#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04909	uniprotkb:Q10337	intact:EBI-7764873|ensemblfungi:"SPCC622.08c.1:pep"|intact:MINT-4783472	intact:EBI-7764855|ensemblfungi:"SPBC582.05c.1:pep"|intact:MINT-4698908	psi-mi:h2a1_schpo(display_long)|uniprotkb:hta1(gene name)|psi-mi:hta1(display_short)|uniprotkb:SPCC622.08c(orf name)|uniprotkb:H2A.1(gene name synonym)	psi-mi:brc1_schpo(display_long)|uniprotkb:brc1(gene name)|psi-mi:brc1(display_short)|uniprotkb:SPBC582.05c(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Williams et al. (2010)	pubmed:20094029|imex:IM-15095|mint:MINT-7896851|doi:10.1038/emboj.2009.413	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7764894|mint:MINT-7896859|imex:IM-15095-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P04909|interpro:IPR032454|interpro:IPR032458|ensemblfungi:SPCC622.08c(gene)|ensemblfungi:SPCC622.08c.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140463"(chromatin-protein adaptor)|refseq:NP_588180.1|mint:MINT-7896865(identity)	interpro:IPR001357(BRCT)|mint:Q10337|ensemblfungi:SPBC582.05c(gene)|ensemblfungi:SPBC582.05c.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006301"(postreplication repair)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035861"(site of double-strand break)|go:"GO:0099115"(chromosome, subtelomeric region)|rcsb pdb:3L41|rcsb pdb:3L40|refseq:NP_595173.1|interpro:IPR036420|mint:MINT-7896861(identity)	-	comment:mint|function:"Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"	comment:mint|function:Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization	comment:domino|comment:mint|figure legend:st2 f2c f3a f3b f3d f3e f4a f4d f7a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:sCdrntFH0c0Jd/NtTYNvsD5e4q8284812	rogid:WBn0Q65+QJkLJ9nTUJCFCR5r8+w284812	intact-crc:5082695B03C444B1|rigid:ge3U/zdS1z2pJJK54ffwurC7I5s	false	binding-associated region:127-132(MINT-7896872)|phosphorylated residue:129-129(MINT-7896878)	binding-associated region:659-878(MINT-7896867)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10337	uniprotkb:P04909	intact:EBI-7764855|ensemblfungi:"SPBC582.05c.1:pep"|intact:MINT-4698908	intact:EBI-7764873|ensemblfungi:"SPCC622.08c.1:pep"|intact:MINT-4783472	psi-mi:brc1_schpo(display_long)|uniprotkb:brc1(gene name)|psi-mi:brc1(display_short)|uniprotkb:SPBC582.05c(orf name)	psi-mi:h2a1_schpo(display_long)|uniprotkb:hta1(gene name)|psi-mi:hta1(display_short)|uniprotkb:SPCC622.08c(orf name)|uniprotkb:H2A.1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Williams et al. (2010)	pubmed:20094029|imex:IM-15095|mint:MINT-7896851|doi:10.1038/emboj.2009.413	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7764977|mint:MINT-7896883|imex:IM-15095-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001357(BRCT)|mint:Q10337|ensemblfungi:SPBC582.05c(gene)|ensemblfungi:SPBC582.05c.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006301"(postreplication repair)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035861"(site of double-strand break)|go:"GO:0099115"(chromosome, subtelomeric region)|rcsb pdb:3L41|rcsb pdb:3L40|refseq:NP_595173.1|interpro:IPR036420|mint:MINT-7896885(identity)	interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P04909|interpro:IPR032454|interpro:IPR032458|ensemblfungi:SPCC622.08c(gene)|ensemblfungi:SPCC622.08c.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140463"(chromatin-protein adaptor)|refseq:NP_588180.1|mint:MINT-7896890(identity)	-	comment:mint|function:Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization	comment:mint|function:"Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"	figure legend:f2a|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:WBn0Q65+QJkLJ9nTUJCFCR5r8+w284812	rogid:sCdrntFH0c0Jd/NtTYNvsD5e4q8284812	intact-crc:A349F99A8DBF4836|rigid:ge3U/zdS1z2pJJK54ffwurC7I5s	false	binding-associated region:659-878(MINT-7896886)|mutation disrupting interaction:672-672(MINT-7896904)	phosphorylated residue:129-129(MINT-7896891)|tag:?-?(MINT-7896901)|binding-associated region:124-132(MINT-7896893)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:Q10337	uniprotkb:P04909	intact:EBI-7764855|ensemblfungi:"SPBC582.05c.1:pep"|intact:MINT-4698908	intact:EBI-7764873|ensemblfungi:"SPCC622.08c.1:pep"|intact:MINT-4783472	psi-mi:brc1_schpo(display_long)|uniprotkb:brc1(gene name)|psi-mi:brc1(display_short)|uniprotkb:SPBC582.05c(orf name)	psi-mi:h2a1_schpo(display_long)|uniprotkb:hta1(gene name)|psi-mi:hta1(display_short)|uniprotkb:SPCC622.08c(orf name)|uniprotkb:H2A.1(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Williams et al. (2010)	pubmed:20094029|imex:IM-15095|mint:MINT-7896851|doi:10.1038/emboj.2009.413	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7765033|mint:MINT-7896907|imex:IM-15095-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001357(BRCT)|mint:Q10337|ensemblfungi:SPBC582.05c(gene)|ensemblfungi:SPBC582.05c.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006301"(postreplication repair)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035861"(site of double-strand break)|go:"GO:0099115"(chromosome, subtelomeric region)|rcsb pdb:3L41|rcsb pdb:3L40|refseq:NP_595173.1|interpro:IPR036420|mint:MINT-7896909(identity)	interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P04909|interpro:IPR032454|interpro:IPR032458|ensemblfungi:SPCC622.08c(gene)|ensemblfungi:SPCC622.08c.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140463"(chromatin-protein adaptor)|refseq:NP_588180.1|mint:MINT-7896916(identity)	-	comment:mint|function:Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization	comment:mint|function:"Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"	figure legend:f2b|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:WBn0Q65+QJkLJ9nTUJCFCR5r8+w284812	rogid:sCdrntFH0c0Jd/NtTYNvsD5e4q8284812	intact-crc:2A7BCA88348F6ABC|rigid:ge3U/zdS1z2pJJK54ffwurC7I5s	false	mutation disrupting interaction:672-672(MINT-7896910)|binding-associated region:659-878(MINT-7896912)	binding-associated region:124-132(MINT-7896919)|phosphorylated residue:129-129(MINT-7896921)|tag:?-?(MINT-7896917)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:Q10337	uniprotkb:P04909	intact:EBI-7764855|ensemblfungi:"SPBC582.05c.1:pep"|intact:MINT-4698908	intact:EBI-7764873|ensemblfungi:"SPCC622.08c.1:pep"|intact:MINT-4783472	psi-mi:brc1_schpo(display_long)|uniprotkb:brc1(gene name)|psi-mi:brc1(display_short)|uniprotkb:SPBC582.05c(orf name)	psi-mi:h2a1_schpo(display_long)|uniprotkb:hta1(gene name)|psi-mi:hta1(display_short)|uniprotkb:SPCC622.08c(orf name)|uniprotkb:H2A.1(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Williams et al. (2010)	pubmed:20094029|imex:IM-15095|mint:MINT-7896851|doi:10.1038/emboj.2009.413	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7765090|mint:MINT-7896929|imex:IM-15095-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001357(BRCT)|mint:Q10337|ensemblfungi:SPBC582.05c(gene)|ensemblfungi:SPBC582.05c.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006301"(postreplication repair)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035861"(site of double-strand break)|go:"GO:0099115"(chromosome, subtelomeric region)|rcsb pdb:3L41|rcsb pdb:3L40|refseq:NP_595173.1|interpro:IPR036420|mint:MINT-7896931(identity)	interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P04909|interpro:IPR032454|interpro:IPR032458|ensemblfungi:SPCC622.08c(gene)|ensemblfungi:SPCC622.08c.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140463"(chromatin-protein adaptor)|refseq:NP_588180.1|mint:MINT-7896938(identity)	-	comment:mint|function:Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization	comment:mint|function:"Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"	figure legend:f2d|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/05/27	2014/10/16	rogid:WBn0Q65+QJkLJ9nTUJCFCR5r8+w284812	rogid:sCdrntFH0c0Jd/NtTYNvsD5e4q8284812	intact-crc:059C0D3A78D1A0CE|rigid:ge3U/zdS1z2pJJK54ffwurC7I5s	false	binding-associated region:659-878(MINT-7896932)	binding-associated region:124-132(MINT-7896941)|phosphorylated residue:129-129(MINT-7896939)|tag:?-?(MINT-7896943)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)