#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P62330	uniprotkb:O60271	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7140974|mint:MINT-7915283|imex:IM-14583-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7915286(identity)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7915285(identity)	-	comment:"Stoichiometry: 2.2"	comment:"Stoichiometry: 2.2"	figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/22	2022/01/21	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	intact-crc:D27B2348F9DD002C|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:13-175(MINT-7915292)	binding-associated region:392-462(MINT-7915288)	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P62330	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141018|mint:MINT-7922407|imex:IM-14583-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922409(identity)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922413(identity)	-	comment:"Stoichiometry: 2.2"	comment:"Stoichiometry: 2.2"	figure legend:f3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/22	2022/01/21	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:270EF34A20461A80|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:392-462(MINT-7922410)	binding-associated region:13-175(MINT-7922414)	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:O60271	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141074|mint:MINT-7922436|imex:IM-14583-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922438(identity)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922438(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	intact-crc:6243ABADA2937C99|rigid:1+dTf1aCasv6quKd3jLxqQuAH4E	false	binding-associated region:392-462(MINT-7922439)	binding-associated region:392-462(MINT-7922439)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62330	uniprotkb:O60271	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141038|mint:MINT-7922423|imex:IM-14583-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922429(identity)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922425(identity)	-	comment:"Stoichiometry: 1.2"	comment:"Stoichiometry: 2.1"	figure legend:f3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/22	2022/01/21	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	intact-crc:895D48AECEC2F6FE|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:13-175(MINT-7922430)	binding-associated region:392-462(MINT-7922426)	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P62330	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141095|mint:MINT-7922449|imex:IM-14583-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922451(identity)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922455(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.2x10^-7(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:25541DD626FB3C4C|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:392-462(MINT-7922452)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62330	uniprotkb:O60271	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141127|mint:MINT-7922462|imex:IM-14583-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922469(identity)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922465(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.15x10^-5(molar)	2010/06/22	2014/10/16	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	intact-crc:A7B2D4C8D9FBF8E5|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	-	binding-associated region:392-462(MINT-7922466)|mutation decreasing interaction:416-416(MINT-7922475)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P62330	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141167|mint:MINT-7922481|imex:IM-14583-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922484(identity)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922490(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.6x10^-6(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:687A294C52B63C0F|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	mutation decreasing interaction:421-421(MINT-7922485)|binding-associated region:392-462(MINT-7922487)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P84077	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141242|mint:MINT-7922541|imex:IM-14583-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922544(identity)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|mint:MINT-7922550(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:9.8x10^-6(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:80DD2AAA159E72E2|rigid:UzUsBSGOg1swlo6mmusM0KqoXLg	false	binding-associated region:392-462(MINT-7922545)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P62330	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141207|mint:MINT-7922515|imex:IM-14583-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922518(identity)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922524(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.7x10^-7(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:BFB1CA100E8C929A|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:392-462(MINT-7922521)	binding-associated region:13-175(MINT-7922525)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P62330	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141187|mint:MINT-7922498|imex:IM-14583-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922501(identity)	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-7922507(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.1x10^-6(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:8BADC6F7C434D6E5|rigid:NxuUbGaZ4K0PKVh3WSLeSA6jEUE	false	binding-associated region:392-462(MINT-7922502)|mutation decreasing interaction:425-425(MINT-7922504)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P84077	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141258|mint:MINT-7922558|imex:IM-14583-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922561(identity)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|mint:MINT-7922565(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.0x10^-6(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:46355CF33AC8AE6F|rigid:UzUsBSGOg1swlo6mmusM0KqoXLg	false	binding-associated region:392-462(MINT-7922562)	mutation increasing interaction:57-57(MINT-7922569)|mutation increasing interaction:83-83(MINT-7922572)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60271	uniprotkb:P84077	intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Isabet et al. (2009)	pubmed:19644450|imex:IM-14583|mint:MINT-7915267|doi:10.1038/emboj.2009.209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7141282|mint:MINT-7922576|imex:IM-14583-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-7922579(identity)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|mint:MINT-7922583(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f5c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.8x10^-7(molar)	2010/06/22	2014/10/16	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:B77862D25E1DADFC|rigid:UzUsBSGOg1swlo6mmusM0KqoXLg	false	binding-associated region:392-462(MINT-7922580)	mutation increasing interaction:57-57(MINT-7922586)|mutation increasing interaction:62-62(MINT-7922591)|mutation increasing interaction:64-64(MINT-7922594)|mutation increasing interaction:83-83(MINT-7922584)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)