#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9CWE6 uniprotkb:Q9R1M5 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2905834|imex:IM-20505-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:85F09B958F9FC1F4|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CWE6 uniprotkb:Q9CWU5 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2905834|imex:IM-20505-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 - - - figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 intact-crc:85F09B958F9FC1F4|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CWE6 uniprotkb:Q9WVB3 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2905834|imex:IM-20505-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:85F09B958F9FC1F4|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CWE6 uniprotkb:Q9CWU5 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911160|imex:IM-20505-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 intact-crc:854379603E997745|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWE6 uniprotkb:Q9WVB3 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911160|imex:IM-20505-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:854379603E997745|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWE6 uniprotkb:Q9R1M5 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911160|imex:IM-20505-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:854379603E997745|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVB3 uniprotkb:Q9R1M5 intact:EBI-2905816|ensembl:ENSMUSP00000071905 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911626|imex:IM-20505-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:EEF4996C3C11D74C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVB3 uniprotkb:Q9CWE6 intact:EBI-2905816|ensembl:ENSMUSP00000071905 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911626|imex:IM-20505-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:EEF4996C3C11D74C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVB3 uniprotkb:Q9CWU5 intact:EBI-2905816|ensembl:ENSMUSP00000071905 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911626|imex:IM-20505-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 - - - figure legend:Fig 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2010/08/11 2014/10/16 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 intact-crc:EEF4996C3C11D74C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWE6 uniprotkb:Q9R1M5 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911927|imex:IM-20505-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:410A65DA72C9FC03|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false enhanced green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9CWE6 uniprotkb:Q9WVB3 intact:EBI-2905695|ensembl:ENSMUSP00000034900 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911927|imex:IM-20505-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:410A65DA72C9FC03|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false enhanced green fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R1M5 uniprotkb:Q9CWU5 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911937|imex:IM-20505-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 - - - figure legend:Fig 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 intact-crc:BB10AC38327183FE|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911937|imex:IM-20505-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:BB10AC38327183FE|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false myc tag:?-? enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911937|imex:IM-20505-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:BB10AC38327183FE|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false myc tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9CWU5 uniprotkb:Q9R1M5 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911949|imex:IM-20505-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:F5F6CD750C0E2A59|rigid:ITn7Ga2cusklX1X8iwejQAchdbY false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9WVB3 uniprotkb:Q9R1M5 intact:EBI-2905816|ensembl:ENSMUSP00000071905 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911970|imex:IM-20505-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:3A11E65C3DD836C4|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVB3 uniprotkb:Q9CWE6 intact:EBI-2905816|ensembl:ENSMUSP00000071905 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1262"(I2D) intact:EBI-2911970|imex:IM-20505-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2010/08/11 2014/10/16 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:3A11E65C3DD836C4|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWU5 uniprotkb:Q9R1M5 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-2922723|imex:IM-20505-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 - - - figure legend:Fig 4f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovum)|taxid:10090(Mus musculus egg cell) - 2010/08/11 2014/10/16 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 intact-crc:A0E4496170E9392C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWU5 uniprotkb:Q9CWE6 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-2922723|imex:IM-20505-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 4f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovum)|taxid:10090(Mus musculus egg cell) - 2010/08/11 2014/10/16 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:A0E4496170E9392C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CWU5 uniprotkb:Q9WVB3 intact:EBI-2905804|ensembl:ENSMUSP00000034737|uniprotkb:A7YIL2|uniprotkb:Q9CRD6 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:khdc3_mouse(display_long)|uniprotkb:Khdc3(gene name)|psi-mi:Khdc3(display_short)|uniprotkb:Protein Filia(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-2922723|imex:IM-20505-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|rcsb pdb:3V69|ensembl:ENSMUSG00000092622(gene)|ensembl:ENSMUST00000034737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_080166.1|refseq:NP_001298035.1 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 4f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovum)|taxid:10090(Mus musculus egg cell) - 2010/08/11 2014/10/16 rogid:JJl+s+uEe07WECBh30lSfLShBrI10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:A0E4496170E9392C|rigid:PP4PCF2jV5qC/xCZEX2PJ4IhMAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922738|imex:IM-20505-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 go:"GO:0044448"(obsolete cell cortex part) - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovum)|taxid:10090(Mus musculus egg cell) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:83E60F0AFA7F3B83|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922738|imex:IM-20505-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 go:"GO:0044448"(obsolete cell cortex part) - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovum)|taxid:10090(Mus musculus egg cell) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:83E60F0AFA7F3B83|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922753|imex:IM-20505-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-zygote)|taxid:10090(Mus musculus zygote) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:83A758ECFAC436A3|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922753|imex:IM-20505-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-zygote)|taxid:10090(Mus musculus zygote) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:83A758ECFAC436A3|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922767|imex:IM-20505-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:86DC5713FEDA5E73|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922767|imex:IM-20505-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:86DC5713FEDA5E73|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922781|imex:IM-20505-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-morula)|taxid:10090(Mus musculus morula) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:22CE845499D7B3C8|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922781|imex:IM-20505-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-morula)|taxid:10090(Mus musculus morula) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:22CE845499D7B3C8|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9CWE6 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905695|ensembl:ENSMUSP00000034900 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:ooep_mouse(display_long)|uniprotkb:Ooep(gene name)|psi-mi:Ooep(display_short)|uniprotkb:Oep19(gene name synonym)|uniprotkb:Sddr(gene name synonym)|uniprotkb:Oocyte- and embryo-specific protein 19(gene name synonym)|uniprotkb:STAT3 downstream gene and differentiation regulator(gene name synonym)|uniprotkb:Factor located in oocytes permitting embryonic development(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922795|imex:IM-20505-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000032346(gene)|ensembl:ENSMUST00000034900(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031297"(replication fork processing)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR031952|interpro:IPR036612|interpro:IPR040068|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|refseq:NP_080756.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-blastocyst)|taxid:10090(Mus musculus blastocyst) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:xPn0sIC09O6FmHXjj7T11znmKjQ10090 intact-crc:F39447B6B15FF0F5|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1M5 uniprotkb:Q9WVB3 intact:EBI-2905719|uniprotkb:Q3UXD0|uniprotkb:Q53ZD5|uniprotkb:Q6VSF9|uniprotkb:Q6VSG0|uniprotkb:Q6VSG1|uniprotkb:Q6VSG2|uniprotkb:Q6VSG3|uniprotkb:Q6VSG4|uniprotkb:Q6VSG5|uniprotkb:Q6XZF2|uniprotkb:Q7TPU9|uniprotkb:Q9JLR2 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nalp5_mouse(display_long)|uniprotkb:Nlrp5(gene name)|psi-mi:Nlrp5(display_short)|uniprotkb:Mater(gene name synonym)|uniprotkb:Nalp5(gene name synonym)|uniprotkb:Maternal antigen that embryos require(gene name synonym)|uniprotkb:Ooplasm-specific protein 1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2008) pubmed:18804437|imex:IM-20505 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-2922795|imex:IM-20505-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007566"(embryo implantation)|go:"GO:0009566"(fertilization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015631"(tubulin binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032879"(regulation of localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0045179"(apical cortex)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001292786.1|refseq:NP_001034232.1|refseq:NP_035990.1|ensembl:ENSMUSG00000015721|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267 ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1 - - - figure legend:Fig 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-blastocyst)|taxid:10090(Mus musculus blastocyst) - 2010/08/11 2014/10/16 rogid:Wy6tI+0jBJtjLYZFqimyYq2BDf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 intact-crc:F39447B6B15FF0F5|rigid:WCjbvmdYbP8fhFBSDuLtFQBAQzs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)