#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21802 uniprotkb:P63104 intact:EBI-1028658|uniprotkb:P18443|uniprotkb:Q01742|uniprotkb:Q12922|uniprotkb:Q14300|uniprotkb:Q14301|uniprotkb:Q14302|uniprotkb:Q14303|uniprotkb:Q14304|uniprotkb:Q14305|uniprotkb:Q14672|uniprotkb:Q14718|uniprotkb:Q14719|uniprotkb:Q86YI4|uniprotkb:Q96KL9|uniprotkb:Q96KM0|uniprotkb:Q96KM1|uniprotkb:Q96KM2|uniprotkb:Q9NZU2|uniprotkb:Q9NZU3|uniprotkb:Q9UD01|uniprotkb:Q9UD02|uniprotkb:Q9UIH3|uniprotkb:Q9UIH4|uniprotkb:Q9UIH5|uniprotkb:Q9UIH6|uniprotkb:Q9UIH7|uniprotkb:Q9UIH8|uniprotkb:Q9UM87|uniprotkb:Q9UMC6|uniprotkb:Q9UNS7|uniprotkb:Q9UQH7|uniprotkb:Q9UQH8|uniprotkb:Q9UQH9|uniprotkb:Q9UQI0|uniprotkb:Q1KHY5|ensembl:ENSP00000351276|uniprotkb:B4DFC2|uniprotkb:E7EVR6|uniprotkb:E9PCR0|uniprotkb:Q8IXC7 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:fgfr2_human(display_long)|uniprotkb:FGFR2(gene name)|psi-mi:FGFR2(display_short)|uniprotkb:BEK(gene name synonym)|uniprotkb:KSAM(gene name synonym)|uniprotkb:Keratinocyte growth factor receptor(gene name synonym)|uniprotkb:KGFR(gene name synonym)|uniprotkb:K-sam(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Lonic et al. (2008) pubmed:18332103|mint:MINT-8008273|doi:10.1128/MCB.01837-07 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7845252|mint:MINT-8008282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000132.3|refseq:NP_001138385.1|refseq:NP_001138386.1|refseq:NP_001138387.1|refseq:NP_001138388.1|refseq:NP_001138389.1|refseq:NP_001138390.1|refseq:NP_001138391.1|refseq:NP_075259.4|ensembl:ENSG00000066468(gene)|ensembl:ENST00000358487(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0035265"(organ growth)|go:"GO:0035602"(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell)|go:"GO:0035603"(fibroblast growth factor receptor signaling pathway involved in hemopoiesis)|go:"GO:0035604"(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048565"(digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060174"(limb bud formation)|go:"GO:0060348"(bone development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060512"(prostate gland morphogenesis)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0060595"(fibroblast growth factor receptor signaling pathway involved in mammary gland specification)|go:"GO:0060601"(lateral sprouting from an epithelium)|go:"GO:0060615"(mammary gland bud formation)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0060667"(branch elongation involved in salivary gland morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060688"(regulation of morphogenesis of a branching structure)|go:"GO:0060915"(mesenchymal cell differentiation involved in lung development)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|interpro:IPR041159|mint:P21802|rcsb pdb:1DJS|rcsb pdb:1E0O|rcsb pdb:1EV2|rcsb pdb:1GJO|rcsb pdb:1II4|rcsb pdb:1IIL|rcsb pdb:1NUN|rcsb pdb:1OEC|rcsb pdb:1WVZ|rcsb pdb:2FDB|rcsb pdb:2PSQ|rcsb pdb:2PVF|rcsb pdb:2PVY|rcsb pdb:2PWL|rcsb pdb:2PY3|rcsb pdb:2PZ5|rcsb pdb:2PZP|rcsb pdb:2PZR|rcsb pdb:2Q0B|rcsb pdb:3B2T|rcsb pdb:3CAF|rcsb pdb:3CLY|rcsb pdb:3CU1|rcsb pdb:3DAR|rcsb pdb:3EUU|rcsb pdb:3OJ2|rcsb pdb:3OJM|rcsb pdb:3RI1|rcsb pdb:4J23|rcsb pdb:4J95|rcsb pdb:4J96|rcsb pdb:4J97|rcsb pdb:4J98|rcsb pdb:4J99|rcsb pdb:4WV1|rcsb pdb:5EG3|rcsb pdb:5UGL|rcsb pdb:5UGX|rcsb pdb:5UHN|rcsb pdb:5UI0|rcsb pdb:6AGX|rcsb pdb:6LVK|rcsb pdb:6LVL|rcsb pdb:6V6Q|rcsb pdb:7KIA|rcsb pdb:7KIE|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-190375|reactome:R-HSA-5654700|reactome:R-HSA-5654727|reactome:R-HSA-5655253|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851708|reactome:R-HSA-8853333|reactome:R-HSA-190377|reactome:R-HSA-2023837|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-5654221|reactome:R-HSA-5654695|reactome:R-HSA-5654699|refseq:NP_001307583.1|refseq:NP_001307587.1|refseq:NP_075418.1|dip:DIP-3788N|mint:MINT-8008286(identity)|uniprotkb:P21802(original identifier) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8008283(identity)|uniprotkb:P63104(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:XW6x8AHgdb29IL3MhUFWpv4jaqE9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:30F3BF14F6DC75C5|rigid:YJFJUtQDAI8gGjiKXHW4QhxT6Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)