#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60285	uniprotkb:O95835	intact:EBI-1046789|uniprotkb:A7MD39|uniprotkb:Q96KA8|ensembl:ENSP00000261402|intact:EBI-28968258	intact:EBI-444209|uniprotkb:Q6PKD0|ensembl:ENSP00000253339|ensembl:ENSP00000437550	psi-mi:nuak1_human(display_long)|uniprotkb:AMPK-related protein kinase 5(gene name synonym)|uniprotkb:NUAK1(gene name)|psi-mi:NUAK1(display_short)|uniprotkb:ARK5(gene name synonym)|uniprotkb:KIAA0537(gene name synonym)|uniprotkb:OMPHK1(gene name synonym)|uniprotkb:Omphalocele kinase 1(gene name synonym)	psi-mi:lats1_human(display_long)|uniprotkb:Large tumor suppressor homolog 1(gene name synonym)|uniprotkb:WARTS protein kinase(gene name synonym)|uniprotkb:LATS1(gene name)|psi-mi:LATS1(display_short)|uniprotkb:WARTS(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Humbert et al. (2010)	pubmed:19927127|imex:IM-15099|mint:MINT-7717767|doi:10.1038/emboj.2009.342	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7610933|mint:MINT-7717777|imex:IM-15099-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055655.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-6804756|go:"GO:2000772"(regulation of cellular senescence)|ensembl:ENSG00000074590(gene)|ensembl:ENST00000261402(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENSP00000261402|mint:MINT-7717779(identity)	refseq:NP_004681.1|ensembl:ENSP00000253339|ensembl:ENST00000392273|ensembl:ENSP00000444678|ensembl:ENSP00000437550|refseq:NP_001257448.1|dip:DIP-31516N|ensembl:ENSG00000131023(gene)|ensembl:ENST00000253339(transcript)|ensembl:ENST00000543571(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0000922"(spindle pole)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0001828"(inner cell mass cellular morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030496"(midbody)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009060(UBA-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028741|interpro:IPR042706|rcsb pdb:4ZRK|rcsb pdb:5B5W|rcsb pdb:5BRK|reactome:R-HSA-2028269|mint:MINT-7717780(identity)	-	-	-	figure legend:f7a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2010/03/29	2014/10/16	rogid:6P4GR2fFthBsniiqq/yy3Sxm9Sg9606	rogid:9HqrE1bBG99E3O2d2ezyRtg2Bd49606	intact-crc:56B8AC2395C350A2|rigid:pK7a/X6PijieIiXV2cMR6iYD0BQ	false	flag tag:?-?(MINT-7717786)	myc tag:?-?(MINT-7717782)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60285	uniprotkb:O95835	intact:EBI-1046789|uniprotkb:A7MD39|uniprotkb:Q96KA8|ensembl:ENSP00000261402|intact:EBI-28968258	intact:EBI-444209|uniprotkb:Q6PKD0|ensembl:ENSP00000253339|ensembl:ENSP00000437550	psi-mi:nuak1_human(display_long)|uniprotkb:AMPK-related protein kinase 5(gene name synonym)|uniprotkb:NUAK1(gene name)|psi-mi:NUAK1(display_short)|uniprotkb:ARK5(gene name synonym)|uniprotkb:KIAA0537(gene name synonym)|uniprotkb:OMPHK1(gene name synonym)|uniprotkb:Omphalocele kinase 1(gene name synonym)	psi-mi:lats1_human(display_long)|uniprotkb:Large tumor suppressor homolog 1(gene name synonym)|uniprotkb:WARTS protein kinase(gene name synonym)|uniprotkb:LATS1(gene name)|psi-mi:LATS1(display_short)|uniprotkb:WARTS(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Humbert et al. (2010)	pubmed:19927127|imex:IM-15099|mint:MINT-7717767|doi:10.1038/emboj.2009.342	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7610978|mint:MINT-7717790|imex:IM-15099-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055655.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-6804756|go:"GO:2000772"(regulation of cellular senescence)|ensembl:ENSG00000074590(gene)|ensembl:ENST00000261402(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENSP00000261402|mint:MINT-7717796(identity)	refseq:NP_004681.1|ensembl:ENSP00000253339|ensembl:ENST00000392273|ensembl:ENSP00000444678|ensembl:ENSP00000437550|refseq:NP_001257448.1|dip:DIP-31516N|ensembl:ENSG00000131023(gene)|ensembl:ENST00000253339(transcript)|ensembl:ENST00000543571(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0000922"(spindle pole)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0001828"(inner cell mass cellular morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030496"(midbody)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009060(UBA-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028741|interpro:IPR042706|rcsb pdb:4ZRK|rcsb pdb:5B5W|rcsb pdb:5BRK|reactome:R-HSA-2028269|mint:MINT-7717792(identity)	-	-	-	figure legend:f7b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-wi_38)|taxid:9606(Homo sapiens Caucasian fetal lung fibroblast cell line)	-	2010/03/29	2014/10/16	rogid:6P4GR2fFthBsniiqq/yy3Sxm9Sg9606	rogid:9HqrE1bBG99E3O2d2ezyRtg2Bd49606	intact-crc:78B23DC92EDCD59E|rigid:pK7a/X6PijieIiXV2cMR6iYD0BQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)