#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UYX8 uniprotkb:Q9V2E8 intact:EBI-7103152|ensemblbacteria:CAB50284|uniprotkb:G8ZHI5|intact:MINT-7906062 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 psi-mi:pcna_pyrab(display_long)|uniprotkb:pcn(gene name)|psi-mi:pcn(display_short)|uniprotkb:Proliferating cell nuclear antigen homolog(gene name synonym)|uniprotkb:PAB1465(orf name)|uniprotkb:PYRAB13790(locus name) psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7103172|mint:MINT-7906076|imex:IM-14609-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9UYX8|ensemblbacteria:CAB50284(transcript)|ensemblbacteria:PAB1465(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0030337"(DNA polymerase processivity factor activity)|rcsb pdb:6T7X|rcsb pdb:6T7Y|rcsb pdb:6T8H|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|refseq:WP_010868494.1|mint:MINT-7906079(identity) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906078(identity) - comment:mint comment:mint figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.5x10^-8(molar) 2010/06/17 2014/10/16 rogid:4d7gwuSl1HOW9Inqa6K7nYoMS4g272844 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 intact-crc:EC3183015A61D947|rigid:KhAR4yqWk1kyYPOYKpu1Vng5p3M false - his tag:?-?(MINT-7906389) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V2E8 uniprotkb:Q9V135 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103352|ensemblbacteria:CAB49516|uniprotkb:G8ZJ59|intact:MINT-7906137 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:top6b_pyrab(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)|uniprotkb:PAB0407(orf name)|uniprotkb:PYRAB05940(locus name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9V135|interpro:IPR036890|ensemblbacteria:CAB49516(transcript)|ensemblbacteria:PAB0407(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|refseq:WP_010867718.1|mint:MINT-7906155(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:TTovfV0reXPo/1nA/PYea2hq0DU272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9V2G4 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103276|ensemblbacteria:CAB49034|intact:MINT-7906090|uniprotkb:G8ZFU5 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:rfcs_pyrab(display_long)|uniprotkb:rfcS(gene name)|psi-mi:rfcS(display_short)|uniprotkb:Clamp loader small subunit(gene name synonym)|uniprotkb:PabRFC small subunit(gene name synonym)|uniprotkb:PAB0068(orf name)|uniprotkb:PYRAB01100(locus name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9V2G4|ensemblbacteria:CAB49034(transcript)|ensemblbacteria:PAB0068(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016539"(intein-mediated protein splicing)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR027434|interpro:IPR013748(Replication factor C)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004860(LAGLIDADG DNA endonuclease)|interpro:IPR030934|interpro:IPR036388|interpro:IPR036390|interpro:IPR036844|mint:MINT-7906122(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Uyen6epH47c/M2CMxFQqT8svP9Q272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9UYX8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103152|ensemblbacteria:CAB50284|uniprotkb:G8ZHI5|intact:MINT-7906062 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:pcna_pyrab(display_long)|uniprotkb:pcn(gene name)|psi-mi:pcn(display_short)|uniprotkb:Proliferating cell nuclear antigen homolog(gene name synonym)|uniprotkb:PAB1465(orf name)|uniprotkb:PYRAB13790(locus name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9UYX8|ensemblbacteria:CAB50284(transcript)|ensemblbacteria:PAB1465(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0030337"(DNA polymerase processivity factor activity)|rcsb pdb:6T7X|rcsb pdb:6T7Y|rcsb pdb:6T8H|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|refseq:WP_010868494.1|mint:MINT-7906083(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:4d7gwuSl1HOW9Inqa6K7nYoMS4g272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9V1Z5 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103372|ensemblbacteria:CAB49203|intact:MINT-7906173 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:q9v1z5_pyrab(display_long)|uniprotkb:PAB0190(orf name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9V1Z5|ensemblbacteria:CAB49203(transcript)|ensemblbacteria:PAB0190(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR027417|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR041663|interpro:IPR039686|interpro:IPR041755|mint:MINT-7906195(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Or5nWxx6EF26XTQrr/0PwcL3Nh8272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9V2G3 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103312|ensemblbacteria:CAB49035|intact:MINT-7906123|uniprotkb:G8ZFU6 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:rfcl_pyrab(display_long)|uniprotkb:rfcL(gene name)|psi-mi:rfcL(display_short)|uniprotkb:Clamp loader large subunit(gene name synonym)|uniprotkb:PabRFC large subunit(gene name synonym)|uniprotkb:PAB0069(orf name)|uniprotkb:PYRAB01110(locus name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9V2G3|refseq:WP_010867235.1|ensemblbacteria:CAB49035(transcript)|ensemblbacteria:PAB0069(gene)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|interpro:IPR023935|mint:MINT-7906121(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:QuJTI8Z8ilgxK287nCOGwcHELnA272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9V134 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103331|ensemblbacteria:CAB49517|intact:MINT-7906156|uniprotkb:G8ZJ60 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:top6a_pyrab(display_long)|uniprotkb:Type II DNA topoisomerase VI subunit A(gene name synonym)|uniprotkb:PAB2411(orf name)|uniprotkb:PYRAB05950(locus name)|uniprotkb:top6A(gene name)|psi-mi:top6A(display_short) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7103395|mint:MINT-7906080|imex:IM-14609-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906082(identity) mint:Q9V134|refseq:WP_010867719.1|ensemblbacteria:CAB49517(transcript)|ensemblbacteria:PAB2411(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR004085(DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|mint:MINT-7906172(identity) - comment:mint comment:mint figure legend:sf1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:vVLybb9Anf7oPR4tdBqkA3ykeO0272844 intact-crc:225409094FE491B3|rigid:1NrOaSOWpUeHIY0rOmEUkTMW8Tw false his tag:?-?(MINT-7906393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9V2E8 uniprotkb:Q9UYX8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103152|ensemblbacteria:CAB50284|uniprotkb:G8ZHI5|intact:MINT-7906062 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:pcna_pyrab(display_long)|uniprotkb:pcn(gene name)|psi-mi:pcn(display_short)|uniprotkb:Proliferating cell nuclear antigen homolog(gene name synonym)|uniprotkb:PAB1465(orf name)|uniprotkb:PYRAB13790(locus name) psi-mi:"MI:0096"(pull down) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7103458|mint:MINT-7906375|imex:IM-14609-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906378(identity) mint:Q9UYX8|ensemblbacteria:CAB50284(transcript)|ensemblbacteria:PAB1465(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0030337"(DNA polymerase processivity factor activity)|rcsb pdb:6T7X|rcsb pdb:6T7Y|rcsb pdb:6T8H|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|refseq:WP_010868494.1|mint:MINT-7906380(identity) - comment:mint comment:mint figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:4d7gwuSl1HOW9Inqa6K7nYoMS4g272844 intact-crc:34CDA7962B4D6096|rigid:KhAR4yqWk1kyYPOYKpu1Vng5p3M false his tag:?-?(MINT-7906384) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V2E8 uniprotkb:Q9V2E8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:"MI:0114"(x-ray crystallography) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7103495|mint:MINT-7906248|imex:IM-14609-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906250(identity) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906250(identity) - comment:mint|comment:"Stoichiometry: 2.0" comment:mint|comment:"Stoichiometry: 2.0" figure legend:f2d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 intact-crc:9844F46B02D26F88|rigid:juENIHVvRzuhZ65b8QTGs4X67UU false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V2E8 uniprotkb:Q9V2E8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:"MI:0114"(x-ray crystallography) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7103504|mint:MINT-7906258|imex:IM-14609-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906260(identity) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906260(identity) - comment:mint|comment:"Stoichiometry: 4.0" comment:mint|comment:"Stoichiometry: 4.0" figure legend:f2d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 intact-crc:EEB4502407BFC157|rigid:juENIHVvRzuhZ65b8QTGs4X67UU false - - 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V2E8 uniprotkb:Q9V2E8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:"MI:0071"(molecular sieving) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7103523|mint:MINT-7906274|imex:IM-14609-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906276(identity) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906276(identity) - comment:mint|comment:"Stoichiometry: 2.0" comment:mint|comment:"Stoichiometry: 2.0" figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 intact-crc:B4CCE51EB6FB0FC9|rigid:juENIHVvRzuhZ65b8QTGs4X67UU false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V2E8 uniprotkb:Q9V2E8 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 intact:EBI-7103178|ensemblbacteria:CAB49050|uniprotkb:G8ZFW1|intact:MINT-7906054 psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:nucs_pyrab(display_long)|uniprotkb:nucS(gene name)|psi-mi:nucS(display_short)|uniprotkb:Nuclease for ssDNA(gene name synonym)|uniprotkb:PAB2263(orf name)|uniprotkb:PYRAB01260(locus name) psi-mi:"MI:0038"(dynamic light scattering) Ren et al. (2009) pubmed:19609302|imex:IM-14609|mint:MINT-7906046|doi:10.1038/emboj.2009.192 taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") taxid:272844(pyrab)|taxid:272844("Pyrococcus abyssi (strain GE5 / Orsay)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7103555|mint:MINT-7906266|imex:IM-14609-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906268(identity) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|mint:Q9V2E8|refseq:WP_010867250.1|ensemblbacteria:CAB49050(transcript)|ensemblbacteria:PAB2263(gene)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0003677"(DNA binding)|go:"GO:0042802"(identical protein binding)|rcsb pdb:2VLD|go:"GO:0005737"(cytoplasm)|interpro:IPR002793(Protein of unknown function DUF91)|mint:MINT-7906268(identity) - comment:mint|comment:"Stoichiometry: 2.0" comment:mint|comment:"Stoichiometry: 2.0" figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/17 2014/10/16 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 rogid:Aq6BNXw55V2Oiz4Fsx7o5Hba2Cw272844 intact-crc:EAB200E8644BFDAD|rigid:juENIHVvRzuhZ65b8QTGs4X67UU false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)