#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P34042	uniprotkb:Q54QB1	intact:EBI-2905587|ensemblprotists:EAL64550|uniprotkb:Q54MU7	intact:EBI-2905550|ensemblprotists:EAL65439|uniprotkb:Q7M445	psi-mi:gpa4_dicdi(display_long)|uniprotkb:gpaD(gene name)|psi-mi:gpaD(display_short)|uniprotkb:DDB_G0285425(orf name)	psi-mi:erk2_dicdi(display_long)|uniprotkb:erkB(gene name)|psi-mi:erkB(display_short)|uniprotkb:dagC(gene name synonym)|uniprotkb:erk2(gene name synonym)|uniprotkb:Defective in aggregation protein C(gene name synonym)|uniprotkb:MAP kinase 2(gene name synonym)|uniprotkb:DDB_G0283903(orf name)	psi-mi:"MI:0096"(pull down)	Nguyen et al. (2009)	pubmed:19765570|imex:IM-20504	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2905583|imex:IM-20504-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblprotists:DDB_G0285425(gene)|ensemblprotists:EAL64550(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0043326"(chemotaxis to folate)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:1905301"(regulation of macropinocytosis)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-DDI-112043|reactome:R-DDI-170660|reactome:R-DDI-170670|reactome:R-DDI-202040|reactome:R-DDI-2485179|reactome:R-DDI-2514859|reactome:R-DDI-399997|reactome:R-DDI-4086398|reactome:R-DDI-416476|reactome:R-DDI-416482|reactome:R-DDI-418594|reactome:R-DDI-418597|reactome:R-DDI-434316|reactome:R-DDI-9013149|refseq:XP_638196.1|dictybase:DDB_G0285425	go:"GO:0140582"(adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway)|go:"GO:1903013"(response to differentiation-inducing factor 1)|go:"GO:1905301"(regulation of macropinocytosis)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_638833.1|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016301"(kinase activity)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043326"(chemotaxis to folate)|ensemblprotists:DDB_G0283903(gene)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0044671"(sorocarp spore cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072718"(response to cisplatin)|go:"GO:0106310"(protein serine kinase activity)|ensemblprotists:EAL65439(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0106311"|dictybase:DDB_G0283903	-	-	-	figure legend:Fig. 2D, Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	-	2010/08/11	2014/10/16	rogid:bxeaLhUqcblrPbTcXKq+IoSoIoU44689	rogid:JRaXTXUKigMuEZjRfRWa7oH6OMA44689	intact-crc:2B10F7CCDB9E0F93|rigid:Qu3xH6xHMosS1foJyk/6es0i3ho	false	mutation decreasing interaction:107-108|mutation decreasing interaction:200-200|mutation disrupting interaction:107-108,200-200|myc tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P34042	uniprotkb:Q54QB1	intact:EBI-2905587|ensemblprotists:EAL64550|uniprotkb:Q54MU7	intact:EBI-2905550|ensemblprotists:EAL65439|uniprotkb:Q7M445	psi-mi:gpa4_dicdi(display_long)|uniprotkb:gpaD(gene name)|psi-mi:gpaD(display_short)|uniprotkb:DDB_G0285425(orf name)	psi-mi:erk2_dicdi(display_long)|uniprotkb:erkB(gene name)|psi-mi:erkB(display_short)|uniprotkb:dagC(gene name synonym)|uniprotkb:erk2(gene name synonym)|uniprotkb:Defective in aggregation protein C(gene name synonym)|uniprotkb:MAP kinase 2(gene name synonym)|uniprotkb:DDB_G0283903(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nguyen et al. (2009)	pubmed:19765570|imex:IM-20504	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2905615|imex:IM-20504-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblprotists:DDB_G0285425(gene)|ensemblprotists:EAL64550(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0043326"(chemotaxis to folate)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:1905301"(regulation of macropinocytosis)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-DDI-112043|reactome:R-DDI-170660|reactome:R-DDI-170670|reactome:R-DDI-202040|reactome:R-DDI-2485179|reactome:R-DDI-2514859|reactome:R-DDI-399997|reactome:R-DDI-4086398|reactome:R-DDI-416476|reactome:R-DDI-416482|reactome:R-DDI-418594|reactome:R-DDI-418597|reactome:R-DDI-434316|reactome:R-DDI-9013149|refseq:XP_638196.1|dictybase:DDB_G0285425	go:"GO:0140582"(adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway)|go:"GO:1903013"(response to differentiation-inducing factor 1)|go:"GO:1905301"(regulation of macropinocytosis)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_638833.1|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016301"(kinase activity)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043326"(chemotaxis to folate)|ensemblprotists:DDB_G0283903(gene)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0044671"(sorocarp spore cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072718"(response to cisplatin)|go:"GO:0106310"(protein serine kinase activity)|ensemblprotists:EAL65439(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0106311"|dictybase:DDB_G0283903	-	-	-	figure legend:Fig. 2E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	-	2010/08/11	2014/10/16	rogid:bxeaLhUqcblrPbTcXKq+IoSoIoU44689	rogid:JRaXTXUKigMuEZjRfRWa7oH6OMA44689	intact-crc:78CBD2516A800E7A|rigid:Qu3xH6xHMosS1foJyk/6es0i3ho	false	myc tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)