#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40338 uniprotkb:Q61771 intact:EBI-2659335|ensembl:ENSMUSP00000039418 intact:EBI-6395332|ensembl:ENSMUSP00000028977|uniprotkb:Q3UFZ8|uniprotkb:Q8BNH4 psi-mi:vhl_mouse(display_long)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Vhlh(gene name synonym)|uniprotkb:Vhl(gene name)|psi-mi:Vhl(display_short) psi-mi:kif3b_mouse(display_long)|uniprotkb:Kif3b(gene name)|psi-mi:Kif3b(display_short)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599695|mint:MINT-8078009|imex:IM-11631-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033533.1|go:"GO:0042069"(regulation of catecholamine metabolic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048069"(eye pigmentation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048877"(homeostasis of number of retina cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1903827"|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|rcsb pdb:1HV2|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|reactome:R-MMU-1234176|reactome:R-MMU-3232142|reactome:R-MMU-8951664|reactome:R-MMU-9706019|reactome:R-MMU-983168|ensembl:ENSMUSG00000033933(gene)|ensembl:ENSMUST00000035673(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030891"(VCB complex)|mint:MINT-8078011(identity) ensembl:ENSMUSG00000027475(gene)|ensembl:ENSMUST00000028977(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_032470.3|mint:MINT-8078013(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:UCMuvSG9JUKZ3zXzZPgiNpnYRB810090 rogid:JsWP3UOgu6c3iZWc6pr3aU+hNrs10090 intact-crc:4FFCC5F3886582A7|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40338 uniprotkb:P28741 intact:EBI-2659335|ensembl:ENSMUSP00000039418 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 psi-mi:vhl_mouse(display_long)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Vhlh(gene name synonym)|uniprotkb:Vhl(gene name)|psi-mi:Vhl(display_short) psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599695|mint:MINT-8078009|imex:IM-11631-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033533.1|go:"GO:0042069"(regulation of catecholamine metabolic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048069"(eye pigmentation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048877"(homeostasis of number of retina cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1903827"|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|rcsb pdb:1HV2|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|reactome:R-MMU-1234176|reactome:R-MMU-3232142|reactome:R-MMU-8951664|reactome:R-MMU-9706019|reactome:R-MMU-983168|ensembl:ENSMUSG00000033933(gene)|ensembl:ENSMUST00000035673(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030891"(VCB complex)|mint:MINT-8078011(identity) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N|mint:MINT-8078015(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:UCMuvSG9JUKZ3zXzZPgiNpnYRB810090 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 intact-crc:4FFCC5F3886582A7|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40338 uniprotkb:P70188 intact:EBI-2659335|ensembl:ENSMUSP00000039418 intact:EBI-6169443|ensembl:ENSMUSP00000027877|uniprotkb:P70189|uniprotkb:Q6GTS3 psi-mi:vhl_mouse(display_long)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Vhlh(gene name synonym)|uniprotkb:Vhl(gene name)|psi-mi:Vhl(display_short) psi-mi:kifa3_mouse(display_long)|uniprotkb:Kifap3(gene name)|psi-mi:Kifap3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599695|mint:MINT-8078009|imex:IM-11631-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033533.1|go:"GO:0042069"(regulation of catecholamine metabolic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048069"(eye pigmentation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048877"(homeostasis of number of retina cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1903827"|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|rcsb pdb:1HV2|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|reactome:R-MMU-1234176|reactome:R-MMU-3232142|reactome:R-MMU-8951664|reactome:R-MMU-9706019|reactome:R-MMU-983168|ensembl:ENSMUSG00000033933(gene)|ensembl:ENSMUST00000035673(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030891"(VCB complex)|mint:MINT-8078011(identity) interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000026585(gene)|ensembl:ENSMUST00000027877(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_001292572.1|refseq:NP_034759.1|mint:MINT-8078012(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:UCMuvSG9JUKZ3zXzZPgiNpnYRB810090 rogid:ZPQUT3r4ZkEieMyTWZeER0I4g+c10090 intact-crc:4FFCC5F3886582A7|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28741 uniprotkb:Q61771 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 intact:EBI-6395332|ensembl:ENSMUSP00000028977|uniprotkb:Q3UFZ8|uniprotkb:Q8BNH4 psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:kif3b_mouse(display_long)|uniprotkb:Kif3b(gene name)|psi-mi:Kif3b(display_short)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599729|mint:MINT-8078028|imex:IM-11631-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N|mint:MINT-8078036(identity) ensembl:ENSMUSG00000027475(gene)|ensembl:ENSMUST00000028977(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_032470.3|mint:MINT-8078034(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rogid:JsWP3UOgu6c3iZWc6pr3aU+hNrs10090 intact-crc:6E0EE9E128683C71|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28741 uniprotkb:P70188 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 intact:EBI-6169443|ensembl:ENSMUSP00000027877|uniprotkb:P70189|uniprotkb:Q6GTS3 psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:kifa3_mouse(display_long)|uniprotkb:Kifap3(gene name)|psi-mi:Kifap3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599729|mint:MINT-8078028|imex:IM-11631-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N|mint:MINT-8078036(identity) interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000026585(gene)|ensembl:ENSMUST00000027877(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_001292572.1|refseq:NP_034759.1|mint:MINT-8078032(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rogid:ZPQUT3r4ZkEieMyTWZeER0I4g+c10090 intact-crc:6E0EE9E128683C71|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28741 uniprotkb:P40338 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 intact:EBI-2659335|ensembl:ENSMUSP00000039418 psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:vhl_mouse(display_long)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Vhlh(gene name synonym)|uniprotkb:Vhl(gene name)|psi-mi:Vhl(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7599729|mint:MINT-8078028|imex:IM-11631-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N|mint:MINT-8078036(identity) refseq:NP_033533.1|go:"GO:0042069"(regulation of catecholamine metabolic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048069"(eye pigmentation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048877"(homeostasis of number of retina cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1903827"|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|rcsb pdb:1HV2|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|reactome:R-MMU-1234176|reactome:R-MMU-3232142|reactome:R-MMU-8951664|reactome:R-MMU-9706019|reactome:R-MMU-983168|ensembl:ENSMUSG00000033933(gene)|ensembl:ENSMUST00000035673(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030891"(VCB complex)|mint:MINT-8078030(identity) - - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-kidney)|taxid:10090(Mus musculus) - 2010/12/07 2014/10/16 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rogid:UCMuvSG9JUKZ3zXzZPgiNpnYRB810090 intact-crc:6E0EE9E128683C71|rigid:jGthXw7H0LdMSI2umiExkBaEiHs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28741 uniprotkb:P40337 intact:EBI-6169413|ensembl:ENSMUSP00000112782|uniprotkb:Q7TSZ7 intact:EBI-301246|uniprotkb:Q13599|uniprotkb:B2RE45|uniprotkb:Q6PDA9|ensembl:ENSP00000256474 psi-mi:kif3a_mouse(display_long)|uniprotkb:Kif3a(gene name)|psi-mi:Kif3a(display_short)|uniprotkb:Kif3(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3A(gene name synonym) psi-mi:vhl_human(display_long)|uniprotkb:VHL(gene name)|psi-mi:VHL(display_short)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Protein G7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599756|mint:MINT-8078048|imex:IM-11631-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018395(gene)|ensembl:ENSMUST00000120613(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003341"(cilium movement)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008544"(epidermis development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030507"(spectrin binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0036334"(epidermal stem cell homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905128"(positive regulation of axo-dendritic protein transport)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990939"|go:"GO:2000771"(positive regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P28741|rcsb pdb:5JVR|rcsb pdb:5JX1|reactome:R-MMU-2132295|reactome:R-MMU-5610787|reactome:R-MMU-5620924|reactome:R-MMU-5635838|reactome:R-MMU-983189|reactome:R-MMU-6811434|refseq:NP_001277734.1|refseq:NP_001277735.1|refseq:NP_032469.2|dip:DIP-46318N|mint:MINT-8078051(identity) rcsb pdb:6BVB|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:4W9I|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:4W9J|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:4W9K|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6SIS|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-1234176|reactome:R-HSA-3232142|rcsb pdb:4W9L|reactome:R-HSA-8951664|rcsb pdb:4WQO|reactome:R-HSA-9682706|reactome:R-HSA-9694686|reactome:R-HSA-9706019|reactome:R-HSA-983168|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|ensembl:ENSG00000134086(gene)|ensembl:ENST00000256474(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050821"(protein stabilization)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|mint:P40337|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|refseq:NP_000542.1|refseq:NP_937799.1|dip:DIP-32585N|mint:MINT-8078050(identity) - - - figure legend:f2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c26)|taxid:10090(Mouse Colon26 adenocarcinoma cell line) - 2010/12/07 2014/10/16 rogid:3P8b4UgzwNTTXf1KVCB6+T+1+bk10090 rogid:KaCKDTSj0xPG9YmfFsXIbkRt3A89606 intact-crc:5A88406688BD3A43|rigid:wn3d6MeBhyRj+4zoInIWWkcwfCg false - binding-associated region:54-213(MINT-8078054) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70188 uniprotkb:P40337 intact:EBI-6169443|ensembl:ENSMUSP00000027877|uniprotkb:P70189|uniprotkb:Q6GTS3 intact:EBI-301246|uniprotkb:Q13599|uniprotkb:B2RE45|uniprotkb:Q6PDA9|ensembl:ENSP00000256474 psi-mi:kifa3_mouse(display_long)|uniprotkb:Kifap3(gene name)|psi-mi:Kifap3(display_short) psi-mi:vhl_human(display_long)|uniprotkb:VHL(gene name)|psi-mi:VHL(display_short)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Protein G7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lolkema et al. (2007) doi:10.1016/j.febslet.2007.08.050|pubmed:17825299|imex:IM-11631|mint:MINT-6803815 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599788|mint:MINT-8078059|imex:IM-11631-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-2132295|reactome:R-MMU-5620924|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000026585(gene)|ensembl:ENSMUST00000027877(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_001292572.1|refseq:NP_034759.1|mint:MINT-8078062(identity) rcsb pdb:6BVB|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:4W9I|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:4W9J|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:4W9K|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6SIS|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-1234176|reactome:R-HSA-3232142|rcsb pdb:4W9L|reactome:R-HSA-8951664|rcsb pdb:4WQO|reactome:R-HSA-9682706|reactome:R-HSA-9694686|reactome:R-HSA-9706019|reactome:R-HSA-983168|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|ensembl:ENSG00000134086(gene)|ensembl:ENST00000256474(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050821"(protein stabilization)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|mint:P40337|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|refseq:NP_000542.1|refseq:NP_937799.1|dip:DIP-32585N|mint:MINT-8078061(identity) - - - figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c26)|taxid:10090(Mouse Colon26 adenocarcinoma cell line) - 2010/12/07 2014/10/16 rogid:ZPQUT3r4ZkEieMyTWZeER0I4g+c10090 rogid:KaCKDTSj0xPG9YmfFsXIbkRt3A89606 intact-crc:9D4422A6F9A24D18|rigid:i3BOlt37vaUQcMc1X6/ZHRlcpnQ false - binding-associated region:124-213,1-94(MINT-8078065) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)