#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03348 uniprotkb:P04610 intact:EBI-7845043|intact:MINT-7909008 intact:EBI-7845069|intact:MINT-7908963 psi-mi:gag_hv1br(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:tat_hv1br(display_long)|uniprotkb:tat(gene name)|psi-mi:tat(display_short)|uniprotkb:Transactivating regulatory protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Rayne et al. (2010) pubmed:20224549|imex:IM-15074|mint:MINT-7908936|doi:10.1038/emboj.2010.32 taxid:11686(hv1br)|taxid:11686("Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)") taxid:11686(hv1br)|taxid:11686("Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7845035|mint:MINT-7909043|imex:IM-15074-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0039702"(viral budding via host ESCRT complex)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR014817(Gag protein p6)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR036875|mint:MINT-7909046(identity) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0052312"(obsolete modulation of transcription in other organism involved in symbiotic interaction)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1990970"(trans-activation response element binding)|rcsb pdb:1JFW|rcsb pdb:1JM4|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|interpro:IPR036963|mint:MINT-7909045(identity) go:"GO:0005886"(plasma membrane) comment:mint comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f2d sf1 f5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-t cells cd 4+)|taxid:9606(Homo sapiens) - 2010/06/21 2014/10/16 rogid:l6pIf3OAVcmsANexDWcmVjXbjiY11686 rogid:2CpM6vwxCUC3FXK4nqymOUKxHsM11686 intact-crc:E2547AB46EAAA6C6|rigid:nBqhG419oSY3OhC+QJmMFz6Txzs false polyprotein fragment:133-363(MINT-7909053) - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)