#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P24161 uniprotkb:P62991 intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2010) pubmed:20150895|imex:IM-15082|mint:MINT-7895642|doi:10.1038/emboj.2010.10 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803421|mint:MINT-7895679|imex:IM-15082-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-7895681(identity) interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K|mint:MINT-7895682(identity) - comment:mint - comment:mint|figure legend:f1a f1d f1f f2e f3d f5b fs4 fs5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell) - 2010/05/20 2014/10/16 rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:9250AF076D02D42A|rigid:1w1pDh4avwXvPj8q+wrbPMuPeH0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P22646 uniprotkb:P62991 intact:EBI-7803432|ensembl:ENSMUSP00000099896|intact:MINT-7895702 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:cd3e_mouse(display_long)|uniprotkb:Cd3e(gene name)|psi-mi:Cd3e(display_short)|uniprotkb:T-cell surface antigen T3/Leu-4 epsilon chain(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2010) pubmed:20150895|imex:IM-15082|mint:MINT-7895642|doi:10.1038/emboj.2010.10 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803469|mint:MINT-7895735|imex:IM-15082-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR036179|mint:P22646|rcsb pdb:1JBJ|rcsb pdb:1XMW|rcsb pdb:2K4F|rcsb pdb:3R08|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-389948|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|ensembl:ENSMUSG00000032093(gene)|ensembl:ENSMUST00000102832(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044297"(cell body)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046649"(lymphocyte activation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|refseq:NP_031674.1|refseq:XP_006510029.1|mint:MINT-7895737(identity) interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K|mint:MINT-7895739(identity) - comment:mint - figure legend:f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell) - 2010/05/20 2014/10/16 rogid:pCHLuaLDHcsqdyl6Cc0NjIH+4xA10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:CA701644DC5CF40F|rigid:04oBYnK9TxfLN/gFCv0jv8GzRvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P06332 uniprotkb:P01731 intact:EBI-1404|ensembl:ENSMUSP00000024044 intact:EBI-1433|ensembl:ENSMUSP00000068123 psi-mi:cd4_mouse(display_long)|uniprotkb:Cd4(gene name)|psi-mi:Cd4(display_short)|uniprotkb:T-cell surface antigen T4/Leu-3(gene name synonym)|uniprotkb:T-cell differentiation antigen L3T4(gene name synonym) psi-mi:cd8a_mouse(display_long)|uniprotkb:Cd8a(gene name)|psi-mi:Cd8a(display_short)|uniprotkb:Lyt-2(gene name synonym)|uniprotkb:Lyt2(gene name synonym)|uniprotkb:T-cell surface glycoprotein Lyt-2(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Wang et al. (2010) pubmed:20150895|imex:IM-15082|mint:MINT-7895642|doi:10.1038/emboj.2010.10 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7803506|mint:MINT-7895789|imex:IM-15082-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038516.1|ensembl:ENSMUSG00000023274(gene)|ensembl:ENSMUST00000024044(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006948"(induction by virus of host cell-cell fusion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035397"(helper T cell enhancement of adaptive immune response)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042011"(interleukin-16 binding)|go:"GO:0042012"(interleukin-16 receptor activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045058"(T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000973(T-cell surface antigen CD4)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015274(CD4, extracellular)|interpro:IPR021963|interpro:IPR036179|mint:P06332|reactome:R-MMU-1462054|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-389948|reactome:R-MMU-449836|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-7895792(identity) refseq:NP_001074579.1|ensembl:ENSMUSG00000053977(gene)|ensembl:ENSMUST00000066747(transcript)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023024"(MHC class I protein complex binding)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045065"(cytotoxic T cell differentiation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051607"(defense response to virus)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015468(CD8 alpha chain)|interpro:IPR036179|mint:P01731|rcsb pdb:1BQH|rcsb pdb:1NEZ|rcsb pdb:2ARJ|rcsb pdb:2ATP|rcsb pdb:3B9K|rcsb pdb:3DMM|reactome:R-MMU-198933|mint:MINT-7895791(identity) go:"GO:0005886"(plasma membrane) - - comment:homomint|comment:mint|figure legend:f2b f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell) - 2010/05/20 2014/10/16 rogid:80TDw5kSJXFKGKJpjZ7Rdb9gD1g10090 rogid:YKyIbIVRaV5JMryX8MRe8C5SH9M10090 intact-crc:22AC798BBB59CB64|rigid:Hd2/sMxC/FmqKcX6fm1g5dt+j/I false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P24161 uniprotkb:Q61168 intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3 intact:EBI-911973|uniprotkb:Q60923|ensembl:ENSMUSP00000118415 psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym) psi-mi:lapm5_mouse(display_long)|uniprotkb:Lysosomal-associated multitransmembrane protein 5(gene name synonym)|uniprotkb:Retinoic acid-inducible E3 protein(gene name synonym)|uniprotkb:Laptm5(gene name)|psi-mi:Laptm5(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Wang et al. (2010) pubmed:20150895|imex:IM-15082|mint:MINT-7895642|doi:10.1038/emboj.2010.10 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7803528|mint:MINT-7895824|imex:IM-15082-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-7895827(identity) ensembl:ENSMUSG00000028581(gene)|ensembl:ENSMUST00000151698(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0012502"(induction of programmed cell death)|refseq:NP_034816.1|refseq:XP_017175490.1|dip:DIP-37698N|go:"GO:0019899"(enzyme binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:0140311"(protein sequestering activity)|go:"GO:0140646"(negative regulation of pre-B cell receptor expression)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1904093"(negative regulation of autophagic cell death)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR004687(Golgi 4-transmembrane spanning transporter)|interpro:IPR018396|interpro:IPR018397|mint:Q61168|mint:MINT-7895826(identity) go:"GO:0005634"(nucleus) comment:mint - comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell) - 2010/05/20 2014/10/16 rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090 rogid:X9DgC9FAmYf+Bom4kCAGi1rgTLQ10090 intact-crc:840E586F2AEB3B9D|rigid:jAVvPl/f+brTg+BUUsnZJA2G7gc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)