#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:59639"	uniprotkb:Q66HM2	intact:EBI-2696342	intact:EBI-2255846|ensembl:ENSRNOP00000060992	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:q66hm2_rat(display_long)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:71015|refseq:NP_112270.2|ensembl:ENSRNOG00000019534(gene)|ensembl:ENSRNOT00000064254(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:Q66HM2	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:FUY6sVuoA7kEnOWKy6KX7J+J3+M10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q4FZU2	intact:EBI-2696342	intact:EBI-2696520	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:k2c6a_rat(display_long)|uniprotkb:Krt6a(gene name)|psi-mi:Krt6a(display_short)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR018039|interpro:IPR003054(Type II keratin)|rgd:1588056|refseq:NP_001094477.1|interpro:IPR032444|interpro:IPR039008|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:cfDKwCGnXrIKUTkOuuKK1HwmyHM10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P16086	intact:EBI-2696342	intact:EBI-2255997|uniprotkb:O88663|uniprotkb:P70477|ensembl:ENSRNOP00000042382	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:sptn1_rat(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621714|refseq:NP_741984.2|ensembl:ENSRNOG00000015396(gene)|ensembl:ENSRNOT00000045827(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0008091"(spectrin)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16086|rcsb pdb:3THK|reactome:R-RNO-264870|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-9013420|reactome:R-RNO-9013424	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:3Tj95Pgv62omEnsaMAG3bfLLXsM10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P06686	intact:EBI-2696342	intact:EBI-2649928|ensembl:ENSRNOP00000054947	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:at1a2_rat(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2168|refseq:NP_036637.1|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0040011"(locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06686|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0035725"(sodium ion transmembrane transport)|ensembl:ENSRNOG00000007290(gene)|ensembl:ENSRNOT00000058143(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6P6R2	intact:EBI-2696342	intact:EBI-918983|ensembl:ENSRNOP00000008980	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dldh_rat(display_long)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:735073|refseq:NP_955417.1|ensembl:ENSRNOG00000006364(gene)|ensembl:ENSRNOT00000008980(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-6783984|reactome:R-RNO-70268|reactome:R-RNO-70895|reactome:R-RNO-71064|reactome:R-RNO-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:nPQaWMwZUe3ppKl4G/qGuUYyTAE10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P04636	intact:EBI-2696342	intact:EBI-349293|ensembl:ENSRNOP00000001958|uniprotkb:Q6GSM4	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:mdhm_rat(display_long)|uniprotkb:Mdh2(gene name)|psi-mi:Mdh2(display_short)|uniprotkb:Mor1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:619719|refseq:NP_112413.2|ensembl:ENSRNOG00000001440(gene)|ensembl:ENSRNOT00000001958(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0016615"(malate dehydrogenase activity)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P04636|reactome:R-RNO-70263|reactome:R-RNO-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:Sa/YbZ/4mSQwdbOEyVs+4XfoUMg10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P09606	intact:EBI-2696342	intact:EBI-349265|uniprotkb:Q6P7Q9|ensembl:ENSRNOP00000065890	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:glna_rat(display_long)|uniprotkb:Glns(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2710|refseq:NP_058769.4|ensembl:ENSRNOG00000049560(gene)|ensembl:ENSRNOT00000075480(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P09606|go:"GO:0043005"(neuron projection)|reactome:R-RNO-210455|reactome:R-RNO-8964539|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:VN1L4Kl9yF9dxmvXpA3f1prv0tw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P48500	intact:EBI-2696342	intact:EBI-917606|uniprotkb:A0JN18|uniprotkb:Q6P793|ensembl:ENSRNOP00000020647|ensembl:ENSRNOP00000067409	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tpis_rat(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3896|refseq:NP_075211.2|ensembl:ENSRNOG00000015290(gene)|ensembl:ENSRNOG00000050669(gene)|ensembl:ENSRNOT00000020647(transcript)|ensembl:ENSRNOT00000071439(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P48500|reactome:R-RNO-70171|reactome:R-RNO-70263	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:W10iJfxiYxwYl5C2aji6DCDhpBc10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P07335	intact:EBI-2696342	intact:EBI-2255838|uniprotkb:A0JPK7|uniprotkb:Q499P7|uniprotkb:Q5PPJ5|uniprotkb:Q6IRE0|uniprotkb:Q6P139|ensembl:ENSRNOP00000015122	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:kcrb_rat(display_long)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)|uniprotkb:Ckb(gene name)|psi-mi:Ckb(display_short)|uniprotkb:Ckbb(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:B-CK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2357|refseq:NP_036661.3|ensembl:ENSRNOG00000010872(gene)|ensembl:ENSRNOT00000015122(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07335|reactome:R-RNO-71288|reactome:R-RNO-9696264	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:b4DcUjJsdE7p+LN3DvdMXRUveEw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P47858	intact:EBI-2696342	intact:EBI-349356|uniprotkb:Q63736	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pfkam_rat(display_long)|uniprotkb:Pfkm(gene name)|psi-mi:Pfkm(display_short)|uniprotkb:Pfk-m(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:6-phosphofructokinase type A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:68419|refseq:NP_113903.1|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR022953|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR000023(Phosphofructokinase)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008443"(phosphofructokinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|reactome:R-RNO-70171|mint:P47858|interpro:IPR035966|interpro:IPR041914	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:y1QKLAwU/FRyflZI8xnOKZsKOvc10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P53534	intact:EBI-2696342	intact:EBI-2696349	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pygb_rat(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR035090|rgd:3460|refseq:NP_037320.1|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|mint:P53534|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|reactome:R-RNO-6798695	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:WcV4oiXMS78KKpVSzVnziBt5uD810116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P26284	intact:EBI-2696342	intact:EBI-1163773	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:odpa_rat(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|rgd:3286|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|interpro:IPR029061|mint:P26284	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:ZS2XIIvPJLzbaoUBw21HHJw6gcw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P04797	intact:EBI-2696342	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9ER34	intact:EBI-2696342	intact:EBI-919008|uniprotkb:Q6P6V3|ensembl:ENSRNOP00000029144	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:acon_rat(display_long)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)|uniprotkb:Citrate hydro-lyase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621360|refseq:NP_077374.2|ensembl:ENSRNOG00000024128(gene)|ensembl:ENSRNOT00000038612(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q9ER34|reactome:R-RNO-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:Nk+zXn0ahm2Fy+jiP75Yp9gWYHk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q8VHF5	intact:EBI-2696342	intact:EBI-349285	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:cisy_rat(display_long)|uniprotkb:Cs(gene name)|psi-mi:Cs(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620330|refseq:NP_570111.1|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR019810|interpro:IPR010109(Citrate synthase, eukaryotic)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0046912"(acyltransferase, acyl groups converted into alkyl on transfer)|reactome:R-RNO-71403|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|mint:Q8VHF5|interpro:IPR036969	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:3c3FZwuqQofmxnE7JYrd/zmEHec10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P04764	intact:EBI-2696342	intact:EBI-915852|uniprotkb:Q66HI3|uniprotkb:Q6AYV3|uniprotkb:Q6P504|ensembl:ENSRNOP00000024106|ensembl:ENSRNOP00000073191	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:enoa_rat(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2553|refseq:NP_001103378.1|refseq:NP_036686.2|ensembl:ENSRNOG00000017895(gene)|ensembl:ENSRNOT00000024106(transcript)|ensembl:ENSRNOT00000081579(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P04764|reactome:R-RNO-70171|reactome:R-RNO-70263	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:JPjYBxy1gOmhfZso6+adhg5N8UM10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P25286	intact:EBI-2696342	intact:EBI-2024887|intact:EBI-11702593	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:vpp1_rat(display_long)|uniprotkb:Atp6v0a1(gene name)|psi-mi:Atp6v0a1(display_short)|uniprotkb:Atp6n1(gene name synonym)|uniprotkb:Vpp1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR026028|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|rgd:68405|refseq:NP_113792.2|mint:P25286|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:1901998"(toxin transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-983712|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:M+mzcb5KThafTTcJpimDmH5I4fk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P35704	intact:EBI-2696342	intact:EBI-917371|uniprotkb:Q6PDV3	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:prdx2_rat(display_long)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3838|refseq:NP_058865.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|mint:P35704|interpro:IPR013766(Thioredoxin domain)|refseq:XP_006255306.1|interpro:IPR036249|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|reactome:R-RNO-3299685|reactome:R-RNO-5628897	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:pAorkTLST5+rViOjvDlhw2edzQE10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P34058	intact:EBI-2696342	intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q3MHS9	intact:EBI-2696342	intact:EBI-2696854|ensembl:ENSRNOP00000001227	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:q3mhs9_rat(display_long)|uniprotkb:Cct6a(gene name)|psi-mi:Cct6a(display_short)|uniprotkb:rCG_21714(orf name)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1304763|refseq:NP_001028856.1|ensembl:ENSRNOG00000000923(gene)|ensembl:ENSRNOT00000001227(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q3MHS9|reactome:R-RNO-390471|reactome:R-RNO-6814122|reactome:R-RNO-9013418	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:lA9XgEkRYlAVdN+LCAhQh3u8fNg10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q5XIM9	intact:EBI-2696342	intact:EBI-920517|ensembl:ENSRNOP00000029234	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tcpb_rat(display_long)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cctb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1359143|refseq:NP_001005905.1|ensembl:ENSRNOG00000021317(gene)|ensembl:ENSRNOT00000037946(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q5XIM9|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6798695|reactome:R-RNO-6814122|reactome:R-RNO-9013418|reactome:R-RNO-9013422	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:JKr4ca8SpJ/EnpoJsDazwn8L6hc10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P82995	intact:EBI-2696342	intact:EBI-919629|uniprotkb:Q91XW0|ensembl:ENSRNOP00000009556|ensembl:ENSRNOP00000075715	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hs90a_rat(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Hsp86(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_008763191.1|rgd:631409|refseq:NP_786937.1|ensembl:ENSRNOG00000007219(gene)|ensembl:ENSRNOG00000059714(gene)|ensembl:ENSRNOT00000009556(transcript)|ensembl:ENSRNOT00000086310(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042220"(response to cocaine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P82995|reactome:R-RNO-1227986|reactome:R-RNO-1474151|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-203615|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-399954|reactome:R-RNO-4420097|reactome:R-RNO-5218920|reactome:R-RNO-5620912|reactome:R-RNO-5675482|reactome:R-RNO-6798695|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8863795|reactome:R-RNO-8939211|reactome:R-RNO-9009391|reactome:R-RNO-9013418|reactome:R-RNO-9018519|reactome:R-RNO-9652282	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:tqpvMNNqRR42cL/lpXrgcqJh0NE10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P63018	intact:EBI-2696342	intact:EBI-433431|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q4FZY7|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hsp7c_rat(display_long)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621725|refseq:NP_077327.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008380"(RNA splicing)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0010045"(response to nickel cation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0044849"(estrous cycle)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990834"(response to odorant)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1CKR|rcsb pdb:1Q2G|rcsb pdb:1UD0|rcsb pdb:2V7Z|rcsb pdb:7HSC|mint:P63018|dip:DIP-33262N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62260	intact:EBI-2696342	intact:EBI-356462|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSRNOP00000007100	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433e_rat(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)|uniprotkb:Mitochondrial import stimulation factor L subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:62000|refseq:NP_113791.1|ensembl:ENSRNOG00000005290(gene)|ensembl:ENSRNOT00000007100(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62260|reactome:R-RNO-111447|reactome:R-RNO-2028269|reactome:R-RNO-205025|reactome:R-RNO-2565942|reactome:R-RNO-3371453|reactome:R-RNO-3371511|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-8876198|dip:DIP-37260N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62161	intact:EBI-2696342	intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P54311	intact:EBI-2696342	intact:EBI-917779|uniprotkb:Q6Q8B1|uniprotkb:Q9QWG8|ensembl:ENSRNOP00000044340	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gbb1_rat(display_long)|uniprotkb:Transducin beta chain 1(gene name synonym)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2718|refseq:NP_112249.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|ensembl:ENSRNOT00000041789(transcript)|ensembl:ENSRNOG00000016638(gene)|refseq:XP_008762557.1|refseq:XP_006239579.1|refseq:XP_017448634.1|refseq:XP_017448635.1|refseq:XP_017448636.1|refseq:XP_017448637.1|refseq:XP_017448638.1|dip:DIP-37029N|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P54311|rcsb pdb:3SN6|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-2485179|reactome:R-RNO-381676|reactome:R-RNO-381753|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P61983	intact:EBI-2696342	intact:EBI-359821|uniprotkb:A0JPM0|uniprotkb:O70457|uniprotkb:Q9UDP2|uniprotkb:P35214|uniprotkb:Q9UN99|ensembl:ENSRNOP00000001954|ensembl:ENSRNOP00000069671	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433g_rat(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:62002|refseq:NP_062249.1|ensembl:ENSRNOG00000001436(gene)|ensembl:ENSRNOT00000001954(transcript)|ensembl:ENSRNOT00000084730(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61983|reactome:R-RNO-111447|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-9614399|refseq:XP_006249246.2	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P13233	intact:EBI-2696342	intact:EBI-2640672|uniprotkb:Q4V796|uniprotkb:Q64575|ensembl:ENSRNOP00000023875	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:cn37_rat(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2368|refseq:NP_036941.1|ensembl:ENSRNOG00000017496(gene)|ensembl:ENSRNOT00000023872(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P13233|rcsb pdb:2ILX	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:+0AAow8yyo0d6aKTghtTmcS2SZw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P63102	intact:EBI-2696342	intact:EBI-354758|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q52KK1|uniprotkb:Q6IRF4|ensembl:ENSRNOP00000030885	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433z_rat(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Msfs1(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Mitochondrial import stimulation factor S1 subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3980|refseq:NP_037143.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63102|reactome:R-RNO-111447|reactome:R-RNO-3769402|reactome:R-RNO-392517|reactome:R-RNO-430116|reactome:R-RNO-450604|reactome:R-RNO-512988|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9013700|reactome:R-RNO-9614399|refseq:XP_006241591.1|ensembl:ENSRNOG00000008195(gene)|ensembl:ENSRNOT00000035628(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|dip:DIP-36916N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q5XIM7	intact:EBI-2696342	intact:EBI-2696809|ensembl:ENSRNOP00000044454	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:syk_rat(display_long)|uniprotkb:Kars1(gene name)|psi-mi:Kars1(display_short)|uniprotkb:Kars(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1359653|refseq:NP_001006968.1|ensembl:ENSRNOG00000019456(gene)|ensembl:ENSRNOT00000046126(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0010165"(response to X-ray)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|interpro:IPR034762|interpro:IPR044136	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:XcN4ryJStKwX7/EOh2M+VODQON810116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62083	intact:EBI-2696342	intact:EBI-354370|uniprotkb:P24818|uniprotkb:P23821|ensembl:ENSRNOP00000011333|ensembl:ENSRNOP00000075995	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:rs7_rat(display_long)|uniprotkb:Rps7(gene name)|psi-mi:Rps7(display_short)|uniprotkb:S8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_113758.2|refseq:XP_002726666.2|refseq:XP_002729622.2|rgd:61907|ensembl:ENSRNOG00000008551(gene)|ensembl:ENSRNOT00000011333(transcript)|ensembl:ENSRNOT00000092867(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62083|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|go:"GO:0006412"(translation)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6AY09	intact:EBI-2696342	intact:EBI-1638443|ensembl:ENSRNOP00000015518	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrh2_rat(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1549784|refseq:NP_001014041.1|refseq:XP_006257281.1|refseq:XP_006257282.1|refseq:XP_006257283.1|ensembl:ENSRNOG00000011661(gene)|ensembl:ENSRNOT00000015518(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:Q6AY09|reactome:R-RNO-72163|go:"GO:0005654"(nucleoplasm)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:iYxEIXbVEciSTaqi1m4uhyPppRE10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9QX81	intact:EBI-2696342	intact:EBI-2696787|ensembl:ENSRNOP00000004885|ensembl:ENSRNOP00000069174	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:q9qx81_rat(display_long)|uniprotkb:Hnrnpab(gene name)|psi-mi:Hnrnpab(display_short)|uniprotkb:LOC103689931(gene name synonym)|uniprotkb:rCG_34663(orf name)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006246407.1|rgd:9343685|refseq:XP_003750865.1|rgd:69255|ensembl:ENSRNOG00000003645(gene)|ensembl:ENSRNOG00000046272(gene)|ensembl:ENSRNOT00000004885(transcript)|ensembl:ENSRNOT00000086193(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030425"(dendrite)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1904580"(regulation of intracellular mRNA localization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071230"(cellular response to amino acid stimulus)|refseq:XP_017459539.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:fORngGLYExp3KF8SyyQlL1Hl9m810116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6URK4	intact:EBI-2696342	intact:EBI-2696754|uniprotkb:Q6URK3|ensembl:ENSRNOP00000069876	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:roa3_rat(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:727807|refseq:NP_001104764.1|refseq:NP_001104765.1|refseq:NP_937765.1|refseq:XP_008760133.1|refseq:XP_008760134.1|ensembl:ENSRNOG00000052968(gene)|ensembl:ENSRNOT00000078872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q6URK4|reactome:R-RNO-72163	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62630	intact:EBI-2696342	intact:EBI-917951|uniprotkb:P20001|uniprotkb:Q5BJW8|uniprotkb:Q64718|uniprotkb:Q78ED4|ensembl:ENSRNOP00000013608	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ef1a1_rat(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:67387|refseq:NP_787032.1|ensembl:ENSRNOG00000009439(gene)|ensembl:ENSRNOT00000013608(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P62630|reactome:R-RNO-156842|reactome:R-RNO-3371511|reactome:R-RNO-6798695|reactome:R-RNO-8876725	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:85G9Uje743KzA02bB/rmKuq2HbU10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9JJ54	intact:EBI-2696342	intact:EBI-2696704|uniprotkb:Q9JJ51|uniprotkb:Q9JJ52|uniprotkb:Q9JJ53|ensembl:ENSRNOP00000046491|uniprotkb:G3V9G2|uniprotkb:P17132	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrpd_rat(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620365|refseq:NP_001076008.1|refseq:NP_001076009.1|refseq:NP_001076010.1|refseq:NP_077380.2|ensembl:ENSRNOG00000002292(gene)|ensembl:ENSRNOT00000047840(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007420"(brain development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032355"(response to estradiol)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q9JJ54|reactome:R-RNO-450408|reactome:R-RNO-72163	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:fV91RKUcQMG97Am2q0D9jmps1Uw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P04256	intact:EBI-2696342	intact:EBI-1647150	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:roa1_rat(display_long)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:69234|refseq:NP_058944.1|interpro:IPR021662|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|reactome:R-RNO-6803529|reactome:R-RNO-72163|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904577"(cellular response to tunicamycin)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990826"(nucleoplasmic periphery of the nuclear pore complex)|go:"GO:1990904"(ribonucleoprotein complex)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:uiZpkRykRJxT0w/mMET4HS1KKYA10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:B5DEN5	intact:EBI-2696342	intact:EBI-2640627|ensembl:ENSRNOP00000036882	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:b5den5_rat(display_long)|uniprotkb:Eef1b2(gene name)|psi-mi:Eef1b2(display_short)|uniprotkb:rCG_22471(orf name)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1311415|refseq:NP_001102269.1|ensembl:ENSRNOG00000024186(gene)|ensembl:ENSRNOT00000034740(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:B5DEN5|reactome:R-RNO-156842	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:u9Z0/lB618WDZdrKh+UfuFX0nEk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62909	intact:EBI-2696342	intact:EBI-432553|uniprotkb:P17073|uniprotkb:P47933|ensembl:ENSRNOP00000023935	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:rs3_rat(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:619888|refseq:NP_001009239.1|ensembl:ENSRNOG00000017418(gene)|ensembl:ENSRNOT00000023935(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018280|interpro:IPR036419|mint:P62909|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P52296	intact:EBI-2696342	intact:EBI-917731|intact:EBI-11702595	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:imb1_rat(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|reactome:R-RNO-140342|reactome:R-RNO-1655829|reactome:R-RNO-6798695|reactome:R-RNO-909733|rgd:2909|refseq:NP_058759.1|mint:P52296|dip:DIP-37024N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:i8sGTTT4N+V1jz6fLjdodopKXfQ10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q7TP47	intact:EBI-2696342	intact:EBI-919386|ensembl:ENSRNOP00000048433	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrpq_rat(display_long)|uniprotkb:Syncrip(gene name)|psi-mi:Syncrip(display_short)|uniprotkb:Hnrpq(gene name synonym)|uniprotkb:Ab2-339(orf name)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG077(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1305683|refseq:NP_001041381.1|ensembl:ENSRNOG00000000204(gene)|ensembl:ENSRNOT00000041655(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090367"(negative regulation of mRNA modification)|go:"GO:0097452"(GAIT complex)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|mint:Q7TP47	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:AETEMoY8iTxnVf1mtSgs1TKDwwk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q5U328	intact:EBI-2696342	intact:EBI-2696685|ensembl:ENSRNOP00000024712	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:q5u328_rat(display_long)|uniprotkb:rCG_23860(orf name)|uniprotkb:Ncl(gene name)|psi-mi:Ncl(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3153|refseq:NP_036881.2|ensembl:ENSRNOG00000018273(gene)|ensembl:ENSRNOT00000024712(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:guCo9dDvy2ozRrpIKWoIRr7dnOY10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q5RJQ4	intact:EBI-2696342	intact:EBI-2696664|ensembl:ENSRNOP00000059450	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:sir2_rat(display_long)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621481|refseq:NP_001008369.1|ensembl:ENSRNOG00000020102(gene)|ensembl:ENSRNOT00000064153(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007417"(central nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q5RJQ4|reactome:R-RNO-2995383	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:yxpJ/hJp1J7pE2ctnECN4j+HkoA10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P97536	intact:EBI-2696342	intact:EBI-918083|ensembl:ENSRNOP00000010720	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:cand1_rat(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:Cand1(gene name)|psi-mi:Cand1(display_short)|uniprotkb:Tip120(gene name synonym)|uniprotkb:Tip120a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620479|refseq:NP_446456.1|ensembl:ENSRNOG00000007834(gene)|ensembl:ENSRNOT00000010720(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:P97536|reactome:R-RNO-6798695|reactome:R-RNO-8951664|reactome:R-RNO-917937	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:AYiE0tEiNw1ias86oxC6CxJm5uo10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P47942	intact:EBI-2696342	intact:EBI-917570|intact:EBI-6096016|ensembl:ENSRNOP00000012996	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dpyl2_rat(display_long)|uniprotkb:Turned on after division 64 kDa protein(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2517|refseq:NP_001099187.1|ensembl:ENSRNOG00000009625(gene)|ensembl:ENSRNOT00000012996(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:P47942|reactome:R-RNO-399956|reactome:R-RNO-437239	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P52303	intact:EBI-2696342	intact:EBI-1040277	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ap1b1_rat(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|rgd:2064|refseq:NP_058973.1|interpro:IPR016342(Adaptor protein complex, beta subunit)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048268"(clathrin coat assembly)|rcsb pdb:1W63|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|interpro:IPR026739|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:P52303	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:oi419FYkBH5Us8n9O9r2j+OvHkM10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P04631	intact:EBI-2696342	intact:EBI-2696631|ensembl:ENSRNOP00000001743	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:s100b_rat(display_long)|uniprotkb:S100b(gene name)|psi-mi:S100b(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3615|refseq:NP_037323.1|refseq:XP_008771090.1|ensembl:ENSRNOG00000001295(gene)|ensembl:ENSRNOT00000001743(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|rcsb pdb:1B4C|rcsb pdb:1DT7|rcsb pdb:1MWN|rcsb pdb:1QLK|rcsb pdb:1SYM|rcsb pdb:1XYD|rcsb pdb:2K7O|reactome:R-RNO-445989|reactome:R-RNO-879415|reactome:R-RNO-933542|go:"GO:0005654"(nucleoplasm)|refseq:XP_017457057.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:BN/sXFZ+oymAQz/00q9FApIbwbw10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q3T1K5	intact:EBI-2696342	intact:EBI-931686|ensembl:ENSRNOP00000072041	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:caza2_rat(display_long)|uniprotkb:Capza2(gene name)|psi-mi:Capza2(display_short)|uniprotkb:CapZ alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1549770|refseq:NP_001009180.1|ensembl:ENSRNOG00000056207(gene)|ensembl:ENSRNOT00000090451(transcript)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:Q3T1K5|rcsb pdb:2KBM|reactome:R-RNO-2132295|reactome:R-RNO-3371497|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-879415|reactome:R-RNO-983231	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:9nxfEbrpHlDtTYwSvHAJvZLLweo10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6IMF3	intact:EBI-2696342	intact:EBI-2696608|uniprotkb:A1L113|uniprotkb:Q63115	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:k2c1_rat(display_long)|uniprotkb:Krt1(gene name)|psi-mi:Krt1(display_short)|uniprotkb:Kb1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1359664|refseq:NP_001008802.2|interpro:IPR018039|interpro:IPR003054(Type II keratin)|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045095"(keratin filament)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|reactome:R-RNO-6798695|reactome:R-RNO-6805567|reactome:R-RNO-6809371	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:GdxRshBQUvc8VtY+8uVfQyAUcbU10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6P9V9	intact:EBI-2696342	intact:EBI-349311|ensembl:ENSRNOP00000070868	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tba1b_rat(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Tuba2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1565476|refseq:NP_001037735.1|ensembl:ENSRNOG00000053468(gene)|ensembl:ENSRNOT00000081355(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR036525|interpro:IPR037103|mint:Q6P9V9|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|interpro:IPR023123|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9013407|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:D4YpuLCXl/S+53qV7P7sF81aARY10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P11442	intact:EBI-2696342	intact:EBI-397997	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:clh1_rat(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2364|refseq:NP_062172.1|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|rcsb pdb:1BPO|rcsb pdb:1C9I|rcsb pdb:1C9L|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:P11442|dip:DIP-36966N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:IRKdzbAIpw7D7qHqyxStNyfI38g10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6AYZ1	intact:EBI-2696342	intact:EBI-2696581|ensembl:ENSRNOP00000068603	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tba1c_rat(display_long)|uniprotkb:Tuba1c(gene name)|psi-mi:Tuba1c(display_short)|uniprotkb:Tuba6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1307226|refseq:NP_001011995.1|refseq:XP_003749402.1|ensembl:ENSRNOG00000021438(gene)|ensembl:ENSRNOT00000033450(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0045121"(membrane raft)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q6AYZ1|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:CtggxXFLCJPeJvHksu32SCSlUfk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P47819	intact:EBI-2696342	intact:EBI-931216|uniprotkb:Q7TQ31|uniprotkb:Q9R1Q3|uniprotkb:Q9Z2S0|uniprotkb:A7REI0|ensembl:ENSRNOP00000032389	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gfap_rat(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:2679|refseq:NP_058705.2|ensembl:ENSRNOG00000002919(gene)|ensembl:ENSRNOT00000034401(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P47819	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:ougdJqiJZjrvDV1vfVnCwcx9cFU10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P85108	intact:EBI-2696342	intact:EBI-2696554|ensembl:ENSRNOP00000023611|ensembl:ENSRNOP00000071729	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tbb2a_rat(display_long)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1588452|refseq:NP_001102589.1|ensembl:ENSRNOG00000017558(gene)|ensembl:ENSRNOT00000023611(transcript)|ensembl:ENSRNOT00000086264(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P85108|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6XD99	intact:EBI-2696342	intact:EBI-2255820	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:q6xd99_rat(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001013148.1|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR041681|rgd:727922|interpro:IPR036872|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098938"(actin cytoskeleton of dendritic spine)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:DMOrxZPtEUgn/gIfEWxOmQsIQmI10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P61765	intact:EBI-2696342	intact:EBI-1029097|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|ensembl:ENSRNOP00000021178	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:stxb1_rat(display_long)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)|uniprotkb:Unc18a(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:rbSec1(gene name synonym)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3785|refseq:NP_037170.1|ensembl:ENSRNOG00000015420(gene)|ensembl:ENSRNOT00000021178(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61765|rcsb pdb:3C98|rcsb pdb:3PUJ|rcsb pdb:4JEH|rcsb pdb:4JEU|rcsb pdb:6LPC|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|refseq:XP_006234001.1|dip:DIP-766N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P46462	intact:EBI-2696342	intact:EBI-399011|ensembl:ENSRNOP00000040121	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tera_rat(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:621595|refseq:NP_446316.1|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|ensembl:ENSRNOG00000034242(gene)|ensembl:ENSRNOT00000046102(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-RNO-9013407|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P46462|reactome:R-RNO-110320|reactome:R-RNO-3371511|reactome:R-RNO-382556|reactome:R-RNO-532668|reactome:R-RNO-5358346|reactome:R-RNO-5689877|reactome:R-RNO-5689896|reactome:R-RNO-6798695	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:U39+QQfgVQlS+3gjtwc3IDz0VME10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P21575	intact:EBI-2696342	intact:EBI-80070|ensembl:ENSRNOP00000041582	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dyn1_rat(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:D100(gene name synonym)|uniprotkb:Dynamin, brain(gene name synonym)|uniprotkb:B-dynamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:71096|refseq:NP_542420.1|ensembl:ENSRNOG00000033835(gene)|ensembl:ENSRNOT00000047921(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P21575|rcsb pdb:2AKA|rcsb pdb:3ZVR|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-437239|reactome:R-RNO-8856828|dip:DIP-30978N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:x9J/VoMgoDFBHadzOhnN3yhTjfs10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P60711	intact:EBI-2696342	intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P34926	intact:EBI-2696342	intact:EBI-631571	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:map1a_rat(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3042|refseq:NP_112257.1|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|mint:P34926|dip:DIP-29265N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:KoMmjz9oNsuegJgHeF2bcf+Ybhs10116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P49432	intact:EBI-2696342	intact:EBI-917663|uniprotkb:Q6AY95|ensembl:ENSRNOP00000010545	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:odpb_rat(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696343|imex:IM-20484-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1359146|refseq:NP_001007621.1|ensembl:ENSRNOG00000007895(gene)|ensembl:ENSRNOT00000010545(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P49432|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|refseq:XP_006251816.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	comment:Identification of rat brain isatin-binding proteins|figure legend:Table 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2010/06/08	2015/03/25	-	rogid:IauZD1wmQ+/x/0WJZxx7kyX8FT410116	intact-crc:4961D976C631A872	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P19157	intact:EBI-2696342	intact:EBI-2309446|uniprotkb:Q8BNY4|ensembl:ENSMUSP00000129565	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gstp1_mouse(display_long)|uniprotkb:Gstp1(gene name)|psi-mi:Gstp1(display_short)|uniprotkb:Gstpib(gene name synonym)|uniprotkb:GST YF-YF(gene name synonym)|uniprotkb:GST-piB(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:Preadipocyte growth factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_038569.1|ensembl:ENSMUSG00000060803(gene)|ensembl:ENSMUST00000169613(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:2000429"(negative regulation of neutrophil aggregation)|go:"GO:2000469"(negative regulation of peroxidase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|mint:P19157|rcsb pdb:1BAY|rcsb pdb:1GLP|rcsb pdb:1GLQ|rcsb pdb:1GSY|rcsb pdb:1GTI|rcsb pdb:2GLR|rcsb pdb:2OA7|rcsb pdb:2OAC|rcsb pdb:2OAD|rcsb pdb:3O76|reactome:R-MMU-156590|reactome:R-MMU-3299685|reactome:R-MMU-6798695	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:hJoMh/r+TgFJqQL95dBmcBsAVn810090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9R111	intact:EBI-2696342	intact:EBI-2308876|ensembl:ENSMUSP00000084882	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:guad_mouse(display_long)|uniprotkb:Gda(gene name)|psi-mi:Gda(display_short)|uniprotkb:Guanine aminohydrolase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034396.1|ensembl:ENSMUSG00000058624(gene)|ensembl:ENSMUST00000087600(transcript)|go:"GO:0000255"(allantoin metabolic process)|go:"GO:0005829"(cytosol)|go:"GO:0006147"(guanine catabolic process)|go:"GO:0006161"(deoxyguanosine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008892"(guanine deaminase activity)|go:"GO:0019239"(deaminase activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0046055"(dGMP catabolic process)|go:"GO:0046098"(guanine metabolic process)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR014311(Guanine deaminase)|interpro:IPR032466|mint:Q9R111|reactome:R-MMU-74259|go:"GO:0046038"(GMP catabolic process)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:4GljtxkNduzgstV1OX/vkPJ/Qvg10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q8K183	intact:EBI-2696342	intact:EBI-1634920|uniprotkb:Q3TM83|uniprotkb:Q8BJQ5|ensembl:ENSMUSP00000038540	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pdxk_mouse(display_long)|uniprotkb:Pdxk(gene name)|psi-mi:Pdxk(display_short)|uniprotkb:Pkh(gene name synonym)|uniprotkb:Pyridoxine kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_742146.1|ensembl:ENSMUSG00000032788(gene)|ensembl:ENSMUST00000041616(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008478"(pyridoxal kinase activity)|go:"GO:0009443"(pyridoxal 5'-phosphate salvage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042823"(pyridoxal phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070280"(pyridoxal binding)|interpro:IPR004625("Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase")|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR029056|mint:Q8K183|rcsb pdb:6YK0|rcsb pdb:6YK1|reactome:R-MMU-6798695|reactome:R-MMU-964975	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:z+mCly2nHtdLZ6dlMOMpWgUi+1s10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P61922	intact:EBI-2696342	intact:EBI-2735742|uniprotkb:Q8BZA3|ensembl:ENSMUSP00000063548	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gabt_mouse(display_long)|uniprotkb:Abat(gene name)|psi-mi:Abat(display_short)|uniprotkb:Gabat(gene name synonym)|uniprotkb:Gamma-amino-N-butyrate transaminase(gene name synonym)|uniprotkb:GABA aminotransferase(gene name synonym)|uniprotkb:L-AIBAT(gene name synonym)|uniprotkb:"(S)-3-amino-2-methylpropionate transaminase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001164449.1|refseq:NP_766549.2|ensembl:ENSMUSG00000057880(gene)|ensembl:ENSMUST00000065987(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003867"(4-aminobutyrate transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007568"(aging)|go:"GO:0007620"(copulation)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0010039"(response to iron ion)|go:"GO:0014053"(negative regulation of gamma-aminobutyric acid secretion)|go:"GO:0021549"(cerebellum development)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031652"(positive regulation of heat generation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032144"(4-aminobutyrate transaminase complex)|go:"GO:0032145"(succinate-semialdehyde dehydrogenase binding)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0034386"("4-aminobutyrate:2-oxoglutarate transaminase activity")|go:"GO:0035094"(response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045471"(response to ethanol)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047298"("(S)-3-amino-2-methylpropionate transaminase activity")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:1902722"(positive regulation of prolactin secretion)|go:"GO:1904450"(positive regulation of aspartate secretion)|interpro:IPR004631(4-aminobutyrate aminotransferase, eukaryotic)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P61922|reactome:R-MMU-916853	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:/NUFp+gGU2QqCUc9KQbLdUwnWDA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q61171	intact:EBI-2696342	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P05202	intact:EBI-2696342	intact:EBI-444923|uniprotkb:Q3TIP6|uniprotkb:Q3UD91|uniprotkb:Q5HZH5|uniprotkb:O09188|ensembl:ENSMUSP00000034097	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:aatm_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)|uniprotkb:Got2(gene name)|psi-mi:Got2(display_short)|uniprotkb:Got-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034455.1|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0045471"(response to ethanol)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05202|rcsb pdb:3HLM|rcsb pdb:3PD6|rcsb pdb:3PDB|reactome:R-MMU-389661|reactome:R-MMU-8963693|reactome:R-MMU-8964539|reactome:R-MMU-70263|ensembl:ENSMUST00000034097(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|ensembl:ENSMUSG00000031672(gene)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:derWMXIiDl1XkaQdJ48VFA7HMzM10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9D7G0	intact:EBI-2696342	intact:EBI-773696|uniprotkb:Q76MX9|ensembl:ENSMUSP00000033809	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:prps1_mouse(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:Prps1(gene name)|psi-mi:Prps1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_067438.1|ensembl:ENSMUSG00000031432(gene)|ensembl:ENSMUST00000033809(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0016301"(kinase activity)|go:"GO:0019003"(GDP binding)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043531"(ADP binding)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|mint:Q9D7G0|reactome:R-MMU-73843	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:+Hih2M7JLTsjEglauBlPj182h9M10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P09671	intact:EBI-2696342	intact:EBI-1635071|uniprotkb:Q8VEM5|uniprotkb:Q64670|ensembl:ENSMUSP00000007012	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:sodm_mouse(display_long)|uniprotkb:Sod2(gene name)|psi-mi:Sod2(display_short)|uniprotkb:Sod-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_038699.2|ensembl:ENSMUSG00000006818(gene)|ensembl:ENSMUST00000007012(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000303"(response to superoxide)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0003032"(detection of oxygen)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007507"(heart development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048666"(neuron development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048773"(erythrophore differentiation)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P09671|reactome:R-MMU-2151201|reactome:R-MMU-3299685	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:ElUPIiA1JSb5vbfqnibv3He227E10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P99029	intact:EBI-2696342	intact:EBI-2735704|uniprotkb:Q9QX45|uniprotkb:Q9QZ75|ensembl:ENSMUSP00000025904	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:prdx5_mouse(display_long)|uniprotkb:Prdx5(gene name)|psi-mi:Prdx5(display_short)|uniprotkb:Prdx6(gene name synonym)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 2D-0014IV(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036151.1|ensembl:ENSMUSG00000024953(gene)|ensembl:ENSMUST00000025904(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR036249|interpro:IPR037944|mint:P99029|reactome:R-MMU-3299685|reactome:R-MMU-5628897|interpro:IPR013766(Thioredoxin domain)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:uWS2EcAdupLmsVsQ6h1AV+vRffs10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P16330	intact:EBI-2696342	intact:EBI-772515|uniprotkb:Q61424|uniprotkb:Q8C7C9|uniprotkb:Q91V42|uniprotkb:Q923F3|ensembl:ENSMUSP00000099409	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:cn37_mouse(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001139790.1|refseq:NP_034053.2|refseq:XP_017169734.1|ensembl:ENSMUSG00000006782(gene)|ensembl:ENSMUST00000103120(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P16330|rcsb pdb:2XMI|rcsb pdb:2Y1P|rcsb pdb:2Y3X|rcsb pdb:2YDB|rcsb pdb:2YDC|rcsb pdb:2YDD|rcsb pdb:2YOZ|rcsb pdb:2YP0|rcsb pdb:2YPC|rcsb pdb:2YPE|rcsb pdb:2YPH|rcsb pdb:2YQ9|rcsb pdb:3ZBR|rcsb pdb:3ZBS|rcsb pdb:3ZBZ|rcsb pdb:4WBI|rcsb pdb:4WBL|rcsb pdb:4WC9|rcsb pdb:4WCA|rcsb pdb:4WCB|rcsb pdb:4WCC|rcsb pdb:4WDA|rcsb pdb:4WDB|rcsb pdb:4WDD|rcsb pdb:4WDE|rcsb pdb:4WDF|rcsb pdb:4WDG|rcsb pdb:4WDH|rcsb pdb:4WEX|rcsb pdb:4WFR|rcsb pdb:5AE0	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:z0XniuUAwQzaZTvQmEmctKYNw9810090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P68254	intact:EBI-2696342	intact:EBI-400675|uniprotkb:P35216|uniprotkb:Q3TW69|uniprotkb:Q3UJN5|uniprotkb:Q5SP76|uniprotkb:Q5U423|uniprotkb:Q66JR6|ensembl:ENSMUSP00000100067|ensembl:ENSMUSP00000123605	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433t_mouse(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035869.1|ensembl:ENSMUSG00000076432(gene)|ensembl:ENSMUST00000103002(transcript)|ensembl:ENSMUST00000135088(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68254|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9614399	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q76MZ3	intact:EBI-2696342	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P63017	intact:EBI-2696342	intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P63101	intact:EBI-2696342	intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P68510	intact:EBI-2696342	intact:EBI-444641|uniprotkb:P11576|uniprotkb:P70198|uniprotkb:Q3TGZ9|ensembl:ENSMUSP00000019109	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433f_mouse(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035868.1|ensembl:ENSMUSG00000018965(gene)|ensembl:ENSMUST00000019109(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68510|rcsb pdb:5YQG|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P61982	intact:EBI-2696342	intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9CQV8	intact:EBI-2696342	intact:EBI-771608|uniprotkb:O70455|uniprotkb:Q3TY33|uniprotkb:Q3UAN6|ensembl:ENSMUSP00000018470	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:1433b_mouse(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_061223.2|refseq:XP_006499972.1|reactome:R-MMU-111447|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-170968|reactome:R-MMU-2028269|reactome:R-MMU-392517|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-75035|reactome:R-MMU-9614399|ensembl:ENSMUSG00000018326(gene)|ensembl:ENSMUST00000018470(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:4GNT|rcsb pdb:5F74|rcsb pdb:5WFU|rcsb pdb:5WFX	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:g94luGOxfq+Jbi0ztZ7gbAkp+2A10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P38647	intact:EBI-2696342	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P68040	intact:EBI-2696342	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9CXY6	intact:EBI-2696342	intact:EBI-2312782|uniprotkb:Q3U083|uniprotkb:Q5RKG0|uniprotkb:Q8CCY9|uniprotkb:Q99KS3|ensembl:ENSMUSP00000001042	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ilf2_mouse(display_long)|uniprotkb:Ilf2(gene name)|psi-mi:Ilf2(display_short)|uniprotkb:Nf45(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_080650.1|ensembl:ENSMUSG00000001016(gene)|ensembl:ENSMUST00000001042(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q9CXY6|rcsb pdb:4AT7|rcsb pdb:4AT8|rcsb pdb:4AT9|rcsb pdb:4ATB|reactome:R-MMU-6798695	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:HwUDuY6Ev7csoTThxZCW8nJT88o10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q99020	intact:EBI-2696342	intact:EBI-299641|ensembl:ENSMUSP00000074238|uniprotkb:Q8BPE0	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:roaa_mouse(display_long)|uniprotkb:Hnrnpab(gene name)|psi-mi:Hnrnpab(display_short)|uniprotkb:Cbf-a(gene name synonym)|uniprotkb:Cgbfa(gene name synonym)|uniprotkb:Hnrpab(gene name synonym)|uniprotkb:CArG-binding factor-A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000020358(gene)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|ensembl:ENSMUST00000074669(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|mint:Q99020|refseq:NP_034578.1|dip:DIP-31415N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:ltjLRkaO2WQfLDwCtMB3T0HGqdM10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P29341	intact:EBI-2696342	intact:EBI-773902|uniprotkb:Q99L36|ensembl:ENSMUSP00000001809	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pabp1_mouse(display_long)|uniprotkb:Pabpc1(gene name)|psi-mi:Pabpc1(display_short)|uniprotkb:Pabp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	dip:DIP-32127N|refseq:NP_032800.2|refseq:XP_011243641.1|ensembl:ENSMUSG00000022283(gene)|ensembl:ENSMUST00000001809(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045202"(synapse)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P29341|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-975956|reactome:R-MMU-975957	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:jvlQW6kphF2tkZwK72DtAXDPHvs10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q8R081	intact:EBI-2696342	intact:EBI-647483|uniprotkb:O54789|uniprotkb:Q8K0S7|uniprotkb:Q499X2|ensembl:ENSMUSP00000049407|ensembl:ENSMUSP00000133728	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrpl_mouse(display_long)|uniprotkb:Hnrpl(gene name synonym)|uniprotkb:Hnrnpl(gene name)|psi-mi:Hnrnpl(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_796275.3|refseq:XP_006539621.1|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:Q8R081|rcsb pdb:3S01|rcsb pdb:3TYT|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:1990715"(mRNA CDS binding)|ensembl:ENSMUSG00000015165(gene)|ensembl:ENSMUST00000038572(transcript)|ensembl:ENSMUST00000174548(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045120"(pronucleus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:1902416"(positive regulation of mRNA binding)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:BApt4fekoyJ285Ve13kxstcLbV010090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P56959	intact:EBI-2696342	intact:EBI-400452|ensembl:ENSMUSP00000101858	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:fus_mouse(display_long)|uniprotkb:Fus(gene name)|psi-mi:Fus(display_short)|uniprotkb:Protein pigpen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_631888.1|ensembl:ENSMUSG00000030795(gene)|ensembl:ENSMUST00000106251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P56959|reactome:R-MMU-72163	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:Vwv/0vlM50l49XaUOHCtEWt/b2A10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q6ZQ38	intact:EBI-2696342	intact:EBI-597255|uniprotkb:Q6PFR0|uniprotkb:Q9CV45|ensembl:ENSMUSP00000020315	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:cand1_mouse(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:Cand1(gene name)|psi-mi:Cand1(display_short)|uniprotkb:D10Ertd516e(gene name synonym)|uniprotkb:Kiaa0829(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_082270.1|ensembl:ENSMUSG00000020114(gene)|ensembl:ENSMUST00000020315(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:Q6ZQ38|reactome:R-MMU-6798695|reactome:R-MMU-8951664|reactome:R-MMU-917937	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:E6bJujLfT/V3C8Iyk0hUD1m4gT010090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P42669	intact:EBI-2696342	intact:EBI-773823|ensembl:ENSMUSP00000059404	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pura_mouse(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033015.1|refseq:XP_006525787.1|refseq:XP_011245162.1|ensembl:ENSMUSG00000043991(gene)|ensembl:ENSMUST00000051301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:P42669	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:3LVZ5qdZYeJyeUVPhy3cozxROWs10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P61979	intact:EBI-2696342	intact:EBI-299907|ensembl:ENSMUSP00000039269|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q8BGQ8|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrpk_mouse(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUST00000043269(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000021546(gene)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61979|reactome:R-MMU-4570464|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|refseq:NP_001288269.1|refseq:NP_001288270.1|refseq:NP_001288272.1|refseq:NP_001288273.1|refseq:NP_001288274.1|refseq:XP_017170884.1|refseq:XP_017170885.1|refseq:NP_079555.1|refseq:XP_006517166.1|refseq:XP_006517167.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q7TMK9	intact:EBI-2696342	intact:EBI-2735641|uniprotkb:O88991|uniprotkb:Q2YDV8|uniprotkb:Q68ED6|uniprotkb:Q80YV6|uniprotkb:Q8BGP1|uniprotkb:Q8C5K6|uniprotkb:Q8CGC2|uniprotkb:Q91ZR0|uniprotkb:Q99KU9|uniprotkb:Q9QYF4|ensembl:ENSMUSP00000133649	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:hnrpq_mouse(display_long)|uniprotkb:Syncrip(gene name)|psi-mi:Syncrip(display_short)|uniprotkb:Hnrpq(gene name synonym)|uniprotkb:Nsap1(gene name synonym)|uniprotkb:Nsap1l(gene name synonym)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:pp68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001271257.1|refseq:NP_062640.2|refseq:NP_062770.1|refseq:NP_001298042.1|ensembl:ENSMUSG00000032423(gene)|ensembl:ENSMUST00000173801(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:Q7TMK9	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:Ljuz8koebOL7L9jFBaevQYHinzw10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P49312	intact:EBI-2696342	intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:O08553	intact:EBI-2696342	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q01853	intact:EBI-2696342	intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q8BG05	intact:EBI-2696342	intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P05213	intact:EBI-2696342	intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P03995	intact:EBI-2696342	intact:EBI-1634365|uniprotkb:Q80VX6|uniprotkb:Q925K2|uniprotkb:Q925K3|uniprotkb:A1E2H7|uniprotkb:A2AH87|uniprotkb:Q09J71|uniprotkb:Q3USS4|uniprotkb:Q496R4|uniprotkb:Q496S3|uniprotkb:Q7TQ30|ensembl:ENSMUSP00000064691|uniprotkb:B2RTI7	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gfap_mouse(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001124492.1|refseq:NP_034407.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|ensembl:ENSMUSG00000020932(gene)|ensembl:ENSMUST00000067444(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|dip:DIP-1084N|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P03995	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:y7+aINs6vTxOHokkQCqgejlZfh010090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P84091	intact:EBI-2696342	intact:EBI-297703|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSMUSP00000007216	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ap2m1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Clapm1(gene name synonym)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033809.1|ensembl:ENSMUSG00000022841(gene)|ensembl:ENSMUST00000007216(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84091|rcsb pdb:6OWO|rcsb pdb:6OWT|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q68FD5	intact:EBI-2696342	intact:EBI-769168|ensembl:ENSMUSP00000099475	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:clh1_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001003908.1|dip:DIP-31947N|ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000103186(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q68FD5|rcsb pdb:5ODS|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0032051"(clathrin light chain binding)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:iHg/TOG2rWePqtsEmuc/szn/chI10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P50396	intact:EBI-2696342	intact:EBI-1634930|uniprotkb:A2AMA8|uniprotkb:Q3TBI9|uniprotkb:Q8VHM3|uniprotkb:Q91Y71|uniprotkb:Q91Z41|uniprotkb:Q96CX5|ensembl:ENSMUSP00000015435	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:gdia_mouse(display_long)|uniprotkb:Gdi1(gene name)|psi-mi:Gdi1(display_short)|uniprotkb:Rabgdia(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000015291(gene)|ensembl:ENSMUST00000015435(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|refseq:NP_034403.1|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50396|reactome:R-MMU-8876198|go:"GO:0043209"(myelin sheath)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:PedrlfCE1ZCgXPtL9PZmNfOoxdo10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q62261	intact:EBI-2696342	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P39053	intact:EBI-2696342	intact:EBI-397785|ensembl:ENSMUSP00000122679|uniprotkb:A2AN50|uniprotkb:A2AN51|uniprotkb:A2AN54|uniprotkb:A2AN55|uniprotkb:Q3UNM1|uniprotkb:Q5DTN7|uniprotkb:Q61358|uniprotkb:Q61359|uniprotkb:Q61360|uniprotkb:Q6PDM5|uniprotkb:Q8JZZ4|uniprotkb:Q9CSY7|uniprotkb:Q9QXX1	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dyn1_mouse(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:Kiaa4093(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034195.2|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P39053|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-437239|reactome:R-MMU-8856828|ensembl:ENSMUSG00000026825(gene)|ensembl:ENSMUST00000139624(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|refseq:NP_001288666.1|refseq:XP_006497721.2|refseq:XP_006497722.2|refseq:XP_006497723.2|refseq:XP_006497724.2|refseq:XP_006497718.2|refseq:XP_017170817.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:wtPz3gwyxU6tAgh5091LQpt099I10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9DBG3	intact:EBI-2696342	intact:EBI-775229|uniprotkb:Q80XJ4|ensembl:ENSMUSP00000070714	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ap2b1_mouse(display_long)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001030931.1|refseq:NP_082191.1|refseq:XP_006534321.1|refseq:XP_017170261.1|dip:DIP-32161N|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q9DBG3|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:O08599	intact:EBI-2696342	intact:EBI-445322|uniprotkb:A2ARS2|uniprotkb:A2ARS3|uniprotkb:A2ARS4|uniprotkb:Q5WAC6|uniprotkb:Q8VD51|ensembl:ENSMUSP00000052440	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:stxb1_mouse(display_long)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001107041.1|refseq:NP_033321.2|interpro:IPR043127|interpro:IPR043154|mint:O08599|go:"GO:0098794"(postsynapse)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|reactome:R-MMU-181429|reactome:R-MMU-181430|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-888590|ensembl:ENSMUSG00000026797(gene)|ensembl:ENSMUST00000050000(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|dip:DIP-31951N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P16546	intact:EBI-2696342	intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P17426	intact:EBI-2696342	intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P46096	intact:EBI-2696342	intact:EBI-445340|ensembl:ENSMUSP00000063293|ensembl:ENSMUSP00000100912	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:syt1_mouse(display_long)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001239271.1|refseq:NP_033332.1|refseq:XP_006513509.1|refseq:XP_006513510.1|refseq:XP_006513511.1|refseq:NP_001239270.1|ensembl:ENSMUSG00000035864(gene)|ensembl:ENSMUST00000064054(transcript)|ensembl:ENSMUST00000105276(transcript)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0000149"(SNARE binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|refseq:XP_017169355.1|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P46096|rcsb pdb:5T0R|rcsb pdb:5T0S|rcsb pdb:5VFE|rcsb pdb:5VFF|rcsb pdb:5VFG|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-888590|dip:DIP-31322N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:CxQGrKu3l0pEzQ3aJZBJ/GZMyEA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P63260	intact:EBI-2696342	intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q8CI94	intact:EBI-2696342	intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P05063	intact:EBI-2696342	intact:EBI-444845|uniprotkb:Q64011|uniprotkb:Q8CA91|uniprotkb:Q99K96|uniprotkb:Q9DBA4|uniprotkb:Q9JK32|ensembl:ENSMUSP00000017534|ensembl:ENSMUSP00000099536	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:aldoc_mouse(display_long)|uniprotkb:Brain-type aldolase(gene name synonym)|uniprotkb:Aldolase 3(gene name synonym)|uniprotkb:Zebrin II(gene name synonym)|uniprotkb:Scrapie-responsive protein 2(gene name synonym)|uniprotkb:Aldoc(gene name)|psi-mi:Aldoc(display_short)|uniprotkb:Aldo3(gene name synonym)|uniprotkb:Scrg2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033787.2|go:"GO:0030424"(axon)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUST00000017534(transcript)|ensembl:ENSMUST00000102478(transcript)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|mint:P05063|reactome:R-MMU-6798695|reactome:R-MMU-70171|go:"GO:0005829"(cytosol)|reactome:R-MMU-70263|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|refseq:NP_001290352.1|ensembl:ENSMUSG00000017390(gene)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:MFpDc0rZbQY47QNygDUe2T6XIYU10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P17182	intact:EBI-2696342	intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q60597	intact:EBI-2696342	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P16858	intact:EBI-2696342	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P06151	intact:EBI-2696342	intact:EBI-444940|ensembl:ENSMUSP00000036386|ensembl:ENSMUSP00000103267	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ldha_mouse(display_long)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh-1(gene name synonym)|uniprotkb:Ldh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034829.1|ensembl:ENSMUSG00000063229(gene)|ensembl:ENSMUST00000005051(transcript)|ensembl:ENSMUST00000048209(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019661"(glucose catabolic process to lactate via pyruvate)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P06151|reactome:R-MMU-70268	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:IErFuOIWq53/XyIxWgUyVi76VnM10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q05920	intact:EBI-2696342	intact:EBI-773565	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pyc_mouse(display_long)|uniprotkb:Pyruvic carboxylase(gene name synonym)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:Pcx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)|mint:Q05920|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|reactome:R-MMU-196780|reactome:R-MMU-70263	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:lsSatV0UMI9POKETZcn4gD/gp1Q10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P35486	intact:EBI-2696342	intact:EBI-773613|ensembl:ENSMUSP00000033662	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:odpa_mouse(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)|uniprotkb:Pdha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_032836.1|ensembl:ENSMUSG00000031299(gene)|ensembl:ENSMUST00000033662(transcript)|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0043209"(myelin sheath)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|mint:P35486|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:QIfCMikb5tVYwefUZs3+5ut/nbY10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P16125	intact:EBI-2696342	intact:EBI-444932|uniprotkb:Q545Y4|ensembl:ENSMUSP00000032373|ensembl:ENSMUSP00000159362	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:ldhb_mouse(display_long)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Ldhb(gene name)|psi-mi:Ldhb(display_short)|uniprotkb:Ldh-2(gene name synonym)|uniprotkb:Ldh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_032518.1|refseq:NP_001303251.1|ensembl:ENSMUSG00000030246(gene)|ensembl:ENSMUST00000032373(transcript)|ensembl:ENSMUST00000239397(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0051287"(NAD binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P16125|reactome:R-MMU-70268|interpro:IPR001557(L-lactate/malate dehydrogenase)|refseq:NP_001289694.1	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:jN0wT7b/jHBnWCfV48irZYeGxa410090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P62814	intact:EBI-2696342	intact:EBI-772655|uniprotkb:Q3U9Z0|uniprotkb:Q3UAW7|uniprotkb:Q3TG74|uniprotkb:Q3U7C8|uniprotkb:Q3TL62|uniprotkb:Q3TVK6|uniprotkb:Q3TWR0|uniprotkb:Q3U791|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSMUSP00000006435	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:vatb2_mouse(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031535.2|ensembl:ENSMUSG00000006273(gene)|ensembl:ENSMUST00000006435(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62814|reactome:R-MMU-1222556|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:O08749	intact:EBI-2696342	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P30275	intact:EBI-2696342	intact:EBI-773103|ensembl:ENSMUSP00000000317|ensembl:ENSMUSP00000077349	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:kcru_mouse(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:Ckmt1(gene name)|psi-mi:Ckmt1(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034027.1|refseq:XP_006498718.1|refseq:XP_006498719.1|dip:DIP-32284N|ensembl:ENSMUSG00000000308(gene)|ensembl:ENSMUST00000000317(transcript)|ensembl:ENSMUST00000078222(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044289"(mitochondrial inner-outer membrane contact site)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P30275|reactome:R-MMU-71288	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:H9YUmEsZlopypKgZnoMJbIqI6lw10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P97807	intact:EBI-2696342	intact:EBI-1634334|uniprotkb:Q99JL0|uniprotkb:Q9DCX0|intact:EBI-2257633|uniprotkb:Q3UIA9|ensembl:ENSMUSP00000027810	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:fumh_mouse(display_long)|uniprotkb:Fh(gene name)|psi-mi:Fh(display_short)|uniprotkb:Fh1(gene name synonym)|uniprotkb:EF-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034339.2|ensembl:ENSMUSG00000026526(gene)|ensembl:ENSMUST00000027810(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000821"(regulation of arginine metabolic process)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|mint:P97807|reactome:R-MMU-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:iF/OldWMCxdHfdZo+JtXmx8PbFQ10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P17751	intact:EBI-2696342	intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q04447	intact:EBI-2696342	intact:EBI-1634233|uniprotkb:Q3KQP4|uniprotkb:Q3TKI3|uniprotkb:Q3U5P5|uniprotkb:Q3UF71|uniprotkb:Q9CXK6|ensembl:ENSMUSP00000001304	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:kcrb_mouse(display_long)|uniprotkb:Ckb(gene name)|psi-mi:Ckb(display_short)|uniprotkb:Ckbb(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:B-CK(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_067248.1|ensembl:ENSMUSG00000001270(gene)|ensembl:ENSMUST00000001304(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q04447|reactome:R-MMU-71288|reactome:R-MMU-9696264	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:7r2Owq3p9g124vCs/sG4m8aScuU10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q9D051	intact:EBI-2696342	intact:EBI-773622|uniprotkb:Q3TL86|uniprotkb:Q505N8|uniprotkb:Q99LW9|ensembl:ENSMUSP00000022268	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:odpb_mouse(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_077183.1|ensembl:ENSMUSG00000021748(gene)|ensembl:ENSMUST00000022268(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:Q9D051|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:FPts4odLhVgLVf3gEYdc9N5Wuak10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P17183	intact:EBI-2696342	intact:EBI-1634308|ensembl:ENSMUSP00000004378	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:enog_mouse(display_long)|uniprotkb:Eno2(gene name)|psi-mi:Eno2(display_short)|uniprotkb:Eno-2(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Neural enolase(gene name synonym)|uniprotkb:Neuron-specific enolase(gene name synonym)|uniprotkb:Enolase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_038537.1|refseq:NP_001289571.1|refseq:XP_006505566.1|refseq:XP_006505567.1|ensembl:ENSMUSG00000004267(gene)|ensembl:ENSMUST00000004378(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0097060"(synaptic membrane)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17183|reactome:R-MMU-70171|reactome:R-MMU-70263	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:bEXS2/h1idLiCLtUPFHMwtCMV5I10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:Q99KI0	intact:EBI-2696342	intact:EBI-444886|uniprotkb:Q3UDK9|uniprotkb:Q3ULG9|uniprotkb:Q3UNH7|uniprotkb:Q505P4|ensembl:ENSMUSP00000023116	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:acon_mouse(display_long)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_542364.1|ensembl:ENSMUSG00000022477(gene)|ensembl:ENSMUST00000023116(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0043209"(myelin sheath)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99KI0|reactome:R-MMU-71403|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:0NOVcGhBwl4qmtnlhX9jcsQMdSo10090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P08249	intact:EBI-2696342	intact:EBI-773487|uniprotkb:Q0QF44|uniprotkb:Q8CF79|uniprotkb:Q8R1P0|ensembl:ENSMUSP00000019323	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:mdhm_mouse(display_long)|uniprotkb:Mdh2(gene name)|psi-mi:Mdh2(display_short)|uniprotkb:Mor1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696883|imex:IM-20484-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_032643.2|ensembl:ENSMUSG00000019179(gene)|ensembl:ENSMUST00000019323(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0016615"(malate dehydrogenase activity)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P08249|reactome:R-MMU-70263|reactome:R-MMU-71403	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 3.|comment:Identification of mouse brain isatin-binding proteins|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2010/06/08	2020/10/21	-	rogid:KG/ilme6qKXuXKp3BqXC5kQ0dM410090	intact-crc:74A83CD45F336FB3	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:59639"	uniprotkb:P46406	intact:EBI-2696342	intact:EBI-2750726|uniprotkb:Q4AC92	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:g3p_rabit(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2750723|imex:IM-20484-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001075722.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097452"(GAIT complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|rcsb pdb:1J0X|dip:DIP-6005N|mint:P46406	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:KAUZGWUD9KH101k31hsREciDO+49986	intact-crc:47EE43293559419E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59593"	uniprotkb:P00563	intact:EBI-2750788	intact:EBI-2750756	psi-mi:5-aminoisatin(display_short)|psi-mi:"CHEBI:59593"(display_long)	psi-mi:kcrm_rabit(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2750749|imex:IM-20484-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:NP_001075708.1|interpro:IPR000749("ATP:guanido phosphotransferase")|rcsb pdb:1U6R|rcsb pdb:2CRK|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009408"(response to heat)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR036802|mint:P00563	-	-	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:m2yat412XZ2tXBXs3yBA8EJjhQs9986	intact-crc:D60A2288CD25F988	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59639"	uniprotkb:Q06830	intact:EBI-2696342	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2750770|imex:IM-20484-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	intact-crc:D3708643F691AB51	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59639"	uniprotkb:P00489	intact:EBI-2696342	intact:EBI-1373425	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:pygm_rabit(display_long)|uniprotkb:Myophosphorylase(gene name synonym)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2750776|imex:IM-20484-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001075653.1|dip:DIP-38240N|mint:P00489|go:"GO:0000166"(nucleotide binding)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1A8I|rcsb pdb:1ABB|rcsb pdb:1AXR|rcsb pdb:1B4D|rcsb pdb:1BX3|rcsb pdb:1C50|rcsb pdb:1C8K|rcsb pdb:1C8L|rcsb pdb:1E1Y|rcsb pdb:1FS4|rcsb pdb:1FTQ|rcsb pdb:1FTW|rcsb pdb:1FTY|rcsb pdb:1FU4|rcsb pdb:1FU7|rcsb pdb:1FU8|rcsb pdb:1GFZ|rcsb pdb:1GG8|rcsb pdb:1GGN|rcsb pdb:1GPA|rcsb pdb:1GPB|rcsb pdb:1GPY|rcsb pdb:1H5U|rcsb pdb:1HLF|rcsb pdb:1K06|rcsb pdb:1K08|rcsb pdb:1KTI|rcsb pdb:1LWN|rcsb pdb:1LWO|rcsb pdb:1NOI|rcsb pdb:1NOJ|rcsb pdb:1NOK|rcsb pdb:1P29|rcsb pdb:1P2B|rcsb pdb:1P2D|rcsb pdb:1P2G|rcsb pdb:1P4G|rcsb pdb:1P4H|rcsb pdb:1P4J|rcsb pdb:1PYG|rcsb pdb:1UZU|rcsb pdb:1WUT|rcsb pdb:1WUY|rcsb pdb:1WV0|rcsb pdb:1WV1|rcsb pdb:1WW2|rcsb pdb:1WW3|rcsb pdb:1XC7|rcsb pdb:1XKX|rcsb pdb:1XL0|rcsb pdb:1XL1|rcsb pdb:1Z62|rcsb pdb:1Z6P|rcsb pdb:1Z6Q|rcsb pdb:2AMV|rcsb pdb:2F3P|rcsb pdb:2F3Q|rcsb pdb:2F3S|rcsb pdb:2F3U|rcsb pdb:2FET|rcsb pdb:2FF5|rcsb pdb:2FFR|rcsb pdb:2G9Q|rcsb pdb:2G9R|rcsb pdb:2G9U|rcsb pdb:2G9V|rcsb pdb:2GJ4|rcsb pdb:2GM9|rcsb pdb:2GPA|rcsb pdb:2GPB|rcsb pdb:2GPN|rcsb pdb:2IEG|rcsb pdb:2IEI|rcsb pdb:2OFF|rcsb pdb:2PRI|rcsb pdb:2PRJ|rcsb pdb:2PYD|rcsb pdb:2PYI|rcsb pdb:2QLM|rcsb pdb:2QLN|rcsb pdb:2QN1|rcsb pdb:2QN2|rcsb pdb:2QN3|rcsb pdb:2QN7|rcsb pdb:2QN8|rcsb pdb:2QN9|rcsb pdb:2QNB|rcsb pdb:2QRG|rcsb pdb:2QRH|rcsb pdb:2QRM|rcsb pdb:2QRP|rcsb pdb:2QRQ|rcsb pdb:2SKC|rcsb pdb:2SKD|rcsb pdb:2SKE|rcsb pdb:3AMV|rcsb pdb:3BCR|rcsb pdb:3BCS|rcsb pdb:3BCU|rcsb pdb:3BD6|rcsb pdb:3BD7|rcsb pdb:3BD8|rcsb pdb:3BDA|rcsb pdb:3CUT|rcsb pdb:3CUU|rcsb pdb:3CUV|rcsb pdb:3CUW|rcsb pdb:3E3L|rcsb pdb:3E3N|rcsb pdb:3E3O|rcsb pdb:3EBO|rcsb pdb:3EBP|rcsb pdb:3G2H|rcsb pdb:3G2I|rcsb pdb:3G2J|rcsb pdb:3G2K|rcsb pdb:3G2L|rcsb pdb:3G2N|rcsb pdb:3GPB|rcsb pdb:3L79|rcsb pdb:3L7A|rcsb pdb:3L7B|rcsb pdb:3L7C|rcsb pdb:3L7D|rcsb pdb:3MQF|rcsb pdb:3MRT|rcsb pdb:3MRV|rcsb pdb:3MRX|rcsb pdb:3MS2|rcsb pdb:3MS4|rcsb pdb:3MS7|rcsb pdb:3MSC|rcsb pdb:3MT7|rcsb pdb:3MT8|rcsb pdb:3MT9|rcsb pdb:3MTA|rcsb pdb:3MTB|rcsb pdb:3MTD|rcsb pdb:3NC4|rcsb pdb:3NP7|rcsb pdb:3NP9|rcsb pdb:3NPA|rcsb pdb:3S0J|rcsb pdb:3SYM|rcsb pdb:3SYR|rcsb pdb:3T3D|rcsb pdb:3T3E|rcsb pdb:3T3G|rcsb pdb:3T3H|rcsb pdb:3T3I|rcsb pdb:3ZCP|rcsb pdb:3ZCQ|rcsb pdb:3ZCR|rcsb pdb:3ZCS|rcsb pdb:3ZCT|rcsb pdb:3ZCU|rcsb pdb:3ZCV|rcsb pdb:4CTM|rcsb pdb:4CTN|rcsb pdb:4CTO|rcsb pdb:4EJ2|rcsb pdb:4EKE|rcsb pdb:4EKY|rcsb pdb:4EL0|rcsb pdb:4EL5|rcsb pdb:4GPB|rcsb pdb:4MHO|rcsb pdb:4MHS|rcsb pdb:4MI3|rcsb pdb:4MI6|rcsb pdb:4MI9|rcsb pdb:4MIC|rcsb pdb:4MRA|rcsb pdb:4YI3|rcsb pdb:4YI5|rcsb pdb:4YUA|rcsb pdb:4Z5X|rcsb pdb:5GPB|rcsb pdb:5JTT|rcsb pdb:5JTU|rcsb pdb:5LRC|rcsb pdb:5LRD|rcsb pdb:5LRE|rcsb pdb:5LRF|rcsb pdb:5MCB|rcsb pdb:5MEM|rcsb pdb:5O50|rcsb pdb:5O52|rcsb pdb:5O54|rcsb pdb:5O56|rcsb pdb:5OWY|rcsb pdb:5OWZ|rcsb pdb:5OX0|rcsb pdb:5OX1|rcsb pdb:5OX3|rcsb pdb:5OX4|rcsb pdb:6F3J|rcsb pdb:6F3L|rcsb pdb:6F3R|rcsb pdb:6F3S|rcsb pdb:6F3U|rcsb pdb:6GPB|rcsb pdb:6QA6|rcsb pdb:6QA7|rcsb pdb:6QA8|rcsb pdb:6R0H|rcsb pdb:6R0I|rcsb pdb:6S4H|rcsb pdb:6S4K|rcsb pdb:6S4O|rcsb pdb:6S4P|rcsb pdb:6S4R|rcsb pdb:6S51|rcsb pdb:6S52|rcsb pdb:6Y55|rcsb pdb:6Y5C|rcsb pdb:6Y5O|rcsb pdb:6YVE|rcsb pdb:7GPB|rcsb pdb:7O8E|rcsb pdb:8GPB|rcsb pdb:9GPB	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:2Qbs9Zc+YJkBsbK1/qeP9c3gjys9986	intact-crc:A383B4B0F55C5B1F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59593"	uniprotkb:P46406	intact:EBI-2750788	intact:EBI-2750726|uniprotkb:Q4AC92	psi-mi:5-aminoisatin(display_short)|psi-mi:"CHEBI:59593"(display_long)	psi-mi:g3p_rabit(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2774719|imex:IM-20484-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001075722.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097452"(GAIT complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|rcsb pdb:1J0X|dip:DIP-6005N|mint:P46406	-	-	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:KAUZGWUD9KH101k31hsREciDO+49986	intact-crc:89AE911D903FA53E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59639"	uniprotkb:P00563	intact:EBI-2696342	intact:EBI-2750756	psi-mi:5-nh2_caproyl-isatin(display_short)|psi-mi:"CHEBI:59639"(display_long)	psi-mi:kcrm_rabit(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2789903|imex:IM-20484-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:NP_001075708.1|interpro:IPR000749("ATP:guanido phosphotransferase")|rcsb pdb:1U6R|rcsb pdb:2CRK|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009408"(response to heat)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR036802|mint:P00563	-	comment:Isatin bearing a 6-aminohexanamido group at C-5.	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:m2yat412XZ2tXBXs3yBA8EJjhQs9986	intact-crc:184AF0BC68431D28	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59593"	uniprotkb:Q06830	intact:EBI-2750788	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:5-aminoisatin(display_short)|psi-mi:"CHEBI:59593"(display_long)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2793040|imex:IM-20484-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	intact-crc:3A5FA26D38D17965	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:59593"	uniprotkb:P00489	intact:EBI-2750788	intact:EBI-1373425	psi-mi:5-aminoisatin(display_short)|psi-mi:"CHEBI:59593"(display_long)	psi-mi:pygm_rabit(display_long)|uniprotkb:Myophosphorylase(gene name synonym)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Buneeva et al. (2010)	pubmed:19834914|imex:IM-20484	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2793047|imex:IM-20484-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001075653.1|dip:DIP-38240N|mint:P00489|go:"GO:0000166"(nucleotide binding)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1A8I|rcsb pdb:1ABB|rcsb pdb:1AXR|rcsb pdb:1B4D|rcsb pdb:1BX3|rcsb pdb:1C50|rcsb pdb:1C8K|rcsb pdb:1C8L|rcsb pdb:1E1Y|rcsb pdb:1FS4|rcsb pdb:1FTQ|rcsb pdb:1FTW|rcsb pdb:1FTY|rcsb pdb:1FU4|rcsb pdb:1FU7|rcsb pdb:1FU8|rcsb pdb:1GFZ|rcsb pdb:1GG8|rcsb pdb:1GGN|rcsb pdb:1GPA|rcsb pdb:1GPB|rcsb pdb:1GPY|rcsb pdb:1H5U|rcsb pdb:1HLF|rcsb pdb:1K06|rcsb pdb:1K08|rcsb pdb:1KTI|rcsb pdb:1LWN|rcsb pdb:1LWO|rcsb pdb:1NOI|rcsb pdb:1NOJ|rcsb pdb:1NOK|rcsb pdb:1P29|rcsb pdb:1P2B|rcsb pdb:1P2D|rcsb pdb:1P2G|rcsb pdb:1P4G|rcsb pdb:1P4H|rcsb pdb:1P4J|rcsb pdb:1PYG|rcsb pdb:1UZU|rcsb pdb:1WUT|rcsb pdb:1WUY|rcsb pdb:1WV0|rcsb pdb:1WV1|rcsb pdb:1WW2|rcsb pdb:1WW3|rcsb pdb:1XC7|rcsb pdb:1XKX|rcsb pdb:1XL0|rcsb pdb:1XL1|rcsb pdb:1Z62|rcsb pdb:1Z6P|rcsb pdb:1Z6Q|rcsb pdb:2AMV|rcsb pdb:2F3P|rcsb pdb:2F3Q|rcsb pdb:2F3S|rcsb pdb:2F3U|rcsb pdb:2FET|rcsb pdb:2FF5|rcsb pdb:2FFR|rcsb pdb:2G9Q|rcsb pdb:2G9R|rcsb pdb:2G9U|rcsb pdb:2G9V|rcsb pdb:2GJ4|rcsb pdb:2GM9|rcsb pdb:2GPA|rcsb pdb:2GPB|rcsb pdb:2GPN|rcsb pdb:2IEG|rcsb pdb:2IEI|rcsb pdb:2OFF|rcsb pdb:2PRI|rcsb pdb:2PRJ|rcsb pdb:2PYD|rcsb pdb:2PYI|rcsb pdb:2QLM|rcsb pdb:2QLN|rcsb pdb:2QN1|rcsb pdb:2QN2|rcsb pdb:2QN3|rcsb pdb:2QN7|rcsb pdb:2QN8|rcsb pdb:2QN9|rcsb pdb:2QNB|rcsb pdb:2QRG|rcsb pdb:2QRH|rcsb pdb:2QRM|rcsb pdb:2QRP|rcsb pdb:2QRQ|rcsb pdb:2SKC|rcsb pdb:2SKD|rcsb pdb:2SKE|rcsb pdb:3AMV|rcsb pdb:3BCR|rcsb pdb:3BCS|rcsb pdb:3BCU|rcsb pdb:3BD6|rcsb pdb:3BD7|rcsb pdb:3BD8|rcsb pdb:3BDA|rcsb pdb:3CUT|rcsb pdb:3CUU|rcsb pdb:3CUV|rcsb pdb:3CUW|rcsb pdb:3E3L|rcsb pdb:3E3N|rcsb pdb:3E3O|rcsb pdb:3EBO|rcsb pdb:3EBP|rcsb pdb:3G2H|rcsb pdb:3G2I|rcsb pdb:3G2J|rcsb pdb:3G2K|rcsb pdb:3G2L|rcsb pdb:3G2N|rcsb pdb:3GPB|rcsb pdb:3L79|rcsb pdb:3L7A|rcsb pdb:3L7B|rcsb pdb:3L7C|rcsb pdb:3L7D|rcsb pdb:3MQF|rcsb pdb:3MRT|rcsb pdb:3MRV|rcsb pdb:3MRX|rcsb pdb:3MS2|rcsb pdb:3MS4|rcsb pdb:3MS7|rcsb pdb:3MSC|rcsb pdb:3MT7|rcsb pdb:3MT8|rcsb pdb:3MT9|rcsb pdb:3MTA|rcsb pdb:3MTB|rcsb pdb:3MTD|rcsb pdb:3NC4|rcsb pdb:3NP7|rcsb pdb:3NP9|rcsb pdb:3NPA|rcsb pdb:3S0J|rcsb pdb:3SYM|rcsb pdb:3SYR|rcsb pdb:3T3D|rcsb pdb:3T3E|rcsb pdb:3T3G|rcsb pdb:3T3H|rcsb pdb:3T3I|rcsb pdb:3ZCP|rcsb pdb:3ZCQ|rcsb pdb:3ZCR|rcsb pdb:3ZCS|rcsb pdb:3ZCT|rcsb pdb:3ZCU|rcsb pdb:3ZCV|rcsb pdb:4CTM|rcsb pdb:4CTN|rcsb pdb:4CTO|rcsb pdb:4EJ2|rcsb pdb:4EKE|rcsb pdb:4EKY|rcsb pdb:4EL0|rcsb pdb:4EL5|rcsb pdb:4GPB|rcsb pdb:4MHO|rcsb pdb:4MHS|rcsb pdb:4MI3|rcsb pdb:4MI6|rcsb pdb:4MI9|rcsb pdb:4MIC|rcsb pdb:4MRA|rcsb pdb:4YI3|rcsb pdb:4YI5|rcsb pdb:4YUA|rcsb pdb:4Z5X|rcsb pdb:5GPB|rcsb pdb:5JTT|rcsb pdb:5JTU|rcsb pdb:5LRC|rcsb pdb:5LRD|rcsb pdb:5LRE|rcsb pdb:5LRF|rcsb pdb:5MCB|rcsb pdb:5MEM|rcsb pdb:5O50|rcsb pdb:5O52|rcsb pdb:5O54|rcsb pdb:5O56|rcsb pdb:5OWY|rcsb pdb:5OWZ|rcsb pdb:5OX0|rcsb pdb:5OX1|rcsb pdb:5OX3|rcsb pdb:5OX4|rcsb pdb:6F3J|rcsb pdb:6F3L|rcsb pdb:6F3R|rcsb pdb:6F3S|rcsb pdb:6F3U|rcsb pdb:6GPB|rcsb pdb:6QA6|rcsb pdb:6QA7|rcsb pdb:6QA8|rcsb pdb:6R0H|rcsb pdb:6R0I|rcsb pdb:6S4H|rcsb pdb:6S4K|rcsb pdb:6S4O|rcsb pdb:6S4P|rcsb pdb:6S4R|rcsb pdb:6S51|rcsb pdb:6S52|rcsb pdb:6Y55|rcsb pdb:6Y5C|rcsb pdb:6Y5O|rcsb pdb:6YVE|rcsb pdb:7GPB|rcsb pdb:7O8E|rcsb pdb:8GPB|rcsb pdb:9GPB	-	-	-	figure legend:Table 5.|comment:Comparison of the interaction of selected individual proteins not only with 5-aminocaproyl-isatin but also with 5-amino-isatin.|kinetic_conditions:pH=8.5, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/08	2014/10/16	-	rogid:2Qbs9Zc+YJkBsbK1/qeP9c3gjys9986	intact-crc:4CC4E4DFA4484CD8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)