#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q71U36	uniprotkb:Q9NQC7	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572503|mint:MINT-7561617|imex:IM-15538-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7561620(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7561619(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanocyte)|taxid:9606(Homo sapiens melanocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:E2B5A904D4F0E90B|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q71U36	uniprotkb:Q9NQC7	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572533|mint:MINT-7561703|imex:IM-15538-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7561705(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7561707(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f1b, f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanocyte)|taxid:9606(Homo sapiens melanocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:CE7D4A69DF16055C|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P68369	uniprotkb:Q80TQ2	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572707|mint:MINT-7562957|imex:IM-15538-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7562959(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7562960(identity)	-	-	-	figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:DC72F7065BBE4DF5|rigid:wCXGir76pu/07ROwdlK1E2qYw6U	false	monoacetylated residue:?-?(MINT-7562985)	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P68369	uniprotkb:P27546	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572633|mint:MINT-7561872|imex:IM-15538-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7561874(identity)	refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1|mint:MINT-7561947(identity)	-	-	-	figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	rogid:DVblnhNfUaxX6rpvxn660Pq09L410090	intact-crc:2E83140B0F03BA4B|rigid:XIJIwNax/ULXfvmnVjNMBL8GJVk	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P68369	uniprotkb:Q80TQ2	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572633|mint:MINT-7561872|imex:IM-15538-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7561874(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7561875(identity)	-	-	-	figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:2E83140B0F03BA4B|rigid:XIJIwNax/ULXfvmnVjNMBL8GJVk	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9Z2F6	uniprotkb:Q80TQ2	intact:EBI-943884|ensembl:ENSMUSP00000113851	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:bcl3_mouse(display_long)|uniprotkb:Bcl3(gene name)|psi-mi:Bcl3(display_short)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572722|mint:MINT-7563396|imex:IM-15538-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291079.2|ensembl:ENSMUSG00000053175(gene)|ensembl:ENSMUST00000120537(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:MINT-7563399(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7563398(identity)	-	-	-	figure legend:f3g|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:9YpC2b1vDMZI3K2+ah6RlSsB04I10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:EBD7A4CF1A3D9702|rigid:vpMeqvKHeMnT8ZXJVYiQ2U5PRes	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9Z2V5	uniprotkb:P68369	intact:EBI-1009256|uniprotkb:B1AUA6|ensembl:ENSMUSP00000033501|ensembl:ENSMUSP00000111306	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	psi-mi:hdac6_mouse(display_long)|uniprotkb:Histone deacetylase mHDA2(gene name synonym)|uniprotkb:Hdac6(gene name)|psi-mi:Hdac6(display_short)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572747|mint:MINT-7610403|imex:IM-15538-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123888.1|refseq:NP_034543.3|ensembl:ENSMUSG00000031161(gene)|ensembl:ENSMUST00000033501(transcript)|ensembl:ENSMUST00000115642(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005901"(caveola)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0030424"(axon)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3371511|reactome:R-MMU-350054|reactome:R-MMU-5617833|reactome:R-MMU-9646399|refseq:XP_006527630.1|refseq:XP_017173877.1|refseq:XP_017173878.1|dip:DIP-36461N|mint:MINT-7610405(identity)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7610406(identity)	-	-	-	figure legend:f5d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:nvUUsssLQM03b2wLNbk7eb/5SxM10090	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	intact-crc:DD4CC09CF74AFFB3|rigid:rbSZC6u/eCf/B0UinEnkGHgojtA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q80TQ2	uniprotkb:Q9Z2V5	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	intact:EBI-1009256|uniprotkb:B1AUA6|ensembl:ENSMUSP00000033501|ensembl:ENSMUSP00000111306	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:hdac6_mouse(display_long)|uniprotkb:Histone deacetylase mHDA2(gene name synonym)|uniprotkb:Hdac6(gene name)|psi-mi:Hdac6(display_short)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572735|mint:MINT-7564067|imex:IM-15538-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7564069(identity)	refseq:NP_001123888.1|refseq:NP_034543.3|ensembl:ENSMUSG00000031161(gene)|ensembl:ENSMUST00000033501(transcript)|ensembl:ENSMUST00000115642(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005901"(caveola)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0030424"(axon)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3371511|reactome:R-MMU-350054|reactome:R-MMU-5617833|reactome:R-MMU-9646399|refseq:XP_006527630.1|refseq:XP_017173877.1|refseq:XP_017173878.1|dip:DIP-36461N|mint:MINT-7564070(identity)	-	-	-	figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	rogid:nvUUsssLQM03b2wLNbk7eb/5SxM10090	intact-crc:46AE0EF10B112F03|rigid:8chaBt6BUi6V0le1bBnvx0NSf24	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P68369	uniprotkb:Q80TQ2	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572758|mint:MINT-7679670|imex:IM-15538-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7679676(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7679674(identity)	-	-	-	comment:mint|figure legend:fs3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:B5F5A19D2A9657D0|rigid:wCXGir76pu/07ROwdlK1E2qYw6U	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9NQC7	uniprotkb:Q71U36	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572795|mint:MINT-7562676|imex:IM-15538-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7562678(identity)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7562679(identity)	-	-	-	figure legend:f1f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/02/08	2014/10/16	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	intact-crc:BA3006EF20B07257|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	flag tag:?-?(MINT-7562732)|binding-associated region:1-318(MINT-7562735)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q9NQC7	uniprotkb:Q9UBN7	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572848|mint:MINT-7565823|imex:IM-15538-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7565825(identity)	go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N|mint:MINT-7565826(identity)	-	-	-	figure legend:f4e|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/02/08	2014/10/16	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606	intact-crc:BFCCEBE003469452|rigid:H5xjFpdSRnWwVPa5MA2drjFOUMQ	false	flag tag:?-?(MINT-7566126)	ha tag:?-?(MINT-7695811)|binding-associated region:?-?(MINT-7566096)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NQC7	uniprotkb:Q9UBN7	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572830|mint:MINT-7564471|imex:IM-15538-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7564473(identity)	go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N|mint:MINT-7564474(identity)	-	-	-	figure legend:f4d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/02/08	2014/10/16	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606	intact-crc:2A25306D861806F9|rigid:H5xjFpdSRnWwVPa5MA2drjFOUMQ	false	flag tag:?-?(MINT-7564490)|binding-associated region:1-212(MINT-7564493)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q80TQ2	uniprotkb:Q9Z2V5	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	intact:EBI-1009256|uniprotkb:B1AUA6|ensembl:ENSMUSP00000033501|ensembl:ENSMUSP00000111306	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:hdac6_mouse(display_long)|uniprotkb:Histone deacetylase mHDA2(gene name synonym)|uniprotkb:Hdac6(gene name)|psi-mi:Hdac6(display_short)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572933|mint:MINT-7564396|imex:IM-15538-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7564398(identity)	refseq:NP_001123888.1|refseq:NP_034543.3|ensembl:ENSMUSG00000031161(gene)|ensembl:ENSMUST00000033501(transcript)|ensembl:ENSMUST00000115642(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005901"(caveola)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0030424"(axon)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3371511|reactome:R-MMU-350054|reactome:R-MMU-5617833|reactome:R-MMU-9646399|refseq:XP_006527630.1|refseq:XP_017173877.1|refseq:XP_017173878.1|dip:DIP-36461N|mint:MINT-7564399(identity)	-	-	-	figure legend:f4c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	rogid:nvUUsssLQM03b2wLNbk7eb/5SxM10090	intact-crc:23AA38CB814AD45D|rigid:8chaBt6BUi6V0le1bBnvx0NSf24	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q80TQ2	uniprotkb:P68369	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572918|mint:MINT-7562880|imex:IM-15538-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7562883(identity)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7562882(identity)	-	-	-	comment:mint|figure legend:f1a; f3f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	intact-crc:3BBF9050AF762982|rigid:wCXGir76pu/07ROwdlK1E2qYw6U	false	-	monoacetylated residue:?-?(MINT-7679237)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P68369	uniprotkb:Q80TQ2	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572975|mint:MINT-7679329|imex:IM-15538-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295|mint:MINT-7679333(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7679331(identity)	-	-	-	comment:mint|figure legend:fs1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:F33D814FE313CE02|rigid:wCXGir76pu/07ROwdlK1E2qYw6U	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9Z2V5	uniprotkb:Q80TQ2	intact:EBI-1009256|uniprotkb:B1AUA6|ensembl:ENSMUSP00000033501|ensembl:ENSMUSP00000111306	intact:EBI-943859|uniprotkb:Q80VB3|uniprotkb:Q8BXZ3|uniprotkb:Q8BYL9|uniprotkb:Q8CGB0|ensembl:ENSMUSP00000105254|ensembl:ENSMUSP00000147426|ensembl:ENSMUSP00000148037	psi-mi:hdac6_mouse(display_long)|uniprotkb:Histone deacetylase mHDA2(gene name synonym)|uniprotkb:Hdac6(gene name)|psi-mi:Hdac6(display_short)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:cyld_mouse(display_long)|uniprotkb:Cyld(gene name)|psi-mi:Cyld(display_short)|uniprotkb:Cyld1(gene name synonym)|uniprotkb:Kiaa0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7572962|mint:MINT-7611005|imex:IM-15538-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123888.1|refseq:NP_034543.3|ensembl:ENSMUSG00000031161(gene)|ensembl:ENSMUST00000033501(transcript)|ensembl:ENSMUST00000115642(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005901"(caveola)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0030424"(axon)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3371511|reactome:R-MMU-350054|reactome:R-MMU-5617833|reactome:R-MMU-9646399|refseq:XP_006527630.1|refseq:XP_017173877.1|refseq:XP_017173878.1|dip:DIP-36461N|mint:MINT-7611008(identity)	refseq:NP_001121642.1|refseq:NP_001121643.1|refseq:NP_775545.1|refseq:XP_006531477.1|refseq:XP_006531478.1|refseq:XP_006531479.1|refseq:XP_006531480.1|refseq:XP_006531481.1|refseq:XP_011246825.1|refseq:XP_011246826.1|refseq:XP_011246827.1|refseq:XP_017168478.1|dip:DIP-35656N|ensembl:ENSMUSG00000036712(gene)|ensembl:ENSMUST00000109626(transcript)|ensembl:ENSMUST00000209559(transcript)|ensembl:ENSMUST00000211554(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689880|reactome:R-MMU-936440|mint:MINT-7611009(identity)	go:"GO:0030496"(midbody)	-	-	figure legend:f7a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-keratinocyte)|taxid:10090(Mouse Keratinocyte)	-	2010/02/08	2014/10/16	rogid:nvUUsssLQM03b2wLNbk7eb/5SxM10090	rogid:U1ditS+hdqob77g9p8v9kSyOKsE10090	intact-crc:1762771B814AD45F|rigid:8chaBt6BUi6V0le1bBnvx0NSf24	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q71U36	uniprotkb:Q9NQC7	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573030|mint:MINT-7563186|imex:IM-15538-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7563188(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7563189(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2f; fs1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-juso)|taxid:9606(Homo sapiens)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:16B99ED9C58A603E|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	-	green fluorescent protein tag:?-?(MINT-7563274)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQC7	uniprotkb:Q71U36	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573045|mint:MINT-7623764|imex:IM-15538-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7623770(identity)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7623767(identity)	go:"GO:0030496"(midbody)	-	-	comment:homomint|comment:mint|figure legend:f7d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-juso)|taxid:9606(Homo sapiens)	-	2010/02/08	2014/10/16	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	intact-crc:8F79B7031E4CF78D|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	flag tag:?-?(MINT-7623773)|binding-associated region:1-212(MINT-7623771)	monoacetylated residue:?-?(MINT-7623768)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q71U36	uniprotkb:Q9NQC7	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573114|mint:MINT-7679557|imex:IM-15538-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7679559(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7679560(identity)	-	-	-	comment:homomint|comment:mint|figure legend:fs1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanocyte)|taxid:9606(Homo sapiens melanocyte)	-	2010/02/08	2014/10/16	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:EBA3D0FDFB40493D|rigid:azoO+QMBSfFC4hSf+vB92Gvq6AE	false	monoacetylated residue:?-?(MINT-7679626)	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9UBN7	uniprotkb:Q9NQC7	intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573157|mint:MINT-7679902|imex:IM-15538-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N|mint:MINT-7679906(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7679905(identity)	-	-	-	comment:homomint|comment:mint|figure legend:fs5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-juso)|taxid:9606(Homo sapiens)	-	2010/02/08	2014/10/16	rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:FD1F773B4F5BDF06|rigid:UqYA6hasFtZ5pIt5CkcuiNdnO+0	false	-	green fluorescent protein tag:?-?(MINT-7680009)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UBN7	uniprotkb:Q71U36	intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573157|mint:MINT-7679902|imex:IM-15538-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N|mint:MINT-7679906(identity)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|mint:MINT-7679904(identity)	-	-	-	comment:homomint|comment:mint|figure legend:fs5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-juso)|taxid:9606(Homo sapiens)	-	2010/02/08	2014/10/16	rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	intact-crc:FD1F773B4F5BDF06|rigid:UqYA6hasFtZ5pIt5CkcuiNdnO+0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q9UBN7	uniprotkb:Q9NQC7	intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wickström et al. (2010)	pubmed:19893491|imex:IM-15538|mint:MINT-7559471|doi:10.1038/emboj.2009.317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7573192|mint:MINT-7680083|imex:IM-15538-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N|mint:MINT-7680085(identity)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1|mint:MINT-7680087(identity)	-	-	-	comment:homomint|comment:mint|figure legend:sf4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-juso)|taxid:9606(Homo sapiens)	-	2010/02/08	2014/10/16	rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	intact-crc:B86D9E74FB9721C0|rigid:H5xjFpdSRnWwVPa5MA2drjFOUMQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)