#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q00961 uniprotkb:P62260 intact:EBI-631045 intact:EBI-356462|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSRNOP00000007100 psi-mi:nmde3_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2C(gene name synonym)|uniprotkb:Grin2c(gene name)|psi-mi:Grin2c(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-3(gene name synonym) psi-mi:1433e_rat(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)|uniprotkb:Mitochondrial import stimulation factor L subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chen et al. (2009) pubmed:19477150|mint:MINT-8008969|doi:10.1016/j.neuron.2009.04.015 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7019775|mint:MINT-8008979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2739|refseq:NP_036707.3|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033058"(directional locomotion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|refseq:XP_006247769.1|refseq:XP_006247771.1|interpro:IPR028082|refseq:XP_017452475.1|refseq:XP_017452476.1|refseq:XP_017452477.1|refseq:XP_017452478.1|refseq:XP_017452479.1|refseq:XP_017452480.1|refseq:XP_017452481.1|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-8008983(identity)|uniprotkb:Q00961(original identifier) rgd:62000|refseq:NP_113791.1|ensembl:ENSRNOG00000005290(gene)|ensembl:ENSRNOT00000007100(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62260|reactome:R-RNO-111447|reactome:R-RNO-2028269|reactome:R-RNO-205025|reactome:R-RNO-2565942|reactome:R-RNO-3371453|reactome:R-RNO-3371511|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-8876198|dip:DIP-37260N|mint:MINT-8008980(identity)|uniprotkb:P62260(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:DNWgJGwL2992SEfrd3xZwHfJmdY10116 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10116 intact-crc:32802832DB9DF829|rigid:RrsWmIImd70XxLdXiWGVVHPR0eo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)