_rat(display_long)|uniprotkb:Cyb5a(gene name)|psi-mi:Cyb5a(display_short)|uniprotkb:Cyb5(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000015205(gene)|ensembl:ENSRNOT00000020446(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:1AQA|rcsb pdb:1AW3|rcsb pdb:1AXX|rcsb pdb:1B5A|rcsb pdb:1B5B|rcsb pdb:1BFX|rcsb pdb:1BLV|rcsb pdb:1I87|rcsb pdb:1I8C|rcsb pdb:1IB7|rcsb pdb:1IET|rcsb pdb:1IEU|rcsb pdb:1JEX|rcsb pdb:1MNY|rcsb pdb:2AXX|rcsb pdb:5XE4|rcsb pdb:5XEE|reactome:R-RNO-196836|reactome:R-RNO-9609523|interpro:IPR001199(Cytochrome b5)|rgd:620558|refseq:NP_071581.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:4A364umixUZMa5hgHIXWdEbQSXM10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:D4AEH9 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925673|ensembl:ENSRNOP00000052593 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:d4aeh9_rat(display_long)|uniprotkb:Agl(gene name)|psi-mi:Agl(display_short)|uniprotkb:Agl_predicted(gene name synonym)|uniprotkb:Amylo-alpha-1,6-glucosidase(gene name synonym)|uniprotkb:Dextrin 6-alpha-D-glucosidase(gene name synonym)|uniprotkb:Glycogen debrancher(gene name synonym)|uniprotkb:Glycogen debranching enzyme(gene name synonym)|uniprotkb:Oligo-1,4-1,4-glucantransferase(gene name synonym)|uniprotkb:rCG_28583(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000016214(gene)|ensembl:ENSRNOT00000055735(transcript)|go:"GO:0004133"(glycogen debranching enzyme activity)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009725"(response to hormone)|go:"GO:0016234"(inclusion body)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0102500"(beta-maltose 4-alpha-glucanotransferase activity)|interpro:IPR006421(Glycogen debranching enzyme)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR029436|interpro:IPR032788|interpro:IPR032790|interpro:IPR032792|reactome:R-RNO-6798695|reactome:R-RNO-70221|rgd:1306376|refseq:NP_001102034.1|refseq:XP_006233291.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:HKuAgY9F7lIzzRdikWhUtux/QSU10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P19132 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925590 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:frih_rat(display_long)|uniprotkb:Fth1(gene name)|psi-mi:Fth1(display_short)|uniprotkb:Fth(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060547"(negative regulation of necrotic cell death)|rgd:2635|refseq:NP_036980.1|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR014034(Ferritin, conserved site)|interpro:IPR008331(Ferritin and Dps)|reactome:R-RNO-6798695|reactome:R-RNO-917937 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:nO6WBlp7IuUnRD5HOYKvCeHN5XM10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P02793 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925566|ensembl:ENSRNOP00000028315|ensembl:ENSRNOP00000064683|uniprotkb:Q6P7T1 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:fril1_rat(display_long)|uniprotkb:Ftl1(gene name)|psi-mi:Ftl1(display_short)|uniprotkb:Ftl(gene name synonym)|uniprotkb:Ferritin L subunit 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000020843(gene)|ensembl:ENSRNOG00000031506(gene)|ensembl:ENSRNOT00000028315(transcript)|ensembl:ENSRNOT00000044711(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|reactome:R-RNO-6798695|reactome:R-RNO-917937|go:"GO:0008199"(ferric iron binding)|rgd:61813|refseq:NP_071945.3|refseq:XP_002726683.1|refseq:XP_002729599.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:ZIRr0ZoKDP4C8UGE1MX73rzV/+U10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) chebi:"CHEBI:28087" uniprotkb:P18163 intact:EBI-2507162 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long) psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 - rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:O08730 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925205 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:glyg_rat(display_long)|uniprotkb:Gyg1(gene name)|psi-mi:Gyg1(display_short)|uniprotkb:Gyg(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0005536"(glucose binding)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008466"(glycogenin glucosyltransferase activity)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0102751"("UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity")|interpro:IPR029044|rgd:621785|refseq:NP_112305.1|interpro:IPR002495(Glycosyl transferase, family 8)|reactome:R-RNO-3322077|reactome:R-RNO-6798695|reactome:R-RNO-70221 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:JyjpY/JnkJuSyjaf0T6+bSVJJD410116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P17625 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925187|uniprotkb:Q99MF8 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:gys2_rat(display_long)|uniprotkb:Gys2(gene name)|psi-mi:Gys2(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043265"(ectoplasm)|interpro:IPR008631(Glycogen synthase)|rgd:2773 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:QNELNI5iQTVtSt+ceSABN+YeZqY10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P07687 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925400|ensembl:ENSRNOP00000004780|ensembl:ENSRNOP00000074206 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:hyep_rat(display_long)|uniprotkb:Ephx1(gene name)|psi-mi:Ephx1(display_short)|uniprotkb:Eph-1(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0034312"(diol biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR010497(Epoxide hydrolase, N-terminal)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|reactome:R-RNO-211945|go:"GO:0016021"(integral component of membrane)|ensembl:ENSRNOG00000003515(gene)|ensembl:ENSRNOT00000004780(transcript)|ensembl:ENSRNOT00000085279(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|rgd:2557|refseq:NP_001029262.1|refseq:NP_036976.2 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:LS1te89hdccAXc+Pwo2zFg2tJ2I10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P20070 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2210833|uniprotkb:Q64569|uniprotkb:Q64720|ensembl:ENSRNOP00000061381 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:nb5r3_rat(display_long)|uniprotkb:Cyb5r3(gene name)|psi-mi:Cyb5r3(display_short)|uniprotkb:Dia1(gene name synonym)|uniprotkb:Diaphorase-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 refseq:XP_006242127.1|rgd:2502|refseq:NP_620232.1|ensembl:ENSRNOG00000009592(gene)|ensembl:ENSRNOT00000064700(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|rcsb pdb:1I7P|rcsb pdb:1IB0|rcsb pdb:1QX4|reactome:R-RNO-196836|reactome:R-RNO-211945|reactome:R-RNO-6798695 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:pUI578nLkddTgohGkVvdvRDKZIM10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P11598 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-916347 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:pdia3_rat(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:HIP-70(gene name synonym)|uniprotkb:Q-2(gene name synonym)|uniprotkb:Pdia3(gene name)|psi-mi:Pdia3(display_short)|uniprotkb:Erp60(gene name synonym)|uniprotkb:Grp58(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 rgd:68430|refseq:NP_059015.1|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0042825"(TAP complex)|go:"GO:0044321"(response to leptin)|go:"GO:0002931"(response to ischemia)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033595"(response to genistein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0045471"(response to ethanol)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1901423"(response to benzene)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1904148"(cellular response to nonylphenol)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|reactome:R-RNO-901042|reactome:R-RNO-983170|mint:P11598|interpro:IPR036249|interpro:IPR041868 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:l8gVAVgIclV0nr1n2t2XF33giuM10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:Q6IN01 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925257|ensembl:ENSRNOP00000042713|ensembl:ENSRNOP00000070738|uniprotkb:Q63759 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:ppr3b_rat(display_long)|uniprotkb:Ppp1r3b(gene name)|psi-mi:Ppp1r3b(display_short)|uniprotkb:Ppp1r4(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 4(gene name synonym)|uniprotkb:Protein phosphatase 1 subunit GL(gene name synonym)|uniprotkb:Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL(gene name synonym)|uniprotkb:33 kDa glycogen-binding protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000011474(gene)|go:"GO:0019888"(protein phosphatase regulator activity)|ensembl:ENSRNOT00000051720(transcript)|ensembl:ENSRNOT00000082091(transcript)|go:"GO:0019899"(enzyme binding)|go:"GO:0042587"(glycogen granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050196"([phosphorylase] phosphatase activity)|go:"GO:2001069"(glycogen binding)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030682|interpro:IPR038175|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0008157"(protein phosphatase 1 binding)|rgd:621600|refseq:NP_620267.2|refseq:XP_006253277.1|refseq:XP_006253278.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:6szn2GyJonjo9uOWx0n80grH79s10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P53534 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2696349 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:pygb_rat(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 interpro:IPR035090|rgd:3460|refseq:NP_037320.1|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|mint:P53534|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|reactome:R-RNO-6798695 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:WcV4oiXMS78KKpVSzVnziBt5uD810116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P09811 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925167|ensembl:ENSRNOP00000009183 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:pygl_rat(display_long)|uniprotkb:Pygl(gene name)|psi-mi:Pygl(display_short)|uniprotkb:Lgp(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000006388(gene)|ensembl:ENSRNOT00000009183(transcript)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|reactome:R-RNO-6798695|reactome:R-RNO-70221|go:"GO:0019842"(vitamin binding)|rgd:620687|refseq:NP_071604.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:DaAOdiwNKbeveYFsuiSL8OulNrw10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P55006 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925522|uniprotkb:P50169|uniprotkb:Q4KMB6 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:rdh7_rat(display_long)|uniprotkb:Rdh7(gene name)|psi-mi:Rdh7(display_short)|uniprotkb:Rdh3(gene name synonym)|uniprotkb:Retinol dehydrogenase 3(gene name synonym)|uniprotkb:Retinol dehydrogenase type III(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0042572"(retinol metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|rgd:631370|refseq:NP_598227.3|interpro:IPR036291 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:z2fTPl+m6WCjddEjFoaRM8uY5zM10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P62982 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-412946|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q63446|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:P49664|uniprotkb:Q9D2W3|uniprotkb:P62989|ensembl:ENSRNOP00000005872|ensembl:ENSRNOP00000048664 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:rs27a_rat(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 rgd:6489478|refseq:NP_112375.1|refseq:NP_001292372.1|ensembl:ENSRNOG00000004426(gene)|ensembl:ENSRNOG00000034246(gene)|ensembl:ENSRNOT00000005872(transcript)|ensembl:ENSRNOT00000049535(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|reactome:R-RNO-110312|reactome:R-RNO-110314|reactome:R-RNO-110320|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1253288|reactome:R-RNO-1295596|reactome:R-RNO-1358803|reactome:R-RNO-156827|reactome:R-RNO-168638|reactome:R-RNO-174048|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-179409|reactome:R-RNO-1799339|reactome:R-RNO-182971|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-201681|reactome:R-RNO-205043|reactome:R-RNO-209543|reactome:R-RNO-209560|reactome:R-RNO-2122948|reactome:R-RNO-2173788|reactome:R-RNO-2173791|reactome:R-RNO-2173795|reactome:R-RNO-2173796|reactome:R-RNO-2467813|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559585|reactome:R-RNO-2565942|reactome:R-RNO-2672351|reactome:R-RNO-3134975|reactome:R-RNO-349425|reactome:R-RNO-382556|reactome:R-RNO-445989|reactome:R-RNO-450302|reactome:R-RNO-450321|reactome:R-RNO-3769402|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-4641263|reactome:R-RNO-532668|reactome:R-RNO-5357905|reactome:R-RNO-5357956|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5654726|reactome:R-RNO-5654727|reactome:R-RNO-5654732|reactome:R-RNO-5654733|reactome:R-RNO-5655862|reactome:R-RNO-5656121|reactome:R-RNO-5656169|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5675221|reactome:R-RNO-5675482|reactome:R-RNO-5676590|reactome:R-RNO-5685942|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689877|reactome:R-RNO-5689880|reactome:R-RNO-5689896|reactome:R-RNO-5689901|reactome:R-RNO-5693565|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5696397|reactome:R-RNO-5696400|reactome:R-RNO-6781823|reactome:R-RNO-6782135|reactome:R-RNO-6782210|reactome:R-RNO-6783310|reactome:R-RNO-6791226|reactome:R-RNO-6804756|reactome:R-RNO-6804757|reactome:R-RNO-6804760|reactome:R-RNO-6807004|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69231|reactome:R-RNO-69481|reactome:R-RNO-69541|reactome:R-RNO-69601|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-75815|reactome:R-RNO-8849469|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8863795|reactome:R-RNO-8866652|reactome:R-RNO-8866654|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-901032|reactome:R-RNO-9013507|reactome:R-RNO-9020702|reactome:R-RNO-9033241|reactome:R-RNO-912631|reactome:R-RNO-917729|reactome:R-RNO-917937|reactome:R-RNO-937042|reactome:R-RNO-937072|reactome:R-RNO-9645460|reactome:R-RNO-9646399|reactome:R-RNO-9648002|reactome:R-RNO-9664873|reactome:R-RNO-9705462|reactome:R-RNO-9706369|reactome:R-RNO-975163|reactome:R-RNO-975956|reactome:R-RNO-975957|reactome:R-RNO-983168|reactome:R-RNO-8948747 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:AkJxTgRFL5RT5jWk5i3y4zX5tfA10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:Q9ES38 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925539|ensembl:ENSRNOP00000026574 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:s27a5_rat(display_long)|uniprotkb:Slc27a5(gene name)|psi-mi:Slc27a5(display_short)|uniprotkb:Acsb(gene name synonym)|uniprotkb:Fatp5(gene name synonym)|uniprotkb:Vlacsr(gene name synonym)|uniprotkb:Bile acid-CoA ligase(gene name synonym)|uniprotkb:Cholate--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase-related protein(gene name synonym)|uniprotkb:Fatty acid transport protein 5(gene name synonym)|uniprotkb:Solute carrier family 27 member 5(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000019626(gene)|ensembl:ENSRNOT00000026575(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046951"(ketone body biosynthetic process)|go:"GO:0047747"(cholate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030302|interpro:IPR042099|reactome:R-RNO-159418|reactome:R-RNO-193368|reactome:R-RNO-193775|rgd:708535|refseq:NP_077057.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:0R7WtqdUtwn9LZCE/tckGYiHO9810116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:Q5FVN1 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925219|ensembl:ENSRNOP00000003020 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:stbd1_rat(display_long)|uniprotkb:Stbd1(gene name)|psi-mi:Stbd1(display_short)|uniprotkb:Genethonin-1(gene name synonym)|uniprotkb:Glycophagy cargo receptor stbd1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 ensembl:ENSRNOG00000002218(gene)|ensembl:ENSRNOT00000003020(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030315"(T-tubule)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061723"(glycophagy)|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR034838|reactome:R-RNO-6798695|reactome:R-RNO-8980692|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013408|reactome:R-RNO-9013423|rgd:1311800|refseq:NP_001014010.1 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:5OFcPR3yhH2tX5xrJO+EcZf4d4810116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18163 uniprotkb:P08541 intact:EBI-916732|ensembl:ENSRNOP00000014235|ensembl:ENSRNOP00000072677 intact:EBI-2925281 psi-mi:acsl1_rat(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase, liver isozyme(gene name synonym)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acs1(gene name synonym)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:ud2b2_rat(display_long)|uniprotkb:Ugt2b(gene name)|psi-mi:Ugt2b(display_short)|uniprotkb:Ugt2b2(gene name synonym)|uniprotkb:3-hydroxyandrogen-specific UDPGT(gene name synonym)|uniprotkb:UDPGTr-4(gene name synonym)|uniprotkb:RLUG23(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2924999|imex:IM-20515-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2015|refseq:NP_036952.1|refseq:XP_008769476.1|refseq:XP_006253184.1|refseq:XP_006253185.1|refseq:XP_006253186.1|refseq:XP_006253187.1|refseq:XP_006253188.1|refseq:XP_006253189.1|ensembl:ENSRNOG00000010633(gene)|ensembl:ENSRNOT00000014235(transcript)|ensembl:ENSRNOT00000089501(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-RNO-2046105|reactome:R-RNO-2046106|reactome:R-RNO-75876 go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|rgd:3936|interpro:IPR035595|reactome:R-RNO-156588 - - - figure legend:Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2017/10/20 rogid:GL6cDpmfm0GALcS0fQy0tDiSUlo10116 rogid:nWjFlQMTdTew2ilMHYX8dxLR1Qo10116 intact-crc:B12210876B628BEC false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) chebi:"CHEBI:28087" uniprotkb:D4AEH9 intact:EBI-2507162 intact:EBI-2925673|ensembl:ENSRNOP00000052593 psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long) psi-mi:d4aeh9_rat(display_long)|uniprotkb:Agl(gene name)|psi-mi:Agl(display_short)|uniprotkb:Agl_predicted(gene name synonym)|uniprotkb:Amylo-alpha-1,6-glucosidase(gene name synonym)|uniprotkb:Dextrin 6-alpha-D-glucosidase(gene name synonym)|uniprotkb:Glycogen debrancher(gene name synonym)|uniprotkb:Glycogen debranching enzyme(gene name synonym)|uniprotkb:Oligo-1,4-1,4-glucantransferase(gene name synonym)|uniprotkb:rCG_28583(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2925693|imex:IM-20515-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSRNOG00000016214(gene)|ensembl:ENSRNOT00000055735(transcript)|go:"GO:0004133"(glycogen debranching enzyme activity)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009725"(response to hormone)|go:"GO:0016234"(inclusion body)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0102500"(beta-maltose 4-alpha-glucanotransferase activity)|interpro:IPR006421(Glycogen debranching enzyme)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR029436|interpro:IPR032788|interpro:IPR032790|interpro:IPR032792|reactome:R-RNO-6798695|reactome:R-RNO-70221|rgd:1306376|refseq:NP_001102034.1|refseq:XP_006233291.1 - - - figure legend:Supporting information Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2010/09/10 2014/10/16 - rogid:HKuAgY9F7lIzzRdikWhUtux/QSU10116 intact-crc:2261BDA58A3B46CB false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:28087" uniprotkb:Q9WUB3 intact:EBI-2507162 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2925717|imex:IM-20515-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) - - - figure legend:Supporting Information Fig 2B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 - rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:2454351F494D0697 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:28087" uniprotkb:Q8C7E7 intact:EBI-2507162 intact:EBI-2924824|ensembl:ENSMUSP00000054322|uniprotkb:Q147T8 psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long) psi-mi:stbd1_mouse(display_long)|uniprotkb:Stbd1(gene name)|psi-mi:Stbd1(display_short)|uniprotkb:D5Ertd593e(gene name synonym)|uniprotkb:Genethonin-1(gene name synonym)|uniprotkb:Glycophagy cargo receptor stbd1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Stapleton et al. (2010) pubmed:20391537|imex:IM-20515 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2925717|imex:IM-20515-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000047963(gene)|ensembl:ENSMUST00000050952(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030315"(T-tubule)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR034838|mint:Q8C7E7|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423|go:"GO:0061723"(glycophagy)|refseq:NP_780305.1 - - - figure legend:Supporting Information Fig 2B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2010/09/10 2014/10/16 - rogid:LlLqXKLm/5B/MHNATJ0yedkQ8Hk10090 intact-crc:2454351F494D0697 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)