#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51805 uniprotkb:O75081 intact:EBI-7135904|ensembl:ENSP00000358696|uniprotkb:Q5HY36|intact:MINT-7556947 intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679 psi-mi:plxa3_human(display_long)|uniprotkb:PLXNA3(gene name)|psi-mi:PLXNA3(display_short)|uniprotkb:PLXN4(gene name synonym)|uniprotkb:SEX(gene name synonym)|uniprotkb:Plexin-4(gene name synonym)|uniprotkb:Semaphorin receptor SEX(gene name synonym) psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fiedler et al. (2010) pubmed:20138877|imex:IM-15640|mint:MINT-7556939|doi:10.1016/j.febslet.2010.02.007|mint:d-10-00053 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7794502|mint:MINT-7556975|imex:IM-15640-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130827(gene)|ensembl:ENST00000369682(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1990138"(neuron projection extension)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_059984.3|dip:DIP-57386N|mint:MINT-7556977(identity) refseq:NP_005178.4|refseq:NP_787127.1|ensembl:ENSP00000268679|ensembl:ENST00000327483|ensembl:ENSP00000332122|dip:DIP-48898N|ensembl:ENSG00000129993(gene)|ensembl:ENST00000268679(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292("Myeloid transforming gene on chromosome 16 (MTG16)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081|mint:MINT-7556978(identity) - comment:mint|comment:homomint - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/02/01 2014/10/16 rogid:XHm0ijYaG0j8tgLPUILBSkUVN6E9606 rogid:YMP60LeA62hg4mNz15o70E/PqwE9606 intact-crc:CEA35403463B410C|rigid:RwHi8bBqOSVaYW+mPwcOgyx0BA4 false tag:?-?(MINT-7556985) tandem tag:?-?(MINT-7556980) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75081 uniprotkb:Q9DBC7 intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679 intact:EBI-645677|uniprotkb:Q3UKU7|uniprotkb:Q9JHR5|uniprotkb:Q9JHR6|ensembl:ENSMUSP00000056500|ensembl:ENSMUSP00000102288 psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short) psi-mi:kap0_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fiedler et al. (2010) pubmed:20138877|imex:IM-15640|mint:MINT-7556939|doi:10.1016/j.febslet.2010.02.007|mint:d-10-00053 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7794530|mint:MINT-7557008|imex:IM-15640-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005178.4|refseq:NP_787127.1|ensembl:ENSP00000268679|ensembl:ENST00000327483|ensembl:ENSP00000332122|dip:DIP-48898N|ensembl:ENSG00000129993(gene)|ensembl:ENST00000268679(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292("Myeloid transforming gene on chromosome 16 (MTG16)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081|mint:MINT-7557014(identity) refseq:NP_001300902.1|refseq:NP_001300903.1|refseq:NP_001300904.1|refseq:NP_001300905.1|refseq:NP_068680.1|refseq:XP_017169829.1|dip:DIP-32450N|ensembl:ENSMUSG00000020612(gene)|ensembl:ENSMUST00000049527(transcript)|ensembl:ENSMUST00000106677(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|reactome:R-MMU-983231|reactome:R-MMU-5610787|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q9DBC7|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|go:"GO:0043949"(regulation of cAMP-mediated signaling)|reactome:R-MMU-442720|mint:MINT-7557010(identity) - - - figure legend:f2a|comment:homomint|comment:mint|comment:"RI alpha has no uniprot update: it has been detected by mouse antibodies in COS7 cells, endougenously expressed."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/02/01 2014/10/16 rogid:YMP60LeA62hg4mNz15o70E/PqwE9606 rogid:0KqlQxZjK8QfS6VPEiTDtvHNTj410090 intact-crc:CE66A16D31D09AEC|rigid:XLoOPuG9N99JbtilH8oDVqjjK3A false tandem tag:?-?(MINT-7557015) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51805 uniprotkb:O75081 intact:EBI-7135904|ensembl:ENSP00000358696|uniprotkb:Q5HY36|intact:MINT-7556947 intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679 psi-mi:plxa3_human(display_long)|uniprotkb:PLXNA3(gene name)|psi-mi:PLXNA3(display_short)|uniprotkb:PLXN4(gene name synonym)|uniprotkb:SEX(gene name synonym)|uniprotkb:Plexin-4(gene name synonym)|uniprotkb:Semaphorin receptor SEX(gene name synonym) psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short) psi-mi:"MI:0096"(pull down) Fiedler et al. (2010) pubmed:20138877|imex:IM-15640|mint:MINT-7556939|doi:10.1016/j.febslet.2010.02.007|mint:d-10-00053 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7794574|mint:MINT-7556989|imex:IM-15640-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130827(gene)|ensembl:ENST00000369682(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1990138"(neuron projection extension)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_059984.3|dip:DIP-57386N|mint:MINT-7556995(identity) refseq:NP_005178.4|refseq:NP_787127.1|ensembl:ENSP00000268679|ensembl:ENST00000327483|ensembl:ENSP00000332122|dip:DIP-48898N|ensembl:ENSG00000129993(gene)|ensembl:ENST00000268679(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292("Myeloid transforming gene on chromosome 16 (MTG16)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081|mint:MINT-7556991(identity) - comment:mint|comment:homomint - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/01 2014/10/16 rogid:XHm0ijYaG0j8tgLPUILBSkUVN6E9606 rogid:YMP60LeA62hg4mNz15o70E/PqwE9606 intact-crc:9B46327AF4101120|rigid:RwHi8bBqOSVaYW+mPwcOgyx0BA4 false tag:?-?(MINT-7556996) glutathione s tranferase tag:?-?(MINT-7556992) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)