#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52286 uniprotkb:Q12018 intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634405|mint:MINT-7555509|imex:IM-15561-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555518(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555511(identity) - crc64:746DDE6470A69432 crc64:22BC8B35034EDDEF comment:homomint|comment:mint|figure legend:fs2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:A31049E84AEA7DAE|rigid:jOTJGUJ8/FiR/WQblFXHrdihz0k false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12018 uniprotkb:Q92325 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634447|mint:MINT-7555540|imex:IM-15561-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555542(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555543(identity) - crc64:22BC8B35034EDDEF - figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:9C260085E2D3CA18|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false - mutation decreasing interaction:551-551(MINT-7555549)|mutation decreasing interaction:552-552(MINT-7555552) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:Q12018 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634435|mint:MINT-7555527|imex:IM-15561-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555530(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555529(identity) - - crc64:22BC8B35034EDDEF comment:mint|figure legend:f1c f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:A10BF9B952421A99|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:Q12018 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634493|mint:MINT-7555763|imex:IM-15561-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555765(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555766(identity) - - crc64:22BC8B35034EDDEF figure legend:f5c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:37353803235EA001|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12018 uniprotkb:Q92325 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634466|mint:MINT-7555561|imex:IM-15561-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555569(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555563(identity) - crc64:22BC8B35034EDDEF - figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:8FF4403B6F95B948|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false - mutation disrupting interaction:23-23(MINT-7555576)|mutation disrupting interaction:19-19(MINT-7555566)|mutation disrupting interaction:17-17(MINT-7555564)|mutation disrupting interaction:22-22(MINT-7555573) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:Q12018 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0018"(two hybrid) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7634513|mint:MINT-7555476|imex:IM-15561-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555478(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555479(identity) - - crc64:22BC8B35034EDDEF comment:mint|figure legend:fs2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:2B472FB5F138144A|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12018 uniprotkb:Q92325 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0071"(molecular sieving) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634551|mint:MINT-7555662|imex:IM-15561-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555664(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555665(identity) - crc64:22BC8B35034EDDEF - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:7016E8ACC5DB7BAF|rigid:URyOtYCJkbBZIjaDuVNYHorcnQE false his tag:?-?(MINT-7555671) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12018 uniprotkb:Q08273 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name) psi-mi:"MI:0071"(molecular sieving) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634551|mint:MINT-7555662|imex:IM-15561-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555664(identity) refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555666(identity) - crc64:22BC8B35034EDDEF crc64:A9C3193E48CAF881 figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292 intact-crc:7016E8ACC5DB7BAF|rigid:URyOtYCJkbBZIjaDuVNYHorcnQE false his tag:?-?(MINT-7555671) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12018 uniprotkb:Q12395 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-29871|uniprotkb:D6VYC3|ensemblfungi:YLR128W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:dcn1_yeast(display_long)|uniprotkb:L3111(orf name)|uniprotkb:YLR128W(locus name)|uniprotkb:DCN1(gene name)|psi-mi:DCN1(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634578|mint:MINT-7555775|imex:IM-15561-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555778(identity) refseq:NP_013229.1|sgd:S000004118|dip:DIP-1238N|mint:Q12395|ensemblfungi:YLR128W(gene)|ensemblfungi:YLR128W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR009060(UBA-like)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|rcsb pdb:2IS9|rcsb pdb:2L4E|rcsb pdb:2L4F|rcsb pdb:3BQ3|rcsb pdb:3O2P|rcsb pdb:3O6B|rcsb pdb:3TDI|reactome:R-SCE-8951664|mint:MINT-7555777(identity) - crc64:22BC8B35034EDDEF - comment:homomint|comment:mint|figure legend:fs5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:y1U1q7ehVNnMasWO+LOimtMaoCY559292 intact-crc:F8F6A185FD7990DF|rigid:/CaMkPL8W63kqzC5Us9xaPFPx30 false - binding-associated region:70-269(MINT-7555787) - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12018 uniprotkb:Q92325 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634578|mint:MINT-7555775|imex:IM-15561-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555778(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555779(identity) - crc64:22BC8B35034EDDEF - comment:homomint|comment:mint|figure legend:fs5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/20 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:F8F6A185FD7990DF|rigid:/CaMkPL8W63kqzC5Us9xaPFPx30 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q03919 uniprotkb:Q92325 intact:EBI-37695|uniprotkb:D6VSC2|ensemblfungi:YDR139C intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:rub1_yeast(display_long)|uniprotkb:RUB1(gene name)|psi-mi:RUB1(display_short)|uniprotkb:YDR139C(locus name)|uniprotkb:Ubiquitin-like protein RUB1(gene name synonym)|uniprotkb:YD9302.15C(orf name)|uniprotkb:Related to ubiquitin protein 1(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634605|mint:MINT-7555731|imex:IM-15561-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002546|refseq:NP_010423.4|dip:DIP-1627N|mint:Q03919|ensemblfungi:YDR139C(gene)|ensemblfungi:YDR139C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-SCE-5689603|reactome:R-SCE-8856825|reactome:R-SCE-8951664|mint:MINT-7555733(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7555735(identity) - crc64:F05DBF3C8E464FD1 - figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:mkNmJcrULs8tRZ4xqik0XE8V3fs559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:6A99F83A90CC1CA4|rigid:L9mITYimOM7Rf5atk4MuYi+1EMI false ha tag:?-?(MINT-7555737) neddylated lysine:?-?(MINT-7555744) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03919 uniprotkb:Q12018 intact:EBI-37695|uniprotkb:D6VSC2|ensemblfungi:YDR139C intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:rub1_yeast(display_long)|uniprotkb:RUB1(gene name)|psi-mi:RUB1(display_short)|uniprotkb:YDR139C(locus name)|uniprotkb:Ubiquitin-like protein RUB1(gene name synonym)|uniprotkb:YD9302.15C(orf name)|uniprotkb:Related to ubiquitin protein 1(gene name synonym) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Siergiejuk et al. (2009) pubmed:19942853|imex:IM-15561|mint:MINT-7555458|doi:10.1038/emboj.2009.354 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7634605|mint:MINT-7555731|imex:IM-15561-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002546|refseq:NP_010423.4|dip:DIP-1627N|mint:Q03919|ensemblfungi:YDR139C(gene)|ensemblfungi:YDR139C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-SCE-5689603|reactome:R-SCE-8856825|reactome:R-SCE-8951664|mint:MINT-7555733(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7555734(identity) - crc64:F05DBF3C8E464FD1 crc64:22BC8B35034EDDEF figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/20 2014/10/16 rogid:mkNmJcrULs8tRZ4xqik0XE8V3fs559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:6A99F83A90CC1CA4|rigid:L9mITYimOM7Rf5atk4MuYi+1EMI false ha tag:?-?(MINT-7555737) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)