#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-2643306 intact:EBI-2643309 - - psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643227|imex:IM-13770-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0320"(ribonucleic acid) ensembl:ENSMUSG00000034957(see-also) ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. comment:"A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins. The mobility of hnRNP E2:miR-328 complexes was identical to that formed using the uORF/spacer region of CEBPA mRNA (CEBPA uORF) oligoribonucleotide, and miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF."|antagonist:CEBPA uORF|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 crc64:2895F6928FEAD13D intact-crc:E64449CF8F7B5536 false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 uniprotkb:Q15366 - intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643227|imex:IM-13770-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034957(see-also) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - comment:"A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins. The mobility of hnRNP E2:miR-328 complexes was identical to that formed using the uORF/spacer region of CEBPA mRNA (CEBPA uORF) oligoribonucleotide, and miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF."|antagonist:CEBPA uORF|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:E64449CF8F7B5536 false - maltose binding protein tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 intact:EBI-2643309 - - psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643295|imex:IM-13770-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0320"(ribonucleic acid) ensembl:ENSMUSG00000034957(see-also) ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. antagonist:mir-328|comment:miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 crc64:2895F6928FEAD13D intact-crc:02CB4AAEFC9CD85A false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 uniprotkb:Q15366 - intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643295|imex:IM-13770-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034957(see-also) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - antagonist:mir-328|comment:miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:02CB4AAEFC9CD85A false - maltose binding protein tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 intact:EBI-2643309 - - psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643331|imex:IM-13770-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0320"(ribonucleic acid) ensembl:ENSMUSG00000034957(see-also) ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. comment:"A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins. The mobility of hnRNP E2:miR-328 complexes was identical to that formed using the uORF/spacer region of CEBPA mRNA (CEBPA uORF) oligoribonucleotide, and miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF."|antagonist:CEBPA uORF|figure legend:Fig 2A.|antagonist:"Imatinib, an inhibitor of the TK (tyrosine kinase) domain in abl (the Abelson proto-oncogene), c-kit and PDGF-R."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 crc64:2895F6928FEAD13D intact-crc:A7A98D5F54A6EE7E false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 uniprotkb:Q61990 - intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643331|imex:IM-13770-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034957(see-also) refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - comment:"A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins. The mobility of hnRNP E2:miR-328 complexes was identical to that formed using the uORF/spacer region of CEBPA mRNA (CEBPA uORF) oligoribonucleotide, and miR-328 binding to hnRNP E2 was four times stronger than that of CEBPA uORF."|antagonist:CEBPA uORF|figure legend:Fig 2A.|antagonist:"Imatinib, an inhibitor of the TK (tyrosine kinase) domain in abl (the Abelson proto-oncogene), c-kit and PDGF-R."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:A7A98D5F54A6EE7E false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 intact:EBI-2643309 - - psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643342|imex:IM-13770-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0320"(ribonucleic acid) ensembl:ENSMUSG00000034957(see-also) ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. antagonist:mir-328|figure legend:Fig 2A.|antagonist:"Imatinib, an inhibitor of the TK (tyrosine kinase) domain in abl, c-kit and PDGF-R."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 crc64:2895F6928FEAD13D intact-crc:EDAD4CEB3B02B60D false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-2643306 uniprotkb:Q61990 - intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643342|imex:IM-13770-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034957(see-also) refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - antagonist:mir-328|figure legend:Fig 2A.|antagonist:"Imatinib, an inhibitor of the TK (tyrosine kinase) domain in abl, c-kit and PDGF-R."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 crc64:1FAA925D76CD8458 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:EDAD4CEB3B02B60D false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q15366 intact:EBI-2643309 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643380|imex:IM-13770-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. comment:A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins.|figure legend:Fig 2B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:2895F6928FEAD13D intact-crc:E7E3162C908D6F85 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15366 intact:EBI-2643306 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643386|imex:IM-13770-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000034957(see-also) - - - figure legend:Fig 2B.|comment:A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:1FAA925D76CD8458 intact-crc:DF82FF82C2E590AD false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15366 intact:EBI-2643428 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mut-mir328(display_short)|psi-mi:EBI-2643428(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643431|imex:IM-13770-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000070130(see-also) - - comment:seed sequence differs from non-mutant form comment:Mutant miR-328 binds both endogenous and ectopic hnRNP E2 at higher affinity than wild-type miR-328, suggesting that the C-rich character rather than the seed sequence is important for hnRNP E2 interaction.|figure legend:Fig 2B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:2895E88D74D007E7 intact-crc:BF80FE6F8670E7BC false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15366 intact:EBI-2643428 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mut-mir328(display_short)|psi-mi:EBI-2643428(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643414|imex:IM-13770-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000070130(see-also) - - comment:seed sequence differs from non-mutant form comment:Mutant miR-328 binds both endogenous and ectopic hnRNP E2 at higher affinity than wild-type miR-328, suggesting that the C-rich character rather than the seed sequence is important for hnRNP E2 interaction.|figure legend:Fig 2B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:2895E88D74D007E7 intact-crc:C65A880389ABA8B8 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15366 intact:EBI-2643306 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:cebpa-uorf(display_short)|psi-mi:EBI-2643306(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643421|imex:IM-13770-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000034957(see-also) - - - figure legend:Fig 2B.|comment:A 32P-labeled miR-328 oligoribonucleotide efficiently formed a complex with recombinant, endogenous, and ectopic hnRNP E2 proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:1FAA925D76CD8458 intact-crc:603E656CB8C3ED83 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15366 intact:EBI-2643309 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 - psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mir-328probe(display_short)|psi-mi:EBI-2643309(display_long) psi-mi:"MI:0430"(nucleic acid uv cross-linking assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643925|imex:IM-13770-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 ensembl:ENSMUSG00000070130(see-also) - - comment:sequence is the same in human and mouse. figure legend:Fig 2E.|comment:"Ectopic miR-181b (and miR-330) did neither interact with hnRNP E2 nor significantly alter levels of the hnRNP E2:CEBPA complex. Thus, miR-328 specifically competes with CEBPA mRNA for binding to hnRNP E2."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 crc64:2895F6928FEAD13D intact-crc:CAEE30E7BC546C16 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2643643 uniprotkb:Q61990 ensembl:ENSMUSG00000070130 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643527|imex:IM-13770-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:Fig 2C.|antagonist:"Imatinib, an inhibitor of the TK (tyrosine kinase) domain in abl, c-kit and PDGF-R."|comment:Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:2FE71436991A3F60 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643662 uniprotkb:Q61990 ensembl:ENSMUSG00000034957 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa_mrna(display_short)|psi-mi:EBI-2643662(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643636|imex:IM-13770-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:Fig 2D, 2E.|comment:"Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2. miR-328 binding to hnRNP E2 impaired hnRNP E2:CEBPA association."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:2A354A4D3E70A118 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15366 intact:EBI-2643643 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 ensembl:ENSMUSG00000070130 psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643629|imex:IM-13770-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - - figure legend:Fig S1C.|comment:Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 - intact-crc:1B8F5602EAB8893B false flag tag:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61990 intact:EBI-2643643 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 ensembl:ENSMUSG00000070130 psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643657|imex:IM-13770-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - - figure legend:Fig 2D.|comment:"Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2. miR-328 binding to hnRNP E2 impaired hnRNP E2:CEBPA association."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 - intact-crc:C8AA2ED7C61B5223 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643662 uniprotkb:Q61990 ensembl:ENSMUSG00000034957 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa_mrna(display_short)|psi-mi:EBI-2643662(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643699|imex:IM-13770-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:"Fig 2E (very faint band visible)."|comment:"Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2. miR-328 binding to hnRNP E2 impaired hnRNP E2:CEBPA association."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:EC6E1A3600DF3E64 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643662 uniprotkb:Q61990 ensembl:ENSMUSG00000034957 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa_mrna(display_short)|psi-mi:EBI-2643662(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643899|imex:IM-13770-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:Fig 2E.|comment:"Ectopic miR-181b neither interacted with hnRNP E2 nor significantly altered levels of the hnRNP E2:CEBPA complex."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:8826D68F9E272753 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61990 intact:EBI-2643662 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 ensembl:ENSMUSG00000034957 psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:cebpa_mrna(display_short)|psi-mi:EBI-2643662(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643971|imex:IM-13770-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - - figure legend:Fig S1D, 5D.|comment:"Association of miR-328 and CEBPA mRNA to endogenous hnRNP E2 in anti-hnRNP E2 RIPs from empty vector- and miR-328-expressing 6.15 and 6.15-uORF cells. miR-328 expression and, therefore, formation of the hnRNP E2:miR-328 complex markedly decreased levels of the hnRNP E2-bound CEBPA mRNA."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 - intact-crc:6BD851435930C1F6 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643643 uniprotkb:Q61990 ensembl:ENSMUSG00000070130 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643986|imex:IM-13770-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:Fig S1D, 5D.|comment:Association of miR-328 and CEBPA mRNA to endogenous hnRNP E2 in anti-hnRNP E2 RIPs from empty vector- and miR-328-expressing 6.15 and 6.15-uORF cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:E13A12B2A33A0B8D false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643662 uniprotkb:Q61990 ensembl:ENSMUSG00000034957 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:cebpa_mrna(display_short)|psi-mi:EBI-2643662(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644003|imex:IM-13770-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:Fig S1D, 5D.|comment:"Association of miR-328 and CEBPA mRNA to endogenous hnRNP E2 in anti-hnRNP E2 RIPs from empty vector- and miR-328-expressing 6.15 and 6.15-uORF cells. miR-328 expression and, therefore, formation of the hnRNP E2:miR-328 complex markedly decreased levels of the hnRNP E2-bound CEBPA mRNA."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:E3EBB58005FB00B1 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97473 uniprotkb:Q61990 intact:EBI-2644020|uniprotkb:Q99M41|ensembl:ENSMUSP00000023813 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:trbp2_mouse(display_long)|uniprotkb:Tarbp2(gene name)|psi-mi:Tarbp2(display_short)|uniprotkb:Prbp(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym)|uniprotkb:Protamine-1 RNA-binding protein(gene name synonym) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644044|imex:IM-13770-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033345.2|ensembl:ENSMUSG00000023051(gene)|ensembl:ENSMUST00000023813(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR044470|interpro:IPR044471|reactome:R-MMU-203927|reactome:R-MMU-426486 refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig 3A.|comment:An evaluation as to whether hnRNP E2 is in complex with Dicer, Ago2, or TRBP2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:YF0XnCWZNv2/AK2ONvSI+Jkwi1I10090 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:F0B95EA663B23C59|rigid:eL/7a3RTrzOWD/mYN4vsMEQw40s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R418 uniprotkb:P97473 intact:EBI-2644051|uniprotkb:Q8R419 intact:EBI-2644020|uniprotkb:Q99M41|ensembl:ENSMUSP00000023813 psi-mi:dicer_mouse(display_long)|uniprotkb:Dicer1(gene name)|psi-mi:Dicer1(display_short)|uniprotkb:Dicer(gene name synonym)|uniprotkb:Mdcr(gene name synonym)|uniprotkb:Double-strand-specific ribonuclease mDCR-1(gene name synonym) psi-mi:trbp2_mouse(display_long)|uniprotkb:Tarbp2(gene name)|psi-mi:Tarbp2(display_short)|uniprotkb:Prbp(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym)|uniprotkb:Protamine-1 RNA-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644088|imex:IM-13770-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001834"(trophectodermal cell proliferation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0006396"(RNA processing)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010660"(regulation of muscle cell apoptotic process)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0014835"(myoblast differentiation involved in skeletal muscle regeneration)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0048565"(digestive tract development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051225"(spindle assembly)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061309"(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:"GO:0061548"(ganglion development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070173"(regulation of enamel mineralization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0071335"(hair follicle cell proliferation)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:2000628"(regulation of miRNA metabolic process)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000999(Ribonuclease III)|go:"GO:0021522"(spinal cord motor neuron differentiation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR044441|rcsb pdb:3C4B|rcsb pdb:3C4T|interpro:IPR038248|dip:DIP-29721N|reactome:R-MMU-203927|reactome:R-MMU-426486 refseq:NP_033345.2|ensembl:ENSMUSG00000023051(gene)|ensembl:ENSMUST00000023813(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR044470|interpro:IPR044471|reactome:R-MMU-203927|reactome:R-MMU-426486 psi-mi:"MI:0469"(intact) - - figure legend:Fig 3B.|comment:TRBP2 was readily detectable in anti-Dicer IPs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:WTvPhOwCtJat0OjGAIn33JJ4ZEo10090 rogid:YF0XnCWZNv2/AK2ONvSI+Jkwi1I10090 intact-crc:EB9B9FCCFA6CEAEA|rigid:wd3LdWGd3ZUzc+5oEWwSoEi+WTE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2643643 uniprotkb:Q61990 ensembl:ENSMUSG00000070130 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643997|imex:IM-13770-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:S1D.|comment:Association of miR-328 and CEBPA mRNA to endogenous hnRNP E2 in anti-hnRNP E2 RIPs from empty vector- and miR-328-expressing 6.15 and 6.15-uORF cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 intact-crc:83E572FD20C5C3AD false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2643643 uniprotkb:Q8R418 ensembl:ENSMUSG00000070130 intact:EBI-2644051|uniprotkb:Q8R419 psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:dicer_mouse(display_long)|uniprotkb:Dicer1(gene name)|psi-mi:Dicer1(display_short)|uniprotkb:Dicer(gene name synonym)|uniprotkb:Mdcr(gene name synonym)|uniprotkb:Double-strand-specific ribonuclease mDCR-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644101|imex:IM-13770-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001834"(trophectodermal cell proliferation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0006396"(RNA processing)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010660"(regulation of muscle cell apoptotic process)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0014835"(myoblast differentiation involved in skeletal muscle regeneration)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0048565"(digestive tract development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051225"(spindle assembly)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061309"(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:"GO:0061548"(ganglion development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070173"(regulation of enamel mineralization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0071335"(hair follicle cell proliferation)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:2000628"(regulation of miRNA metabolic process)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000999(Ribonuclease III)|go:"GO:0021522"(spinal cord motor neuron differentiation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR044441|rcsb pdb:3C4B|rcsb pdb:3C4T|interpro:IPR038248|dip:DIP-29721N|reactome:R-MMU-203927|reactome:R-MMU-426486 - - - figure legend:Fig 3C, lane 4.|comment:RIP assays revealed miR-328 in complex with both Dicer and Ago2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:WTvPhOwCtJat0OjGAIn33JJ4ZEo10090 intact-crc:B2C24A16C04EF815 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61990 intact:EBI-2643643 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 ensembl:ENSMUSG00000070130 psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644109|imex:IM-13770-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - - figure legend:Fig 3C, lane 5.|comment:"The presence of readily detectable hnRNP E2:miR-328 complex in RIP assays on Dicer-immunodepleted lysates suggests that miR-328 might interact with hnRNP E2 in a RISC-independent manner."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 - intact-crc:F9B0B32BEE9E57FB false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8CJG0 intact:EBI-2643643 intact:EBI-528299|uniprotkb:A1A563|uniprotkb:Q4VAB3|uniprotkb:Q571J6|ensembl:ENSMUSP00000042207 ensembl:ENSMUSG00000070130 psi-mi:ago2_mouse(display_long)|uniprotkb:Ago2(gene name)|psi-mi:Ago2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:Eif2c2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:Kiaa4215(gene name synonym)|uniprotkb:Piwi/argonaute family protein meIF2C2(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644117|imex:IM-13770-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_694818.3|ensembl:ENSMUSG00000036698(gene)|ensembl:ENSMUST00000044113(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016442"(RISC complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q8CJG0|reactome:R-MMU-203927|reactome:R-MMU-426486|reactome:R-MMU-426496|reactome:R-MMU-5578749|dip:DIP-35014N - - - - figure legend:Fig 3C, lane 7.|comment:RIP assays revealed miR-328 in complex with both Dicer and Ago2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:1waGxV2TyNC9zsGyfTKHjUd1ENo10090 - intact-crc:42A9EEC9497D5B6D false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000070130 uniprotkb:P53566 intact:EBI-2644253 intact:EBI-2644207|uniprotkb:Q91XB6|ensembl:ENSMUSP00000096129 psi-mi:mir-328_mouse_gene(display_short)|psi-mi:ENSMUSG00000070130(display_long) psi-mi:cebpa_mouse(display_long)|uniprotkb:Cebpa(gene name)|psi-mi:Cebpa(display_short)|uniprotkb:Cebp(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644206|imex:IM-13770-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_031704.2|refseq:NP_001274443.1|refseq:NP_001274444.1|refseq:NP_001274450.1|ensembl:ENSMUSG00000034957(gene)|ensembl:ENSMUST00000042985(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P53566|reactome:R-MMU-9616222|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|dip:DIP-44054N - comment:human/mouse-conserved C/EBPa-binding sites. - figure legend:Fig 6C.|comment:Physical interaction between HA-CEBPa and the miR-328 promoter region was detected at regions -1119 to -1112 and -565 to -557. These are mouse/human conserved CEBPa-binding sites.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 - rogid:pGJ6XTpLySPEYPc9uYgeawD6WTk10090 intact-crc:6EA2B4B1838AD494 false - ha tag:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15366 intact:EBI-2643643 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 ensembl:ENSMUSG00000070130 psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:mir-328(display_short)|psi-mi:EBI-2643643(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Eiring et al. (2010) imex:IM-13770|pubmed:20211135 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2643574|imex:IM-13770-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - - figure legend:Fig S1C.|comment:Ectopic expression of miR-328 at physiological levels also resulted in complex formation with both ectopic and endogenous hnRNP E2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-32dcl3)|taxid:10090(Mus musculus 32Dcl3 murine myeloid cell line dependent on IL3.) - 2010/04/19 2014/10/16 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 - intact-crc:F6564BB542117FFC false flag tag:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)