#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12118 uniprotkb:Q12285 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650135|imex:IM-19493-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:33539B74F742BD3C crc64:CE6FC4282E0E472C figure legend:Fig. 1A, 1B|comment:Interaction not observed in MDY2-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:D13BCB607D53BE47|rigid:3Q0+iQa7D4oGa7Od3pQXheiXEY4 false necessary binding region:1-58 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12118 uniprotkb:Q12125 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650135|imex:IM-19493-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:33539B74F742BD3C crc64:98AFFDB4EA51B40F figure legend:Fig. 1A, 1B|comment:Interaction not observed in MDY2-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:D13BCB607D53BE47|rigid:3Q0+iQa7D4oGa7Od3pQXheiXEY4 false necessary binding region:1-58 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12285 uniprotkb:Q12125 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650144|imex:IM-19493-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:98AFFDB4EA51B40F figure legend:Fig. 1B, 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:9FB2FB04E7F5CFE2|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false necessary binding region:1-68 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12118 uniprotkb:Q12285 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650151|imex:IM-19493-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:33539B74F742BD3C crc64:CE6FC4282E0E472C figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:27D0CF6A6DD7D767|rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y false - sufficient binding region:69-153 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12125 uniprotkb:Q12154 intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650224|imex:IM-19493-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:98AFFDB4EA51B40F crc64:F795C359B5A4A461 figure legend:Fig. 6B, 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:F8EC43BC9954A719|rigid:vcn4Hx0eoXI4FTBDJOAtVliA7H4 false necessary binding region:1-148 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12154 uniprotkb:Q12285 intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650231|imex:IM-19493-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:F795C359B5A4A461 crc64:CE6FC4282E0E472C figure legend:Fig. 6B|comment:Interaction not observed in YOR164c -/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:CA6AA78FB302F860|rigid:pAtTWkWjsXdxP6ZRGonxYwOZuU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12154 uniprotkb:Q12125 intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650231|imex:IM-19493-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:F795C359B5A4A461 crc64:98AFFDB4EA51B40F figure legend:Fig. 6B|comment:Interaction not observed in YOR164c -/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:CA6AA78FB302F860|rigid:pAtTWkWjsXdxP6ZRGonxYwOZuU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12285 uniprotkb:Q12125 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650244|imex:IM-19493-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:98AFFDB4EA51B40F figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:8FFD57B8397F75DA|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false - necessary binding region:149-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12285 uniprotkb:Q12125 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650167|imex:IM-19493-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:98AFFDB4EA51B40F comment:Sgt2 also appears to be identified on the gel but is not described in the text.|figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:0D339EFAD785C83A|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12285 uniprotkb:Q12125 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650178|imex:IM-19493-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:98AFFDB4EA51B40F figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:56F38FCB51415C9D|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12125 uniprotkb:Q12285 intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0096"(pull down) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650188|imex:IM-19493-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:98AFFDB4EA51B40F crc64:CE6FC4282E0E472C figure legend:Fig. 4C|comment:"Although Q12285 was originally cloned as a full length protein, after 3 months of storage at 4C, two major stable fragments remained. Mass spectrometry and N-terminal sequencing revealed that they were the full-length Get4 and the N-terminal fragment of Get5 (Get5N, residues 2-59)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2010/04/27 2014/10/16 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:E388F9A6551FF63D|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false his tag:?-? sufficient binding region:2-59 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12125 uniprotkb:Q12285 intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2650251|wwpdb:2wpv|imex:IM-19493-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:98AFFDB4EA51B40F crc64:CE6FC4282E0E472C figure legend:Fig. 5|3d-r-factors:1.99A|3d-r-factors:"R-factor: 17.5%, Free R-factor: 20.6%"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/27 2014/10/16 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:B85C0F39F889E7E3|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false his tag:?-? sufficient binding region:2-59 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12285 uniprotkb:Q12154 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650204|imex:IM-19493-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:F795C359B5A4A461 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:A49C37EF504C3544|rigid:pAtTWkWjsXdxP6ZRGonxYwOZuU0 false sufficient binding region:2-59 - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q12285 uniprotkb:Q12125 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650204|imex:IM-19493-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:CE6FC4282E0E472C crc64:98AFFDB4EA51B40F figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/27 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 intact-crc:A49C37EF504C3544|rigid:pAtTWkWjsXdxP6ZRGonxYwOZuU0 false sufficient binding region:2-59 his tag:?-? - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q12125 uniprotkb:Q12285 intact:EBI-36940|uniprotkb:D6W2M2|ensemblfungi:YOR164C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:get4_yeast(display_long)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:O3580(orf name)|uniprotkb:YOR164C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 4(gene name synonym) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0096"(pull down) Chang et al. (2010) pubmed:20106980|imex:IM-19493 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2650270|imex:IM-19493-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005690|refseq:NP_014807.3|mint:Q12125|dip:DIP-2005N|ensemblfungi:YOR164C(gene)|ensemblfungi:YOR164C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:98AFFDB4EA51B40F crc64:CE6FC4282E0E472C figure legend:Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/04/27 2014/10/16 rogid:t1xcIrahizw7d4/IGrx82rIEkOU559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:E2FAD3DD505804F9|rigid:fkMm0OkN22Ito7X24btlNd3+BOU false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)