#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A5PKW4	uniprotkb:P70398	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878645|mint:MINT-7897156|imex:IM-15052-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897161(identity)	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241|mint:MINT-7897158(identity)	-	-	-	figure legend:F3c|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	intact-crc:5EE1A7B4D2E38120|rigid:3gKuWn1OlkxYCBcQruToz6KPrBM	false	binding-associated region:756-869(MINT-7897169)|glutathione s tranferase tag:?-?(MINT-7986280)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:A5PKW4	uniprotkb:P70398	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878624|mint:MINT-7897129|imex:IM-15052-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897132(identity)	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241|mint:MINT-7897131(identity)	-	-	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	intact-crc:B990F3056ECAF6C4|rigid:3gKuWn1OlkxYCBcQruToz6KPrBM	false	his tag:?-?(MINT-7897140)	binding-associated region:674-1218(MINT-7897137)|glutathione s tranferase tag:?-?(MINT-7897134)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35226	uniprotkb:A5PKW4	intact:EBI-992034|uniprotkb:Q91V59|uniprotkb:Q9JJM0|uniprotkb:Q9JJM1|uniprotkb:Q9JJM2|uniprotkb:Q9JJM3|ensembl:ENSMUSP00000102857	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	psi-mi:psmd4_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Psmd4(gene name)|psi-mi:Psmd4(display_short)|uniprotkb:Mcb1(gene name synonym)	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878692|mint:MINT-7897228|imex:IM-15052-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032977.1|ensembl:ENSMUSG00000005625(gene)|ensembl:ENSMUST00000107237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|mint:O35226|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-4608870|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-8948751|refseq:NP_001268946.1|mint:MINT-7897230(identity)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897231(identity)	-	-	-	comment:homomint|comment:mint|figure legend:fs2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:foAsSSZ5pvYhKvPA4XUyZCVjo3010090	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	intact-crc:1D94CE984007C25B|rigid:zkC3ktPCN6clUNhT7UlSpU+0JDQ	false	glutathione s tranferase tag:?-?(MINT-7897237)	tag:?-?(MINT-7897241)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5PKW4	uniprotkb:P42567	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short)	psi-mi:"MI:0096"(pull down)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878727|mint:MINT-7897246|imex:IM-15052-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897252(identity)	ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7897248(identity)	-	-	-	comment:homomint|comment:domino|comment:mint|figure legend:fs2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090	intact-crc:F48D4E7535EBB41D|rigid:FuxWtO0Iuw02hLT88xQtCvx29f8	false	tag:?-?(MINT-7897253)	binding-associated region:847-897(MINT-7897256)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CG48	uniprotkb:A5PKW4	intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878782|mint:MINT-7897178|imex:IM-15052-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3|mint:MINT-7897181(identity)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897180(identity)	-	-	-	figure legend:f3e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21)	-	2010/05/27	2014/10/16	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	intact-crc:BC78619039808780|rigid:9nJ5zPHWrsrElwvCs+6GVfq4AnE	false	tandem tag:?-?(MINT-7897187)	tag:?-?(MINT-7897183)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q95LE0	uniprotkb:A5PKW4	intact:EBI-1549266|intact:EBI-2643534	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	psi-mi:q95le0_canlf(display_long)	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878857|mint:MINT-7897211|imex:IM-15052-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR015919(Cadherin-like)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR039808|interpro:IPR030049|mint:Q95LE0|go:"GO:0005509"(calcium ion binding)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045176"(apical protein localization)|go:"GO:0051234"(establishment of localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098609"(cell-cell adhesion)|mint:MINT-7897213(identity)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897214(identity)	go:"GO:0005923"(bicellular tight junction)	-	-	comment:homomint|comment:mint|figure legend:f5c f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/05/27	2014/10/16	rogid:OzarZALd0VlDjhuRhKJnzFpw2VE9615	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	intact-crc:E12E08B6276006D9|rigid:WipTjOxp81PcDDvHXSzAmO3EHfA	false	red fluorescent protein tag:?-?(MINT-7897216)	green fluorescent protein tag:?-?(MINT-7897220)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P70398	uniprotkb:A5PKW4	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878840|mint:MINT-7897195|imex:IM-15052-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241|mint:MINT-7897197(identity)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897198(identity)	go:"GO:0005923"(bicellular tight junction)	-	-	comment:homomint|comment:mint|figure legend:f5e f5f f5g fs4h fs4i fs4j|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/05/27	2014/10/16	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	intact-crc:4E3962CC976F7872|rigid:3gKuWn1OlkxYCBcQruToz6KPrBM	false	-	green fluorescent protein tag:?-?(MINT-7897293)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q95LE0	uniprotkb:P70398	intact:EBI-1549266|intact:EBI-2643534	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	psi-mi:q95le0_canlf(display_long)	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878941|mint:MINT-7897274|imex:IM-15052-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR015919(Cadherin-like)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR039808|interpro:IPR030049|mint:Q95LE0|go:"GO:0005509"(calcium ion binding)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045176"(apical protein localization)|go:"GO:0051234"(establishment of localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098609"(cell-cell adhesion)|mint:MINT-7897277(identity)	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241|mint:MINT-7897289(identity)	go:"GO:0005923"(bicellular tight junction)	-	-	comment:homomint|comment:mint|figure legend:fs4k fs4l|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/05/27	2014/10/16	rogid:OzarZALd0VlDjhuRhKJnzFpw2VE9615	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	intact-crc:2E6845ABB3F75C34|rigid:sulBGvktrCX/p7ZQWnMmSWagsSo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O97758	uniprotkb:A5PKW4	intact:EBI-6988333|intact:MINT-1778189	intact:EBI-719999|intact:EBI-1057652|uniprotkb:B1AKX7|uniprotkb:Q15673|uniprotkb:Q8IVG0|uniprotkb:D3DR87|intact:EBI-28973803|ensembl:ENSP00000020673|ensembl:ENSP00000384830	psi-mi:zo1_canlf(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:psd1_human(display_long)|uniprotkb:PSD(gene name)|psi-mi:PSD(display_short)|uniprotkb:EFA6(gene name synonym)|uniprotkb:KIAA2011(gene name synonym)|uniprotkb:PSD1(gene name synonym)|uniprotkb:TYL(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 1(gene name synonym)|uniprotkb:EFA6A(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6(gene name synonym)|uniprotkb:Exchange factor for ARF6 A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Théard et al. (2010)	pubmed:20339350|imex:IM-15052|mint:MINT-7893893|doi:10.1038/emboj.2010.46	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7878894|mint:MINT-7897260|imex:IM-15052-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR035597|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|refseq:NP_001003140.1|mint:O97758|interpro:IPR036028|interpro:IPR036034|mint:MINT-7897262(identity)	ensembl:ENSP00000020673|ensembl:ENSP00000384830|ensembl:ENST00000611678|ensembl:ENSP00000481250|refseq:NP_002770.3|ensembl:ENSG00000059915(gene)|ensembl:ENST00000020673(transcript)|ensembl:ENST00000406432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0098999"(extrinsic component of postsynaptic endosome membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:A5PKW4|refseq:NP_001257894.1|refseq:NP_001257895.1|refseq:XP_011538270.1|refseq:XP_011538271.1|refseq:XP_016871922.1|refseq:XP_016871923.1|mint:MINT-7897263(identity)	go:"GO:0005923"(bicellular tight junction)	comment:mint|function:The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions	-	comment:homomint|comment:domino|comment:mint|figure legend:fs3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/05/27	2014/10/16	rogid:ahJn9QpY395wArDFwZ2FwDxf6s89615	rogid:7yiyIJ5gJLRVJbXmjGyYyoEwIGc9606	intact-crc:845CBEC7FB2869C1|rigid:fzC5zXcBA2kFJpmtHpOpQHbROiM	false	-	binding-associated region:756-869(MINT-7897271)|green fluorescent protein tag:?-?(MINT-7986323)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0396"(predetermined participant)