#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7Z434	uniprotkb:Q8IWA4	intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969|ensembl:ENSP00000420617|uniprotkb:A0A0C4DFN1	psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Castanier et al. (2010)	pubmed:20019757|imex:IM-15452|mint:MINT-7713196|doi:10.1038/embor.2009.258	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7692229|mint:MINT-7713992|imex:IM-15452-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N|mint:MINT-7713994(identity)	refseq:NP_284941.2|ensembl:ENSG00000171109(gene)|ensembl:ENST00000263969(transcript)|ensembl:ENST00000471841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|interpro:IPR027088|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0098799"(outer mitochondrial membrane protein complex)|go:"GO:1990613"(mitochondrial membrane fusion)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|refseq:XP_005247653.2|dip:DIP-50289N|mint:MINT-7713995(identity)	-	-	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/03/17	2018/04/06	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	intact-crc:26127866EAD1865F|rigid:/S0bGDZYFkVHOH9ScToDDZfs814	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z434	uniprotkb:Q8IWA4	intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969|ensembl:ENSP00000420617|uniprotkb:A0A0C4DFN1	psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Castanier et al. (2010)	pubmed:20019757|imex:IM-15452|mint:MINT-7713196|doi:10.1038/embor.2009.258	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7692241|mint:MINT-7714001|imex:IM-15452-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N|mint:MINT-7714005(identity)	refseq:NP_284941.2|ensembl:ENSG00000171109(gene)|ensembl:ENST00000263969(transcript)|ensembl:ENST00000471841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|interpro:IPR027088|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0098799"(outer mitochondrial membrane protein complex)|go:"GO:1990613"(mitochondrial membrane fusion)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|refseq:XP_005247653.2|dip:DIP-50289N|mint:MINT-7714003(identity)	-	-	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/03/17	2018/04/06	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	intact-crc:26389CA15CA9AEC1|rigid:/S0bGDZYFkVHOH9ScToDDZfs814	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)