#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q92325 uniprotkb:Q12018 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247132|mint:MINT-7950701|imex:IM-14590-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950703(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950707(identity) - - crc64:22BC8B35034EDDEF comment:mint|figure legend:f1e f1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:492F9218C9413C73|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false ha tag:?-?(MINT-7950704) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12018 uniprotkb:P38352 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-21172|uniprotkb:D6VQS5|ensemblfungi:YBR280C psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:saf1_yeast(display_long)|uniprotkb:YBR2017(orf name)|uniprotkb:YBR280C(locus name)|uniprotkb:SAF1(gene name)|psi-mi:SAF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247207|mint:MINT-7950860|imex:IM-14590-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950866(identity) refseq:NP_009839.4|sgd:S000000484|mint:P38352|dip:DIP-6307N|ensemblfungi:YBR280C(gene)|ensemblfungi:YBR280C_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR036047|mint:MINT-7950862(identity) - crc64:22BC8B35034EDDEF crc64:358D751C612744BE figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:GOwHmi1aOknF0Q3p5t7VsKKIomg559292 intact-crc:0213C260BCF2BB89|rigid:pKSP3/Y3+7VhPJofgr+p64gP7X0 false - ha tag:?-?(MINT-7950863) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92325 uniprotkb:Q12018 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247183|mint:MINT-7950725|imex:IM-14590-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950727(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950731(identity) - - crc64:22BC8B35034EDDEF figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:329CDB039C5BE0B2|rigid:Bz7KlYSoB8J+4J4SWM8yyxNa6ew false flag tag:?-?(MINT-7950728) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:Q08273 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247183|mint:MINT-7950725|imex:IM-14590-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950727(identity) refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950737(identity) - - crc64:A9C3193E48CAF881 figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292 intact-crc:329CDB039C5BE0B2|rigid:Bz7KlYSoB8J+4J4SWM8yyxNa6ew false flag tag:?-?(MINT-7950728) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:P07834 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1 psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247183|mint:MINT-7950725|imex:IM-14590-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950727(identity) reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D|mint:MINT-7950733(identity) - - crc64:0348F2F8FA78F3BC figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292 intact-crc:329CDB039C5BE0B2|rigid:Bz7KlYSoB8J+4J4SWM8yyxNa6ew false flag tag:?-?(MINT-7950728) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92325 uniprotkb:P52286 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247183|mint:MINT-7950725|imex:IM-14590-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950727(identity) sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950735(identity) - - crc64:746DDE6470A69432 figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292 intact-crc:329CDB039C5BE0B2|rigid:Bz7KlYSoB8J+4J4SWM8yyxNa6ew false flag tag:?-?(MINT-7950728) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47015 uniprotkb:Q92325 intact:EBI-26073|uniprotkb:D6VW54|ensemblfungi:YJL131C intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:aim23_yeast(display_long)|uniprotkb:YJL131C(locus name)|uniprotkb:J0682(orf name)|uniprotkb:AIM23(gene name)|psi-mi:AIM23(display_short) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247280|mint:MINT-7950665|imex:IM-14590-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003667|refseq:NP_012404.1|mint:P47015|dip:DIP-5684N|ensemblfungi:YJL131C(gene)|ensemblfungi:YJL131C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0070124"(mitochondrial translational initiation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR029427|mint:MINT-7950667(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950671(identity) - - - figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:2qVCXGjy1LSZXNYhqSBevgrojNs559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:FBCAEA4F9A0EF02D|rigid:jclvA7aqiDnq8TV9pxDNZ2Z61kM false fusion protein:?-?(MINT-7950668) fusion protein:?-?(MINT-7950672) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47005 uniprotkb:Q92325 intact:EBI-26114|uniprotkb:D6VW36|ensemblfungi:YJL149W intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:das1_yeast(display_long)|uniprotkb:YJL149W(locus name)|uniprotkb:J0634(orf name)|uniprotkb:DAS1(gene name)|psi-mi:DAS1(display_short)|uniprotkb:DST1-delta 6-azauracil sensitivity protein 1(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247263|mint:MINT-7950652|imex:IM-14590-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012386.1|sgd:S000003685|dip:DIP-6404N|ensemblfungi:YJL149W(gene)|ensemblfungi:YJL149W_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|mint:MINT-7950654(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950655(identity) - crc64:C48B6CAB40920027 - figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:IBYhkN2LJ2VKoPiu8hHGbfoqD0c559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:A14B97A257646DA4|rigid:OcwCDjlqWoiMtBgpywhvg4KKw48 false fusion protein:?-?(MINT-7950657) fusion protein:?-?(MINT-7950661) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12018 uniprotkb:Q92325 intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247314|mint:MINT-7950689|imex:IM-14590-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950695(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950691(identity) - crc64:22BC8B35034EDDEF - figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:EE254B8640EAE321|rigid:fGAl4MUNhmHPmiZUG0S2BVJFooY false fusion protein:?-?(MINT-7950696) fusion protein:?-?(MINT-7950692) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06640 uniprotkb:Q92325 intact:EBI-34097|uniprotkb:D6VST5|ensemblfungi:YDR306C intact:EBI-2045650|uniprotkb:D6W240|uniprotkb:Q08175|ensemblfungi:YOL025W psi-mi:yd306_yeast(display_long)|uniprotkb:YDR306C(locus name) psi-mi:lag2_yeast(display_long)|uniprotkb:LAG2(gene name)|psi-mi:LAG2(display_short)|uniprotkb:CAND1 homolog(gene name synonym)|uniprotkb:Longevity-assurance protein 2(gene name synonym)|uniprotkb:YOL025W(locus name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247297|mint:MINT-7950677|imex:IM-14590-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010592.1|sgd:S000002714|dip:DIP-5370N|ensemblfungi:YDR306C(gene)|ensemblfungi:YDR306C_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR032675|mint:MINT-7950683(identity) sgd:S000005385|refseq:NP_014617.1|mint:Q92325|ensemblfungi:YOL025W(gene)|ensemblfungi:YOL025W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|mint:MINT-7950679(identity) - crc64:F0F69FBE96FD0155 - figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2010/07/05 2014/10/16 rogid:9PMEq+ksFP9PiUhQKlPGH/FyCzQ559292 rogid:lNrGEwMH+2MUWNxNsMBGbTRUNCg559292 intact-crc:9958C13C22749270|rigid:oPkWAj1JIXrL0ymM5WPrmwQoxrA false fusion protein:?-?(MINT-7950684) fusion protein:?-?(MINT-7950680) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38352 uniprotkb:Q12018 intact:EBI-21172|uniprotkb:D6VQS5|ensemblfungi:YBR280C intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7 psi-mi:saf1_yeast(display_long)|uniprotkb:YBR2017(orf name)|uniprotkb:YBR280C(locus name)|uniprotkb:SAF1(gene name)|psi-mi:SAF1(display_short) psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2009) pubmed:19763088|imex:IM-14590|mint:MINT-7950640|doi:10.1038/emboj.2009.268 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7247356|mint:MINT-7950877|imex:IM-14590-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009839.4|sgd:S000000484|mint:P38352|dip:DIP-6307N|ensemblfungi:YBR280C(gene)|ensemblfungi:YBR280C_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR036047|mint:MINT-7950881(identity) dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|mint:MINT-7950879(identity) - crc64:358D751C612744BE crc64:22BC8B35034EDDEF figure legend:f7|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/05 2014/10/16 rogid:GOwHmi1aOknF0Q3p5t7VsKKIomg559292 rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292 intact-crc:02309BCAFD92A1D3|rigid:pKSP3/Y3+7VhPJofgr+p64gP7X0 false glutathione s tranferase tag:?-?(MINT-7950882) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot)