#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0CG48 uniprotkb:Q92783 intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short) psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801701|mint:MINT-7896409|imex:IM-15105-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3|mint:MINT-7896411(identity) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896412(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:t1 f1a f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/26 2014/10/16 rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 intact-crc:9AC652DD66D28CF4|rigid:HNaLdFsdiNlsUz+44YrW6sMTaRs false - binding-associated region:2-143(MINT-7896420) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92783 uniprotkb:P0CG53 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801745|mint:MINT-7896423|imex:IM-15105-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896427(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896425(identity) - - - comment:domino|comment:mint|figure legend:t2 f1d f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:220.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:9D02EA1B342C81AD|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false glutathione s tranferase tag:?-?(MINT-7896444)|binding-associated region:2-143(MINT-7896428)|mutation disrupting interaction:26-26(MINT-7896468) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92783 uniprotkb:P0CG53 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801769|mint:MINT-7896447|imex:IM-15105-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896452(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896450(identity) - - - comment:domino|comment:mint|figure legend:t2 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:350.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:F9489C9728E29E05|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false binding-associated region:2-143(MINT-7896455)|mutation increasing interaction:31-31(MINT-7896462) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92783 uniprotkb:P0CG53 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801790|mint:MINT-7896471|imex:IM-15105-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896476(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896474(identity) - - - comment:domino|comment:mint|figure legend:t2 f1d f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:220.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:7C72E7114C894C84|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false glutathione s tranferase tag:?-?(MINT-7896479)|binding-associated region:2-143(MINT-7896481)|mutation disrupting interaction:30-30(MINT-7896477) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:Q92783 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801832|mint:MINT-7896489|imex:IM-15105-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896492(identity) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896494(identity) - - - comment:domino|comment:mint|figure legend:t2 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:400.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 intact-crc:ED39811E02ECDF3D|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false - mutation decreasing interaction:27-27(MINT-7896495)|glutathione s tranferase tag:?-?(MINT-7896500)|binding-associated region:2-143(MINT-7896497) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38753 uniprotkb:P0CG53 intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801864|mint:MINT-7896513|imex:IM-15105-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW|mint:MINT-7896518(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896516(identity) - crc64:026267836BBADF69 - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:190.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:3ADDF27403518262|rigid:k0a0FEftRdTU1uy6QiP2f3mc9uE false tag:?-?(MINT-7896522)|binding-associated region:1-146(MINT-7896519) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38753 uniprotkb:P0CG53 intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801927|mint:MINT-7896532|imex:IM-15105-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW|mint:MINT-7896537(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896535(identity) - crc64:026267836BBADF69 - figure legend:t2|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:490.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:C002EBDFD4E5A37E|rigid:k0a0FEftRdTU1uy6QiP2f3mc9uE false mutation disrupting interaction:170-170(MINT-7896546)|binding-associated region:161-182(MINT-7896540)|mutation disrupting interaction:174-174(MINT-7896549)|tag:?-?(MINT-7896538) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14964 uniprotkb:P0CG53 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7801981|mint:MINT-7896554|imex:IM-15105-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7896559(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896557(identity) - - - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1400.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:C82A45267958BCBD|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false binding-associated region:2-143(MINT-7896562)|tag:?-?(MINT-7896560) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40343 uniprotkb:P0CG53 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802001|mint:MINT-7896569|imex:IM-15105-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7896574(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896572(identity) - crc64:76C4501B0EBC9C84 - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1500.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:2F0C116347CD853E|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false binding-associated region:2-150(MINT-7896575)|tag:?-?(MINT-7896578) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:P40343 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802067|mint:MINT-7896605|imex:IM-15105-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896608(identity) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7896610(identity) - - crc64:76C4501B0EBC9C84 figure legend:t2|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:360.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:820C15F7C9D1EEB5|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false - tag:?-?(MINT-7896618)|binding-associated region:301-320(MINT-7896615) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92783 uniprotkb:P0CG53 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802087|mint:MINT-7896624|imex:IM-15105-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896629(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896627(identity) - - - figure legend:t2|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:430.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:A6D2CAF2FD92B8F9|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false binding-associated region:158-200(MINT-7896632) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:P40343 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802039|mint:MINT-7896584|imex:IM-15105-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896587(identity) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7896589(identity) - - crc64:76C4501B0EBC9C84 figure legend:t2|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:600.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:1A45BA9E5D7FF458|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false - binding-associated region:258-277(MINT-7896592)|mutation disrupting interaction:270-270(MINT-7896601)|tag:?-?(MINT-7896590)|mutation disrupting interaction:266-266(MINT-7896598) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ52 uniprotkb:P0CG53 intact:EBI-447404|uniprotkb:Q15017|uniprotkb:Q6IS16|uniprotkb:Q9UJY3|uniprotkb:B7Z7E2|uniprotkb:B7Z7M9|uniprotkb:J3KRN0|intact:EBI-28988067|ensembl:ENSP00000438085|ensembl:ENSP00000496890 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:gga3_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 3(gene name synonym)|uniprotkb:GGA3(gene name)|psi-mi:GGA3(display_short)|uniprotkb:KIAA0154(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802104|mint:MINT-7896642|imex:IM-15105-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278570.1|refseq:NP_001278571.1|refseq:NP_001166174.1|refseq:NP_054720.1|refseq:NP_619525.1|ensembl:ENST00000538886|ensembl:ENSP00000446421|ensembl:ENST00000578348|ensembl:ENSP00000463288|ensembl:ENST00000582717|ensembl:ENSP00000462081|ensembl:ENSP00000496890|ensembl:ENSP00000438085|refseq:NP_001166175.1|dip:DIP-31600N|ensembl:ENSG00000125447(gene)|ensembl:ENST00000537686(transcript)|ensembl:ENST00000649398(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR002014(VHS)|interpro:IPR044111|mint:Q9NZ52|rcsb pdb:1JPL|rcsb pdb:1JUQ|rcsb pdb:1LF8|rcsb pdb:1P4U|rcsb pdb:1WR6|rcsb pdb:1YD8|reactome:R-HSA-8854214|reactome:R-HSA-8875656|reactome:R-HSA-977225|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR027422|interpro:IPR038425|interpro:IPR041198|mint:MINT-7896647(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896645(identity) - - - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2100.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:MuqZi22xY1lyDboND7/xRNCqJbc9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:4A04550D00C6C6C2|rigid:GCjoOc6Uxs1nlFG5QpuxAWuB0Ns false binding-associated region:1-147(MINT-7896650)|tag:?-?(MINT-7896648) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:Q06336 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-7563|uniprotkb:D6VSY7|ensemblfungi:YDR358W psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:gga1_yeast(display_long)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)|uniprotkb:YDR358W(locus name)|uniprotkb:D9476.2(orf name)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802124|mint:MINT-7896657|imex:IM-15105-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896660(identity) refseq:NP_010645.1|sgd:S000002766|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR004152(GAT)|interpro:IPR002014(VHS)|interpro:IPR041198|mint:Q06336|interpro:IPR038425|ensemblfungi:YDR358W(gene)|ensemblfungi:YDR358W_mRNA(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|rcsb pdb:5CN1|rcsb pdb:5CN2|mint:MINT-7896662(identity) - - - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:450.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:amRjpUy8HGQDzBbSbnu+BweyeAs559292 intact-crc:F96FB08A3BE8789A|rigid:yajAs/yFlNaBJVzzn5iRh1ADp3c false - binding-associated region:1-165(MINT-7896665)|tag:?-?(MINT-7896663) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:O75674 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-712991|intact:EBI-28969677|ensembl:ENSP00000460823|uniprotkb:Q53G06|uniprotkb:Q8N749|uniprotkb:B7Z9E2 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:tm1l1_human(display_long)|uniprotkb:Target of Myb-like protein 1(gene name synonym)|uniprotkb:Src-activating and signaling molecule protein(gene name synonym)|uniprotkb:TOM1L1(gene name)|psi-mi:TOM1L1(display_short)|uniprotkb:SRCASM(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802181|mint:MINT-7896687|imex:IM-15105-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896690(identity) ensembl:ENSG00000141198(gene)|ensembl:ENST00000575882(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR027428|mint:O75674|rcsb pdb:3RRU|interpro:IPR038425|refseq:NP_005477.2|ensembl:ENST00000348161|ensembl:ENSP00000343901|ensembl:ENST00000536554|ensembl:ENSP00000443099|ensembl:ENST00000570371|ensembl:ENSP00000458553|ensembl:ENST00000575333|ensembl:ENSP00000458918|ensembl:ENSP00000460823|refseq:NP_001308102.1|refseq:NP_001308103.1|refseq:NP_001308104.1|refseq:NP_001308105.1|refseq:XP_016879491.1|mint:MINT-7896692(identity) - - - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:950.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:JQewIcPaPAlc2CknMG3p45OWbhI9606 intact-crc:1B518A68BB4718CD|rigid:h/ogVTXKN6QzISyjAdTqjZXXWQ8 false - binding-associated region:1-154(MINT-7896695)|tag:?-?(MINT-7896693) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60784 uniprotkb:P0CG53 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802144|mint:MINT-7896672|imex:IM-15105-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-7896677(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896675(identity) - - - comment:domino|comment:mint|figure legend:t2 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:440.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:DA277E2D49914AB9|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false tag:?-?(MINT-7896681)|binding-associated region:1-152(MINT-7896678) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:Q92783 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802201|mint:MINT-7896705|imex:IM-15105-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896708(identity) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7896710(identity) - - - comment:mint|figure legend:t2 f4b sf2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:310.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 intact-crc:F84B33895AC0B833|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false N6-glycyl-L-lysine:48-48(MINT-7898342) binding-associated region:2-200(MINT-7896713) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:P40343 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802220|mint:MINT-7896721|imex:IM-15105-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896724(identity) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7896726(identity) - - crc64:76C4501B0EBC9C84 comment:mint|figure legend:t2 sf2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:350.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:F2BA903CB01D8033|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false - tag:?-?(MINT-7896727)|binding-associated region:258-320(MINT-7896729) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:O14964 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802238|mint:MINT-7896737|imex:IM-15105-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896740(identity) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7896742(identity) - - - comment:domino|comment:mint|figure legend:t2 f4c sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:190.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:E5F3825B0200508E|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false N6-glycyl-L-lysine:63-63(MINT-7898374) tag:?-?(MINT-7896746)|binding-associated region:250-289(MINT-7896743) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14964 uniprotkb:P0CG53 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802262|mint:MINT-7896755|imex:IM-15105-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7896760(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7896758(identity) - - - comment:mint|figure legend:t2 f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:830.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:C9C74619D59BD5D2|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false tag:?-?(MINT-7896761)|binding-associated region:15-277(MINT-7896763) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92783 uniprotkb:P0CG53 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802298|mint:MINT-7898332|imex:IM-15105-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7898337(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898335(identity) - - - comment:mint|figure legend:t2 f4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:320.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:F7FE42EC5B429729|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false binding-associated region:2-200(MINT-7898338) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:Q92783 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802313|mint:MINT-7898346|imex:IM-15105-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898349(identity) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7898353(identity) - - - comment:mint|figure legend:t2 f4b sf2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:76.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 intact-crc:148AE8C5C31B75B6|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false N6-glycyl-L-lysine:63-63(MINT-7898350) binding-associated region:2-200(MINT-7898354) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14964 uniprotkb:P0CG53 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802332|mint:MINT-7898360|imex:IM-15105-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7898365(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898363(identity) - - - comment:domino|comment:mint|figure legend:t2 f4c sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:450.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:80D23B45385954E1|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false tag:?-?(MINT-7898366)|binding-associated region:250-289(MINT-7898368) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14964 uniprotkb:P0CG53 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802352|mint:MINT-7898377|imex:IM-15105-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7898384(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898380(identity) - - - comment:domino|comment:mint|figure legend:t2 f4c sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:820.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:BD927A55598F5823|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false tag:?-?(MINT-7898385)|binding-associated region:250-289(MINT-7898387) N6-glycyl-L-lysine:48-48(MINT-7898381) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:O14964 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802415|mint:MINT-7898409|imex:IM-15105-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898412(identity) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7898416(identity) - - - comment:mint|figure legend:t2 f4c sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:978.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:4D84FEE057D25CB3|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false N6-glycyl-L-lysine:48-48(MINT-7898413) binding-associated region:15-277(MINT-7898419)|tag:?-?(MINT-7898417) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14964 uniprotkb:P0CG53 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802393|mint:MINT-7898393|imex:IM-15105-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|mint:MINT-7898398(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898396(identity) - - - comment:mint|figure legend:t2 f4c fs2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:206.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:900EAB76C181342D|rigid:8u+uRwsnFz/G56KwAUwgWeO83UU false binding-associated region:15-277(MINT-7898399)|tag:?-?(MINT-7898401) N6-glycyl-L-lysine:63-63(MINT-7898406) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:P40343 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802437|mint:MINT-7898425|imex:IM-15105-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898428(identity) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7898430(identity) - - crc64:76C4501B0EBC9C84 comment:mint|figure legend:t2 sf2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:70.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:9C1D109188A6C071|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false N6-glycyl-L-lysine:63-63(MINT-7898437) tag:?-?(MINT-7898433)|binding-associated region:258-320(MINT-7898431) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40343 uniprotkb:P0CG53 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802459|mint:MINT-7898440|imex:IM-15105-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-7898447(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898443(identity) - crc64:76C4501B0EBC9C84 - comment:mint|figure legend:t2 sf2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:180.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:B83B86C2E17D5655|rigid:csEg/VsBIxqWnqF5qvsSyfe1i8I false binding-associated region:258-320(MINT-7898450)|tag:?-?(MINT-7898448) N6-glycyl-L-lysine:48-48(MINT-7898444) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CG53 uniprotkb:Q92783 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2010) pubmed:20150893|imex:IM-15105|mint:MINT-7896401|doi:10.1038/emboj.2010.6 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802481|mint:MINT-7898472|imex:IM-15105-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-7898475(identity) refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7898477(identity) - - - comment:domino|comment:mint|figure legend:t2 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:400.0x10^-6(molar) 2010/05/26 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606 intact-crc:E9C73D527614BDA4|rigid:v8hE23mKtiOMmjILSYDvhlNS3Iw false - binding-associated region:2-143(MINT-7898478)|mutation disrupting interaction:30-30(MINT-7898481) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)