#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q58108	uniprotkb:P54066	intact:EBI-2944241|ensemblbacteria:AAB98690	intact:EBI-2944269|ensemblbacteria:AAB99207	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944255|imex:IM-19212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	figure legend:Figs. 1B, 1C|comment:Assembly required the presence of the sR8 small RNA|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	intact-crc:4ADE98495AC2746E	false	flag tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58108	intact:EBI-2944298	intact:EBI-2944241|ensemblbacteria:AAB98690	-	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:sr8_metja_rna(display_short)|psi-mi:EBI-2944298(display_long)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:2190(methanocaldococcus jannaschii)|taxid:2190(Methanocaldococcus jannaschii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944255|imex:IM-19212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	-	-	-	-	figure legend:Figs. 1B, 1C|comment:Assembly required the presence of the sR8 small RNA|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	-	intact-crc:4ADE98495AC2746E	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58108	uniprotkb:Q58105	intact:EBI-2944241|ensemblbacteria:AAB98690	intact:EBI-2944259|ensemblbacteria:AAB98689	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944255|imex:IM-19212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	-	-	-	figure legend:Figs. 1B, 1C|comment:Assembly required the presence of the sR8 small RNA|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	intact-crc:4ADE98495AC2746E	false	flag tag:n-n	sufficient binding region:1-367	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58105	uniprotkb:P54066	intact:EBI-2944259|ensemblbacteria:AAB98689	intact:EBI-2944269|ensemblbacteria:AAB99207	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944476|imex:IM-19212-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	figure legend:Fig. 3B|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	intact-crc:C9FC7857725D796F|rigid:VOFSesDLgghjpbx2m8ILt1Ov60k	false	sufficient binding region:121-367	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54066	intact:EBI-2944298	intact:EBI-2944269|ensemblbacteria:AAB99207	-	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:sr8_metja_rna(display_short)|psi-mi:EBI-2944298(display_long)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:2190(methanocaldococcus jannaschii)|taxid:2190(Methanocaldococcus jannaschii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944484|imex:IM-19212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	-	figure legend:Fig. 3A|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	-	intact-crc:543DBE5C64B7647B	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54066	uniprotkb:Q58105	intact:EBI-2944269|ensemblbacteria:AAB99207	intact:EBI-2944259|ensemblbacteria:AAB98689	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944484|imex:IM-19212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	-	-	-	figure legend:Fig. 3A|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	intact-crc:543DBE5C64B7647B	false	his tag:n-n	sufficient binding region:121-367	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58108	uniprotkb:P54066	intact:EBI-2944241|ensemblbacteria:AAB98690	intact:EBI-2944269|ensemblbacteria:AAB99207	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944453|imex:IM-19212-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	figure legend:Fig. 2A|comment:The EM structure was refined to a resolution of 27A|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	intact-crc:0FFA46EC7169B5DD	false	flag tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58108	intact:EBI-2944298	intact:EBI-2944241|ensemblbacteria:AAB98690	-	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:sr8_metja_rna(display_short)|psi-mi:EBI-2944298(display_long)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:2190(methanocaldococcus jannaschii)|taxid:2190(Methanocaldococcus jannaschii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944453|imex:IM-19212-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	-	-	-	-	figure legend:Fig. 2A|comment:The EM structure was refined to a resolution of 27A|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	-	intact-crc:0FFA46EC7169B5DD	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58108	uniprotkb:Q58105	intact:EBI-2944241|ensemblbacteria:AAB98690	intact:EBI-2944259|ensemblbacteria:AAB98689	psi-mi:flpa_metja(display_long)|uniprotkb:flpA(gene name)|psi-mi:flpA(display_short)|uniprotkb:MJ0697(locus name)	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944453|imex:IM-19212-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98690(transcript)|ensemblbacteria:MJ_0697(gene)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|rcsb pdb:1FBN|rcsb pdb:1G8S|refseq:WP_010870202.1|interpro:IPR029063	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	-	-	-	figure legend:Fig. 2A|comment:The EM structure was refined to a resolution of 27A|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:KNCMj4zwQGr8Qo4q+1OPNAYKXlI243232	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	intact-crc:0FFA46EC7169B5DD	false	flag tag:n-n	sufficient binding region:1-367	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54066	intact:EBI-2944298	intact:EBI-2944269|ensemblbacteria:AAB99207	-	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:sr8_metja_rna(display_short)|psi-mi:EBI-2944298(display_long)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:2190(methanocaldococcus jannaschii)|taxid:2190(Methanocaldococcus jannaschii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944466|imex:IM-19212-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	-	figure legend:Fig. 3A, 4A-C|comment:The Nop5 mutant lacking the coiled coil region still assembles into complexes containing all box C/D sRNP components, including the sRNA and L7, but they are not di-sRNPs i.e. are not catalytically active suggesting correct binding and assembly is impaired.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	-	intact-crc:49295B54506DF67E	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54066	uniprotkb:Q58105	intact:EBI-2944269|ensemblbacteria:AAB99207	intact:EBI-2944259|ensemblbacteria:AAB98689	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944466|imex:IM-19212-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	-	-	-	figure legend:Fig. 3A, 4A-C|comment:The Nop5 mutant lacking the coiled coil region still assembles into complexes containing all box C/D sRNP components, including the sRNA and L7, but they are not di-sRNPs i.e. are not catalytically active suggesting correct binding and assembly is impaired.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	intact-crc:49295B54506DF67E	false	his tag:n-n	necessary binding region:123-241	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q58105	uniprotkb:P54066	intact:EBI-2944259|ensemblbacteria:AAB98689	intact:EBI-2944269|ensemblbacteria:AAB99207	psi-mi:y694_metja(display_long)|uniprotkb:MJ0694(locus name)	psi-mi:rl7a_metja(display_long)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:MJ1203(locus name)	psi-mi:"MI:0040"(electron microscopy)	Bleichert et al. (2009)	pubmed:19745151|imex:IM-19212	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2945585|imex:IM-19212-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAB98689(transcript)|ensemblbacteria:MJ_0694(gene)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|interpro:IPR012976(NOSIC)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|refseq:WP_010870199.1|rcsb pdb:3T7Z|interpro:IPR042239|interpro:IPR029012|interpro:IPR036070	ensemblbacteria:AAB99207(transcript)|ensemblbacteria:MJ_1203(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0003723"(RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR000948(Ribosomal protein HS6)|rcsb pdb:1RA4|rcsb pdb:1SDS|rcsb pdb:1XBI|refseq:WP_010870715.1|rcsb pdb:3PAF|interpro:IPR029064|rcsb pdb:6K0A|rcsb pdb:6K0B	-	-	-	figure legend:Fig. 3B|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:Ql/riQn8NcC2z1rEwGt3Io9wHbw243232	rogid:28Ee2QX9GrCuY42IbpsSCjIdgGA243232	intact-crc:7809DF249E4DB89B|rigid:VOFSesDLgghjpbx2m8ILt1Ov60k	false	sufficient binding region:121-367	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)