#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P62258	uniprotkb:P56524	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Paroni et al. (2008)	pubmed:18045992|mint:MINT-8008084|doi:10.1091/mbc.E07-06-0623	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7699629|mint:MINT-8008092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|mint:MINT-8008093(identity)|uniprotkb:P62258(original identifier)	ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|mint:MINT-8008096(identity)|uniprotkb:P56524(original identifier)	-	-	-	comment:homomint|comment:domino|comment:mint	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/21	2014/10/16	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	intact-crc:B576CD222FBB1809|rigid:bWTyoXzPSp6lB7kuDHnOjvpdExQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56524	uniprotkb:P61981	intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Paroni et al. (2008)	pubmed:18045992|mint:MINT-8008084|doi:10.1091/mbc.E07-06-0623	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7699642|mint:MINT-8008099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|mint:MINT-8008103(identity)|uniprotkb:P56524(original identifier)	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N|mint:MINT-8008100(identity)|uniprotkb:P61981(original identifier)	-	-	-	comment:homomint|comment:domino|comment:mint	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/21	2014/10/16	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	intact-crc:A91F1ACF19BF8BBB|rigid:vokX7DFS6DjVvz8A3knJMtulc2k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56524	uniprotkb:Q04917	intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606	intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Paroni et al. (2008)	pubmed:18045992|mint:MINT-8008084|doi:10.1091/mbc.E07-06-0623	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7699668|mint:MINT-8008113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|mint:MINT-8008117(identity)|uniprotkb:P56524(original identifier)	go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-8008114(identity)|uniprotkb:Q04917(original identifier)	-	-	-	comment:homomint|comment:domino|comment:mint	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/21	2014/10/16	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	intact-crc:52694487A415F420|rigid:zzrqFVw9CJjFLse79NT/y2cgj1Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27348	uniprotkb:P56524	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Paroni et al. (2008)	pubmed:18045992|mint:MINT-8008084|doi:10.1091/mbc.E07-06-0623	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7699655|mint:MINT-8008106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N|mint:MINT-8008107(identity)|uniprotkb:P27348(original identifier)	ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|mint:MINT-8008110(identity)|uniprotkb:P56524(original identifier)	-	-	-	comment:homomint|comment:domino|comment:mint	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/21	2014/10/16	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	intact-crc:669D2801F8BD6614|rigid:bQGLpqaAJ2dzbnhLTsDVthJIHcs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)