#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q4KMA2	uniprotkb:D4A037	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649816|ensembl:ENSRNOP00000013031	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:d4a037_rat(display_long)|uniprotkb:Fam204a(gene name)|psi-mi:Fam204a(display_short)|uniprotkb:RGD1305500_predicted(gene name synonym)|uniprotkb:rCG_57604(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_001100918.1|rgd:1305500|ensembl:ENSRNOG00000009830(gene)|ensembl:ENSRNOT00000013031(transcript)|interpro:IPR037690|refseq:XP_017444574.1	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:Ua6/gdM+7F/gWT402itv7b03AuY10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:D4AEH3	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649804|ensembl:ENSRNOP00000019104	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:d4aeh3_rat(display_long)|uniprotkb:Psmd7(gene name)|psi-mi:Psmd7(display_short)|uniprotkb:Psmd7_predicted(gene name synonym)|uniprotkb:rCG_51362(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_001100896.1|rgd:1306902|ensembl:ENSRNOG00000014097(gene)|ensembl:ENSRNOT00000019104(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-75815	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:+dQm8XckkeeM7wNqTBdwjohX8OY10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P07340	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	intact:EBI-2649720	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	-	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:d3za28_rat(display_short)|psi-mi:EBI-2649720(display_long)|uniprotkb:Fam219b(gene name)|psi-mi:Fam219b(display_short)|uniprotkb:RGD1310727(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	uniprotkb:D3ZA28(uniprot-removed-ac)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:PmAZclw4dD5t5ATYDpHn+vLOWLA10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q6PCU0	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2255880|uniprotkb:F7FFJ9|ensembl:ENSRNOP00000061946	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q6pcu0_rat(display_long)|uniprotkb:rCG_55763(orf name)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:Atp5c1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_446277.1|rgd:620011|ensembl:ENSRNOG00000019223(gene)|ensembl:ENSRNOT00000064802(transcript)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:Kz7DIGPkWP62t8HP2eOEnDQrAv810116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P19511	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2255901|ensembl:ENSRNOP00000021920|ensembl:ENSRNOP00000065147	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:at5f1_rat(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f(gene name synonym)|uniprotkb:Atp5f1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:620041|refseq:NP_599192.1|refseq:XP_003749420.1|ensembl:ENSRNOG00000016000(gene)|ensembl:ENSRNOG00000046299(gene)|ensembl:ENSRNOT00000021920(transcript)|ensembl:ENSRNOT00000075083(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P19511|reactome:R-RNO-163210|reactome:R-RNO-8949613	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:QAiktmxMbugxEHz2O+zYw8oHMPk10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P10719	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916266|uniprotkb:Q499W0	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:atpb_rat(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:621368|refseq:NP_599191.1|interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009631"(cold acclimation)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904643"(response to curcumin)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-1268020|reactome:R-RNO-163210|reactome:R-RNO-8949613|interpro:IPR027417|mint:P10719|interpro:IPR036121	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:K1RREEkTYSnEnU2leNpq3SCa3wc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P48004-2	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-917591	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:p48004-2(display_long)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	intact:EBI-917581(psa7_rat)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:eAvQrLXsGR0Tapu8Yu37fku0gsw10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P0CD94	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649713|ensembl:ENSRNOP00000064397	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:uqcc3_rat(display_long)|uniprotkb:Uqcc3(gene name)|psi-mi:Uqcc3(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_001162132.1|rgd:1597344|ensembl:ENSRNOG00000045561(gene)|ensembl:ENSRNOT00000074747(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042407"(cristae formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR027896	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:/PA3uogN4oGzYgpP80FtqoV4qXI10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q6Y2E6	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649576|ensembl:ENSRNOP00000027266	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q6y2e6_rat(display_long)|uniprotkb:rCG_34421(orf name)|uniprotkb:Rab40c(gene name)|psi-mi:Rab40c(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:727914|refseq:NP_872616.1|ensembl:ENSRNOG00000020067(gene)|ensembl:ENSRNOT00000027266(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR036036|reactome:R-RNO-8873719|refseq:XP_006246043.2	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:ZYZSo//vNrfsDcxrri79hvRkVEo10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P21670	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916847|ensembl:ENSRNOP00000018173	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psa4_rat(display_long)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:61846|refseq:NP_058977.1|ensembl:ENSRNOG00000013493(gene)|ensembl:ENSRNOT00000018173(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|rcsb pdb:6TU3|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:7fTJxarnOfFJ6AdMuJXQsUIz4eA10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:B2RZ97	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649596	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:b2rz97_rat(display_long)|uniprotkb:Kcmf1(gene name)|psi-mi:Kcmf1(display_short)|uniprotkb:LOC684322(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase KCMF1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR008598(Drought induced 19)|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001121664.1|interpro:IPR039858|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099536"(synaptic signaling)|go:"GO:0045202"(synapse)|rgd:1591490|interpro:IPR043145	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:SJpQkWGps9hK1bRTVo/u0c95iEg10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:D3ZP81	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649614|ensembl:ENSRNOP00000010296	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:d3zp81_rat(display_long)|uniprotkb:Rnf43(gene name)|psi-mi:Rnf43(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_001129393.1|ensembl:ENSRNOG00000007606(gene)|ensembl:ENSRNOT00000010296(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0038018"(Wnt receptor catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072089"(stem cell proliferation)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040700|reactome:R-RNO-4641263|rgd:1305204	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:+H521bWDgF0528jQgc4guhf+99o10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P18421	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916762	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psb1_rat(display_long)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)|uniprotkb:Psmb1(gene name)|psi-mi:Psmb1(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR029055|rgd:621092|refseq:NP_446042.1|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|reactome:R-RNO-8932339|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035202|rcsb pdb:6TU3|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:lkLXXyjxqUfmYPrGfPnXtXeEUP410116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P15999	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916646|uniprotkb:Q6P753	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:atpa_rat(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:619993|refseq:NP_075581.1|interpro:IPR020003|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR033732|interpro:IPR027417|mint:P15999|interpro:IPR038376|interpro:IPR036121|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0045471"(response to ethanol)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:Jkbhz0cHR3egHpKo/n1Ex4EbnUI10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P13233	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640672|uniprotkb:Q4V796|uniprotkb:Q64575|ensembl:ENSRNOP00000023875	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:cn37_rat(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2368|refseq:NP_036941.1|ensembl:ENSRNOG00000017496(gene)|ensembl:ENSRNOT00000023872(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P13233|rcsb pdb:2ILX	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:+0AAow8yyo0d6aKTghtTmcS2SZw10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P11275	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640645	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:B5DEN5	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640627|ensembl:ENSRNOP00000036882	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:b5den5_rat(display_long)|uniprotkb:Eef1b2(gene name)|psi-mi:Eef1b2(display_short)|uniprotkb:rCG_22471(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1311415|refseq:NP_001102269.1|ensembl:ENSRNOG00000024186(gene)|ensembl:ENSRNOT00000034740(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:B5DEN5|reactome:R-RNO-156842	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:u9Z0/lB618WDZdrKh+UfuFX0nEk10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P85834	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640608|ensembl:ENSRNOP00000025203	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:eftu_rat(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1305501|refseq:NP_001099765.1|ensembl:ENSRNOG00000018604(gene)|ensembl:ENSRNOT00000025203(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P85834	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:7ijVJSb0XSiqlNjp70i4FXEF2z810116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P60881	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-1027214|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|intact:EBI-11701410	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:snp25_rat(display_long)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|rcsb pdb:1JTH|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:1URQ|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5LOB|rcsb pdb:5LOW|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MDO|rcsb pdb:6MDP|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-449836|reactome:R-RNO-6798695|reactome:R-RNO-888590|rgd:3728|refseq:NP_112253.1|refseq:NP_001257504.1|refseq:NP_001257505.1|mint:P60881|dip:DIP-29205N	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P63018	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-433431|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q4FZY7|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:hsp7c_rat(display_long)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:621725|refseq:NP_077327.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008380"(RNA splicing)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0010045"(response to nickel cation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0044849"(estrous cycle)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990834"(response to odorant)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1CKR|rcsb pdb:1Q2G|rcsb pdb:1UD0|rcsb pdb:2V7Z|rcsb pdb:7HSC|mint:P63018|dip:DIP-33262N	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q6P9T8	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-919099	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:tbb4b_rat(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|rgd:735101|refseq:NP_954525.1|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR023123|mint:Q6P9T8|interpro:IPR036525|interpro:IPR037103|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:1RJgLTml+eflSvmnOyLoI1pFFTc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q5XIF6	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2255850|ensembl:ENSRNOP00000004797	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:tba4a_rat(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1359623|refseq:NP_001007005.1|ensembl:ENSRNOG00000003597(gene)|ensembl:ENSRNOT00000004797(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q5XIF6|reactome:R-RNO-114608|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P60711	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q4QRB4	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-919537|uniprotkb:Q8K5B6|ensembl:ENSRNOP00000023452	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:tbb3_rat(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)|uniprotkb:Neuron-specific class III beta-tubulin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:628595|refseq:NP_640347.2|ensembl:ENSRNOG00000017209(gene)|ensembl:ENSRNOT00000023452(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q4QRB4|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q5XIC6	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640568|ensembl:ENSRNOP00000004283	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q5xic6_rat(display_long)|uniprotkb:Psmd12(gene name)|psi-mi:Psmd12(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1359305|refseq:NP_001005875.1|ensembl:ENSRNOT00000004283(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:6EPC|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|rcsb pdb:6EPD|ensembl:ENSRNOG00000003117(gene)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:nBDiE5U6UiLM6DTh6NBk7NHYx7E10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q4V8E2	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640579|ensembl:ENSRNOP00000071068|uniprotkb:F1LMW6	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q4v8e2_rat(display_long)|uniprotkb:Psmd14(gene name)|psi-mi:Psmd14(display_short)|uniprotkb:rCG_26455(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1594532|refseq:NP_001020860.1|ensembl:ENSRNOG00000061129(gene)|ensembl:ENSRNOT00000082769(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-5689901|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-5632684	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc410116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:B5DEP6	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640556	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:b5dep6_rat(display_long)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040773|interpro:IPR040780|go:"GO:0000502"(proteasome complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:epwBgssqE4Kc8JHYw1ovtLE3co010116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q3B8P5	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640544	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q3b8p5_rat(display_long)|uniprotkb:Psmd8(gene name)|psi-mi:Psmd8(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|rgd:1309842|refseq:NP_001094301.1|interpro:IPR033464|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:vshIG2dFEG9wfwgB/FULzJE0Kkk10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q9ESH1	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640530	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q9esh1_rat(display_long)|uniprotkb:Psmd4(gene name)|psi-mi:Psmd4(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR002035(von Willebrand factor, type A)|rgd:621109|refseq:XP_006232986.1|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042044"(fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR036465	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:cHu2JoRdzOdVap/LCpM1FuIBYnc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:B0BN93	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640503|ensembl:ENSRNOP00000019642	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psd13_rat(display_long)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:Psmd13(gene name)|psi-mi:Psmd13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1305236|refseq:NP_001102395.1|ensembl:ENSRNOG00000014109(gene)|ensembl:ENSRNOT00000019642(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|interpro:IPR036390|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-5632684	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:OxZvvCQDnvO8fCnxDYNi3V8J0nU10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:O88761	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-915698	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psmd1_rat(display_long)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)|uniprotkb:Psmd1(gene name)|psi-mi:Psmd1(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:621669|refseq:NP_114184.1|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-RNO-8932339|interpro:IPR040623|interpro:IPR035266|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:U5l9uQXGOiSSbuoA0e0l3fWy+Bg10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q63569	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918627|uniprotkb:P97638	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs6a_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Spermatogenic cell/sperm-associated Tat-binding protein homolog SATA(gene name synonym)|uniprotkb:Psmc3(gene name)|psi-mi:Psmc3(display_short)|uniprotkb:Tbp1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:61905|refseq:NP_113783.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|reactome:R-RNO-8932339|interpro:IPR027417|interpro:IPR035254|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR032501|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:XFSQuVQN6D2YQ2pEVhaQUYmKE/410116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q63347	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918567|uniprotkb:Q62690|uniprotkb:Q6P7R9	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs7_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:3428|refseq:NP_150239.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|reactome:R-RNO-8932339|interpro:IPR027417|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035245|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mkLED0sa4m4p2Q/87z8Fe2h8J0410116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q63570	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918637|ensembl:ENSRNOP00000025819	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs6b_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:Psmc4(gene name)|psi-mi:Psmc4(display_short)|uniprotkb:Tbp7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:621102|refseq:NP_476463.1|ensembl:ENSRNOG00000018994(gene)|ensembl:ENSRNOT00000025819(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|rcsb pdb:2DWZ|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:sMGdo51UJT7c6ngmxSDrYfLvkLc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q4FZT9	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640482|ensembl:ENSRNOP00000002358	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psmd2_rat(display_long)|uniprotkb:Psmd2(gene name)|psi-mi:Psmd2(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1305752|refseq:NP_001026809.1|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|ensembl:ENSRNOG00000001719(gene)|ensembl:ENSRNOT00000002358(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|mint:Q4FZT9|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:RLdXL5kvmBPO1OIhqHL/NoXaeCo10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P62193	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-357586|uniprotkb:P49014|uniprotkb:Q96AZ3|uniprotkb:Q03527|ensembl:ENSRNOP00000005329	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs4_rat(display_long)|uniprotkb:Psmc1(gene name)|psi-mi:Psmc1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	ensembl:ENSRNOG00000003951(gene)|ensembl:ENSRNOT00000005329(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-532668|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|rgd:621097|refseq:NP_476464.1	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q32PW9	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640462	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q32pw9_rat(display_long)|uniprotkb:Psmc6(gene name)|psi-mi:Psmc6(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	interpro:IPR032501|rgd:1308825|refseq:NP_001093979.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR027417|interpro:IPR035263|interpro:IPR041569	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:dhlnNdFVjXrHDz1pz0jolo9GQHw10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P62198	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-357761|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:P52915|ensembl:ENSRNOP00000013997	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs8_rat(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:708376|refseq:NP_112411.1|ensembl:ENSRNOG00000010038(gene)|ensembl:ENSRNOT00000013997(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-4641258|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8948751	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:D4ACQ8	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649825|ensembl:ENSRNOP00000002119|ensembl:ENSRNOP00000075597	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:d4acq8_rat(display_long)|uniprotkb:RGD1563888(gene name)|psi-mi:RGD1563888(display_short)|uniprotkb:RGD1563888_predicted(gene name synonym)|uniprotkb:rCG_58845(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	refseq:NP_001101782.1|refseq:XP_008766753.1|refseq:XP_008766754.1|rgd:1563888|ensembl:ENSRNOG00000001554(gene)|ensembl:ENSRNOT00000002119(transcript)|ensembl:ENSRNOT00000087665(transcript)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR009704(EURL)|refseq:XP_017453511.1|refseq:XP_017453512.1	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:iD8IFWPAveOtX09vDQwHbAhaw/c10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q498M4	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649831|ensembl:ENSRNOP00000011556	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:wdr5_rat(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1305159|refseq:NP_001034123.1|refseq:XP_006233893.1|ensembl:ENSRNOG00000008212(gene)|ensembl:ENSRNOT00000011556(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4QQE|reactome:R-RNO-3214841|reactome:R-RNO-3214847|reactome:R-RNO-3214858|reactome:R-RNO-8936459|reactome:R-RNO-8951664	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P06686	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649928|ensembl:ENSRNOP00000054947	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:at1a2_rat(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2168|refseq:NP_036637.1|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0040011"(locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06686|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0035725"(sodium ion transmembrane transport)|ensembl:ENSRNOG00000007290(gene)|ensembl:ENSRNOT00000058143(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q5XIV0	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649873|ensembl:ENSRNOP00000020401	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:tet5c_rat(display_long)|uniprotkb:Tent5c(gene name)|psi-mi:Tent5c(display_short)|uniprotkb:Fam46c(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1359446|refseq:NP_001014063.1|refseq:XP_006233100.1|ensembl:ENSRNOG00000015222(gene)|ensembl:ENSRNOT00000020401(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693)|go:"GO:0005737"(cytoplasm)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:+112VRve7W1qtDrNEbVBL4zgZic10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q7TQ71	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649852|ensembl:ENSRNOP00000039645	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q7tq71_rat(display_long)|uniprotkb:rCG_63178(orf name)|uniprotkb:LOC360933(gene name)|psi-mi:LOC360933(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1565933|refseq:NP_001041368.1|ensembl:ENSRNOG00000029734(gene)|ensembl:ENSRNOT00000048329(transcript)|interpro:IPR019265	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:GyngUjbk0KQINx/uffZNpRyLy2U10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P61765	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-1029097|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|ensembl:ENSRNOP00000021178	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:stxb1_rat(display_long)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)|uniprotkb:Unc18a(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:rbSec1(gene name synonym)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:3785|refseq:NP_037170.1|ensembl:ENSRNOG00000015420(gene)|ensembl:ENSRNOT00000021178(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61765|rcsb pdb:3C98|rcsb pdb:3PUJ|rcsb pdb:4JEH|rcsb pdb:4JEU|rcsb pdb:6LPC|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|refseq:XP_006234001.1|dip:DIP-766N	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:B1WC80	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649882|ensembl:ENSRNOP00000030463|ensembl:ENSRNOP00000070129	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:b1wc80_rat(display_long)|uniprotkb:Mab21l4(gene name)|psi-mi:Mab21l4(display_short)|uniprotkb:RGD1563692(gene name synonym)|uniprotkb:RGD1563692_predicted(gene name synonym)|uniprotkb:rCG_55497(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1563692|refseq:NP_001102781.1|refseq:XP_006245609.1|ensembl:ENSRNOG00000023557(gene)|ensembl:ENSRNOT00000038563(transcript)|ensembl:ENSRNOT00000087584(transcript)|interpro:IPR024809|interpro:IPR024810	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:SQQAd3rEd75g6Mj+mFpcAJiraKQ10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:E9PU17	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649964|uniprotkb:Q4H493|ensembl:ENSRNOP00000057544	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:abcah_rat(display_long)|uniprotkb:Abca17(gene name)|psi-mi:Abca17(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1560494|refseq:NP_001026807.1|refseq:XP_006245989.1|refseq:XP_006245990.1|ensembl:ENSRNOG00000039656(gene)|ensembl:ENSRNOT00000060818(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006638"(neutral lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR026082|interpro:IPR027417	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:gciexkQGmoYP5/OmQgYOvG/AQdM10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P31596	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2649895	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:eaa2_rat(display_long)|uniprotkb:Slc1a2(gene name)|psi-mi:Slc1a2(display_short)|uniprotkb:Eaat2(gene name synonym)|uniprotkb:Glt1(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 2(gene name synonym)|uniprotkb:GLT-1(gene name synonym)|uniprotkb:Solute carrier family 1 member 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	mint:P31596|rgd:3697|refseq:NP_058911.2|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|refseq:NP_001289018.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007399"(nervous system development)|go:"GO:0007632"(visual behavior)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031982"(vesicle)|go:"GO:0033229"(cysteine transmembrane transporter activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043200"(response to amino acid)|go:"GO:0044297"(cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|interpro:IPR036458	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:JednhWybRDznXCugAtjbnX/1JmM10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P07340	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P10719	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916266|uniprotkb:Q499W0	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:atpb_rat(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:621368|refseq:NP_599191.1|interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009631"(cold acclimation)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904643"(response to curcumin)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-1268020|reactome:R-RNO-163210|reactome:R-RNO-8949613|interpro:IPR027417|mint:P10719|interpro:IPR036121	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:K1RREEkTYSnEnU2leNpq3SCa3wc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q5FVG4	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640696|ensembl:ENSRNOP00000025240|ensembl:ENSRNOP00000051753|uniprotkb:D3ZRF5	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q5fvg4_rat(display_long)|uniprotkb:Slc25a22(gene name)|psi-mi:Slc25a22(display_short)|uniprotkb:LOC100911440(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:6492572|rgd:1307826|refseq:NP_001014049.1|ensembl:ENSRNOG00000018450(gene)|ensembl:ENSRNOG00000049944(gene)|ensembl:ENSRNOT00000025240(transcript)|ensembl:ENSRNOT00000054869(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR018108|interpro:IPR023395	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:ptfUjhJOG9qeqqxeJerOTm/PWmI10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q05962	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918169	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:adt1_rat(display_long)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:Slc25a4(gene name)|psi-mi:Slc25a4(display_short)|uniprotkb:Ant1(gene name synonym)|uniprotkb:Aac1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:620352|refseq:NP_445967.1|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:Q05962|go:"GO:0001889"(liver development)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|reactome:R-RNO-83936	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:NA6aO99oqoOE7rPf9y3s7zKx6HM10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q09073	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918254|ensembl:ENSRNOP00000015913	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:adt2_rat(display_long)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:620353|refseq:NP_476443.1|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:Q09073|reactome:R-RNO-83936|go:"GO:0005471"("ATP:ADP antiporter activity")|ensembl:ENSRNOG00000039980(gene)|ensembl:ENSRNOT00000015085(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:WdaA9kTxHaJrlP00OIJCP15jMpI10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q6PCT9	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-919152|ensembl:ENSRNOP00000009249	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q6pct9_rat(display_long)|uniprotkb:Psmd6(gene name)|psi-mi:Psmd6(display_short)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)|uniprotkb:rCG_42172(orf name)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:735127|refseq:NP_942025.1|ensembl:ENSRNOG00000006751(gene)|ensembl:ENSRNOT00000009249(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:eVII3KU7aJLNRx/HTFdmpajOw0o10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:Q5U2S7	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640515|ensembl:ENSRNOP00000037928	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:q5u2s7_rat(display_long)|uniprotkb:rCG_33694(orf name)|uniprotkb:Psmd3(gene name)|psi-mi:Psmd3(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640427|imex:IM-13769-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:1311470|refseq:NP_001008282.1|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-68949|ensembl:ENSRNOG00000028103(gene)|ensembl:ENSRNOT00000039836(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-1236978|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785	psi-mi:"MI:0469"(intact)	-	-	comment:"In GST-UBL eluates from Rat forebrain (P2 fraction), the highest number of peptides identified by MS corresponded to all 6 ATPase subunits and 11 of 14 non-ATPase subunits of the 19S proteasome. Several other proteins were also identified in GST-UBL precipitates with multiple peptide 'hits'."|figure legend:Table S1.|caution:"The participant EBI-919537(Q4QRB4) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2016/07/13	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:W5WYRKsyeK0tL+PgKEvV8YzHyWc10116	intact-crc:1BF6485AA290CF75|rigid:csM3oNVNW0W5GRp8bjIJ12mer1s	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q4KMA2	uniprotkb:P08413	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916155	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640814|imex:IM-13769-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1.|comment:CaMK2a was consistently present in the GST-UBL precipitate, whereas CaMK2b was detectable in half of the experiments.  CaMK2a and proteasome association was inhibited by addition of ATP.|antagonist:ATP|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	intact-crc:4A138E64BE3802C9|rigid:XU+fJXjgz8z84IykQ3W5OjFXWO0	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?|mutation decreasing interaction:8-8,45-45	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P11275	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640645	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640814|imex:IM-13769-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1.|comment:CaMK2a was consistently present in the GST-UBL precipitate, whereas CaMK2b was detectable in half of the experiments.  CaMK2a and proteasome association was inhibited by addition of ATP.|antagonist:ATP|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:4A138E64BE3802C9|rigid:XU+fJXjgz8z84IykQ3W5OjFXWO0	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?|mutation decreasing interaction:8-8,45-45	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P62198	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-357761|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:P52915|ensembl:ENSRNOP00000013997	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs8_rat(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640814|imex:IM-13769-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:708376|refseq:NP_112411.1|ensembl:ENSRNOG00000010038(gene)|ensembl:ENSRNOT00000013997(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-4641258|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8948751	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1.|comment:CaMK2a was consistently present in the GST-UBL precipitate, whereas CaMK2b was detectable in half of the experiments.  CaMK2a and proteasome association was inhibited by addition of ATP.|antagonist:ATP|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10116	intact-crc:4A138E64BE3802C9|rigid:XU+fJXjgz8z84IykQ3W5OjFXWO0	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?|mutation decreasing interaction:8-8,45-45	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:Q63347	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918567|uniprotkb:Q62690|uniprotkb:Q6P7R9	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs7_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640814|imex:IM-13769-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:3428|refseq:NP_150239.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|reactome:R-RNO-8932339|interpro:IPR027417|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035245|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1.|comment:CaMK2a was consistently present in the GST-UBL precipitate, whereas CaMK2b was detectable in half of the experiments.  CaMK2a and proteasome association was inhibited by addition of ATP.|antagonist:ATP|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mkLED0sa4m4p2Q/87z8Fe2h8J0410116	intact-crc:4A138E64BE3802C9|rigid:XU+fJXjgz8z84IykQ3W5OjFXWO0	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?|mutation decreasing interaction:8-8,45-45	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P48004	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-917581	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:psa7_rat(display_long)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640947|imex:IM-13769-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:61851|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-RNO-8932339|interpro:IPR029055|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035190|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168|rcsb pdb:6TU3|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0098794"(postsynapse)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig S1B.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:In4yx2CtUgSGzS6Bw+PMORHA4SY10116	intact-crc:BE8AD425163D1E54|rigid:k1t5mbLEH45TRealMY2BFcAA6Hw	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:Q63347	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-918567|uniprotkb:Q62690|uniprotkb:Q6P7R9	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs7_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640947|imex:IM-13769-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:3428|refseq:NP_150239.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|reactome:R-RNO-8932339|interpro:IPR027417|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035245|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig S1B.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mkLED0sa4m4p2Q/87z8Fe2h8J0410116	intact-crc:BE8AD425163D1E54|rigid:k1t5mbLEH45TRealMY2BFcAA6Hw	false	binding-associated region:1..1-79..79(IPR000626)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P08413	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-916155	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2642399|imex:IM-13769-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 5C, 5D.|comment:Stimulating CaMKII phosphorylation on T286/T287 increased  2- to 3-fold the amount of endogenous CAMK2a and CAMK2b precipitated by UBL-GST beads.|agonist:"Calcium/calmodulin and ATP (to enhance CaMKII autophosphorylation on T286/T287)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	intact-crc:A26CABF38FB28368|rigid:mnvBAmV9TU9hDq2yCP8pXoy0Q9Q	false	glutathione s tranferase tag:?-?|binding-associated region:1..1-79..79(IPR000626)	O-phospho-L-threonine:287-287	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P62198	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-357761|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:P52915|ensembl:ENSRNOP00000013997	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:prs8_rat(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2642399|imex:IM-13769-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:708376|refseq:NP_112411.1|ensembl:ENSRNOG00000010038(gene)|ensembl:ENSRNOT00000013997(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-4641258|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8948751	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 5C, 5D.|comment:Stimulating CaMKII phosphorylation on T286/T287 increased  2- to 3-fold the amount of endogenous CAMK2a and CAMK2b precipitated by UBL-GST beads.|agonist:"Calcium/calmodulin and ATP (to enhance CaMKII autophosphorylation on T286/T287)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10116	intact-crc:A26CABF38FB28368|rigid:mnvBAmV9TU9hDq2yCP8pXoy0Q9Q	false	glutathione s tranferase tag:?-?|binding-associated region:1..1-79..79(IPR000626)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4KMA2	uniprotkb:P11275	intact:EBI-2640429|uniprotkb:Q0D2G8|uniprotkb:Q5CZZ8|uniprotkb:Q6IRD5|ensembl:ENSRNOP00000021629	intact:EBI-2640645	psi-mi:rd23b_rat(display_long)|uniprotkb:Rad23b(gene name)|psi-mi:Rad23b(display_short)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0096"(pull down)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2642399|imex:IM-13769-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1562958|refseq:NP_001020446.1|ensembl:ENSRNOG00000016137(gene)|ensembl:ENSRNOT00000021629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|reactome:R-RNO-532668|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5689877	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 5C, 5D.|comment:Stimulating CaMKII phosphorylation on T286/T287 increased  2- to 3-fold the amount of endogenous CAMK2a and CAMK2b precipitated by UBL-GST beads.|agonist:"Calcium/calmodulin and ATP (to enhance CaMKII autophosphorylation on T286/T287)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/13	2014/10/16	rogid:w/UpqxEU7/W0bGU+wOEcNY82q6s10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:A26CABF38FB28368|rigid:mnvBAmV9TU9hDq2yCP8pXoy0Q9Q	false	glutathione s tranferase tag:?-?|binding-associated region:1..1-79..79(IPR000626)	O-phospho-L-threonine:286-286	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62198	uniprotkb:P11275	intact:EBI-357761|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:P52915|ensembl:ENSRNOP00000013997	intact:EBI-2640645	psi-mi:prs8_rat(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640838|imex:IM-13769-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708376|refseq:NP_112411.1|ensembl:ENSRNOG00000010038(gene)|ensembl:ENSRNOT00000013997(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-4641258|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8948751	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1F.|comment:"Immunoprecipitation (IP) of proteasomes from P2 lysates with Rpt6 antibody co-IPed CaMK2a."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:05C604F906FAB9FD|rigid:Mcqdh69J6BWVeER7TLgsOpHEqpM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63570	uniprotkb:P11275	intact:EBI-918637|ensembl:ENSRNOP00000025819	intact:EBI-2640645	psi-mi:prs6b_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:Psmc4(gene name)|psi-mi:Psmc4(display_short)|uniprotkb:Tbp7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2640898|imex:IM-13769-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621102|refseq:NP_476463.1|ensembl:ENSRNOG00000018994(gene)|ensembl:ENSRNOT00000025819(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|rcsb pdb:2DWZ|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	go:"GO:0030425"(dendrite)|go:"GO:0000502"(proteasome complex)	-	-	figure legend:Fig 1G, S1C.|comment:CaMK2a shows real and significant colocalization with proteasomes in neuronal dendrites.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:sMGdo51UJT7c6ngmxSDrYfLvkLc10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:5EB96C908FCEB92B|rigid:kdeYxp/xGLBMiH8aOVrvJ+xJqx8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P11275	uniprotkb:Q63570	intact:EBI-2640645	intact:EBI-918637|ensembl:ENSRNOP00000025819	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:prs6b_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:Psmc4(gene name)|psi-mi:Psmc4(display_short)|uniprotkb:Tbp7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2641343|imex:IM-13769-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	rgd:621102|refseq:NP_476463.1|ensembl:ENSRNOG00000018994(gene)|ensembl:ENSRNOT00000025819(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|rcsb pdb:2DWZ|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	go:"GO:0000502"(proteasome complex)|go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig 4E.|comment:In neurons expressing PSD-95-FKBP and CaMK2A-mCherry-FRB, rapamycin induced a 60% increase in the amount of Rpt3 signal that colocalized with PSD-95. This result was confirmed with immunostaining for another endogenous proteasome subunit, Rpt2.|agonist:"rapamycin (to induce FKBP and FRB binding) and tetrodotoxin (a neurotoxin)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	rogid:sMGdo51UJT7c6ngmxSDrYfLvkLc10116	intact-crc:7E9CD4472C47767F|rigid:kdeYxp/xGLBMiH8aOVrvJ+xJqx8	false	fluorescent protein tag:?-?|fusion protein:?-?	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P62193	uniprotkb:P11275	intact:EBI-357586|uniprotkb:P49014|uniprotkb:Q96AZ3|uniprotkb:Q03527|ensembl:ENSRNOP00000005329	intact:EBI-2640645	psi-mi:prs4_rat(display_long)|uniprotkb:Psmc1(gene name)|psi-mi:Psmc1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2641353|imex:IM-13769-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000003951(gene)|ensembl:ENSRNOT00000005329(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-532668|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168|rgd:621097|refseq:NP_476464.1	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	go:"GO:0014069"(postsynaptic density)|go:"GO:0000502"(proteasome complex)	-	-	figure legend:Fig S4A.|comment:In neurons expressing PSD-95-FKBP and CaMK2A-mCherry-FRB, rapamycin induced a 60% increase in the amount of Rpt3 signal that colocalized with PSD-95. This result was confirmed with immunostaining for another endogenous proteasome subunit, Rpt2.|agonist:"rapamycin (to induce FKBP and FRB binding) and tetrodotoxin (a neurotoxin)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:50AD1440F91B2977|rigid:g26HtFX1YsiO4jch14cWA9uBrLc	false	-	fusion protein:?-?|fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q63570	uniprotkb:P11275	intact:EBI-918637|ensembl:ENSRNOP00000025819	intact:EBI-2640645	psi-mi:prs6b_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:Psmc4(gene name)|psi-mi:Psmc4(display_short)|uniprotkb:Tbp7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643108|imex:IM-13769-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621102|refseq:NP_476463.1|ensembl:ENSRNOG00000018994(gene)|ensembl:ENSRNOT00000025819(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|rcsb pdb:2DWZ|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-983168	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	go:"GO:0043197"(dendritic spine)	-	-	figure legend:Fig S5C, S5D.|comment:Overexpression of either CaMK2A-T286D or the kinase-dead double mutant CaMK2A-T286D/K42R was more effective than wild-type CaMK2A in boosting the concentration of endogenous proteasomes in spines.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:sMGdo51UJT7c6ngmxSDrYfLvkLc10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:6F658CF00225DE06|rigid:kdeYxp/xGLBMiH8aOVrvJ+xJqx8	false	-	flag tag:?-?|mutation increasing interaction:286-286|mutation increasing interaction:286-286,42-42	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P62195	uniprotkb:P11275	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-2640645	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2642383|imex:IM-13769-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:Fig 5A, 5B.|comment:"When transfected into HEK293 cells, wild-type Flag-tagged CaMK2a interacted weakly but significantly with endogenous proteasomes. Five times more Rpt6 was coimmunoprecipitated with CaMK2A-T286D, a mutant that mimics autophosphorylation on Thr-286 and renders the enzyme calcium-calmodulin-independent and constitutively active. A kinase-dead CaMK2a double mutant (CaMK2a-T286D/K42R) showed association with the proteasome similar to CaMK2a-T286D."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:71BB1CB6B88EF5FC|rigid:Bjsxo6/KzEthr3y3LabQ+ZNGciA	false	-	flag tag:?-?|mutation increasing interaction:286-286|mutation increasing interaction:286-286,42-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62195	uniprotkb:P11275	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-2640645	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643073|imex:IM-13769-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:Fig 5G, 5H.|comment:Proteasomes were associated  more with CaMK2a homomers than with a/b heteromers.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:63F440DF345D95FB|rigid:Bjsxo6/KzEthr3y3LabQ+ZNGciA	false	-	flag tag:?-?|mutation increasing interaction:286-286,42-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62195	uniprotkb:P08413	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-916155	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643094|imex:IM-13769-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:Fig S5A, S5B.|comment:CaMKI2B mutants behaved similarly in this proteasome coimmunoprecipitation assay, however, the differences in the binding were smaller and less robust than seen with CaMK2A mutants.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	intact-crc:74DA8D3FA4A78964|rigid:BQwUEFz1yMXBIIHfM87ewE2oxJw	false	-	mutation increasing interaction:287-287|flag tag:?-?|mutation increasing interaction:287-287,43-43|mutation increasing interaction:43-43	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62195	uniprotkb:P11275	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-2640645	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643125|imex:IM-13769-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:6C, 6D.|agonist:calcium and calmodulin.|comment:"Calcium/calmodulin added to the cell lysate stimulated the association of CaMK2A-T286A with Rpt6 three fold,  but phospho-mimic CaMK2A-T286D still bound more Rpt6 than calcium/calmodulin-treated CaMK2A-T286A). Thus, CaMK2A-T286A could partially support proteasome redistribution due to activation by calcium/calmodulin."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:7633D783EA179BDB|rigid:Bjsxo6/KzEthr3y3LabQ+ZNGciA	false	-	flag tag:?-?|mutation increasing interaction:286-286|mutation:286-286	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08413	uniprotkb:P62195	intact:EBI-916155	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2650106|imex:IM-13769-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	psi-mi:"MI:0469"(intact)	-	crc64:29C6410C4A85A7F7	figure legend:Fig 5G, 5H.|comment:Proteasomes were associated  more with CaMK2a homomers than with a/b heteromers.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	intact-crc:AB1C977BB7FD571F|rigid:BQwUEFz1yMXBIIHfM87ewE2oxJw	false	flag tag:?-?|mutation:287-287,43-43	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62195	uniprotkb:P08413	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-916155	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2642446|imex:IM-13769-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:Fig 5E, 5F.|comment:CaMK2a-T286D/K42R associates with Rpt6 more than CaMK2b-T287D/K43R.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	intact-crc:C5938FF94282A3B8|rigid:BQwUEFz1yMXBIIHfM87ewE2oxJw	false	-	flag tag:?-?|mutation:287-287,43-43	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62195	uniprotkb:P11275	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	intact:EBI-2640645	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2650676|imex:IM-13769-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	psi-mi:"MI:0469"(intact)	crc64:29C6410C4A85A7F7	-	figure legend:Fig 5E, 5F.|comment:CaMK2a-T286D/K42R associates with Rpt6 more than CaMK2b-T287D/K43R.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/04/13	2014/10/16	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:29758AC284DF3441|rigid:Bjsxo6/KzEthr3y3LabQ+ZNGciA	false	-	flag tag:?-?|mutation increasing interaction:286-286,42-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63347	uniprotkb:P11275	intact:EBI-918567|uniprotkb:Q62690|uniprotkb:Q6P7R9	intact:EBI-2640645	psi-mi:prs7_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643141|imex:IM-13769-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3428|refseq:NP_150239.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|reactome:R-RNO-8932339|interpro:IPR027417|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035245|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	go:"GO:0043197"(dendritic spine)	-	-	figure legend:S6|comment:NMDA-induced Rpt1-GFP redistribution relies on CaMK2A that can translocate to spines, but not the kinase activity of the enzyme.|agonist:NMDA|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:mkLED0sa4m4p2Q/87z8Fe2h8J0410116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:80DAD7EFCE11CF26|rigid:Im4lD3sbPsByMQpPsUnXU4K0Rd0	false	green fluorescent protein tag:?-?	flag tag:?-?|mutation:286-286	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q63347	uniprotkb:P11275	intact:EBI-918567|uniprotkb:Q62690|uniprotkb:Q6P7R9	intact:EBI-2640645	psi-mi:prs7_rat(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0051"(fluorescence technology)	Bingol et al. (2010)	imex:IM-13769|pubmed:20178748	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2643172|imex:IM-13769-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3428|refseq:NP_150239.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|reactome:R-RNO-8932339|interpro:IPR027417|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|interpro:IPR035245|interpro:IPR041569|reactome:R-RNO-174084|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-8951664|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|reactome:R-RNO-983168	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	go:"GO:0043197"(dendritic spine)	-	-	figure legend:S2E, S2F.|comment:CaMK2A stabilizes proteasomes in spines, leading to proteasome accumulation following NMDA stimulation.|agonist:NMDA|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2010/04/13	2014/10/16	rogid:mkLED0sa4m4p2Q/87z8Fe2h8J0410116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	intact-crc:BED26DCDAC72AB8C|rigid:Im4lD3sbPsByMQpPsUnXU4K0Rd0	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)