#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EG05 uniprotkb:G5EGK5 intact:EBI-329656|ensemblmetazoa:W08D2.1.1 intact:EBI-2930565|ensemblmetazoa:C01G6.8a.1|uniprotkb:G5ECA5|uniprotkb:Q38G54 psi-mi:g5eg05_caeel(display_long)|uniprotkb:W08D2.1(orf name)|uniprotkb:egl-20(gene name)|psi-mi:egl-20(display_short)|uniprotkb:CELE_W08D2.1(orf name) psi-mi:cam1_caeel(display_long)|uniprotkb:cam-1(gene name)|psi-mi:cam-1(display_short)|uniprotkb:kin-8(gene name synonym)|uniprotkb:C01G6.8(orf name) psi-mi:"MI:0400"(affinity technology) Green et al. (2007) pubmed:17942487|imex:IM-20520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930604|imex:IM-20520-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|refseq:NP_501754.1|uniprotkb:Q9TVJ1(uniprot-removed-ac)|interpro:IPR043158|wormbase:W08D2.1|reactome:R-CEL-3238698|ensemblmetazoa:W08D2.1.1(transcript)|ensemblmetazoa:WBGene00001188(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1905484"(negative regulation of motor neuron migration)|go:"GO:1905485"(positive regulation of motor neuron migration)|go:"GO:1905488"(positive regulation of anterior/posterior axon guidance)|go:"GO:1905491"(positive regulation of sensory neuron axon guidance) ensemblmetazoa:C01G6.8a.1(transcript)|ensemblmetazoa:WBGene00000289(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1904937"(sensory neuron migration)|refseq:NP_001021908.1|refseq:NP_001033327.1|uniprotkb:Q9BLY1(uniprot-removed-ac)|interpro:IPR003599(Immunoglobulin subtype)|wormbase:C01G6.8b|wormbase:C01G6.8c|wormbase:C01G6.8a|interpro:IPR000001(Kringle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016247(Tyrosine-protein kinase transmembrane receptor ROR)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018056|interpro:IPR020067|interpro:IPR020635|refseq:NP_001021907.1|reactome:R-CEL-5140745|interpro:IPR038178|interpro:IPR036179|interpro:IPR036790|interpro:IPR041775 - - - figure legend:Fig. 2. CAM-1 CRD binds Wnts CWN-1, EGL-20 and MOM-2.|caution:Exact coordinates of the FZ domain was not given in the paper so has been inferred from the UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/29 2014/10/16 rogid:aIaPBdKP2K6MMONua/3gNi2QL7c6239 rogid:74YAW64NJn6oIRrT/wIBS0F+XJU6239 intact-crc:6DA3B97605A08CE0|rigid:TZJCgD+FgQkBpYjLLZYKxKBQ3M0 false ha tag:?-? alkaline phosphatase tag:?-?|necessary binding region:354..354-429..429(IPR020067) - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:G5EGK5 uniprotkb:P34888 intact:EBI-2930565|ensemblmetazoa:C01G6.8a.1|uniprotkb:G5ECA5|uniprotkb:Q38G54 intact:EBI-330642|ensemblmetazoa:K10B4.6a.1 psi-mi:cam1_caeel(display_long)|uniprotkb:cam-1(gene name)|psi-mi:cam-1(display_short)|uniprotkb:kin-8(gene name synonym)|uniprotkb:C01G6.8(orf name) psi-mi:wnt1_caeel(display_long)|uniprotkb:K10B4.6(orf name)|uniprotkb:cwn-1(gene name)|psi-mi:cwn-1(display_short)|uniprotkb:wnt-1(gene name synonym) psi-mi:"MI:0400"(affinity technology) Green et al. (2007) pubmed:17942487|imex:IM-20520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930632|imex:IM-20520-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C01G6.8a.1(transcript)|ensemblmetazoa:WBGene00000289(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1904937"(sensory neuron migration)|refseq:NP_001021908.1|refseq:NP_001033327.1|uniprotkb:Q9BLY1(uniprot-removed-ac)|interpro:IPR003599(Immunoglobulin subtype)|wormbase:C01G6.8b|wormbase:C01G6.8c|wormbase:C01G6.8a|interpro:IPR000001(Kringle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016247(Tyrosine-protein kinase transmembrane receptor ROR)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018056|interpro:IPR020067|interpro:IPR020635|refseq:NP_001021907.1|reactome:R-CEL-5140745|interpro:IPR038178|interpro:IPR036179|interpro:IPR036790|interpro:IPR041775 refseq:NP_493668.1|wormbase:K10B4.6a|dip:DIP-24702N|ensemblmetazoa:K10B4.6a.1(transcript)|ensemblmetazoa:WBGene00000857(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1905485"(positive regulation of motor neuron migration)|go:"GO:1905488"(positive regulation of anterior/posterior axon guidance)|go:"GO:1905491"(positive regulation of sensory neuron axon guidance)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-CEL-3238698|reactome:R-CEL-4086400 - - - figure legend:Fig. 2. CAM-1 CRD binds Wnts CWN-1, EGL-20 and MOM-2.|caution:Exact coordinates of the FZ domain not given in the paper so have been inferred from the UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/29 2014/10/16 rogid:74YAW64NJn6oIRrT/wIBS0F+XJU6239 rogid:aiCSE69DZ3g1aMJQDofuE8OrM886239 intact-crc:7AE83A15A6615F14|rigid:In/e7f8aO0RYw4lVXimixPEdVMI false alkaline phosphatase tag:?-?|necessary binding region:354..354-429..429(IPR020067) ha tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q10459 uniprotkb:G5EGK5 intact:EBI-321425|uniprotkb:O16146|ensemblmetazoa:F38E1.7.1|ensemblmetazoa:F38E1.7.2 intact:EBI-2930565|ensemblmetazoa:C01G6.8a.1|uniprotkb:G5ECA5|uniprotkb:Q38G54 psi-mi:mom2_caeel(display_long)|uniprotkb:mom-2(gene name)|psi-mi:mom-2(display_short)|uniprotkb:F38E1.7(orf name) psi-mi:cam1_caeel(display_long)|uniprotkb:cam-1(gene name)|psi-mi:cam-1(display_short)|uniprotkb:kin-8(gene name synonym)|uniprotkb:C01G6.8(orf name) psi-mi:"MI:0400"(affinity technology) Green et al. (2007) pubmed:17942487|imex:IM-20520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930649|imex:IM-20520-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505154.1|wormbase:F38E1.7|ensemblmetazoa:F38E1.7.1(transcript)|ensemblmetazoa:F38E1.7.2(transcript)|ensemblmetazoa:WBGene00003395(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1905485"(positive regulation of motor neuron migration)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|dip:DIP-26433N|reactome:R-CEL-3238698|reactome:R-CEL-4086398|reactome:R-CEL-4086400 ensemblmetazoa:C01G6.8a.1(transcript)|ensemblmetazoa:WBGene00000289(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097475"(motor neuron migration)|go:"GO:1904936"(interneuron migration)|go:"GO:1904937"(sensory neuron migration)|refseq:NP_001021908.1|refseq:NP_001033327.1|uniprotkb:Q9BLY1(uniprot-removed-ac)|interpro:IPR003599(Immunoglobulin subtype)|wormbase:C01G6.8b|wormbase:C01G6.8c|wormbase:C01G6.8a|interpro:IPR000001(Kringle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016247(Tyrosine-protein kinase transmembrane receptor ROR)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018056|interpro:IPR020067|interpro:IPR020635|refseq:NP_001021907.1|reactome:R-CEL-5140745|interpro:IPR038178|interpro:IPR036179|interpro:IPR036790|interpro:IPR041775 - - - figure legend:Fig. 2. CAM-1 CRD binds Wnts CWN-1, EGL-20 and MOM-2.|caution:Exact coordinates of the FZ domain not given in the paper so has been inferred from the InterPro entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/29 2014/10/16 rogid:/Aa9byYtB2KebSCVzT2W3tqAwqU6239 rogid:74YAW64NJn6oIRrT/wIBS0F+XJU6239 intact-crc:A7CD8441661CDA5F|rigid:fAW7fovwy4O0Q41oaCvyevkzpxk false ha tag:?-? alkaline phosphatase tag:?-?|necessary binding region:354..354-429..429(IPR020067) - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)