#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53866 uniprotkb:P53131 intact:EBI-29168|uniprotkb:D6W0W6|ensemblfungi:YNL224C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:sqs1_yeast(display_long)|uniprotkb:Squelch of splicing suppression protein 1(gene name synonym)|uniprotkb:YNL224C(locus name)|uniprotkb:N1269(orf name)|uniprotkb:SQS1(gene name)|psi-mi:SQS1(display_short) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0096"(pull down) Lebaron et al. (2009) pubmed:19927118|imex:IM-13900|mint:MINT-7556115|doi:10.1038/emboj.2009.335 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7605118|mint:MINT-7556123|imex:IM-13900-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014175.1|sgd:S000005168|dip:DIP-6728N|mint:P53866|ensemblfungi:YNL224C(gene)|ensemblfungi:YNL224C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000467(D111/G-patch)|interpro:IPR034082|interpro:IPR036867|mint:MINT-7556127(identity) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131|mint:MINT-7556125(identity) - - crc64:DA8A085EC50FF430 figure legend:f1b f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/26 2014/10/16 rogid:1SI9Z4+ileBAQJdISG0uhYtjy4c559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:F4CE5DFD22FB583A|rigid:YccIs1EqaSuCfIjPqHJQv8aJqP0 false his tag:?-?(MINT-7556135) his tag:?-?(MINT-7556131)|binding-associated region:1-202(MINT-7556139) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P53866 uniprotkb:P53131 intact:EBI-29168|uniprotkb:D6W0W6|ensemblfungi:YNL224C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:sqs1_yeast(display_long)|uniprotkb:Squelch of splicing suppression protein 1(gene name synonym)|uniprotkb:YNL224C(locus name)|uniprotkb:N1269(orf name)|uniprotkb:SQS1(gene name)|psi-mi:SQS1(display_short) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0096"(pull down) Lebaron et al. (2009) pubmed:19927118|imex:IM-13900|mint:MINT-7556115|doi:10.1038/emboj.2009.335 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7605156|mint:MINT-7556142|imex:IM-13900-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014175.1|sgd:S000005168|dip:DIP-6728N|mint:P53866|ensemblfungi:YNL224C(gene)|ensemblfungi:YNL224C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000467(D111/G-patch)|interpro:IPR034082|interpro:IPR036867|mint:MINT-7556144(identity) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131|mint:MINT-7556148(identity) - - crc64:DA8A085EC50FF430 figure legend:f1b f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/26 2014/10/16 rogid:1SI9Z4+ileBAQJdISG0uhYtjy4c559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:B1082B5B71D3CE49|rigid:YccIs1EqaSuCfIjPqHJQv8aJqP0 false his tag:?-?(MINT-7556145) his tag:?-?(MINT-7556151)|binding-associated region:574-767(MINT-7556149) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53866 uniprotkb:P53131 intact:EBI-29168|uniprotkb:D6W0W6|ensemblfungi:YNL224C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:sqs1_yeast(display_long)|uniprotkb:Squelch of splicing suppression protein 1(gene name synonym)|uniprotkb:YNL224C(locus name)|uniprotkb:N1269(orf name)|uniprotkb:SQS1(gene name)|psi-mi:SQS1(display_short) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0676"(tandem affinity purification) Lebaron et al. (2009) pubmed:19927118|imex:IM-13900|mint:MINT-7556115|doi:10.1038/emboj.2009.335 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7605185|mint:MINT-7556205|imex:IM-13900-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014175.1|sgd:S000005168|dip:DIP-6728N|mint:P53866|ensemblfungi:YNL224C(gene)|ensemblfungi:YNL224C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000467(D111/G-patch)|interpro:IPR034082|interpro:IPR036867|mint:MINT-7556207(identity) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131|mint:MINT-7556208(identity) - - crc64:DA8A085EC50FF430 figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/01/26 2014/10/16 rogid:1SI9Z4+ileBAQJdISG0uhYtjy4c559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:9A02B04E4F315A7E|rigid:YccIs1EqaSuCfIjPqHJQv8aJqP0 false calmodulin binding peptide plus protein a tag:?-?(MINT-7556216) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)