#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q00977 uniprotkb:Q8CBC4 intact:EBI-2615361|ensembl:ENSMUSP00000054343 intact:EBI-2615382|uniprotkb:Q8BFS5|uniprotkb:Q8K053|ensembl:ENSMUSP00000048205 psi-mi:cxb2_mouse(display_long)|uniprotkb:Gjb2(gene name)|psi-mi:Gjb2(display_short)|uniprotkb:Cxn-26(gene name synonym)|uniprotkb:Connexin-26(gene name synonym) psi-mi:cnst_mouse(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0018"(two hybrid) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2615411|imex:IM-19064-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032151.1|ensembl:ENSMUST00000055698(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|ensembl:ENSMUSG00000046352(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190872 refseq:NP_666217.2|ensembl:ENSMUSG00000038949(gene)|ensembl:ENSMUST00000040706(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318 - - - figure legend:Fig. 1. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/15 2014/10/16 rogid:avaPYwYewnqkZhtjfJmYRNpKjtw10090 rogid:FykY9TEMok4jY9VhfByb+/zCZYk10090 intact-crc:4065328162A0A6F8|rigid:m81ikSu3mSuwuLzjAvocyQlE8iU false - necessary binding region:521-711 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P70689 uniprotkb:Q8CBC4 intact:EBI-2615416|ensembl:ENSMUSP00000035630 intact:EBI-2615382|uniprotkb:Q8BFS5|uniprotkb:Q8K053|ensembl:ENSMUSP00000048205 psi-mi:cxb6_mouse(display_long)|uniprotkb:Gjb6(gene name)|psi-mi:Gjb6(display_short)|uniprotkb:Cxn-30(gene name synonym)|uniprotkb:Connexin-30(gene name synonym) psi-mi:cnst_mouse(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0018"(two hybrid) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2615437|imex:IM-19064-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258592.1|refseq:NP_001010937.1|refseq:XP_006518623.1|refseq:XP_006518624.1|ensembl:ENSMUST00000039380(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048839"(inner ear development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190861|ensembl:ENSMUSG00000040055(gene) refseq:NP_666217.2|ensembl:ENSMUSG00000038949(gene)|ensembl:ENSMUST00000040706(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318 - - - figure legend:Fig. 1. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/15 2014/10/16 rogid:2731PdUhdigL26O4eLKzd3E37Rg10090 rogid:FykY9TEMok4jY9VhfByb+/zCZYk10090 intact-crc:2073A0A44020AEE9|rigid:/bhwfoSb9ONvgF4PtlMv2TVisCU false - necessary binding region:503-631 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8R0H9 uniprotkb:Q8CBC4-3 intact:EBI-2616212|uniprotkb:Q3U2N1|ensembl:ENSMUSP00000035992 intact:EBI-2615407 psi-mi:gga1_mouse(display_long)|uniprotkb:Gga1(gene name)|psi-mi:Gga1(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0018"(two hybrid) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2616235|imex:IM-19064-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666041.1|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q8R0H9|ensembl:ENSMUSG00000033128(gene)|ensembl:ENSMUST00000041587(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane) intact:EBI-2615382(isoform-parent) - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/15 2014/10/16 rogid:IMtckR51G3QqaABGjEfbVq65wyc10090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:9D1B0D00E2BE8DB8|rigid:A4zrITTkXrP2ywR9zFZIiGBzpjM false necessary binding region:1-260(IPR002014) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P5E6 uniprotkb:Q8CBC4-3 intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581 intact:EBI-2615407 psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0018"(two hybrid) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2616274|imex:IM-19064-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6 intact:EBI-2615382(isoform-parent) - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/15 2014/10/16 rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:F1E1516DA7F6A4DE|rigid:WSdAwP9Uebb+msPkSDYxiszh1dc false necessary binding region:1-278(IPR002014) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8CBC4-3 uniprotkb:P28229 intact:EBI-2615407 intact:EBI-1767271|ensembl:ENSMUSP00000066901|ensembl:ENSMUSP00000090228|ensembl:ENSMUSP00000102690 psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:cxg1_mouse(display_long)|uniprotkb:Gjc1(gene name)|psi-mi:Gjc1(display_short)|uniprotkb:Cxn-45(gene name synonym)|uniprotkb:Gja7(gene name synonym)|uniprotkb:Gap junction alpha-7 protein(gene name synonym)|uniprotkb:Connexin-45(gene name synonym) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616063|imex:IM-19064-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2615382(isoform-parent) refseq:XP_011247038.1|refseq:NP_001152854.1|refseq:NP_001152855.1|refseq:NP_032148.1|refseq:XP_006532289.1|refseq:XP_006532290.1|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0045202"(synapse)|go:"GO:0048468"(cell development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0086053"(AV node cell to bundle of His cell communication by electrical coupling)|go:"GO:0086077"(gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling)|interpro:IPR000500(Connexins)|interpro:IPR002265("Gap junction alpha-6 protein (Cx45)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-112303|reactome:R-MMU-190861|ensembl:ENSMUSG00000034520(gene)|ensembl:ENSMUST00000068933(transcript)|ensembl:ENSMUST00000092567(transcript)|ensembl:ENSMUST00000107075(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005216"(ion channel activity)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007268"(chemical synaptic transmission) - - - figure legend:Fig. 2. A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 rogid:Nhhg8t9MCvbOYs/G8HU7FqLNrK010090 intact-crc:F0D7A19FBEC704CB|rigid:LHxD5rv6IEi0djP9yCpawGftQN8 false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8R0H9 uniprotkb:Q8CBC4-3 intact:EBI-2616212|uniprotkb:Q3U2N1|ensembl:ENSMUSP00000035992 intact:EBI-2615407 psi-mi:gga1_mouse(display_long)|uniprotkb:Gga1(gene name)|psi-mi:Gga1(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616282|imex:IM-19064-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666041.1|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q8R0H9|ensembl:ENSMUSG00000033128(gene)|ensembl:ENSMUST00000041587(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane) intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 5. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:IMtckR51G3QqaABGjEfbVq65wyc10090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:C0E1731E6421D96F|rigid:A4zrITTkXrP2ywR9zFZIiGBzpjM false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8CBC4-3 uniprotkb:Q6P5E6 intact:EBI-2615407 intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581 psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616297|imex:IM-19064-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2615382(isoform-parent) refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6 - - - figure legend:Fig. 5. C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090 intact-crc:37510E8966FE037E|rigid:WSdAwP9Uebb+msPkSDYxiszh1dc false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q00977 uniprotkb:Q8CBC4-3 intact:EBI-2615361|ensembl:ENSMUSP00000054343 intact:EBI-2615407 psi-mi:cxb2_mouse(display_long)|uniprotkb:Gjb2(gene name)|psi-mi:Gjb2(display_short)|uniprotkb:Cxn-26(gene name synonym)|uniprotkb:Connexin-26(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616427|imex:IM-19064-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032151.1|ensembl:ENSMUST00000055698(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|ensembl:ENSMUSG00000046352(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190872 intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:avaPYwYewnqkZhtjfJmYRNpKjtw10090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:A3A128D15E81B9F6|rigid:2NjxjimUjpeiylRMApm38xL0jwE false 35s radiolabel:?-? sufficient binding region:1-362|glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P70689 uniprotkb:Q8CBC4-3 intact:EBI-2615416|ensembl:ENSMUSP00000035630 intact:EBI-2615407 psi-mi:cxb6_mouse(display_long)|uniprotkb:Gjb6(gene name)|psi-mi:Gjb6(display_short)|uniprotkb:Cxn-30(gene name synonym)|uniprotkb:Connexin-30(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616436|imex:IM-19064-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258592.1|refseq:NP_001010937.1|refseq:XP_006518623.1|refseq:XP_006518624.1|ensembl:ENSMUST00000039380(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048839"(inner ear development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190861|ensembl:ENSMUSG00000040055(gene) intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:2731PdUhdigL26O4eLKzd3E37Rg10090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:E2AB01C38066DEEB|rigid:0pLrNV9bKK0UyK0y8iU3+mMH6uQ false 35s radiolabel:?-? sufficient binding region:1-362|glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P28231 uniprotkb:Q8CBC4-3 intact:EBI-1767245|ensembl:ENSMUSP00000046755|ensembl:ENSMUSP00000101697 intact:EBI-2615407 psi-mi:cxb3_mouse(display_long)|uniprotkb:Gjb3(gene name)|psi-mi:Gjb3(display_short)|uniprotkb:Cxn-31(gene name synonym)|uniprotkb:Connexin-31(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616445|imex:IM-19064-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153484.1|refseq:NP_032152.1|ensembl:ENSMUSG00000042367(gene)|ensembl:ENSMUST00000046532(transcript)|ensembl:ENSMUST00000106091(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR000500(Connexins)|interpro:IPR002269("Gap junction beta-3 protein (Cx31)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190861 intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:pxtYKJtDRr/X6MfOFhQrOeT3c+410090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:D60050743F87E7AB|rigid:F8fC49XSSpN7mFKZRwqoxaF+x6k false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P28230 uniprotkb:Q8CBC4-3 intact:EBI-2616081|ensembl:ENSMUSP00000062723|ensembl:ENSMUSP00000113516|ensembl:ENSMUSP00000113904 intact:EBI-2615407 psi-mi:cxb1_mouse(display_long)|uniprotkb:Gjb1(gene name)|psi-mi:Gjb1(display_short)|uniprotkb:Cxn-32(gene name synonym)|uniprotkb:Connexin-32(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616457|imex:IM-19064-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032150.2|refseq:NP_001289425.1|refseq:NP_001289426.1|refseq:NP_001289427.1|ensembl:ENSMUSG00000047797(gene)|ensembl:ENSMUST00000052130(transcript)|ensembl:ENSMUST00000119080(transcript)|ensembl:ENSMUST00000119190(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015868"(purine ribonucleotide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1905867"(epididymis development)|interpro:IPR000500(Connexins)|interpro:IPR002267("Gap junction beta-1 protein (Cx32)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-190704|go:"GO:0005921"(gap junction) intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:x3V62arafAbrMJrHBVC9hCzMfv410090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:E421671A0AF6E60A|rigid:004zWnda0Gpuf9ilD7Rk08iOyaI false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P23242 uniprotkb:Q8CBC4-3 intact:EBI-298630|ensembl:ENSMUSP00000064536|ensembl:ENSMUSP00000151620|uniprotkb:Q544I7|uniprotkb:Q8CE05 intact:EBI-2615407 psi-mi:cxa1_mouse(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2616473|imex:IM-19064-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005771"(multivesicular body)|go:"GO:0030054"(cell junction)|ensembl:ENSMUSG00000050953(gene)|ensembl:ENSMUST00000068581(transcript)|ensembl:ENSMUST00000220069(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0005882"(intermediate filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0005886"(plasma membrane)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007154"(cell communication)|go:"GO:0016020"(membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0070160"(tight junction)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P23242|reactome:R-MMU-190840|reactome:R-MMU-190861|reactome:R-MMU-190873|reactome:R-MMU-191650|reactome:R-MMU-196025|reactome:R-MMU-9013406|go:"GO:1905867"(epididymis development)|refseq:NP_034418.1|dip:DIP-29207N intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:y7Yg1+W6tlVZnaRALQBCWQppVf010090 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:CAB4F2D5007C71B8|rigid:+m4gzfGYo4Mrs6k0kDmGrjoieBk false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8CBC4-3 uniprotkb:P21994 intact:EBI-2615407 intact:EBI-2616119|ensembl:ENSRNOP00000011711 psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:cxb2_rat(display_long)|uniprotkb:Gjb2(gene name)|psi-mi:Gjb2(display_short)|uniprotkb:Cxn-26(gene name synonym)|uniprotkb:Connexin-26(gene name synonym) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2638420|imex:IM-19064-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2615382(isoform-parent) rgd:728891|refseq:NP_001004099.1|refseq:XP_017455254.1|ensembl:ENSRNOG00000008855(gene)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|ensembl:ENSRNOT00000011711(transcript)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-RNO-190872|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|dip:DIP-48901N - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 rogid:b1SvjSjCB8BjzqIjEkaJHJVb60010116 intact-crc:0CB035EBAD4BA139|rigid:E3bINDZGkmDBznUk2nr6fDkIjck false glutathione s tranferase tag:?-?|sufficient binding region:1-362 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P21994 uniprotkb:Q8CBC4-3 intact:EBI-2616119|ensembl:ENSRNOP00000011711 intact:EBI-2615407 psi-mi:cxb2_rat(display_long)|uniprotkb:Gjb2(gene name)|psi-mi:Gjb2(display_short)|uniprotkb:Cxn-26(gene name synonym)|uniprotkb:Connexin-26(gene name synonym) psi-mi:q8cbc4-3(display_long)|uniprotkb:Cnst(gene name)|psi-mi:Cnst(display_short) psi-mi:"MI:0096"(pull down) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2616142|imex:IM-19064-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:728891|refseq:NP_001004099.1|refseq:XP_017455254.1|ensembl:ENSRNOG00000008855(gene)|go:"GO:0002931"(response to ischemia)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0055085"(transmembrane transport)|ensembl:ENSRNOT00000011711(transcript)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1905867"(epididymis development)|go:"GO:1990349"(gap junction-mediated intercellular transport)|interpro:IPR000500(Connexins)|interpro:IPR002268("Gap junction beta-2 protein (Cx26)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-RNO-190872|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|dip:DIP-48901N intact:EBI-2615382(isoform-parent) - - - figure legend:Fig. 2. C|antibodies:specific rabbit polyclonal antibody against Gjb2 for the western blot|comment:No band was detected in the GST-consortin lane, indicating that membrane-inserted Grb2 does not interact with the isoform 3 of consortin.|delivery method:P21994 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/15 2014/10/16 rogid:b1SvjSjCB8BjzqIjEkaJHJVb60010116 rogid:3OgwIYekqgT7LyU2Mv1NNL9+gNY10090 intact-crc:FB1AF98092EFE3BD|rigid:E3bINDZGkmDBznUk2nr6fDkIjck false - sufficient binding region:1-362|glutathione s tranferase tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P23242 uniprotkb:Q6PJW8 intact:EBI-298630|ensembl:ENSMUSP00000064536|ensembl:ENSMUSP00000151620|uniprotkb:Q544I7|uniprotkb:Q8CE05 intact:EBI-750390|uniprotkb:Q5VSY9|uniprotkb:Q5VTM7|uniprotkb:Q8IYA9|uniprotkb:Q8N3L5|uniprotkb:Q8NB09|uniprotkb:Q8TEI2|uniprotkb:Q96MR5|ensembl:ENSP00000355470 psi-mi:cxa1_mouse(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym) psi-mi:cnst_human(display_long)|uniprotkb:CNST(gene name)|psi-mi:CNST(display_short)|uniprotkb:C1orf71(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2616165|imex:IM-19064-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005771"(multivesicular body)|go:"GO:0030054"(cell junction)|ensembl:ENSMUSG00000050953(gene)|ensembl:ENSMUST00000068581(transcript)|ensembl:ENSMUST00000220069(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0005882"(intermediate filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0005886"(plasma membrane)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007154"(cell communication)|go:"GO:0016020"(membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0070160"(tight junction)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P23242|reactome:R-MMU-190840|reactome:R-MMU-190861|reactome:R-MMU-190873|reactome:R-MMU-191650|reactome:R-MMU-196025|reactome:R-MMU-9013406|go:"GO:1905867"(epididymis development)|refseq:NP_034418.1|dip:DIP-29207N refseq:NP_001132931.1|refseq:NP_689822.2|refseq:XP_005273138.2|refseq:XP_011542412.1|refseq:XP_011542413.1|ensembl:ENSG00000162852(gene)|ensembl:ENST00000366513(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318|go:"GO:0019902"(phosphatase binding) - - - figure legend:Fig. 2. D|delivery method:P23242 transfection|antibodies:"Rabbit polyclonal antibodies against CNST and Gja1 for the immunoblot. Monoclonal antibodies against Gja1 for the co-immunoprecipitation (IF1, CT1, P2D12)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/03/15 2014/10/16 rogid:y7Yg1+W6tlVZnaRALQBCWQppVf010090 rogid:N60V+qHcb7zp0PVzK1VerUEsrLg9606 intact-crc:DDA49261A4BCE30D|rigid:2dddMEpSQEGOkPixPybMOkSk008 false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q8R0H9 uniprotkb:Q6PJW8 intact:EBI-2616212|uniprotkb:Q3U2N1|ensembl:ENSMUSP00000035992 intact:EBI-750390|uniprotkb:Q5VSY9|uniprotkb:Q5VTM7|uniprotkb:Q8IYA9|uniprotkb:Q8N3L5|uniprotkb:Q8NB09|uniprotkb:Q8TEI2|uniprotkb:Q96MR5|ensembl:ENSP00000355470 psi-mi:gga1_mouse(display_long)|uniprotkb:Gga1(gene name)|psi-mi:Gga1(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym) psi-mi:cnst_human(display_long)|uniprotkb:CNST(gene name)|psi-mi:CNST(display_short)|uniprotkb:C1orf71(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2616324|imex:IM-19064-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666041.1|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q8R0H9|ensembl:ENSMUSG00000033128(gene)|ensembl:ENSMUST00000041587(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane) refseq:NP_001132931.1|refseq:NP_689822.2|refseq:XP_005273138.2|refseq:XP_011542412.1|refseq:XP_011542413.1|ensembl:ENSG00000162852(gene)|ensembl:ENST00000366513(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318|go:"GO:0019902"(phosphatase binding) - - - figure legend:Fig. 5. B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/03/15 2014/10/16 rogid:IMtckR51G3QqaABGjEfbVq65wyc10090 rogid:N60V+qHcb7zp0PVzK1VerUEsrLg9606 intact-crc:2AF156C3D9BE7750|rigid:oozeNyU2byXsBlcMM/EBEwQJRPc false myc tag:?-? - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6PJW8 uniprotkb:Q6P5E6 intact:EBI-750390|uniprotkb:Q5VSY9|uniprotkb:Q5VTM7|uniprotkb:Q8IYA9|uniprotkb:Q8N3L5|uniprotkb:Q8NB09|uniprotkb:Q8TEI2|uniprotkb:Q96MR5|ensembl:ENSP00000355470 intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581 psi-mi:cnst_human(display_long)|uniprotkb:CNST(gene name)|psi-mi:CNST(display_short)|uniprotkb:C1orf71(gene name synonym) psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) del et al. (2010) pubmed:19864490|imex:IM-19064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2616339|imex:IM-19064-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001132931.1|refseq:NP_689822.2|refseq:XP_005273138.2|refseq:XP_011542412.1|refseq:XP_011542413.1|ensembl:ENSG00000162852(gene)|ensembl:ENST00000366513(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318|go:"GO:0019902"(phosphatase binding) refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6 - - - figure legend:Fig. 5. D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/03/15 2014/10/16 rogid:N60V+qHcb7zp0PVzK1VerUEsrLg9606 rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090 intact-crc:AECF762B0434E5ED|rigid:nyybrX7RkP0tY3m9AwesTEODcf8 false - myc tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)