#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0CW72 uniprotkb:P0CW72 intact:EBI-2620133|uniprotkb:Q777A5 intact:EBI-2620133|uniprotkb:Q777A5 psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620961|imex:IM-20435-3 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 intact-crc:5EDC4A24E552A1A6|rigid:IJXWRACeU0AGOb92cIKCYy/XDVI false sufficient binding region:?-? sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C704 uniprotkb:P14348 intact:EBI-2620975|uniprotkb:Q3KSQ5 intact:EBI-2620158|intact:EBI-9645437|uniprotkb:Q777G5 psi-mi:mcp_ebvg(display_long)|uniprotkb:MCP(gene name)|psi-mi:MCP(display_short)|uniprotkb:BcLF1(orf name) psi-mi:scp_ebvb9(display_long)|uniprotkb:SCP(gene name)|psi-mi:SCP(display_short)|uniprotkb:BFRF3(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620972|imex:IM-20435-4 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000912("Herpesvirus major capsid protein (MCP)")|interpro:IPR023233|go:"GO:0005198"(structural molecule activity)|go:"GO:0039622"(T=16 icosahedral viral capsid)|go:"GO:0042025"(host cell nucleus) refseq:YP_401651.1|interpro:IPR009299(Gammaherpesvirus capsid)|go:"GO:0016032"(viral process)|go:"GO:0019028"(viral capsid)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:7BQX|rcsb pdb:7BR7|rcsb pdb:7BR8|rcsb pdb:7BSI|rcsb pdb:6W19|rcsb pdb:6W2D|rcsb pdb:6W2E - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:pOprVAaLw3srjW8dcPHTMXO2t3E10376 rogid:dBnWcMYacSnhXaIHq5VNw+H4cvg10377 intact-crc:74F881CE708E73D6|rigid:su1fjhROM9w9lqhFrUFwNGAjNJM false sufficient binding region:1-1381 sufficient binding region:1-176 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03185 uniprotkb:P0CK47 intact:EBI-2620196|uniprotkb:Q777G7 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620988|imex:IM-20435-5 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:0C31651CD6FA8191|rigid:riFMRw8yWUcOAqiOGqFvTM/y25o false sufficient binding region:1-315 sufficient binding region:1-318 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C731 uniprotkb:Q3KSQ2 intact:EBI-2621032 intact:EBI-2621028 psi-mi:kr2_ebvg(display_long)|uniprotkb:BGLF4(orf name) psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621035|imex:IM-20435-8 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|refseq:YP_401688.1|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10376 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 intact-crc:DF35D0346A961DDD|rigid:M088Pmvsev+TxWgpDfjWV7EwsX8 false sufficient binding region:?-? sufficient binding region:1-607 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CK53 uniprotkb:A0A0C7TRZ7 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 intact:EBI-2621017|uniprotkb:Q1HVH1 psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:a0a0c7trz7_ebvg(display_long)|uniprotkb:BSLF1(gene name)|psi-mi:BSLF1(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621014|imex:IM-20435-7 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 interpro:IPR033685|go:"GO:0003896"(DNA primase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2017/03/31 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 rogid:llx/R8yUK2gVl3XbbCH1k6ya6yI10376 intact-crc:2D63FD809D14DE45|rigid:AboS0HCj37dK8S175klotNQcB9s false sufficient binding region:1-336 sufficient binding region:571-874 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CK47 uniprotkb:P03185 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2620196|uniprotkb:Q777G7 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620999|imex:IM-20435-6 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 intact-crc:ABF45DBB3126DA95|rigid:riFMRw8yWUcOAqiOGqFvTM/y25o false sufficient binding region:1-318 sufficient binding region:1-315 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST5 uniprotkb:Q66542 intact:EBI-2621066 intact:EBI-2621061 psi-mi:blrf2_ebvg(display_long)|uniprotkb:BLRF2(orf name) psi-mi:q66542_ebvg(display_long)|uniprotkb:BNRF1(gene name)|psi-mi:BNRF1(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621069|imex:IM-20435-10 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008642(Herpesvirus BLRF2)|go:"GO:0003677"(DNA binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039503"(suppression by virus of host innate immune response) interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010077(Herpes virus tegument protein/v-FGAM-synthase)|interpro:IPR024346|go:"GO:0019033"(viral tegument)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR029062|interpro:IPR036676|interpro:IPR036921 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:MDNV843jvGJDWdb7mgPXsM/iRAI10376 rogid:Icr9yRMWuFQlx5cIey5tdAhtKvo10376 intact-crc:87E05C209AD786A5|rigid:LaNoYPn3wjqKvlTZ5kPl4GHSa90 false sufficient binding region:1-162 sufficient binding region:1-1318 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSS4 uniprotkb:Q3KSS4 intact:EBI-2621046 intact:EBI-2621046 psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621050|imex:IM-20435-9 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:51575292A3E864C0|rigid:ybhMttsn7uuRkz+kR1VVxFKjEtU false sufficient binding region:387-641 sufficient binding region:387-641 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03209 uniprotkb:Q3KSP5 intact:EBI-2621080|uniprotkb:Q777E4 intact:EBI-2621084 psi-mi:rta_ebvb9(display_long)|uniprotkb:Immediate-early protein Rta(gene name synonym)|uniprotkb:BRLF1(orf name) psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621088|imex:IM-20435-11 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401674.1|interpro:IPR004998(Herpesvirus transcription activation factor)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0050434"(positive regulation of viral transcription) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9lTewHV10YH3Xy5vErhGn/eyEz010377 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 intact-crc:AA0FA0A8F3CE4AD1|rigid:aSf/eH0q3We186gRSQ0R1N3QrZs false sufficient binding region:1-605 sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSP5 uniprotkb:Q3KSP5 intact:EBI-2621084 intact:EBI-2621084 psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621099|imex:IM-20435-12 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 intact-crc:F48C1FBAC3095AB0|rigid:zTBix1gJNpb3B9hQ2c8tgWbUSos false sufficient binding region:?-? sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CW72 uniprotkb:Q3KSU8 intact:EBI-2620133|uniprotkb:Q777A5 intact:EBI-2621128 psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621125|imex:IM-20435-14 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:511064F01D394383|rigid:oIQQuvvkEMTy3Z9ARITse8+XbX8 false sufficient binding region:?-? sufficient binding region:1-1000 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSU1 uniprotkb:Q3KSU1 intact:EBI-2621113|uniprotkb:Q3KSU0 intact:EBI-2621113|uniprotkb:Q3KSU0 psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621110|imex:IM-20435-13 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 intact-crc:A74171A5F9BA646D|rigid:d7o1I1HwZoA2Wt6her+2jpJhytM false sufficient binding region:42-479 sufficient binding region:42-479 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSV2 uniprotkb:P03206 intact:EBI-633374 intact:EBI-2621186|uniprotkb:Q69127|uniprotkb:Q777E5 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:bzlf1_ebvb9(display_long)|uniprotkb:Zebra(gene name synonym)|uniprotkb:BZLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621183|imex:IM-20435-18 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) rcsb pdb:5SZX|refseq:YP_401673.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR017339(Trans-activator protein BZLF1, human herpesvirus 4)|rcsb pdb:1ZSD|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2C9L|rcsb pdb:2C9N|rcsb pdb:3KWW|rcsb pdb:3KXF|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3SPV|rcsb pdb:2NX5 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:bkOXtFgnAd5I7kRzo9QRpEPmKTw10377 intact-crc:69E6BBFBFF37111C|rigid:+N6WI4/2hEUVx9K08FrecaCMGeI false sufficient binding region:59-448 sufficient binding region:1-167 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST2 uniprotkb:Q3KSV2 intact:EBI-2621171 intact:EBI-633374 psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621168|imex:IM-20435-17 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 intact-crc:6C55C0C14FE16F4C|rigid:/HhpqRngzISi5IoSvotjwssvehE false sufficient binding region:601-900 sufficient binding region:59-448 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSU8 uniprotkb:Q3KSU8 intact:EBI-2621128 intact:EBI-2621128 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621142|imex:IM-20435-15 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:4DB91DBE4FC32253|rigid:Fgwa1Dqw3oIPyZ7Q4eZEXw0/oeA false sufficient binding region:1501-2500 sufficient binding region:1001-2000 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSV2 uniprotkb:P03225 intact:EBI-633374 intact:EBI-2621153|uniprotkb:Q777C4 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621157|imex:IM-20435-16 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 intact-crc:98C295CBAC090650|rigid:K5Yh4eWBhpMA+hDG95oodgNf60Y false sufficient binding region:59-448 sufficient binding region:208-420 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSU5 uniprotkb:P0C704 intact:EBI-2621212 intact:EBI-2620975|uniprotkb:Q3KSQ5 psi-mi:rir1_ebvg(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:BORF2(orf name) psi-mi:mcp_ebvg(display_long)|uniprotkb:MCP(gene name)|psi-mi:MCP(display_short)|uniprotkb:BcLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621209|imex:IM-20435-20 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039718|interpro:IPR034717|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency) interpro:IPR000912("Herpesvirus major capsid protein (MCP)")|interpro:IPR023233|go:"GO:0005198"(structural molecule activity)|go:"GO:0039622"(T=16 icosahedral viral capsid)|go:"GO:0042025"(host cell nucleus) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:VBXxgDZ24E0tHkx2uebB+/WJybI10376 rogid:pOprVAaLw3srjW8dcPHTMXO2t3E10376 intact-crc:6FF79488412F32DD|rigid:mXewigtkWSrkfjD/CDS8O9upAVY false sufficient binding region:1-826 sufficient binding region:660-1381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST2 uniprotkb:Q3KST2 intact:EBI-2621171 intact:EBI-2621171 psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621198|imex:IM-20435-19 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 intact-crc:CB519FD7F1774B05|rigid:A37NjWvqQ3O6iPvWMQtyt1Z5D5Q false sufficient binding region:601-900 sufficient binding region:451-750 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C729 uniprotkb:Q3KSS5 intact:EBI-2621229 intact:EBI-2621226 psi-mi:lmp2_ebvg(display_long)|uniprotkb:Terminal protein(gene name synonym)|uniprotkb:LMP2(gene name)|psi-mi:LMP2(display_short) psi-mi:brrf2_ebvg(display_long)|uniprotkb:BRRF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621223|imex:IM-20435-21 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010881(Gammaherpesvirus latent membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019042"(viral latency) interpro:IPR008550(Protein of unknown function DUF832, gammaherpesvirus)|go:"GO:0019033"(viral tegument) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Gld4/oda4Ub+/x4OO1LviqFMZmw10376 rogid:kkGaP5sJ+ZUfK3LlaYYsVNsh/zs10376 intact-crc:ADC05FA1A45434A7|rigid:Ag5Buqb2QOqr+f5u44fRKSzRZI4 false sufficient binding region:1-119 sufficient binding region:1-537 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST2 uniprotkb:Q69119 intact:EBI-2621171 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:q69119_ebvg(display_long) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621241|imex:IM-20435-22 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 intact-crc:93E9790C8DC4DEEE|rigid:T62fMuXSu1ACxlvPs242XPkLnug false sufficient binding region:451-750 sufficient binding region:601-900 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST0 uniprotkb:Q3KSQ2 intact:EBI-2621257 intact:EBI-2621028 psi-mi:ebna6_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3C(gene name synonym)|uniprotkb:Epstein-Barr nuclear antigen 4B(gene name synonym)|uniprotkb:BERF3-BERF4(orf name)|uniprotkb:EBNA6(gene name)|psi-mi:EBNA6(display_short) psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621262|imex:IM-20435-23 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0019042"(viral latency)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0044204"(host cell nuclear matrix) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:L8oAKgomHAQsodYgDeoa0HUzf9A10376 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 intact-crc:F792CBB4E8673742|rigid:0XMeEwFcZTE4wpfbomzmaJpJ3z0 false sufficient binding region:751-992 sufficient binding region:391-607 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSU5 uniprotkb:P0CK58 intact:EBI-2621212 intact:EBI-2621293|uniprotkb:P03229|uniprotkb:Q777A6 psi-mi:rir1_ebvg(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:BORF2(orf name) psi-mi:balf1_ebvb9(display_long)|uniprotkb:BALF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621297|imex:IM-20435-25 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039718|interpro:IPR034717|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency) refseq:YP_401718.2|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR010677(BALF1) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:VBXxgDZ24E0tHkx2uebB+/WJybI10376 rogid:ZFg3TCa2ZO9XTXB9UJ9DdRJYzhI10377 intact-crc:26D24777E285B9D4|rigid:kDXH1tYCmso0pM5f3ZTayyxlIOw false sufficient binding region:1-826 sufficient binding region:144-220 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03208 uniprotkb:Q3KSQ2 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-2621028 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621308|imex:IM-20435-26 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 intact-crc:A4433000DBADD44B|rigid:8DDhiQo78NTRdmVDFaYJIcynxp0 false sufficient binding region:1-312 sufficient binding region:1-400 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSQ2 uniprotkb:P03209 intact:EBI-2621028 intact:EBI-2621080|uniprotkb:Q777E4 psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:rta_ebvb9(display_long)|uniprotkb:Immediate-early protein Rta(gene name synonym)|uniprotkb:BRLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621323|imex:IM-20435-27 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 refseq:YP_401674.1|interpro:IPR004998(Herpesvirus transcription activation factor)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0050434"(positive regulation of viral transcription) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 rogid:9lTewHV10YH3Xy5vErhGn/eyEz010377 intact-crc:A13C93717CCF06EF|rigid:No9J6htV3Yh3gJngTqlVFEhTQHk false sufficient binding region:201-607 sufficient binding region:1-605 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q69131 uniprotkb:P0C738 intact:EBI-2621273 intact:EBI-2621277|uniprotkb:Q8AZJ2|uniprotkb:Q04361 psi-mi:q69131_ebvg(display_long)|uniprotkb:BN-LF2a(gene name)|psi-mi:BN-LF2a(display_short)|uniprotkb:BNLF2a(gene name synonym) psi-mi:bnl2a_ebvg(display_long)|uniprotkb:BNLF2a(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621282|imex:IM-20435-24 author score:+ - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane) refseq:YP_401721.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:VVqfC7fMgq1PbzDHmtvLrE8+YRo10376 rogid:uKpc0Xg4Tut1Ks9Z0R3cQup0YVU10376 intact-crc:EA067D5386DBB86A|rigid:27G1VAySg4CdVzKiVs/O/l3Y7pk false sufficient binding region:1-60 sufficient binding region:1-60 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C701 uniprotkb:Q66542 intact:EBI-2621366|uniprotkb:Q777G0 intact:EBI-2621061 psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:q66542_ebvg(display_long)|uniprotkb:BNRF1(gene name)|psi-mi:BNRF1(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621370|imex:IM-20435-30 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010077(Herpes virus tegument protein/v-FGAM-synthase)|interpro:IPR024346|go:"GO:0019033"(viral tegument)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR029062|interpro:IPR036676|interpro:IPR036921 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 rogid:Icr9yRMWuFQlx5cIey5tdAhtKvo10376 intact-crc:29E52FF02DB006C4|rigid:i0VaiM3G8CughnfGhH7l0haLhqg false sufficient binding region:171-302 sufficient binding region:1-667 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CK58 uniprotkb:Q1HVC7 intact:EBI-2621293|uniprotkb:P03229|uniprotkb:Q777A6 intact:EBI-2621352|uniprotkb:Q1HVC6 psi-mi:balf1_ebvb9(display_long)|uniprotkb:BALF1(orf name) psi-mi:scaf_ebva8(display_long)|uniprotkb:Capsid protein P40(gene name synonym)|uniprotkb:Protease precursor(gene name synonym)|uniprotkb:Protein EC-RF3/EC-RF3A(gene name synonym)|uniprotkb:Virion structural protein BVRF2(gene name synonym)|uniprotkb:BVRF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621355|imex:IM-20435-29 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401718.2|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR010677(BALF1) interpro:IPR001847(Peptidase S21, herpesvirus maturational proteinase, assemblin)|refseq:YP_001129501.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039708"(nuclear capsid assembly)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR035443 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2015/12/04 rogid:ZFg3TCa2ZO9XTXB9UJ9DdRJYzhI10377 rogid:Je8NqD4CdcoBK/aR7GXhg4IfYSA82830 intact-crc:C13F6B27864E1FEA|rigid:t0HIc2Ka+IugTNyb13O3fgKQgUo false sufficient binding region:1-220 sufficient binding region:261-605 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CK49 uniprotkb:Q3KSR9 intact:EBI-2621334|uniprotkb:P03194|uniprotkb:Q777F4 intact:EBI-2621338 psi-mi:teg7_ebvb9(display_long)|uniprotkb:BSRF1(orf name) psi-mi:portl_ebvg(display_long)|uniprotkb:BBRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621341|imex:IM-20435-28 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019033"(viral tegument)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR007619(Herpesvirus U44 protein)|refseq:YP_401663.1 interpro:IPR002660(Herpesvirus UL6 like)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0006323"(DNA packaging)|rcsb pdb:6RVR|rcsb pdb:6RVS - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:p/kr3n9JhzCzMyGI4GxbU8uKkz010377 rogid:bizcWqCEC5rKsvJCV48jHmlbdAg10376 intact-crc:D81B7FAB2EADEBC9|rigid:mOe/vxzylbufs9qnUt9HAwEFgvg false sufficient binding region:1-218 sufficient binding region:1-613 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C734 uniprotkb:P0C6Z5 intact:EBI-2621388 intact:EBI-2621381|uniprotkb:Q777E6 psi-mi:btrf1_ebvg(display_long)|uniprotkb:BTRF1(orf name) psi-mi:gp42_ebvg(display_long)|uniprotkb:BZLF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621385|imex:IM-20435-31 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006772(Herpesvirus BTRF1 protein) interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|refseq:YP_401672.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0055036"(virion membrane)|rcsb pdb:5T1D|rcsb pdb:6C5V - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:JMhrq+6M63yNNbXMEasFG2Z0jwg10376 rogid:G0vgvTJ19nuF/gXajIeCo1AoTVw10376 intact-crc:471750A4D5D8D2D2|rigid:lyt0wnxewUJCyR22Rx/RBzRpSnA false sufficient binding region:?-? sufficient binding region:30-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSS3 uniprotkb:A8CSJ8 intact:EBI-2621403 intact:EBI-2621399 psi-mi:gl_ebvg(display_long)|uniprotkb:gL(gene name)|psi-mi:gL(display_short)|uniprotkb:BKRF2(orf name) psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621407|imex:IM-20435-32 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034708|interpro:IPR020175|go:"GO:0016020"(membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|interpro:IPR038313 interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:7zAlPU2ael0kGkn7vBOoPvR2+n810376 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 intact-crc:88A399A54338F076|rigid:CaU4Vcgxi8QoY0XWfNC2STBQv90 false sufficient binding region:1-137 sufficient binding region:129-386 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68343 uniprotkb:P0CK51 intact:EBI-2621429|uniprotkb:Q1HVG6|uniprotkb:Q07284 intact:EBI-2621435|uniprotkb:P03216|uniprotkb:Q777D3 psi-mi:gp350_ebva8(display_long)|uniprotkb:Membrane antigen(gene name synonym)|uniprotkb:BLLF1(orf name) psi-mi:cep3_ebvb9(display_long)|uniprotkb:BBLF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621432|imex:IM-20435-34 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129462.1|interpro:IPR007796(Herpes virus major outer envelope glycoprotein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0055036"(virion membrane) go:"GO:0016020"(membrane)|go:"GO:0019033"(viral tegument)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR024360|refseq:YP_401686.1 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:UpRI96UTLxnxw7AG/GVTTdMC7Uc82830 rogid:0YzxqkFkiaWwuQh0sQ65ypcP0js10377 intact-crc:4AE738FA8067BCB2|rigid:VfX5PfavtO6UU9x2zxqLUWuABFQ false sufficient binding region:?-? sufficient binding region:1-75 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03199 uniprotkb:Q69139 intact:EBI-2621452|uniprotkb:Q777E9 intact:EBI-2621446 psi-mi:bllf2_ebvb9(display_long)|uniprotkb:BLLF2(orf name) psi-mi:q69139_ebvg(display_long) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621449|imex:IM-20435-35 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401668.1|interpro:IPR035221 go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:PUFD1dey0nvc0ea8sABBzbDVTyE10377 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 intact-crc:53186BF260FABE52|rigid:J/tKkcLBxfoJNLp9UZ6gQrnux84 false sufficient binding region:1-148 sufficient binding region:451-750 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03208 uniprotkb:Q3KSS4 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-2621046 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621418|imex:IM-20435-33 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:F09B0D41F98C53C3|rigid:OBooLnABlbvSLVNjTstaPlkXlmw false sufficient binding region:54-312 sufficient binding region:1-89 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C6Z4 uniprotkb:A8CSJ8 intact:EBI-2621475|uniprotkb:Q777F2 intact:EBI-2621399 psi-mi:gn_ebvg(display_long)|uniprotkb:gN(gene name)|psi-mi:gN(display_short)|uniprotkb:BLRF1(orf name) psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621480|imex:IM-20435-37 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034707|refseq:YP_401665.1|interpro:IPR005211(UL73 viral envelope glycoprotein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0033644"(host cell membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane) interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:/r0ZmPet0XVtnS8IW92K3K2cB0k10376 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 intact-crc:ACE0655DFFD4D3FF|rigid:kJwAyJV90AwCgYiUX+kWrECWWVQ false sufficient binding region:33-102 sufficient binding region:1-386 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CW72 uniprotkb:P0C6Z4 intact:EBI-2620133|uniprotkb:Q777A5 intact:EBI-2621475|uniprotkb:Q777F2 psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:gn_ebvg(display_long)|uniprotkb:gN(gene name)|psi-mi:gN(display_short)|uniprotkb:BLRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621491|imex:IM-20435-38 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N interpro:IPR034707|refseq:YP_401665.1|interpro:IPR005211(UL73 viral envelope glycoprotein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0033644"(host cell membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 rogid:/r0ZmPet0XVtnS8IW92K3K2cB0k10376 intact-crc:E00F562ABFD4A762|rigid:apP2berVASmg08kyqMC2yw6Xl9A false sufficient binding region:?-? sufficient binding region:33-102 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A8CSJ8 uniprotkb:P03199 intact:EBI-2621399 intact:EBI-2621452|uniprotkb:Q777E9 psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:bllf2_ebvb9(display_long)|uniprotkb:BLLF2(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621464|imex:IM-20435-36 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) refseq:YP_401668.1|interpro:IPR035221 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 rogid:PUFD1dey0nvc0ea8sABBzbDVTyE10377 intact-crc:D55E3AF6D2913C20|rigid:RzxFmHJB3hgpsWT3qcnTSxSBnWw false sufficient binding region:232-351 sufficient binding region:1-148 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KSU3 uniprotkb:Q69139 intact:EBI-2621528 intact:EBI-2621446 psi-mi:ead_ebvg(display_long)|uniprotkb:Early antigen protein D(gene name synonym)|uniprotkb:Polymerase accessory subunit(gene name synonym)|uniprotkb:BMRF1(orf name) psi-mi:q69139_ebvg(display_long) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621531|imex:IM-20435-41 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007013(DNA replication accessory factor, herpesviridae)|go:"GO:0003677"(DNA binding)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus) go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+2DS1WFv/gYB1GJZALDpyc6D4N010376 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 intact-crc:16EF57C27A891D3B|rigid:JlpIrwc55rJ1ip/hxXkGwph0qjw false sufficient binding region:1-404 sufficient binding region:451-750 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03208 uniprotkb:P03232 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-2621513|uniprotkb:Q777B8 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:ul24_ebvb9(display_long)|uniprotkb:BXRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621517|imex:IM-20435-40 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) refseq:YP_401702.1|interpro:IPR002580(Herpes virus protein UL24)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044196"(host cell nucleolus) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:WsCdJejq1HJmTw/CdzfUSVjRFKM10377 intact-crc:254071727FDB62E6|rigid:VVJromks4I4nMH1ePXnZpJSxFac false sufficient binding region:54-312 sufficient binding region:1-248 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03208 uniprotkb:P0CW72 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-2620133|uniprotkb:Q777A5 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621502|imex:IM-20435-39 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 intact-crc:BCD2DFCBF63D3E09|rigid:kW1CxZAaSVGRCJTHB5WdT8PycEs false sufficient binding region:1-312 sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KST1 uniprotkb:P0C762 intact:EBI-2621564 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:ebna4_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621568|imex:IM-20435-43 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:mYUoLw39RISWtVj3ADLS7vi8C/w10376 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:B4674F9C0FF03DFE|rigid:FbBy06puAoCRQSPtms05mystqlM false sufficient binding region:601-900 sufficient binding region:1-857 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C733 uniprotkb:Q1HVD6 intact:EBI-2621545 intact:EBI-2621542 psi-mi:bnl2b_ebvg(display_long)|uniprotkb:BNLF2b(orf name) psi-mi:q1hvd6_ebva8(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621548|imex:IM-20435-42 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:YP_001129492.1|interpro:IPR002690(Herpesvirus VP23-like capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:gd7Jl7VO2ho/65/ucdRbDv8GiGY10376 rogid:hMQYfBwXv5pPVOHgG+RuR0qrSLs82830 intact-crc:F9C5FA7E1FB2DD21|rigid:Tycbpfw6geo1NYNkVWyd1QrnQrA false sufficient binding region:?-? sufficient binding region:1-301 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q1HVD6 uniprotkb:Q3KST1 intact:EBI-2621542 intact:EBI-2621564 psi-mi:q1hvd6_ebva8(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short) psi-mi:ebna4_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621579|imex:IM-20435-44 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129492.1|interpro:IPR002690(Herpesvirus VP23-like capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:hMQYfBwXv5pPVOHgG+RuR0qrSLs82830 rogid:mYUoLw39RISWtVj3ADLS7vi8C/w10376 intact-crc:C4CBD13F4E6A1BA8|rigid:EU9bljDrOH5CGG3IHIDWembF82U false sufficient binding region:1-301 sufficient binding region:451-750 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q69119 uniprotkb:Q3KSS4 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 intact:EBI-2621046 psi-mi:q69119_ebvg(display_long) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621590|imex:IM-20435-45 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:1E6C282C3C9F92E9|rigid:mQGZ7UHHHkeCFCDaUinNuk3rmxA false sufficient binding region:601-900 sufficient binding region:1-89 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C704 uniprotkb:A8CSJ8 intact:EBI-2620975|uniprotkb:Q3KSQ5 intact:EBI-2621399 psi-mi:mcp_ebvg(display_long)|uniprotkb:MCP(gene name)|psi-mi:MCP(display_short)|uniprotkb:BcLF1(orf name) psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621601|imex:IM-20435-46 author score:- - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000912("Herpesvirus major capsid protein (MCP)")|interpro:IPR023233|go:"GO:0005198"(structural molecule activity)|go:"GO:0039622"(T=16 icosahedral viral capsid)|go:"GO:0042025"(host cell nucleus) interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:pOprVAaLw3srjW8dcPHTMXO2t3E10376 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 intact-crc:3599B41CA4A9EEC0|rigid:3OTbe0laObUSfBd74ur9qcON1QQ false sufficient binding region:1-667 sufficient binding region:232-351 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CW72 uniprotkb:P0CW72 intact:EBI-2620133|uniprotkb:Q777A5 intact:EBI-2620133|uniprotkb:Q777A5 psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620141|imex:IM-20435-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 intact-crc:6389339D7186CAFA|rigid:IJXWRACeU0AGOb92cIKCYy/XDVI false tag:?-?|sufficient binding region:?-? glutathione s tranferase tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P14348 uniprotkb:P0CW72 intact:EBI-2620158|intact:EBI-9645437|uniprotkb:Q777G5 intact:EBI-2620133|uniprotkb:Q777A5 psi-mi:scp_ebvb9(display_long)|uniprotkb:SCP(gene name)|psi-mi:SCP(display_short)|uniprotkb:BFRF3(orf name) psi-mi:barf1_ebvg(display_long)|uniprotkb:BARF1(gene name)|psi-mi:BARF1(display_short)|uniprotkb:33 kDa early protein(gene name synonym)|uniprotkb:p33(gene name synonym) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2620165|imex:IM-20435-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401651.1|interpro:IPR009299(Gammaherpesvirus capsid)|go:"GO:0016032"(viral process)|go:"GO:0019028"(viral capsid)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:7BQX|rcsb pdb:7BR7|rcsb pdb:7BR8|rcsb pdb:7BSI|rcsb pdb:6W19|rcsb pdb:6W2D|rcsb pdb:6W2E refseq:YP_401719.1|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4FA8|dip:DIP-60066N - - - figure legend:Supplementary table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:dBnWcMYacSnhXaIHq5VNw+H4cvg10377 rogid:D3ADKUsYpDVqDM/mOMUXstVGHw410376 intact-crc:F28F2A7930905FA0|rigid:g/0Fut8uY5kWTxV+tw69Vvu5x+Q false tag:?-?|sufficient binding region:1-176 glutathione s tranferase tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0CK47 uniprotkb:P03185 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2620196|uniprotkb:Q777G7 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621663|imex:IM-20435-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 intact-crc:04DA8212736F23DB|rigid:riFMRw8yWUcOAqiOGqFvTM/y25o false sufficient binding region:1-318|glutathione s tranferase tag:?-? sufficient binding region:1-315|tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0CK53 uniprotkb:A0A0C7TRZ7 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 intact:EBI-2621017|uniprotkb:Q1HVH1 psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:a0a0c7trz7_ebvg(display_long)|uniprotkb:BSLF1(gene name)|psi-mi:BSLF1(display_short) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621677|imex:IM-20435-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 interpro:IPR033685|go:"GO:0003896"(DNA primase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2017/03/31 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 rogid:llx/R8yUK2gVl3XbbCH1k6ya6yI10376 intact-crc:EF62ED47812AE4F1|rigid:AboS0HCj37dK8S175klotNQcB9s false sufficient binding region:1-336|glutathione s tranferase tag:?-? sufficient binding region:571-874|tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSQ2 uniprotkb:P0C731 intact:EBI-2621028 intact:EBI-2621032 psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:kr2_ebvg(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621707|imex:IM-20435-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|refseq:YP_401688.1|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10376 intact-crc:2082A37B9D068123|rigid:M088Pmvsev+TxWgpDfjWV7EwsX8 false tag:?-?|sufficient binding region:1-607 glutathione s tranferase tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KST5 uniprotkb:Q66542 intact:EBI-2621066 intact:EBI-2621061 psi-mi:blrf2_ebvg(display_long)|uniprotkb:BLRF2(orf name) psi-mi:q66542_ebvg(display_long)|uniprotkb:BNRF1(gene name)|psi-mi:BNRF1(display_short) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621748|imex:IM-20435-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008642(Herpesvirus BLRF2)|go:"GO:0003677"(DNA binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039503"(suppression by virus of host innate immune response) interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010077(Herpes virus tegument protein/v-FGAM-synthase)|interpro:IPR024346|go:"GO:0019033"(viral tegument)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR029062|interpro:IPR036676|interpro:IPR036921 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:MDNV843jvGJDWdb7mgPXsM/iRAI10376 rogid:Icr9yRMWuFQlx5cIey5tdAhtKvo10376 intact-crc:8C10D30082957154|rigid:LaNoYPn3wjqKvlTZ5kPl4GHSa90 false sufficient binding region:1-162|tag:?-? sufficient binding region:1-1318|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSP5 uniprotkb:Q3KSP5 intact:EBI-2621084 intact:EBI-2621084 psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621763|imex:IM-20435-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 intact-crc:7AA137A9E1E3D0ED|rigid:zTBix1gJNpb3B9hQ2c8tgWbUSos false sufficient binding region:?-?|glutathione s tranferase tag:?-? sufficient binding region:?-?|tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P03209 uniprotkb:Q3KSP5 intact:EBI-2621080|uniprotkb:Q777E4 intact:EBI-2621084 psi-mi:rta_ebvb9(display_long)|uniprotkb:Immediate-early protein Rta(gene name synonym)|uniprotkb:BRLF1(orf name) psi-mi:lf2_ebvg(display_long)|uniprotkb:LF2(gene name)|psi-mi:LF2(display_short) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621777|imex:IM-20435-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401674.1|interpro:IPR004998(Herpesvirus transcription activation factor)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0050434"(positive regulation of viral transcription) interpro:IPR006882(Herpesvirus ORF11 protein)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042802"(identical protein binding) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:9lTewHV10YH3Xy5vErhGn/eyEz010377 rogid:JLHnz9g0kxIzEO2m/N4U9NHqti410376 intact-crc:AF4E89394B1355BC|rigid:aSf/eH0q3We186gRSQ0R1N3QrZs false sufficient binding region:1-605|tag:?-? sufficient binding region:?-?|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSR9 uniprotkb:P0CK49 intact:EBI-2621338 intact:EBI-2621334|uniprotkb:P03194|uniprotkb:Q777F4 psi-mi:portl_ebvg(display_long)|uniprotkb:BBRF1(orf name) psi-mi:teg7_ebvb9(display_long)|uniprotkb:BSRF1(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621792|imex:IM-20435-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002660(Herpesvirus UL6 like)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0006323"(DNA packaging)|rcsb pdb:6RVR|rcsb pdb:6RVS go:"GO:0019033"(viral tegument)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR007619(Herpesvirus U44 protein)|refseq:YP_401663.1 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:bizcWqCEC5rKsvJCV48jHmlbdAg10376 rogid:p/kr3n9JhzCzMyGI4GxbU8uKkz010377 intact-crc:02A2EE0B1A866E50|rigid:mOe/vxzylbufs9qnUt9HAwEFgvg false sufficient binding region:1-613|glutathione s tranferase tag:?-? tag:?-?|sufficient binding region:1-218 - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0CK58 uniprotkb:Q1HVC7 intact:EBI-2621293|uniprotkb:P03229|uniprotkb:Q777A6 intact:EBI-2621352|uniprotkb:Q1HVC6 psi-mi:balf1_ebvb9(display_long)|uniprotkb:BALF1(orf name) psi-mi:scaf_ebva8(display_long)|uniprotkb:Capsid protein P40(gene name synonym)|uniprotkb:Protease precursor(gene name synonym)|uniprotkb:Protein EC-RF3/EC-RF3A(gene name synonym)|uniprotkb:Virion structural protein BVRF2(gene name synonym)|uniprotkb:BVRF2(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621807|imex:IM-20435-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401718.2|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR010677(BALF1) interpro:IPR001847(Peptidase S21, herpesvirus maturational proteinase, assemblin)|refseq:YP_001129501.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039708"(nuclear capsid assembly)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR035443 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2015/12/04 rogid:ZFg3TCa2ZO9XTXB9UJ9DdRJYzhI10377 rogid:Je8NqD4CdcoBK/aR7GXhg4IfYSA82830 intact-crc:734D3C79A245A5E8|rigid:t0HIc2Ka+IugTNyb13O3fgKQgUo false sufficient binding region:1-220|tag:?-? sufficient binding region:261-605|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0C701 uniprotkb:Q66542 intact:EBI-2621366|uniprotkb:Q777G0 intact:EBI-2621061 psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:q66542_ebvg(display_long)|uniprotkb:BNRF1(gene name)|psi-mi:BNRF1(display_short) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621823|imex:IM-20435-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010077(Herpes virus tegument protein/v-FGAM-synthase)|interpro:IPR024346|go:"GO:0019033"(viral tegument)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR029062|interpro:IPR036676|interpro:IPR036921 - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 rogid:Icr9yRMWuFQlx5cIey5tdAhtKvo10376 intact-crc:4680460D2ADB35B1|rigid:i0VaiM3G8CughnfGhH7l0haLhqg false sufficient binding region:171-302|tag:?-? sufficient binding region:1-667|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P0C734 uniprotkb:P0C6Z5 intact:EBI-2621388 intact:EBI-2621381|uniprotkb:Q777E6 psi-mi:btrf1_ebvg(display_long)|uniprotkb:BTRF1(orf name) psi-mi:gp42_ebvg(display_long)|uniprotkb:BZLF2(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621845|imex:IM-20435-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006772(Herpesvirus BTRF1 protein) interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|refseq:YP_401672.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0055036"(virion membrane)|rcsb pdb:5T1D|rcsb pdb:6C5V - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:JMhrq+6M63yNNbXMEasFG2Z0jwg10376 rogid:G0vgvTJ19nuF/gXajIeCo1AoTVw10376 intact-crc:4224B25B8EBC84EF|rigid:lyt0wnxewUJCyR22Rx/RBzRpSnA false sufficient binding region:?-?|tag:?-? sufficient binding region:30-223|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSS3 uniprotkb:A8CSJ8 intact:EBI-2621403 intact:EBI-2621399 psi-mi:gl_ebvg(display_long)|uniprotkb:gL(gene name)|psi-mi:gL(display_short)|uniprotkb:BKRF2(orf name) psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621860|imex:IM-20435-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034708|interpro:IPR020175|go:"GO:0016020"(membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|interpro:IPR038313 interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:7zAlPU2ael0kGkn7vBOoPvR2+n810376 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 intact-crc:9227A186CFBACBBF|rigid:CaU4Vcgxi8QoY0XWfNC2STBQv90 false sufficient binding region:1-137|tag:?-? sufficient binding region:129-386|glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSS4 uniprotkb:Q3KSS4 intact:EBI-2621046 intact:EBI-2621046 psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649508|imex:IM-20435-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:100442373C954A50|rigid:ybhMttsn7uuRkz+kR1VVxFKjEtU false sufficient binding region:379-641|glutathione s tranferase tag:?-? sufficient binding region:379-641|tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q3KSU1 uniprotkb:Q3KSU1 intact:EBI-2621113|uniprotkb:Q3KSU0 intact:EBI-2621113|uniprotkb:Q3KSU0 psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649545|imex:IM-20435-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) - - - figure legend:supplemental table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/03/22 2014/10/16 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 intact-crc:92D0920B0351CBD9|rigid:d7o1I1HwZoA2Wt6her+2jpJhytM false glutathione s tranferase tag:?-?|sufficient binding region:1-479 tag:?-?|sufficient binding region:1-479 - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9UBX5 uniprotkb:Q3KSN9 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 intact:EBI-2621948 psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:dnbi_ebvg(display_long)|uniprotkb:DBP(gene name)|psi-mi:DBP(display_short)|uniprotkb:BALF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621961|imex:IM-20435-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 interpro:IPR000635(Viral ssDNA-binding protein)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019033"(viral tegument)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR043031|interpro:IPR035989 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 rogid:m6+V7+fYp9W0Hbb8rhPMuGVmknQ10376 intact-crc:D8E35D5BFE49D77E|rigid:4IzUHBG6+JV4l6XHAVT5OsWcnqg false - sufficient binding region:566-1128 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15723 uniprotkb:Q3KSN9 intact:EBI-956941|uniprotkb:E9PCX3|uniprotkb:Q15724|uniprotkb:Q15725|uniprotkb:Q6P1K5|ensembl:ENSP00000368868 intact:EBI-2621948 psi-mi:elf2_human(display_long)|uniprotkb:ELF2(gene name)|psi-mi:ELF2(display_short)|uniprotkb:NERF(gene name synonym)|uniprotkb:E74-like factor 2(gene name synonym)|uniprotkb:New ETS-related factor(gene name synonym) psi-mi:dnbi_ebvg(display_long)|uniprotkb:DBP(gene name)|psi-mi:DBP(display_short)|uniprotkb:BALF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621952|imex:IM-20435-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263387.1|refseq:NP_006865.1|refseq:NP_973728.1|refseq:NP_001263386.1|refseq:NP_001263388.1|refseq:XP_005262861.1|refseq:NP_001317965.1|ensembl:ENSG00000109381(gene)|ensembl:ENST00000379550(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8939245 interpro:IPR000635(Viral ssDNA-binding protein)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019033"(viral tegument)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR043031|interpro:IPR035989 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:I+5r30P0sfIJfJSYkJwjpbWxUnE9606 rogid:m6+V7+fYp9W0Hbb8rhPMuGVmknQ10376 intact-crc:329781A93617A71B|rigid:GryasA4FTB5jP0qgfmAlZtqkLNA false - sufficient binding region:1-565 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:P0C762 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621988|imex:IM-20435-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:339C8595DF5E07AB|rigid:WXvkrOyrwh7jLppmhWdFbF9pFkg false - sufficient binding region:753-857 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:Q8N2S1 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621979|imex:IM-20435-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606 intact-crc:1AD9DA5F780CC4EB|rigid:+UKkGbB3MADvIFFcGnyFeIcLp7M false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28799 uniprotkb:P0C762 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621970|imex:IM-20435-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:DD60B6E9C2AFBD9B|rigid:TtR5X62Ih8RD5QqxnNx6AbWC0o4 false - sufficient binding region:753-857 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:Q8TAS6 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-2622017 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:q8tas6_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622015|imex:IM-20435-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 interpro:IPR002049(EGF-like, laminin)|interpro:IPR013015(Laminin IV)|refseq:NP_002282.2|interpro:IPR000742(EGF-like, type 3) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:HCEb+we2ZRZClQiN5+RQx/CcT7g9606 intact-crc:F64ECAF54E487720|rigid:g/vtruDUMrBrZy6qw5c5eVLIyCk false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:P02751 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622006|imex:IM-20435-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2019/10/18 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 intact-crc:C2D9B559132F461A|rigid:Ivmb6OcQhVAGxf/+WpmWbLds1s0 false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:P63010 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-432924|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-28970775|ensembl:ENSP00000482315|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2621997|imex:IM-20435-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_001025177.1|refseq:NP_001273.1|ensembl:ENST00000610402|ensembl:ENSP00000483185|ensembl:ENST00000618940|ensembl:ENSP00000482835|ensembl:ENSP00000482315|go:"GO:0005048"(signal sequence binding)|go:"GO:0005829"(cytosol)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000621914(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|refseq:XP_011522757.1|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035904"(aorta development)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0005886"(plasma membrane)|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_016879773.1|refseq:XP_016879775.1|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV8|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|dip:DIP-33098N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606 intact-crc:B0FCEBE6A65FDE48|rigid:70emD2zYOQ7cCMy9v7hLEXU/TdA false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:P08670 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622052|imex:IM-20435-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 intact-crc:AC2B8401F0A17E9B|rigid:NPdWWluJv5kfAwcmWVr8HXPngfk false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:Q12933 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622043|imex:IM-20435-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:8CFB923B6DFAD8C4|rigid:+bYlth/wGo9Zrn+heouKBPp+hb0 false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:P18545 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-2622029|uniprotkb:Q3KP63|uniprotkb:Q7Z3U8|ensembl:ENSP00000328412|ensembl:ENSP00000458167|ensembl:ENSP00000461464 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:cnrg_human(display_long)|uniprotkb:PDEG(gene name synonym)|uniprotkb:PDE6G(gene name)|psi-mi:PDE6G(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622034|imex:IM-20435-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:XP_006722005.1|refseq:NP_002593.1|refseq:XP_016880224.1|refseq:XP_016880225.1|ensembl:ENSG00000185527(gene)|ensembl:ENST00000331056(transcript)|ensembl:ENST00000571004(transcript)|ensembl:ENST00000571224(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007601"(visual perception)|go:"GO:0030507"(spectrin binding)|go:"GO:0030553"(cGMP binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0047555"(3',5'-cyclic-GMP phosphodiesterase activity)|go:"GO:0050896"(response to stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR006952(Retinal cGMP phosphodiesterase, gamma subunit)|interpro:IPR037030|mint:P18545|rcsb pdb:3JWR|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-4086398 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:gsjKwWpx+sGGCwYus6BYMNKbnv89606 intact-crc:435DF2EF1EFD8F4D|rigid:UuRZQtwGW0INx8zRGsQ3EMtZWtc false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:Q5T124 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-746004|uniprotkb:Q5T117|uniprotkb:Q5T120|uniprotkb:Q5T125|uniprotkb:Q5T126|uniprotkb:Q5T129|uniprotkb:Q5T131|uniprotkb:Q5T133|uniprotkb:Q63HM6|uniprotkb:Q71RB3|uniprotkb:Q8IY27|uniprotkb:Q8N1L6|uniprotkb:Q8N9M4|uniprotkb:Q8NA18|uniprotkb:Q8NFE3|uniprotkb:Q8NFE4|uniprotkb:Q8NFE6|uniprotkb:D3DPK6|ensembl:ENSP00000363338|ensembl:ENSP00000363339 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:ubx11_human(display_long)|uniprotkb:Socius(gene name synonym)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:SOC(gene name synonym)|uniprotkb:PP2243(orf name)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622088|imex:IM-20435-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_001070730.1|refseq:NP_663320.2|refseq:NP_892120.2|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9696264|ensembl:ENSG00000158062(gene)|ensembl:ENST00000374221(transcript)|ensembl:ENST00000374222(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:sTWknIh+W0jcWm0/2rZ0ZIG4zUs9606 intact-crc:D100BF0DE9D3E048|rigid:M2LIGvxD8siLlvVbOXItbbcJYaY false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C762 uniprotkb:Q9UBX5 intact:EBI-2621559|uniprotkb:Q3KSP0 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622079|imex:IM-20435-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 intact-crc:072DC85ACF7C8486|rigid:h1uGE0X2IqFaF2FHaFPg3rXaynE false sufficient binding region:753-857 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JY77 uniprotkb:P0C762 intact:EBI-2514717|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934|uniprotkb:Q96LA1|uniprotkb:O43168 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:gasp1_human(display_long)|uniprotkb:GPRASP1(gene name)|psi-mi:GPRASP1(display_short)|uniprotkb:GASP(gene name synonym)|uniprotkb:KIAA0443(gene name synonym) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622070|imex:IM-20435-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198932(gene)|ensembl:ENST00000361600(transcript)|ensembl:ENST00000415986(transcript)|ensembl:ENST00000444152(transcript)|ensembl:ENST00000537097(transcript)|ensembl:ENST00000652542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:1990172"(G protein-coupled receptor catabolic process)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:XP_016885470.1|refseq:XP_016885471.1|refseq:NP_001092880.1|refseq:NP_001092881.1|refseq:NP_001171656.1|refseq:NP_055525.3|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934 interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:hV+EvmQTl209eBHMYEB0Pq21jYo9606 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:CD880B64594E91A6|rigid:q8HYxCbE0ycW2rnGz5bq/zEUcxc false - sufficient binding region:753-857 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04275 uniprotkb:P0C762 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622061|imex:IM-20435-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:40FB4079132F4792|rigid:bU48kJ6bxUh84pqS7SeN9D0HIAI false - sufficient binding region:753-857 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12814 uniprotkb:P0C701 intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403 intact:EBI-2621366|uniprotkb:Q777G0 psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622121|imex:IM-20435-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034 interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:guTURyt26f1ort4NAlYyabNc+WE9606 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 intact-crc:51B946F0D9D23BE5|rigid:lDwVnHCgUJ7sygpbX6slDaic+3s false - sufficient binding region:171-302 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHV2 uniprotkb:P0C701 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 intact:EBI-2621366|uniprotkb:Q777G0 psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622112|imex:IM-20435-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2 interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 intact-crc:DF44B0BE43CD7432|rigid:1kfTt3C7vhJfRRZssFzWwTY/+kE false - sufficient binding region:171-302 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1KXE4 uniprotkb:P0C762 intact:EBI-2622099|uniprotkb:Q6NZ40|uniprotkb:Q2TAZ6|ensembl:ENSP00000374565|ensembl:ENSP00000387051 intact:EBI-2621559|uniprotkb:Q3KSP0 psi-mi:f168b_human(display_long)|uniprotkb:KIAA0280L(gene name synonym)|uniprotkb:p20(gene name synonym)|uniprotkb:FAM168B(gene name)|psi-mi:FAM168B(display_short)|uniprotkb:MANI(gene name synonym) psi-mi:gb_ebvg(display_long)|uniprotkb:BALF4(orf name)|uniprotkb:gB(gene name)|psi-mi:gB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622097|imex:IM-20435-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308672.1|refseq:NP_001009993.2|refseq:XP_016858816.1|ensembl:ENSG00000152102(gene)|ensembl:ENST00000389915(transcript)|ensembl:ENST00000409185(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR029247|refseq:NP_001308673.1|refseq:NP_001308674.1|refseq:NP_001308675.1|refseq:NP_001308676.1|refseq:NP_001308677.1 interpro:IPR000234(Herpesvirus Glycoprotein B)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR038631|interpro:IPR035377|interpro:IPR035381 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:b76fBaarMDthz23BFzK99JbKrWU9606 rogid:52vwUHqZi0HsEBvBpLaE3N/huvU10376 intact-crc:97BB26A0E5A0B811|rigid:J2dfjMD3v0Gn76cIcXXzLxirtUA false - sufficient binding region:753-857 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HCE6 uniprotkb:Q3KSR8 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-2622148 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:cep1_ebvg(display_long)|uniprotkb:BBRF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622164|imex:IM-20435-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 interpro:IPR002600(Herpesvirus UL7-like protein)|go:"GO:0019033"(viral tegument)|go:"GO:0044177"(host cell Golgi apparatus)|rcsb pdb:6LQN|rcsb pdb:6LQO - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2018/09/18 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:WJF//Qy/RKco2mW2HEHxfU0lEvU10376 intact-crc:8AC26AF28C4EFC8F|rigid:3PHVROmszpK+GE8Oqdg5hoRa6Ng false - sufficient binding region:1-278 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRD5 uniprotkb:Q3KSR8 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-2622148 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:cep1_ebvg(display_long)|uniprotkb:BBRF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622155|imex:IM-20435-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 interpro:IPR002600(Herpesvirus UL7-like protein)|go:"GO:0019033"(viral tegument)|go:"GO:0044177"(host cell Golgi apparatus)|rcsb pdb:6LQN|rcsb pdb:6LQO - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:WJF//Qy/RKco2mW2HEHxfU0lEvU10376 intact-crc:C3249A8F42AD3F83|rigid:/Fjh+543wVoAhPTfHb82mvh7u+A false - sufficient binding region:1-278 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96BY9 uniprotkb:P0C701 intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255 intact:EBI-2621366|uniprotkb:Q777G0 psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name) psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622139|imex:IM-20435-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 intact-crc:2CCDA643B95CBAE7|rigid:rsyc0LHSFygduXQuUwa/nJOvh88 false - sufficient binding region:1-147 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C701 uniprotkb:P14618 intact:EBI-2621366|uniprotkb:Q777G0 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:rir2_ebvg(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:BaRF1(orf name) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622130|imex:IM-20435-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034715|refseq:YP_401656.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|interpro:IPR033909|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR012348(Ribonucleotide reductase-related) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5Y+pks+zCR8RmDOEhLWksjzYeuU10376 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 intact-crc:309F07B4794AD686|rigid:bKkcFT9MZFNpFwW12Awuaz07GXw false sufficient binding region:171-302 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1HVD6 uniprotkb:Q49A88 intact:EBI-2621542 intact:EBI-751035|intact:EBI-2622203|intact:EBI-2858142|uniprotkb:B7Z2T2|uniprotkb:B8ZZ58|intact:EBI-946963|intact:EBI-1104778|uniprotkb:Q7Z3N3|uniprotkb:Q86T30|uniprotkb:Q8WUJ8|uniprotkb:Q96K47|uniprotkb:Q9H9A3|uniprotkb:Q9UFH0|uniprotkb:Q8IWF8|uniprotkb:B8ZZ41|uniprotkb:D3DN98|uniprotkb:B7Z2Q3 psi-mi:q1hvd6_ebva8(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short) psi-mi:ccd14_human(display_long)|uniprotkb:CCDC14(gene name)|psi-mi:CCDC14(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622207|imex:IM-20435-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129492.1|interpro:IPR002690(Herpesvirus VP23-like capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus) refseq:NP_073594.4|refseq:NP_001295246.1|refseq:XP_005247767.1|refseq:XP_005247768.1|refseq:XP_005247770.1|refseq:XP_005247771.1|refseq:XP_016862545.1|refseq:XP_016862547.1|refseq:XP_016862548.1|mint:Q49A88|dip:DIP-47727N|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0021762"(substantia nigra development)|go:"GO:0034451"(centriolar satellite)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR029343 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:hMQYfBwXv5pPVOHgG+RuR0qrSLs82830 rogid:y1bU4io/NA6LIX+pwRkB8gstVuY9606 intact-crc:9A2C57B70F9ED7E7|rigid:Q4o7NQyii/6r3cyD5Eh1nJ3iJZk false sufficient binding region:1-301 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:Q3KSR7 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-2622173 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:gm_ebvg(display_long)|uniprotkb:BBRF3(orf name)|uniprotkb:gM(gene name)|psi-mi:gM(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622194|imex:IM-20435-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 interpro:IPR000785(Herpsevirus integral membrane protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:WX7bNxVuFNQmws5147TH7qgXc4c10376 intact-crc:E2626C3E3D92100C|rigid:ED+2cy5XSlHa0UcpeTtw4rkU/pY false - sufficient binding region:43-75 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02818 uniprotkb:Q3KSR7 intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923 intact:EBI-2622173 psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short) psi-mi:gm_ebvg(display_long)|uniprotkb:BBRF3(orf name)|uniprotkb:gM(gene name)|psi-mi:gM(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622177|imex:IM-20435-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome) interpro:IPR000785(Herpsevirus integral membrane protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606 rogid:WX7bNxVuFNQmws5147TH7qgXc4c10376 intact-crc:BC3DBCA8B2B3331B|rigid:l4hpW4lxSJvghvh9NnLPMHMmtKA false - sufficient binding region:43-75 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03225 uniprotkb:A4D0U5 intact:EBI-2621153|uniprotkb:Q777C4 intact:EBI-2622243 psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:a4d0u5_human(display_long)|uniprotkb:hCG_39086(orf name)|uniprotkb:tcag7.1(orf name)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622247|imex:IM-20435-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) mint:A4D0U5|interpro:IPR033724|refseq:NP_056456.1|interpro:IPR010442(PET)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030054"(cell junction)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR027683|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 rogid:19bO7/55OMgcMT5lx1404AluskE9606 intact-crc:79B5AF8B7032429D|rigid:ic31sigNJLK/HL8k1PzoLLGYIbw false sufficient binding region:1-420 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N2S1 uniprotkb:P03225 intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905 intact:EBI-2621153|uniprotkb:Q777C4 psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short) psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622234|imex:IM-20435-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379 refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 intact-crc:FE27445C8792ACBE|rigid:vHU+8GCsOn3MhME6QI6nbheDfn4 false - sufficient binding region:1-420 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13164 uniprotkb:Q1HVD6 intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968 intact:EBI-2621542 psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym) psi-mi:q1hvd6_ebva8(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622225|imex:IM-20435-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion) refseq:YP_001129492.1|interpro:IPR002690(Herpesvirus VP23-like capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606 rogid:hMQYfBwXv5pPVOHgG+RuR0qrSLs82830 intact-crc:7DF571BD95C8CF23|rigid:RqDOQ0B8S9tR+8h+zSawshQi42o false - sufficient binding region:1-301 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53634 uniprotkb:Q1HVD6 intact:EBI-1047323|uniprotkb:A8K7V2|uniprotkb:Q53G93|uniprotkb:Q71E75|uniprotkb:Q71E76|uniprotkb:Q7M4N9|uniprotkb:Q8WY99|ensembl:ENSP00000227266|uniprotkb:Q8WYA7|uniprotkb:Q8WYA8|uniprotkb:Q7Z3G7|uniprotkb:Q7Z5U7|uniprotkb:B5MDD5|uniprotkb:Q2HIY8 intact:EBI-2621542 psi-mi:catc_human(display_long)|uniprotkb:Dipeptidyl peptidase I(gene name synonym)|uniprotkb:Cathepsin C(gene name synonym)|uniprotkb:Cathepsin J(gene name synonym)|uniprotkb:Dipeptidyl transferase(gene name synonym)|uniprotkb:CTSC(gene name)|psi-mi:CTSC(display_short)|uniprotkb:CPPI(gene name synonym) psi-mi:q1hvd6_ebva8(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622216|imex:IM-20435-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0031642"(negative regulation of myelination)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR014882(Cathepsin C exclusion)|interpro:IPR025660|interpro:IPR025661|interpro:IPR036496|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR038765|interpro:IPR039412|mint:P53634|rcsb pdb:1K3B|go:"GO:0042802"(identical protein binding)|rcsb pdb:2DJF|rcsb pdb:2DJG|rcsb pdb:3PDF|rcsb pdb:4CDC|rcsb pdb:4CDD|rcsb pdb:4CDE|rcsb pdb:4CDF|rcsb pdb:4OEL|rcsb pdb:4OEM|reactome:R-HSA-204005|reactome:R-HSA-2132295|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0051087"(chaperone binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-5694530|reactome:R-HSA-6798695|ensembl:ENSG00000109861(gene)|ensembl:ENST00000227266(transcript)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006955"(immune response)|go:"GO:0007568"(aging)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016020"(membrane)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031404"(chloride ion binding)|refseq:NP_001805.3|refseq:NP_680475.1|refseq:NP_001107645.1 refseq:YP_001129492.1|interpro:IPR002690(Herpesvirus VP23-like capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:vA2MxBAxHODNS4fo9Nvm6UJGW149606 rogid:hMQYfBwXv5pPVOHgG+RuR0qrSLs82830 intact-crc:2DBD92324629CC0B|rigid:V8zopg3QgTpzBpgoyJm0QHJkE9Y false - sufficient binding region:1-301 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:P03225 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-2621153|uniprotkb:Q777C4 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622283|imex:IM-20435-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 intact-crc:8A581E6E1368506B|rigid:aMr2ywDzP4RBW1dr4kXCaYURbfU false - sufficient binding region:208-420 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61289 uniprotkb:P03225 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 intact:EBI-2621153|uniprotkb:Q777C4 psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622274|imex:IM-20435-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 intact-crc:C7146010CF199715|rigid:IgjPmWURE4zd3fRi/1H1xt87Obk false - sufficient binding region:208-420 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95236 uniprotkb:P03225 intact:EBI-2622258|uniprotkb:Q9BQA3|uniprotkb:B1AHI5|uniprotkb:B1AHI4|uniprotkb:Q9BQ82|uniprotkb:Q5U5N4|ensembl:ENSP00000344577 intact:EBI-2621153|uniprotkb:Q777C4 psi-mi:apol3_human(display_long)|uniprotkb:Apolipoprotein L-III(gene name synonym)|uniprotkb:TNF-inducible protein CG12-1(gene name synonym)|uniprotkb:APOL3(gene name)|psi-mi:APOL3(display_short) psi-mi:bdlf2_ebvb9(display_long)|uniprotkb:BDLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622256|imex:IM-20435-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055164.1|refseq:NP_085147.1|refseq:NP_663614.1|refseq:XP_006724387.1|refseq:NP_663615.1|refseq:NP_663616.1|refseq:NP_663617.1|refseq:XP_016884441.1|ensembl:ENSG00000128284(gene)|ensembl:ENST00000349314(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR008405(Apolipoprotein L)|refseq:XP_006724388.1 refseq:YP_401695.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Iqurc66QUo7OVUtTMnjwn3pdr9w9606 rogid:c2j3BYWgBb4ev9ypl9RlHNkRJ2g10377 intact-crc:7A08DCC404539743|rigid:WV5GiCLb6p44H1pVxlBuWu+SYgg false - sufficient binding region:1-184 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2622317 uniprotkb:P0CK56 - intact:EBI-2622323|uniprotkb:P03223|uniprotkb:Q777C6 psi-mi:a6nid9_human(display_short)|psi-mi:EBI-2622317(display_long)|uniprotkb:MFSD1(gene name)|psi-mi:MFSD1(display_short) psi-mi:ul92_ebvb9(display_long)|uniprotkb:BDLF4(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622321|imex:IM-20435-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A6NID9(uniprot-removed-ac) interpro:IPR004289(UL92)|refseq:YP_401693.1 - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:ioL8jtAWsmA6rFDDlW3PSqej5Og9606 rogid:QxORu+WaY0AUY1Irz0J6gQi+lCE10377 intact-crc:CD2A906D61B73BBF|rigid:sU+QVgMepByVTkRsz2P+2FEo4A0 false - sufficient binding region:1-225 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A0C7TUY8 uniprotkb:Q9UHV2 intact:EBI-2622305|uniprotkb:Q1HVD9 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 psi-mi:a0a0c7tuy8_ebvg(display_long)|uniprotkb:BDLF3.5(gene name)|psi-mi:BDLF3.5(display_short) psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622308|imex:IM-20435-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2017/03/31 rogid:P265H8Ma6VIqfwJENGem82zGefc10376 rogid:40dvjniwxY/UQiyoVREicctpWe09606 intact-crc:F416A368D73F113F|rigid:uQbLuzfTwd4fcHysOSbS7ht0zBE false sufficient binding region:1-77 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03224 uniprotkb:Q9NSC5 intact:EBI-2622292|intact:EBI-9645225|uniprotkb:Q777C5 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:bdlf3_ebvb9(display_long)|uniprotkb:BDLF3(orf name) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622296|imex:IM-20435-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401694.1|go:"GO:0016021"(integral component of membrane) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:TyAQL55kgXceWNDb8lGLp4KrgEI10377 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:1E3210ABD6B05B2B|rigid:FEGsstE+tWUuFYgwkTjWHLm5H7s false sufficient binding region:35-183 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBX5 uniprotkb:P0CK47 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622365|imex:IM-20435-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:CCAE592F6BBC2405|rigid:CKhrKQ9KemE/w6Cl2A1xR5tx+ec false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q8N2S1 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622356|imex:IM-20435-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606 intact-crc:D15A4B2ADCCC6468|rigid:Xgo+9IYZz6hjauUVbhBdx39o4Rg false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:P28799 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622347|imex:IM-20435-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:5BAD9BA72263634B|rigid:s01OVk6BinifqEEKy643HhroRvg false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK56 uniprotkb:Q96IR5 intact:EBI-2622323|uniprotkb:P03223|uniprotkb:Q777C6 intact:EBI-2622334 psi-mi:ul92_ebvb9(display_long)|uniprotkb:BDLF4(orf name) psi-mi:q96ir5_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622338|imex:IM-20435-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004289(UL92)|refseq:YP_401693.1 interpro:IPR019540|refseq:NP_149975.1|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:QxORu+WaY0AUY1Irz0J6gQi+lCE10377 rogid:3NI55uOP96naffYtiL9viplrKF89606 intact-crc:C427E35755A38FE7|rigid:h1HD03cC19fc3vMeOWIJp0D1gew false sufficient binding region:1-225 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q02818 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622405|imex:IM-20435-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606 intact-crc:B86B40AB8FBEBC06|rigid:Mj5AT9iHoZUiTg/ciqkwQcwffHI false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q12805 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622396|imex:IM-20435-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606 intact-crc:4088CC69690F8777|rigid:zSp+zxGbObh7K6q12IbKDXTu/Wc false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:P46379 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622387|imex:IM-20435-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 intact-crc:DEF8CEF02AC0E926|rigid:131+h66X5p83JTLI0HlnSpeFC3I false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WXE0 uniprotkb:P0CK47 intact:EBI-2622376|uniprotkb:B4DTT3|uniprotkb:Q9ULT1|intact:EBI-3446386|uniprotkb:B7Z9H1|uniprotkb:Q7LG69|ensembl:ENSP00000325355 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:cski2_human(display_long)|uniprotkb:CASK-interacting protein 2(gene name synonym)|uniprotkb:CASKIN2(gene name)|psi-mi:CASKIN2(display_short)|uniprotkb:KIAA1139(gene name synonym) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622374|imex:IM-20435-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001136115.1|refseq:NP_065804.2|ensembl:ENSP00000325355|ensembl:ENST00000433559|ensembl:ENSP00000406963|ensembl:ENSG00000177303(gene)|ensembl:ENST00000321617(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR027013|interpro:IPR032117|interpro:IPR032232|interpro:IPR035497|interpro:IPR035498|interpro:IPR035499|interpro:IPR036028|interpro:IPR036770|rcsb pdb:2KE9|rcsb pdb:4IS7|rcsb pdb:5L1M go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:XLOkvhXMcYWuzRMNrR3q+K4PoCg9606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:B3C3A08A953D7976|rigid:5yFAGH8/9kSkBIFGTZGhf7p3rnI false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q9Y228 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622440|imex:IM-20435-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 intact-crc:03AB1C8F83F5A75D|rigid:p+xgNPgCcCtZ9Emj6vF0XCSiCS0 false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:B2RCM5 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622428 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:b2rcm5_human(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622431|imex:IM-20435-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0048251"(elastic fiber assembly)|interpro:IPR026824|interpro:IPR026823|interpro:IPR009030(Growth factor, receptor) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:mj5DFcHcE4+eN3yYXtf2RgduIeM9606 intact-crc:3AE7338AD3507B8C|rigid:FBqRj+s/BVJdR962/hbsBIHyTZQ false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q9UEW3 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622414|uniprotkb:B4DW79|uniprotkb:Q9Y5S3|ensembl:ENSP00000318916 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:marco_human(display_long)|uniprotkb:SCARA2(gene name synonym)|uniprotkb:Macrophage receptor with collagenous structure(gene name synonym)|uniprotkb:Scavenger receptor class A member 2(gene name synonym)|uniprotkb:MARCO(gene name)|psi-mi:MARCO(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622419|imex:IM-20435-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:XP_011510384.1|refseq:NP_006761.1|ensembl:ENSG00000019169(gene)|ensembl:ENST00000327097(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005581"(collagen trimer)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045087"(innate immune response)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|interpro:IPR001190(Speract/scavenger receptor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036772|reactome:R-HSA-3000480 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:iGEW9ztEEgd6+cFFGZsHAsyBo0E9606 intact-crc:8A306DFFF3076F0F|rigid:noYt5bJZH6riaSLujTmv1BKe8fc false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:A1L0V1 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622451 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:a1l0v1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622449|imex:IM-20435-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:lu+3IeoAzwMY/KSxeuhvyWicesw9606 intact-crc:0BF90AE4F06D74A6|rigid:qANUi/X1+Xa1S3rlO+m0N3mtGws false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q86V58 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622462 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:q86v58_human(display_long)|uniprotkb:FBLN2(gene name)|psi-mi:FBLN2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622467|imex:IM-20435-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_001004019.1|refseq:NP_001158507.1|refseq:NP_001989.2|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR037286|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR026823|interpro:IPR009030(Growth factor, receptor) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:/D8ClwFnIPMMKbssi9T5fbfbV5g9606 intact-crc:FAE47F7521425D5F|rigid:jwy/M4DJpIxdU57rAjx/qhIm2yk false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q9NSC5 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622503|imex:IM-20435-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:57E7AE843FE56A59|rigid:SaxdSQa3Zez1w3MtKZv7+AIrcvI false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63279 uniprotkb:P0CK47 intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622494|imex:IM-20435-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:37DC5CB90E31439A|rigid:cL3Iv6/hZXKxNWZVpLxVvK5ujj0 false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:P0CK47 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622485|imex:IM-20435-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:BC9E162BAEC34043|rigid:VHkDJVf7BUmbFUqBpiK5tJVBnoI false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55268 uniprotkb:P0CK47 intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622476|imex:IM-20435-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:FA6A87B6D3928523|rigid:5SpsngXn6QFb+3nMDXMClePBDB8 false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHF1 uniprotkb:P0CK47 intact:EBI-949532|ensembl:ENSP00000307843|ensembl:ENSP00000360763|ensembl:ENSP00000360764|ensembl:ENSP00000385639|uniprotkb:Q5M7Y5|uniprotkb:Q5VUD5|uniprotkb:Q96EG0|uniprotkb:B3KRP0|uniprotkb:M9VTX9 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 psi-mi:egfl7_human(display_long)|uniprotkb:Multiple epidermal growth factor-like domains protein 7(gene name synonym)|uniprotkb:Zneu1(gene name synonym)|uniprotkb:Vascular endothelial statin(gene name synonym)|uniprotkb:NOTCH4-like protein(gene name synonym)|uniprotkb:EGFL7(gene name)|psi-mi:EGFL7(display_short)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:UNQ187/PRO1449(orf name) psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622539|imex:IM-20435-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172889(gene)|ensembl:ENST00000308874(transcript)|ensembl:ENST00000371698(transcript)|ensembl:ENST00000371699(transcript)|ensembl:ENST00000406555(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018097|mint:Q9UHF1|go:"GO:0005576"(extracellular region)|refseq:NP_057299.1|refseq:NP_958854.1|refseq:XP_011517066.1|refseq:XP_011517067.1|refseq:XP_011517068.1 go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:HzaJXQm4JE8bXXE+/ugmqGjpjZA9606 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 intact-crc:939799D9BD0386BD|rigid:83Z0Na5aTppRLu5uiiNRq2YsBL4 false - sufficient binding region:1-318 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q6PKC3 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622530|imex:IM-20435-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_056998.4|refseq:NP_001290376.1|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066(gene)|ensembl:ENST00000356957(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606 intact-crc:6306F5D8CAD83C18|rigid:7KpvEdvicRofr1WCfr7sMd3wTtg false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q9UBP4 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-954409|ensembl:ENSP00000314910|ensembl:ENSP00000379762|ensembl:ENSP00000506835|uniprotkb:Q9ULB7|uniprotkb:A8K1I2|uniprotkb:D3DQW1 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:dkk3_human(display_long)|uniprotkb:REIC(gene name synonym)|uniprotkb:UNQ258/PRO295(orf name)|uniprotkb:DKK3(gene name)|psi-mi:DKK3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622521|imex:IM-20435-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 ensembl:ENSG00000050165(gene)|ensembl:ENST00000326932(transcript)|ensembl:ENST00000396505(transcript)|ensembl:ENST00000683431(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030325"(adrenal gland development)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0039706"(co-receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1902613"(negative regulation of anti-Mullerian hormone signaling pathway)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|interpro:IPR039863|mint:Q9UBP4|refseq:NP_001018067.1|refseq:NP_037385.2|refseq:NP_056965.3|refseq:XP_006718241.1|refseq:NP_001317149.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:pnbEZP5fAWw3Qxg1gB1sjP0Oyeo9606 intact-crc:29BE3B24F1A706A9|rigid:m4PzC+6x7tbyxNm0gkuQ8VHP888 false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q93062 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622512|imex:IM-20435-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 intact-crc:4F776FD0CC4ED94F|rigid:fRsAQkN0wul2ZuIH47ayBiMFuJk false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04275 uniprotkb:P03185 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 intact:EBI-2620196|uniprotkb:Q777G7 psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622571|imex:IM-20435-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 intact-crc:FC5BE0A5980C203C|rigid:yqn5OI0OK6Rg0xr+TXKkDJyHQPk false - sufficient binding region:1-315 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03185 uniprotkb:P28799 intact:EBI-2620196|uniprotkb:Q777G7 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622562|imex:IM-20435-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:D57F70768F4C9EA4|rigid:MUcYZqIO6gazefy7ChyGBNnqo6A false sufficient binding region:1-315 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK47 uniprotkb:Q96NA8 intact:EBI-2620189|uniprotkb:P03183|uniprotkb:Q777G9 intact:EBI-2622548|uniprotkb:B7ZLB0|uniprotkb:Q14D03|ensembl:ENSP00000428763 psi-mi:nec1_ebvb9(display_long)|uniprotkb:NEC1(gene name)|psi-mi:NEC1(display_short)|uniprotkb:BFLF2(orf name) psi-mi:tsna1_human(display_long)|uniprotkb:TSNARE1(gene name)|psi-mi:TSNARE1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622553|imex:IM-20435-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR021152|refseq:YP_401647.1 refseq:NP_659440.2|refseq:XP_016868667.1|ensembl:ENSG00000171045(gene)|ensembl:ENST00000524325(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)|interpro:IPR028002 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eVMtUKb/8El/P00DFbDWKLie1tQ10377 rogid:JqVE8TDTpJQYNgfvv3CRzdoyLbE9606 intact-crc:AAE62ED2FB2B124C|rigid:aobHUXZbkgNvltjDoSkmZiHsBT0 false sufficient binding region:1-318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYM8 uniprotkb:P0CK53 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622619|imex:IM-20435-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 intact-crc:FFA89FEA316C239F|rigid:DDBz7q5bqJDxK/KzgtX6xgRp+Po false - sufficient binding region:1-336 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03185 uniprotkb:Q9NSC5 intact:EBI-2620196|uniprotkb:Q777G7 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622610|imex:IM-20435-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:7A069AA6563EACA2|rigid:Et1aCyXPNBXa1Hi5+XD0JIYkcWw false sufficient binding region:1-315 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03185 uniprotkb:O75094 intact:EBI-2620196|uniprotkb:Q777G7 intact:EBI-2622593|uniprotkb:O95804|uniprotkb:Q9UFH5|uniprotkb:A6H8U9|ensembl:ENSP00000430333|uniprotkb:J3KNP3 psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:slit3_human(display_long)|uniprotkb:KIAA0814(gene name synonym)|uniprotkb:MEGF5(gene name synonym)|uniprotkb:SLIL2(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains protein 5(gene name synonym)|uniprotkb:UNQ691/PRO1336(orf name)|uniprotkb:SLIT3(gene name)|psi-mi:SLIT3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622601|imex:IM-20435-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) refseq:NP_003053.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428542|ensembl:ENSG00000184347(gene)|ensembl:ENST00000519560(transcript)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|refseq:NP_001258875.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 rogid:Qazwnc23w/tZ8NsF8G3ZLSEF1SE9606 intact-crc:1E3D3BA87B1F0C8B|rigid:XrAjLTxMKKkpXNWNQftxXfMbrYU false sufficient binding region:1-315 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03185 uniprotkb:Q99873 intact:EBI-2620196|uniprotkb:Q777G7 intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914 psi-mi:nec2_ebvb9(display_long)|uniprotkb:NEC2(gene name)|psi-mi:NEC2(display_short)|uniprotkb:BFRF1(orf name) psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622580|imex:IM-20435-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401649.1|interpro:IPR007626(Herpesvirus virion protein UL34)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044201"(host cell nuclear inner membrane)|go:"GO:0046765"(viral budding from nuclear membrane) ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2018/04/06 rogid:8LYYAwlAFTFmTh2HUQJuTAHH0E410377 rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606 intact-crc:ED879C0393A05576|rigid:/YYGWtpftp2wjHkX7S6k94SpDnc false sufficient binding region:1-315 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK53 uniprotkb:Q96CV9 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032 psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622646|imex:IM-20435-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2018/04/06 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606 intact-crc:9318DC4EDE0B4824|rigid:xydyzlt1jQWC8t94zmR//2o9I0A false sufficient binding region:1-336 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:P0CK53 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622637|imex:IM-20435-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 intact-crc:444FE507095C0A24|rigid:hW+9h631/5c86AyQMwGrrAhdb3Q false - sufficient binding region:1-336 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q71U36 uniprotkb:P0CK53 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622628|imex:IM-20435-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 intact-crc:195FD1E2BC650892|rigid:88GVHYjGX+ukm1qobdOe1tNvMtA false - sufficient binding region:1-336 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C736 uniprotkb:P28799 intact:EBI-2622693 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622691|imex:IM-20435-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:1E0E916936AB299F|rigid:ybIM2gEVQD7uvSmPY77SzQqOLHU false sufficient binding region:1-191 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C731 uniprotkb:Q13576 intact:EBI-2621032 intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364 psi-mi:kr2_ebvg(display_long)|uniprotkb:BGLF4(orf name) psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622682|imex:IM-20435-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|refseq:YP_401688.1|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10376 rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606 intact-crc:B1CE7B6CD772CAC4|rigid:RqaeSrNOqfJ0QiLR1xq9aaMxh/M false sufficient binding region:1-429 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01857 uniprotkb:P0C731 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 intact:EBI-2621032 psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:kr2_ebvg(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622673|imex:IM-20435-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|refseq:YP_401688.1|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10376 intact-crc:59DE9C74582CB1DF|rigid:xXj1bgkTXbA9ecaF5onm4k8T/3s false - sufficient binding region:1-429 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CK53 uniprotkb:Q8TF72 intact:EBI-2621010|uniprotkb:P03221|uniprotkb:Q777C8 intact:EBI-2622657|uniprotkb:Q9P247|uniprotkb:Q5QTQ3|uniprotkb:Q96IR9|uniprotkb:Q6ZRW3|ensembl:ENSP00000296043 psi-mi:cep2_ebvb9(display_long)|uniprotkb:BGLF2(orf name) psi-mi:shrm3_human(display_long)|uniprotkb:KIAA1481(gene name synonym)|uniprotkb:SHRML(gene name synonym)|uniprotkb:Shroom-related protein(gene name synonym)|uniprotkb:MSTP013(orf name)|uniprotkb:SHROOM3(gene name)|psi-mi:SHROOM3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622655|imex:IM-20435-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004286(Herpesvirus UL16/UL94)|refseq:YP_401691.1 refseq:NP_065910.3|ensembl:ENSG00000138771(gene)|ensembl:ENST00000296043(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043296"(apical junction complex)|go:"GO:0043482"(cellular pigment accumulation)|go:"GO:0045176"(apical protein localization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR014799(Apx/shroom, ASD2)|interpro:IPR014800(Apx/shroom, ASD1)|interpro:IPR027685|interpro:IPR030494|interpro:IPR036034|mint:Q8TF72|rcsb pdb:6FBB|rcsb pdb:6FCP|ensembl:ENSP00000296043 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:WSbWm8VN8ZITOLDNta3FkvoZdzE10377 rogid:0MpUunWh5c6Wwa8ep6BgurgU8e89606 intact-crc:4BC19E2777DE23AF|rigid:xWVYkMT5gOJw+Kli7vzRZUfW/hI false sufficient binding region:1-336 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C736 uniprotkb:O95681 intact:EBI-2622693 intact:EBI-2622732 psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:o95681_human(display_long)|uniprotkb:XB(gene name)|psi-mi:XB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622730|imex:IM-20435-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_061978.6|interpro:IPR036116 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 rogid:V7/bRTm7tQLtrqR2LSz0UXu7vtE9606 intact-crc:BC33931132C33870|rigid:V0cTnn89lbsYO8Areqz7o8jPcCs false sufficient binding region:1-191 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C736 uniprotkb:P02751 intact:EBI-2622693 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622721|imex:IM-20435-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2019/10/18 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 intact-crc:BC1C6CEC3738D5C4|rigid:WrzP6Qybn1NXctu/zLpQaIbLIJU false sufficient binding region:1-191 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C736 uniprotkb:A1L0V1 intact:EBI-2622693 intact:EBI-2622451 psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:a1l0v1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622712|imex:IM-20435-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 rogid:lu+3IeoAzwMY/KSxeuhvyWicesw9606 intact-crc:E56C6CF4124DA13F|rigid:lZI/ZIHuK5/E8rHP/t0kNJBgG6k false sufficient binding region:1-191 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N2S1 uniprotkb:P0C736 intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905 intact:EBI-2622693 psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short) psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622703|imex:IM-20435-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379 rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 intact-crc:D9B7FDDF8C0850EF|rigid:xv6bbtRmJLGBmU9W1DZlB1KLgao false - sufficient binding region:1-191 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03208 uniprotkb:Q9NSC5 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622761|imex:IM-20435-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:FD154529B6B2B8E8|rigid:qgse2fg6QzRgrRiRtmvXs/ssneg false sufficient binding region:1-38 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C736 uniprotkb:P04275 intact:EBI-2622693 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622752|imex:IM-20435-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 intact-crc:9C1C6D64D703084A|rigid:ugzXwdHhIOI9fCNP6WmaHUH/v84 false sufficient binding region:1-191 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:P0C736 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-2622693 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:ear_ebvg(display_long)|uniprotkb:Early antigen protein R(gene name synonym)|uniprotkb:Nuclear antigen(gene name synonym)|uniprotkb:BHRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622743|imex:IM-20435-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 rcsb pdb:2V6Q|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020726|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|interpro:IPR026298|interpro:IPR036834 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:Ti5jC8+XmhJHxeUL57wPtb8Vbas10376 intact-crc:DB289D6D094A4B9A|rigid:dr0NvHTi7vRi3NheZBjhF+yLddQ false - sufficient binding region:1-191 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03208 uniprotkb:O94813 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-1236865|uniprotkb:O95710|uniprotkb:Q17RU3|uniprotkb:Q9Y5Q7|uniprotkb:B7ZLR5|uniprotkb:A0A0A6YYB8|ensembl:ENSP00000422591 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:slit2_human(display_long)|uniprotkb:SLIT2(gene name)|psi-mi:SLIT2(display_short)|uniprotkb:SLIL3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622797|imex:IM-20435-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) refseq:NP_001276064.1|refseq:NP_001276065.1|refseq:NP_004778.1|dip:DIP-38198N|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O94813|rcsb pdb:2V70|rcsb pdb:2V9S|rcsb pdb:2V9T|rcsb pdb:2WFH|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-9010553|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|ensembl:ENSG00000145147(gene)|ensembl:ENST00000504154(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:25Wc98dEfv1yROTD5pUtyQ+LWN89606 intact-crc:E112FDC1C79952D3|rigid:1J/C1ksZ0F4XckLratEku7TvTJ0 false sufficient binding region:1-38 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03208 uniprotkb:P04275 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622788|imex:IM-20435-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 intact-crc:CE67668FF42C02F5|rigid:BsJ6wK9fvUe8L0W0Z+o93RgvT3I false sufficient binding region:1-38 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P20700 uniprotkb:P03208 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 intact:EBI-2621311|uniprotkb:Q777B2 psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622779|imex:IM-20435-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 intact-crc:9E4B79990FAAE43B|rigid:nVZ/4pYUc/FA3THsSjWq0gmcJYg false - sufficient binding region:1-38 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03208 uniprotkb:P28799 intact:EBI-2621311|uniprotkb:Q777B2 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:bilf1_ebvb9(display_long)|uniprotkb:BILF1(orf name) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622770|imex:IM-20435-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401711.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:rg04xcIAzZau/0UJU1Ths3PoPYI10377 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:8EB471CF4AB435D6|rigid:eelCmpz0ddn1GUlQRbSyzwOLmzE false sufficient binding region:1-38 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28799 uniprotkb:P03199 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 intact:EBI-2621452|uniprotkb:Q777E9 psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:bllf2_ebvb9(display_long)|uniprotkb:BLLF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622828|imex:IM-20435-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N refseq:YP_401668.1|interpro:IPR035221 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 rogid:PUFD1dey0nvc0ea8sABBzbDVTyE10377 intact-crc:DA2F76EC6D7DA5C2|rigid:luDgq9AOFSOqZqzGdnPevFm55L0 false - sufficient binding region:1-148 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:P03200 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-2622815|uniprotkb:Q777F0|uniprotkb:P03201|uniprotkb:Q66536|uniprotkb:Q66537 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:gp350_ebvb9(display_long)|uniprotkb:Membrane antigen(gene name synonym)|uniprotkb:BLLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622819|imex:IM-20435-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 interpro:IPR007796(Herpes virus major outer envelope glycoprotein)|refseq:YP_401667.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:XXioSDS6yuo1JmCWuWRVqKcVVBw10377 intact-crc:9857DE2839970657|rigid:GXqEcGYPPe7duoHLQOIu4LB7yns false - sufficient binding region:886-907 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:Q3KSS3 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-2621403 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:gl_ebvg(display_long)|uniprotkb:gL(gene name)|psi-mi:gL(display_short)|uniprotkb:BKRF2(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622806|imex:IM-20435-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 interpro:IPR034708|interpro:IPR020175|go:"GO:0016020"(membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|interpro:IPR038313 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:7zAlPU2ael0kGkn7vBOoPvR2+n810376 intact-crc:FCDA284FFC30F8C6|rigid:MQfNsmSSiuYX3/2lkrx5I4SHCH8 false - sufficient binding region:27-137 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU7 uniprotkb:Q9UHV2 intact:EBI-2622859 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 psi-mi:itp_ebvg(display_long)|uniprotkb:BOLF1(orf name) psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622872|imex:IM-20435-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034738|interpro:IPR007611(Herpes virus tegument protein U30)|go:"GO:0019033"(viral tegument)|go:"GO:0019068"(virion assembly)|go:"GO:0039701"(microtubule-dependent intracellular transport of viral material towards cell periphery)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044177"(host cell Golgi apparatus) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:aUT9+rUA3iqPYfFMP1wrAqo8l+M10376 rogid:40dvjniwxY/UQiyoVREicctpWe09606 intact-crc:DE4454128121D3D9|rigid:pXq7EYhACRqdk5LtcATk10yWPZw false sufficient binding region:1-1239 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q3KSU7 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-2622859 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:itp_ebvg(display_long)|uniprotkb:BOLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622863|imex:IM-20435-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N interpro:IPR034738|interpro:IPR007611(Herpes virus tegument protein U30)|go:"GO:0019033"(viral tegument)|go:"GO:0019068"(virion assembly)|go:"GO:0039701"(microtubule-dependent intracellular transport of viral material towards cell periphery)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044177"(host cell Golgi apparatus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:aUT9+rUA3iqPYfFMP1wrAqo8l+M10376 intact-crc:BAE6030242887189|rigid:a8jCImQFcoRYCdXCpALZ6JUXLtU false - sufficient binding region:1-1239 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28799 uniprotkb:Q69132 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 intact:EBI-2622846 psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:q69132_ebvg(display_long)|uniprotkb:BN-LF2b(gene name)|psi-mi:BN-LF2b(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622850|imex:IM-20435-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 rogid:h9k3NAbo5bNFCq+Py/cgsCixWJo10376 intact-crc:3230FC457D39CF8E|rigid:2sM5UAGCwgyG0Ez2npaphXCVQY0 false - sufficient binding region:1-95 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:P0C6Z4 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-2621475|uniprotkb:Q777F2 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:gn_ebvg(display_long)|uniprotkb:gN(gene name)|psi-mi:gN(display_short)|uniprotkb:BLRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622837|imex:IM-20435-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 interpro:IPR034707|refseq:YP_401665.1|interpro:IPR005211(UL73 viral envelope glycoprotein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0033644"(host cell membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0055036"(virion membrane) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:/r0ZmPet0XVtnS8IW92K3K2cB0k10376 intact-crc:F62B838318177BB6|rigid:lBAGE/KWpCJmZEgU20NsAFCwqyU false - sufficient binding region:33-69 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TD31 uniprotkb:Q3KSU8 intact:EBI-949834|ensembl:ENSP00000365442|ensembl:ENSP00000372832|ensembl:ENSP00000373019|ensembl:ENSP00000383205|ensembl:ENSP00000393042|ensembl:ENSP00000408012|uniprotkb:Q9NRK8|uniprotkb:Q9NWY9|uniprotkb:Q9NXJ4|uniprotkb:Q9NXK3|uniprotkb:Q9Y6W1|uniprotkb:Q9Y6W2|uniprotkb:Q5SQ82|uniprotkb:Q5STE9|uniprotkb:A2ABH6|uniprotkb:Q2TB67|uniprotkb:E9PE84 intact:EBI-2621128 psi-mi:cchcr_human(display_long)|uniprotkb:Alpha-helical coiled-coil rod protein(gene name synonym)|uniprotkb:Putative gene 8 protein(gene name synonym)|uniprotkb:CCHCR1(gene name)|psi-mi:CCHCR1(display_short)|uniprotkb:C6orf18(gene name synonym)|uniprotkb:HCR(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622881|imex:IM-20435-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000204536(gene)|ensembl:ENSG00000206355(gene)|ensembl:ENSG00000206457(gene)|ensembl:ENSG00000234114(gene)|ensembl:ENST00000376266(transcript)|ensembl:ENST00000383341(transcript)|ensembl:ENST00000383527(transcript)|ensembl:ENST00000400352(transcript)|ensembl:ENST00000416163(transcript)|ensembl:ENST00000425620(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|interpro:IPR009800(Alpha helical coiled-coil rod)|go:"GO:0005814"(centriole)|refseq:XP_016866451.1|refseq:XP_016866452.1|refseq:XP_016866453.1|refseq:XP_016866454.1|refseq:XP_016866455.1|refseq:XP_016866456.1|refseq:XP_016866457.1|refseq:NP_001099033.1|refseq:NP_001099034.1|refseq:NP_061925.2|refseq:XP_011513005.1|dip:DIP-40394N interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:wgzA1VMrSlj7h29Hpmg5L0IOAJU9606 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:20C87806940D7BB3|rigid:X/sClkkJ0YiU3zpuHoFI63eQxYo false - sufficient binding region:501-1500 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P04233 intact:EBI-2621128 intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622901|imex:IM-20435-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606 intact-crc:085A7E293DAEFE41|rigid:TGiXL6PKVaaIaxPnC2B3MgFq3BA false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49759 uniprotkb:Q3KSU8 intact:EBI-473775|uniprotkb:Q8N5V8|uniprotkb:Q0P694|intact:EBI-2622912|uniprotkb:B4DFW7|ensembl:ENSP00000326830 intact:EBI-2621128 psi-mi:clk1_human(display_long)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:CLK1(gene name)|psi-mi:CLK1(display_short)|uniprotkb:CLK(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622910|imex:IM-20435-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004062.2|refseq:NP_001155879.1|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49759|rcsb pdb:1Z57|rcsb pdb:2VAG|rcsb pdb:5J1V|rcsb pdb:5J1W|rcsb pdb:5X8I|rcsb pdb:6FT8|rcsb pdb:6FT9|rcsb pdb:6FYO|rcsb pdb:6G33|rcsb pdb:6I5H|rcsb pdb:6I5I|rcsb pdb:6I5K|rcsb pdb:6I5L|rcsb pdb:6KHD|rcsb pdb:6Q8K|rcsb pdb:6Q8P|rcsb pdb:6QTY|rcsb pdb:6R3D|rcsb pdb:6R6E|rcsb pdb:6R6X|rcsb pdb:6R8J|rcsb pdb:6RAA|rcsb pdb:6TW2|rcsb pdb:6YTA|rcsb pdb:6YTD|rcsb pdb:6YTE|rcsb pdb:6YTG|rcsb pdb:6YTI|rcsb pdb:6Z4Z|rcsb pdb:6Z50|rcsb pdb:6ZLN|rcsb pdb:7AK3|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensembl:ENSG00000013441(gene)|ensembl:ENST00000321356(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:HUyYLfLTfZHyTdtTNdbR/HPBloM9606 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:2928E3F83115062F|rigid:awrb2+UY5dTsbgJVtX9C5NrOHCw false - sufficient binding region:501-1500 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04406 uniprotkb:Q3KSU8 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 intact:EBI-2621128 psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622922|imex:IM-20435-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:096649FC1DAEFE41|rigid:H0hbHq5/RA4Qlyh+R8/sLEr2BXM false - sufficient binding region:501-1500 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P28799 intact:EBI-2621128 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622931|imex:IM-20435-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:BA21BDC095150230|rigid:syUPKrLY8ZN8NkEvhkJEjjjv3TU false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P68871 intact:EBI-2621128 intact:EBI-715554|ensembl:ENSP00000333994|ensembl:ENSP00000494175|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622940|imex:IM-20435-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 ensembl:ENSG00000244734(gene)|ensembl:ENST00000335295(transcript)|ensembl:ENST00000647020(transcript)|refseq:NP_000509.1|rcsb pdb:1XZ4|rcsb pdb:1XZ2|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:1YVT|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3HXN|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|go:"GO:0072562"(blood microparticle)|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1J3Z|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|rcsb pdb:7JY3|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:3W4U|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:4ROM|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|dip:DIP-35526N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606 intact-crc:68E9C10160E2FAD3|rigid:G6Lx5mkONC8a1vgeFB/DawnCk/o false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04439 uniprotkb:Q3KSU8 intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 intact:EBI-2621128 psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622949|imex:IM-20435-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1 interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2019/11/11 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:9A23C493E25101BE|rigid:09/ERTzV0Ohc8+7TxI3/brjdOac false - sufficient binding region:501-1500 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P01889 intact:EBI-2621128 intact:EBI-1046513|ensembl:ENSP00000399168|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622958|imex:IM-20435-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2A83|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:2AK4|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:2AXF|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:2H6P|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|interpro:IPR036179|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4G9F|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5IEK|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5IM7|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5INC|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:5T6X|rcsb pdb:6BXQ|rcsb pdb:5T6Y|rcsb pdb:6D29|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|ensembl:ENSG00000234745(gene)|ensembl:ENST00000412585(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6MTL|refseq:NP_005505.2 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2019/10/18 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606 intact-crc:EA21E7EB10B454EB|rigid:kDEpcrjaSpQu/ML300o8UotImU8 false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:Q86X95 intact:EBI-2621128 intact:EBI-627102|ensembl:ENSP00000339723|uniprotkb:A6NFI6|uniprotkb:A8K8M4|uniprotkb:O95367|uniprotkb:Q12804|uniprotkb:Q4G1B9|uniprotkb:Q6PJI4|uniprotkb:Q8IWI2 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:cir1_human(display_long)|uniprotkb:CIR(gene name synonym)|uniprotkb:CBF1-interacting corepressor(gene name synonym)|uniprotkb:Recepin(gene name synonym)|uniprotkb:CIR1(gene name)|psi-mi:CIR1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622988|imex:IM-20435-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 ensembl:ENSG00000138433(gene)|ensembl:ENST00000342016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR019339|interpro:IPR040014|mint:Q86X95|rcsb pdb:6ZYM|refseq:NP_004873.3 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:DMnBG746eQpvLsf9D+lgeUKnni09606 intact-crc:E027A2E10BF72419|rigid:dl7T2zto9Pbrz3x0sw57t1seayo false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:B3KS36 intact:EBI-2621128 intact:EBI-2622978 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:b3ks36_human(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622976|imex:IM-20435-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 interpro:IPR000597(Ribosomal protein L3)|interpro:IPR019926|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:NP_001029025.1|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:/TMXKweD4oQFTv+g/F0vfJpyajU9606 intact-crc:F966B58D1E906ECC|rigid:3AkRh8ZVQ8qoXipvDlN9ktsUDJA false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P15814 intact:EBI-2621128 intact:EBI-1222221|uniprotkb:Q0P681|ensembl:ENSP00000329312 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:igll1_human(display_long)|uniprotkb:IGLL1(gene name)|psi-mi:IGLL1(display_short)|uniprotkb:IGL1(gene name synonym)|uniprotkb:Immunoglobulin-related protein 14.1(gene name synonym)|uniprotkb:Immunoglobulin omega polypeptide(gene name synonym)|uniprotkb:Ig lambda-5(gene name synonym)|uniprotkb:CD179 antigen-like family member B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2622967|imex:IM-20435-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 refseq:NP_064455.1|refseq:NP_690594.1|ensembl:ENSG00000128322(gene)|ensembl:ENST00000330377(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P15814|rcsb pdb:2H32|rcsb pdb:2H3N|rcsb pdb:2LKQ|reactome:R-HSA-202733 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:BpOlZ3iBc9geHAdkkOm+Z5yCsiU9606 intact-crc:59D4CBDD692D389A|rigid:O1KWVUd1HiMv/cwzfErE9j1PmcQ false sufficient binding region:501-1500 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU8 uniprotkb:P80303 intact:EBI-2621128 intact:EBI-2296670|uniprotkb:D3DQX5|uniprotkb:A8K642|uniprotkb:Q8NFT5|uniprotkb:V9HW75|ensembl:ENSP00000436455|ensembl:ENSP00000481959 psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:nucb2_human(display_long)|uniprotkb:NUCB2(gene name)|psi-mi:NUCB2(display_short)|uniprotkb:NEFA(gene name synonym)|uniprotkb:DNA-binding protein NEFA(gene name synonym)|uniprotkb:Gastric cancer antigen Zg4(gene name synonym)|uniprotkb:Prepronesfatin(gene name synonym)|uniprotkb:Epididymis secretory protein Li 109(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623010|imex:IM-20435-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 refseq:NP_005004.1|refseq:XP_016873295.1|refseq:XP_016873296.1|refseq:XP_016873297.1|refseq:XP_016873298.1|refseq:XP_016873299.1|refseq:XP_016873300.1|refseq:XP_016873301.1|refseq:XP_016873302.1|refseq:XP_016873303.1|refseq:XP_016873304.1|refseq:XP_016873305.1|refseq:XP_016873306.1|refseq:XP_016873307.1|refseq:XP_016873308.1|ensembl:ENSG00000070081(gene)|ensembl:ENST00000529010(transcript)|ensembl:ENST00000622082(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028813|go:"GO:0005886"(plasma membrane)|interpro:IPR040250|mint:P80303 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2018/04/06 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 rogid:m5wJa0MtTVxrydwG9BXzjUMAlyc9606 intact-crc:18501E67A92A9E1F|rigid:V8xtNRlBVFty44gEExqW0wvo4Vs false sufficient binding region:1001-2000 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HA82 uniprotkb:Q3KSU8 intact:EBI-2622997|uniprotkb:D6W665|ensembl:ENSP00000251363|ensembl:ENSP00000453509 intact:EBI-2621128 psi-mi:cers4_human(display_long)|uniprotkb:CERS4(gene name)|psi-mi:CERS4(display_short)|uniprotkb:LASS4(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 4(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS4(gene name synonym) psi-mi:ltp_ebvg(display_long)|uniprotkb:BPLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623001|imex:IM-20435-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526592.1|refseq:XP_011526593.1|refseq:XP_011526594.1|refseq:XP_011526595.1|refseq:XP_011526596.1|refseq:XP_011526597.1|refseq:NP_078828.2|refseq:XP_016882792.1|refseq:XP_016882793.1|refseq:XP_016882794.1|ensembl:ENSG00000090661(gene)|ensembl:ENST00000251363(transcript)|ensembl:ENST00000559450(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-HSA-1660661 interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038765 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Ejt5jN6y5aCfj9LALa5XgreWVd49606 rogid:5ClvHfAqiwiSjm+QTqsNIOs0bmI10376 intact-crc:B1B197EA91FC3946|rigid:rSAuyYdZuRLzKnLNNUreYvmEGwQ false - sufficient binding region:501-1500 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C722 uniprotkb:Q9UKK3 intact:EBI-2623029|uniprotkb:Q777E3 intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419 psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:"Vault poly(ADP-ribose) polymerase"(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623019|imex:IM-20435-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699(gene)|ensembl:ENST00000381989(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042493"|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606 intact-crc:C4E51A3D0149AC70|rigid:5R/Hon094q9QBxcw2SRpg7QZuKg false sufficient binding region:1-310 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C722 uniprotkb:O15162 intact:EBI-2623029|uniprotkb:Q777E3 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623040|imex:IM-20435-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 intact-crc:13EF33E59CDB7D97|rigid:BeXDFEA4qztYblXnbvmVLiFk6E0 false sufficient binding region:1-310 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49908 uniprotkb:P0C722 intact:EBI-2623058|uniprotkb:Q6PJF9|uniprotkb:Q6PI87|uniprotkb:Q6PD59|uniprotkb:Q6PI43|ensembl:ENSP00000420939|ensembl:ENSP00000425915|ensembl:ENSP00000427671 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:sepp1_human(display_long)|uniprotkb:SELENOP(gene name)|psi-mi:SELENOP(display_short)|uniprotkb:SELP(gene name synonym)|uniprotkb:SEPP1(gene name synonym) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623066|imex:IM-20435-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078955.1|refseq:NP_005401.3|refseq:NP_001087195.1|ensembl:ENSG00000250722(gene)|ensembl:ENST00000506577(transcript)|ensembl:ENST00000511224(transcript)|ensembl:ENST00000514985(transcript)|go:"GO:0001887"(selenium compound metabolic process)|go:"GO:0005576"(extracellular region)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008430"(selenium binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019953"(sexual reproduction)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0040008"(regulation of growth)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007671(Selenoprotein P, N-terminal)|interpro:IPR007672(Selenoprotein P, C-terminal)|interpro:IPR037941|reactome:R-HSA-114608 refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:gVNS0+x+wBsjTJHheMYx9dA3yy49606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:66EC6CC3B5607385|rigid:WxaRCSwp8gbxCgudaM0m6Pr1crI false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95219 uniprotkb:P0C722 intact:EBI-724909|uniprotkb:D3DNA3|uniprotkb:B4DQV4|uniprotkb:B3KMH0|ensembl:ENSP00000251775 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:snx4_human(display_long)|uniprotkb:SNX4(gene name)|psi-mi:SNX4(display_short) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623075|imex:IM-20435-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003785.1|ensembl:ENSG00000114520(gene)|ensembl:ENST00000251775(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR034783|interpro:IPR034902|interpro:IPR036871|interpro:IPR037430|dip:DIP-36719N refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Y/Dg8VrUYYvI5Xf67D3unhCjLDA9606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:CCE1FDC50F6B3900|rigid:ZEv1O+xkOWYfH4z2Aac0bGRN704 false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12805 uniprotkb:P0C722 intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623049|imex:IM-20435-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1 refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:50374E89A23D056B|rigid:gouaEJ1oWjA70/vIVa/3nFj6Yfg false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C722 uniprotkb:Q9Y371 intact:EBI-2623029|uniprotkb:Q777E3 intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182 psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623093|imex:IM-20435-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 rogid:HSs455W45ciZL56fJSPOIvfhUIw9606 intact-crc:F7D1A1EFFF8D825D|rigid:IezsscxPBt1mrqZA2/+5nO/n25Y false sufficient binding region:1-310 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C722 uniprotkb:Q9UBX5 intact:EBI-2623029|uniprotkb:Q777E3 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623084|imex:IM-20435-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 intact-crc:213C24E75885D5D9|rigid:sx6AnD5ikyUUkfmy2Q6WiGZGuGc false sufficient binding region:1-310 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5SRE7 uniprotkb:P0C722 intact:EBI-2623130|uniprotkb:Q7Z623|uniprotkb:A6PWN9|uniprotkb:Q96GM4|uniprotkb:B4E3X8|uniprotkb:Q5SRE9|uniprotkb:Q7Z7P9|uniprotkb:B3KT57|uniprotkb:A6PWP0|uniprotkb:Q5SRF0|ensembl:ENSP00000361673 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:phyd1_human(display_long)|uniprotkb:PHYHD1(gene name)|psi-mi:PHYHD1(display_short) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623128|imex:IM-20435-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094346.1|refseq:NP_001094347.1|refseq:NP_777593.2|ensembl:ENST00000372592(transcript)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008775(Phytanoyl-CoA dioxygenase)|rcsb pdb:2OPW|rcsb pdb:3OBZ|ensembl:ENSG00000175287(gene) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:OlZX2rcC69BDgqEquF1pFxRb6dc9606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:548C41E160C58E57|rigid:dtopVMqjaTEDPIirfY7mNc4v9fA false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:P0C722 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623119|imex:IM-20435-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:158D692848A756F4|rigid:rbZBh9a7PWXb43i1yOpSGYfFyFY false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HB63 uniprotkb:P0C722 intact:EBI-743459|ensembl:ENSP00000340998|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2 intact:EBI-2623029|uniprotkb:Q777E3 psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short) psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623110|imex:IM-20435-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|ensembl:ENSG00000074527(gene)|ensembl:ENST00000343702(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043237"(laminin-1 binding)|interpro:IPR035811|reactome:R-HSA-3000171|reactome:R-HSA-373752|go:"GO:0043256"(laminin complex)|go:"GO:0060668"(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 intact-crc:74438B36DF322E1E|rigid:xNq9gQ07olJEDlcD0T1s/zk8F3g false - sufficient binding region:1-310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P19838 uniprotkb:P03193 intact:EBI-300010|ensembl:ENSP00000378297|ensembl:ENSP00000424790|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|uniprotkb:A8K5Y5|uniprotkb:B3KVE8 intact:EBI-2623150|intact:EBI-9646141|uniprotkb:Q777F5 psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:prim_ebvb9(display_long)|uniprotkb:BSLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623154|imex:IM-20435-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-448706|ensembl:ENSG00000109320(gene)|ensembl:ENST00000394820(transcript)|ensembl:ENST00000505458(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|refseq:NP_001158884.1|refseq:NP_003989.2|refseq:NP_001306155.1|dip:DIP-106N refseq:YP_401662.1|go:"GO:0003896"(DNA primase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR033685 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606 rogid:yfBTCmPba71JiFHk3UykpKgD6MQ10377 intact-crc:08FB437ADF8099E5|rigid:3FYovqgN9IAYKMgdUcTMp4/Lq84 false - sufficient binding region:1-874 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C734 uniprotkb:P62136 intact:EBI-2621388 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:btrf1_ebvg(display_long)|uniprotkb:BTRF1(orf name) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623166|imex:IM-20435-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006772(Herpesvirus BTRF1 protein) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:JMhrq+6M63yNNbXMEasFG2Z0jwg10376 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 intact-crc:545793A622C5486B|rigid:asfMNd2Mvyh1uzJt2FBFMgUYQXc false sufficient binding region:1-404 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZQ3 uniprotkb:P0C706 intact:EBI-745080|ensembl:ENSP00000294129|uniprotkb:B4DFL5|uniprotkb:Q6SPF3|uniprotkb:Q8TC10|uniprotkb:Q9UGM8|intact:EBI-957585|uniprotkb:Q6GU34 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:spn90_human(display_long)|uniprotkb:NCKIPSD(gene name)|psi-mi:NCKIPSD(display_short)|uniprotkb:AF3P21(gene name synonym)|uniprotkb:SPIN90(gene name synonym)|uniprotkb:54 kDa VacA-interacting protein(gene name synonym)|uniprotkb:54 kDa vimentin-interacting protein(gene name synonym)|uniprotkb:90 kDa SH3 protein interacting with Nck(gene name synonym)|uniprotkb:AF3p21(gene name synonym)|uniprotkb:Dia-interacting protein 1(gene name synonym)|uniprotkb:Diaphanous protein-interacting protein(gene name synonym)|uniprotkb:SH3 adapter protein SPIN90(gene name synonym)|uniprotkb:WASP-interacting SH3-domain protein(gene name synonym)|uniprotkb:Wiskott-Aldrich syndrome protein-interacting protein(gene name synonym) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623188|imex:IM-20435-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000213672(gene)|ensembl:ENST00000294129(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017022"(myosin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR001452(Src homology-3)|interpro:IPR018556|interpro:IPR030125|interpro:IPR035514|interpro:IPR036028|mint:Q9NZQ3|refseq:NP_057537.1|refseq:NP_909119.1|rcsb pdb:6DEC|rcsb pdb:6DED|rcsb pdb:6DEE|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9664422 refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:GPUSFE2sszpigAuSg81Cmk7HJCM9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:7C19700AA48B79BF|rigid:gjyMWC98Bvh8YGHTSIWwBiwUw7k false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C706 uniprotkb:Q12805 intact:EBI-2623177|uniprotkb:Q777B7 intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75 psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623175|imex:IM-20435-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606 intact-crc:A3E68F97EE78F22A|rigid:4UZuqBZYDeSpNpmBJOKiYmpDlqk false sufficient binding region:1-570 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14618 uniprotkb:P0C706 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623206|imex:IM-20435-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:F02056005FC1ACFC|rigid:nHJ+V7ZSFNsZvdoTzhES2hx9FCM false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:P0C706 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623215|imex:IM-20435-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:AD968D6E9B3A5EBA|rigid:Gyq29LxkqsMGtLRF/yxRbSfo7ns false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1L0V1 uniprotkb:P0C706 intact:EBI-2622451 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:a1l0v1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623197|imex:IM-20435-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:lu+3IeoAzwMY/KSxeuhvyWicesw9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:E897491A771A01FB|rigid:2PN2NGUssW7LZgT77gtsSpAxS/0 false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C706 uniprotkb:Q16891 intact:EBI-2623177|uniprotkb:Q777B7 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623242|imex:IM-20435-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 intact-crc:5C1971E346062DFA|rigid:phBfAty8dIfNMxyoveCEqAtVl6w false sufficient binding region:1-570 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61289 uniprotkb:P0C706 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623233|imex:IM-20435-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:61E74A10E26670DD|rigid:fy1pD16LCjUp0a08F/07U5vz+5s false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99816 uniprotkb:P0C706 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623224|imex:IM-20435-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:95CA60743EEA5E73|rigid:DDSbYIhxyDSPcZhnLEF+hRxdtH4 false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C706 uniprotkb:Q6FH22 intact:EBI-2623177|uniprotkb:Q777B7 intact:EBI-2623253 psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:q6fh22_human(display_long)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623251|imex:IM-20435-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0048251"(elastic fiber assembly)|interpro:IPR026824|interpro:IPR026823|interpro:IPR009030(Growth factor, receptor) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 rogid:pIGsLgDK0eXijN3HfQCVSbYOZUs9606 intact-crc:F774C79D98CD3244|rigid:V7gXNo//zW1QZMSzi4WEhKMpqtE false sufficient binding region:1-570 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8L6 uniprotkb:P0C706 intact:EBI-2623273|uniprotkb:Q6P2N2|uniprotkb:Q504V7|ensembl:ENSP00000361097 intact:EBI-2623177|uniprotkb:Q777B7 psi-mi:mmrn2_human(display_long)|uniprotkb:EMILIN3(gene name synonym)|uniprotkb:EMILIN-3(gene name synonym)|uniprotkb:Elastin microfibril interface located protein 3(gene name synonym)|uniprotkb:EndoGlyx-1 p125/p140 subunit(gene name synonym)|uniprotkb:MMRN2(gene name)|psi-mi:MMRN2(display_short) psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623279|imex:IM-20435-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079032.2|ensembl:ENSG00000173269(gene)|ensembl:ENST00000372027(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:oYsSqJbljAJ5tk2he6O4tSiDCn09606 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 intact-crc:73A901932EADE319|rigid:Em4T0CUkwvX2vbNGSVMg7z662QI false - sufficient binding region:1-570 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3Q8 uniprotkb:Q3KSQ2 intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9 intact:EBI-2621028 psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym) psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623288|imex:IM-20435-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1 interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 intact-crc:7A96841DB4B0DB01|rigid:ko7Jn4UfhFxi3xIwLZXzJM79/28 false - sufficient binding region:201-607 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSQ2 uniprotkb:Q5JY77 intact:EBI-2621028 intact:EBI-2514717|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934|uniprotkb:Q96LA1|uniprotkb:O43168 psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:gasp1_human(display_long)|uniprotkb:GPRASP1(gene name)|psi-mi:GPRASP1(display_short)|uniprotkb:GASP(gene name synonym)|uniprotkb:KIAA0443(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623297|imex:IM-20435-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 ensembl:ENSG00000198932(gene)|ensembl:ENST00000361600(transcript)|ensembl:ENST00000415986(transcript)|ensembl:ENST00000444152(transcript)|ensembl:ENST00000537097(transcript)|ensembl:ENST00000652542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:1990172"(G protein-coupled receptor catabolic process)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:XP_016885470.1|refseq:XP_016885471.1|refseq:NP_001092880.1|refseq:NP_001092881.1|refseq:NP_001171656.1|refseq:NP_055525.3|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 rogid:hV+EvmQTl209eBHMYEB0Pq21jYo9606 intact-crc:F272AAF4EBE163DB|rigid:fkxzd5+nJbE2CP6j47guL9rWQNc false sufficient binding region:201-607 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C706 uniprotkb:Q96EP0 intact:EBI-2623177|uniprotkb:Q777B7 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 psi-mi:cvc2_ebvg(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:BVRF1(orf name) psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623264|imex:IM-20435-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401703.1|interpro:IPR002493(Herpesvirus UL25 protein)|go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus) ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:BThFkCC+fuxJji05wSiYUIeuZrQ10376 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 intact-crc:BA2CAB6AD2D5D58C|rigid:0AIo4eGJdPQKOGNgEd6++dqK7WU false sufficient binding region:1-570 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03206 uniprotkb:Q5JY77 intact:EBI-2621186|uniprotkb:Q69127|uniprotkb:Q777E5 intact:EBI-2514717|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934|uniprotkb:Q96LA1|uniprotkb:O43168 psi-mi:bzlf1_ebvb9(display_long)|uniprotkb:Zebra(gene name synonym)|uniprotkb:BZLF1(orf name) psi-mi:gasp1_human(display_long)|uniprotkb:GPRASP1(gene name)|psi-mi:GPRASP1(display_short)|uniprotkb:GASP(gene name synonym)|uniprotkb:KIAA0443(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623337|imex:IM-20435-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5SZX|refseq:YP_401673.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR017339(Trans-activator protein BZLF1, human herpesvirus 4)|rcsb pdb:1ZSD|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2C9L|rcsb pdb:2C9N|rcsb pdb:3KWW|rcsb pdb:3KXF|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3SPV|rcsb pdb:2NX5 ensembl:ENSG00000198932(gene)|ensembl:ENST00000361600(transcript)|ensembl:ENST00000415986(transcript)|ensembl:ENST00000444152(transcript)|ensembl:ENST00000537097(transcript)|ensembl:ENST00000652542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:1990172"(G protein-coupled receptor catabolic process)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:XP_016885470.1|refseq:XP_016885471.1|refseq:NP_001092880.1|refseq:NP_001092881.1|refseq:NP_001171656.1|refseq:NP_055525.3|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:bkOXtFgnAd5I7kRzo9QRpEPmKTw10377 rogid:hV+EvmQTl209eBHMYEB0Pq21jYo9606 intact-crc:97CA2A92134FDD4B|rigid:j4jiT78KmH6/Clrll/DkHKEprUQ false sufficient binding region:1-245 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D09 uniprotkb:Q3KSQ2 intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0 intact:EBI-2621028 psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short) psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623319|imex:IM-20435-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1 interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 intact-crc:A06E9C4C298FB893|rigid:XpuwAQ7QV/nKEZDdF7YVeS4USLg false - sufficient binding region:201-607 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSQ2 uniprotkb:Q16206 intact:EBI-2621028 intact:EBI-744159|uniprotkb:Q5VTJ1|uniprotkb:Q5VTJ2|uniprotkb:Q8WUX0|uniprotkb:Q9NTP6|uniprotkb:Q9UH82|intact:EBI-2623308|uniprotkb:A8K197|uniprotkb:A8K1C2|ensembl:ENSP00000337146|ensembl:ENSP00000359965 psi-mi:kith_ebvg(display_long)|uniprotkb:BXLF1(orf name)|uniprotkb:TK(gene name)|psi-mi:TK(display_short) psi-mi:enox2_human(display_long)|uniprotkb:Tumor-associated hydroquinone oxidase(gene name synonym)|uniprotkb:Cytosolic ovarian carcinoma antigen 1(gene name synonym)|uniprotkb:APK1 antigen(gene name synonym)|uniprotkb:ENOX2(gene name)|psi-mi:ENOX2(display_short)|uniprotkb:COVA1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623306|imex:IM-20435-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001889(Herpesvirus thymidine kinase)|interpro:IPR013672(Herpesvirus thymidine kinase, C-terminal)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006230"(TMP biosynthetic process)|go:"GO:0019033"(viral tegument)|go:"GO:0042025"(host cell nucleus)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR027417 refseq:NP_006366.2|refseq:NP_872114.1|refseq:XP_011529549.1|refseq:XP_011529551.1|refseq:XP_011529553.1|refseq:NP_001268665.1|refseq:XP_005262411.1|mint:Q16206|interpro:IPR038876|ensembl:ENST00000338144(transcript)|ensembl:ENST00000370927(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0022900"(electron transport chain)|go:"GO:0040008"(regulation of growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034140|interpro:IPR035979|ensembl:ENSG00000165675(gene)|refseq:XP_016884715.1|refseq:XP_016884716.1|refseq:XP_016884717.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:kMFU/PjYdWdVbriDlgcH69I3py410376 rogid:nqvZJv5GYe49nv+r4Bda6aRZ/mU9606 intact-crc:2ECEABC9D3A3E4A7|rigid:lnvi+ZREa9qD6q4Vt12LZp0/uh0 false sufficient binding region:201-607 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBX5 uniprotkb:P03232 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 intact:EBI-2621513|uniprotkb:Q777B8 psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:ul24_ebvb9(display_long)|uniprotkb:BXRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623328|imex:IM-20435-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 refseq:YP_401702.1|interpro:IPR002580(Herpes virus protein UL24)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044196"(host cell nucleolus) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 rogid:WsCdJejq1HJmTw/CdzfUSVjRFKM10377 intact-crc:639220A3B5A45799|rigid:nb/xU74GicE+4kQxcSk5qEkdtLs false - sufficient binding region:1-248 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSS4 uniprotkb:Q99750 intact:EBI-2621046 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623376|imex:IM-20435-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:1DEEB43D677DB8AD|rigid:0u51G+ADkGwhDboKgmP+RfJJY2s false sufficient binding region:320-386 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16206 uniprotkb:P03206 intact:EBI-744159|uniprotkb:Q5VTJ1|uniprotkb:Q5VTJ2|uniprotkb:Q8WUX0|uniprotkb:Q9NTP6|uniprotkb:Q9UH82|intact:EBI-2623308|uniprotkb:A8K197|uniprotkb:A8K1C2|ensembl:ENSP00000337146|ensembl:ENSP00000359965 intact:EBI-2621186|uniprotkb:Q69127|uniprotkb:Q777E5 psi-mi:enox2_human(display_long)|uniprotkb:Tumor-associated hydroquinone oxidase(gene name synonym)|uniprotkb:Cytosolic ovarian carcinoma antigen 1(gene name synonym)|uniprotkb:APK1 antigen(gene name synonym)|uniprotkb:ENOX2(gene name)|psi-mi:ENOX2(display_short)|uniprotkb:COVA1(gene name synonym) psi-mi:bzlf1_ebvb9(display_long)|uniprotkb:Zebra(gene name synonym)|uniprotkb:BZLF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623346|imex:IM-20435-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006366.2|refseq:NP_872114.1|refseq:XP_011529549.1|refseq:XP_011529551.1|refseq:XP_011529553.1|refseq:NP_001268665.1|refseq:XP_005262411.1|mint:Q16206|interpro:IPR038876|ensembl:ENST00000338144(transcript)|ensembl:ENST00000370927(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0022900"(electron transport chain)|go:"GO:0040008"(regulation of growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034140|interpro:IPR035979|ensembl:ENSG00000165675(gene)|refseq:XP_016884715.1|refseq:XP_016884716.1|refseq:XP_016884717.1 rcsb pdb:5SZX|refseq:YP_401673.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR017339(Trans-activator protein BZLF1, human herpesvirus 4)|rcsb pdb:1ZSD|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2C9L|rcsb pdb:2C9N|rcsb pdb:3KWW|rcsb pdb:3KXF|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019046"(release from viral latency)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3SPV|rcsb pdb:2NX5 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:nqvZJv5GYe49nv+r4Bda6aRZ/mU9606 rogid:bkOXtFgnAd5I7kRzo9QRpEPmKTw10377 intact-crc:4BA79C4B3917D6B8|rigid:7cAgzsuySOhXSZGyGdCs1VmdiTc false - sufficient binding region:1-245 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07021 uniprotkb:Q3KSS4 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 intact:EBI-2621046 psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623367|imex:IM-20435-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:758C52DADCBA7CD5|rigid:E6IIQVpOUbTzKtB5UuqYbGGTqRU false - sufficient binding region:320-386 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69114 uniprotkb:P28799 intact:EBI-2623355 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:q69114_ebvg(display_long) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623358|imex:IM-20435-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:SuWNzNh9F1rNPvVvnE1JlDEgkMI10376 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:D6A121FD4004960A|rigid:N0mleCXtj7+J7NWAYJAOq1i0P/o false sufficient binding region:1-57 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q3KSV2 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-633374 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623412|imex:IM-20435-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 intact-crc:12A05C9CA78F6B98|rigid:K/w+cJlBfsJUMuONIRXDGe7z7ic false - sufficient binding region:59-448 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRD5 uniprotkb:Q3KSS4 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-2621046 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623394|imex:IM-20435-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:D7AC8EB397DEA12A|rigid:S/g5AKuopYF+A88s1ozgzIt6zFo false - sufficient binding region:379-641 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52292 uniprotkb:Q3KSS4 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 intact:EBI-2621046 psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623385|imex:IM-20435-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:E2228214CD78BE14|rigid:bSjXwzmH/wvsb3sQDAtug5HfE8I false - sufficient binding region:379-641 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99816 uniprotkb:Q3KSS4 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 intact:EBI-2621046 psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:ebna1_ebvg(display_long)|uniprotkb:EBNA1(gene name)|psi-mi:EBNA1(display_short)|uniprotkb:BKRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623403|imex:IM-20435-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 rcsb pdb:4PRH|interpro:IPR004186(Epstein Barr virus nuclear antigen-1, DNA-binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0019042"(viral latency)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:4PR5|rcsb pdb:4PRD|interpro:IPR035975|interpro:IPR037007|rcsb pdb:5T7X - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 rogid:w9lSwKRJZ/XsIOmq6ekofw+l6dY10376 intact-crc:716B83273E97C001|rigid:Fd/5ZPM/kED9L8Jfyp1j65wFRR4 false - sufficient binding region:387-641 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43866 uniprotkb:Q3KSV2 intact:EBI-2623436|uniprotkb:A8K7M5|uniprotkb:Q6UX63|ensembl:ENSP00000357156 intact:EBI-633374 psi-mi:cd5l_human(display_long)|uniprotkb:API6(gene name synonym)|uniprotkb:CT-2(gene name synonym)|uniprotkb:IgM-associated peptide(gene name synonym)|uniprotkb:SP-alpha(gene name synonym)|uniprotkb:UNQ203/PRO229(orf name)|uniprotkb:Apoptosis inhibitor expressed by macrophages(gene name synonym)|uniprotkb:CD5L(gene name)|psi-mi:CD5L(display_short) psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623434|imex:IM-20435-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001334627.1|refseq:NP_005885.1|ensembl:ENSG00000073754(gene)|ensembl:ENST00000368174(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0009986"(cell surface)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031638"(zymogen activation)|go:"GO:0072562"(blood microparticle)|go:"GO:1903661"(positive regulation of complement-dependent cytotoxicity)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772 go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:g+Yen5g8QKKkkcmIVSd0eylQJYg9606 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 intact-crc:E895A23AFD1F2F71|rigid:tDjbIumx/+75ntvSW5znqU9N1ek false - sufficient binding region:59-448 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSV2 uniprotkb:Q8WY48 intact:EBI-633374 intact:EBI-2623423 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:q8wy48_human(display_long)|uniprotkb:PP2150(gene name)|psi-mi:PP2150(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623421|imex:IM-20435-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:EzVGt3TxWENaD6NB3jtT8ZyZw3A9606 intact-crc:BC4E2E2601C6AFF4|rigid:w1feEfORdOAQYgYjsTOCsA8kW00 false sufficient binding region:59-448 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSV2 uniprotkb:P15529 intact:EBI-633374 intact:EBI-2623451|uniprotkb:A0T1T0|uniprotkb:A0T1T1|uniprotkb:Q9UCJ4|uniprotkb:Q5VWS7|uniprotkb:Q5VWT1|uniprotkb:Q7Z3R5|uniprotkb:Q9NNW2|uniprotkb:Q6N0A1|uniprotkb:Q5VWS6|uniprotkb:Q5VWS8|uniprotkb:A0T1T2|uniprotkb:Q9NNW3|uniprotkb:Q5HY94|uniprotkb:Q5VWS9|uniprotkb:Q53GV9|uniprotkb:Q15429|uniprotkb:Q9NNW4|uniprotkb:Q5VWT0|uniprotkb:Q5VWT2|ensembl:ENSP00000350893 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:mcp_human(display_long)|uniprotkb:MCP(gene name synonym)|uniprotkb:MIC10(gene name synonym)|uniprotkb:TLX(gene name synonym)|uniprotkb:Trophoblast leukocyte common antigen(gene name synonym)|uniprotkb:CD46(gene name)|psi-mi:CD46(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623449|imex:IM-20435-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:XP_011507865.1|refseq:XP_011507866.1|refseq:NP_002380.3|refseq:NP_722548.1|refseq:NP_758860.1|refseq:NP_758861.1|refseq:NP_758862.1|refseq:NP_758863.1|refseq:NP_758869.1|refseq:NP_758871.1|refseq:XP_016856797.1|refseq:XP_016856798.1|refseq:XP_016856799.1|ensembl:ENSG00000117335(gene)|ensembl:ENST00000358170(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0007338"(single fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0035581"(sequestering of extracellular ligand from receptor)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045959"(negative regulation of complement activation, classical pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR017341(Membrane cofactor protein, CD46)|interpro:IPR035976|rcsb pdb:1CKL|rcsb pdb:1HR4|rcsb pdb:2O39|rcsb pdb:3INB|rcsb pdb:3L89|rcsb pdb:3O8E|rcsb pdb:5FO8|reactome:R-HSA-977606|dip:DIP-41232N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:nhB+pnkhLRsOA01ekJ50pkUu3og9606 intact-crc:EF29329D52FCAA40|rigid:PbYjdiSWdx1wBWIDlqkI4na5ZnY false sufficient binding region:59-448 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30626 uniprotkb:Q3KSV2 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 intact:EBI-633374 psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623498|imex:IM-20435-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - crc64:A4829C7650A5E3FA - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 intact-crc:D3CD392C266E7D1B|rigid:MuOmMKMjMlDvnIpyR8WBRa9kZwg false - sufficient binding region:59-448 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15326 uniprotkb:Q3KSV2 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-633374 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623507|imex:IM-20435-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 intact-crc:FD79F65D2DE5AFA5|rigid:igONihXA9EpyD2i8VbLJRI4yNSQ false - sufficient binding region:59-448 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSV2 uniprotkb:P09455 intact:EBI-633374 intact:EBI-2623483|ensembl:ENSP00000482165|intact:EBI-3933584|uniprotkb:B7Z7A0|uniprotkb:E7EWV0|uniprotkb:F2Z2F2|uniprotkb:Q6FGX8|uniprotkb:A8K2Q0 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:ret1_human(display_long)|uniprotkb:RBP1(gene name)|psi-mi:RBP1(display_short)|uniprotkb:CRBP1(gene name synonym)|uniprotkb:Cellular retinol-binding protein(gene name synonym)|uniprotkb:Cellular retinol-binding protein I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623481|imex:IM-20435-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_001124465.1|ensembl:ENSG00000114115(gene)|ensembl:ENST00000619087(transcript)|go:"GO:0002138"(retinoic acid biosynthetic process)|go:"GO:0005501"(retinoid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006776"(vitamin A metabolic process)|go:"GO:0016918"(retinal binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:1904768"(all-trans-retinol binding)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|interpro:IPR031264|mint:P09455|rcsb pdb:5H8T|rcsb pdb:5H9A|rcsb pdb:5HA1|rcsb pdb:5HBS|rcsb pdb:5LJB|rcsb pdb:5LJC|rcsb pdb:5LJD|rcsb pdb:5LJE|rcsb pdb:5LJG|rcsb pdb:5LJH|rcsb pdb:5LJK|rcsb pdb:6E5L|rcsb pdb:6E5T|rcsb pdb:6E6M|reactome:R-HSA-2453864|reactome:R-HSA-2453902|reactome:R-HSA-975634|refseq:NP_002890.2|refseq:NP_001124464.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:QxKuGge3qk7Q9lmPxlKV112cdBc9606 intact-crc:273B187AFF3D1923|rigid:GfGg6sttvtgjnzxJBUXuu6ZGMZA false sufficient binding region:59-448 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:Q9UBX5 intact:EBI-2623552 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623556|imex:IM-20435-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 intact-crc:FB4A13A9A487C1BB|rigid:iZxMjtOYBBKPPOiI5NOxuPu3LBc false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSV2 uniprotkb:Q86WN1 intact:EBI-633374 intact:EBI-2623537|uniprotkb:Q6UX75|uniprotkb:Q86Y77|uniprotkb:Q9NXX8|ensembl:ENSP00000399259 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:fcsd1_human(display_long)|uniprotkb:FCHSD1(gene name)|psi-mi:FCHSD1(display_short)|uniprotkb:Protein nervous wreck 2(gene name synonym)|uniprotkb:UNQ737/PRO1431(orf name) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623535|imex:IM-20435-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_258260.1|ensembl:ENSG00000197948(gene)|ensembl:ENST00000435817(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008289"(lipid binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032437"(cuticular plate)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR034935|interpro:IPR035460|interpro:IPR036028 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:sMaYCV8xaZ7qSTKQi2+opZq0ano9606 intact-crc:CAA9C4578777E63D|rigid:KXicDAUcwgulXldoE84k39ulsdg false sufficient binding region:59-448 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSV2 uniprotkb:Q8WV28 intact:EBI-633374 intact:EBI-2623522|uniprotkb:O75498|uniprotkb:O75499|ensembl:ENSP00000224337|uniprotkb:Q2MD49 psi-mi:ebna2_ebvg(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:blnk_human(display_long)|uniprotkb:BASH(gene name synonym)|uniprotkb:SLP65(gene name synonym)|uniprotkb:B-cell adapter containing a SH2 domain protein(gene name synonym)|uniprotkb:B-cell adapter containing a Src homology 2 domain protein(gene name synonym)|uniprotkb:Cytoplasmic adapter protein(gene name synonym)|uniprotkb:Src homology 2 domain-containing leukocyte protein of 65 kDa(gene name synonym)|uniprotkb:BLNK(gene name)|psi-mi:BLNK(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623520|imex:IM-20435-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_001107566.1|refseq:NP_037446.1|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q8WV28|rcsb pdb:6YLU|reactome:R-HSA-912631|reactome:R-HSA-983695|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000095585(gene)|ensembl:ENST00000224337(transcript)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|refseq:NP_001245369.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+d6IRVpcOnYgI45XAh028g6gqnY10376 rogid:befGiho6PlVSSMPyb84d31TT/So9606 intact-crc:35E82C8D5C1A06EB|rigid:Dy5bX9NgBHf02e5yqO/zPtEm96E false sufficient binding region:59-448 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:Q13185 intact:EBI-2623552 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623565|imex:IM-20435-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:6C85D422D0D465EA|rigid:Ky/Uo9p5xvq2I7GZBow7a4afkEc false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:P28676 intact:EBI-2623552 intact:EBI-947242|uniprotkb:Q53TB5|uniprotkb:Q59EP3|uniprotkb:B2R5X3|ensembl:ENSP00000394842 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:gran_human(display_long)|uniprotkb:GCA(gene name)|psi-mi:GCA(display_short)|uniprotkb:GCL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623601|imex:IM-20435-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_036330.1|dip:DIP-41437N|ensembl:ENSG00000115271(gene)|ensembl:ENST00000437150(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1F4O|rcsb pdb:1F4Q|rcsb pdb:1K94|rcsb pdb:1K95|reactome:R-HSA-6798695 - - crc64:88CA4DDF835AFFE4 figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:I1zdQPwDUFrBGazaVREgC7nqxok9606 intact-crc:3BA5546A33FE79C0|rigid:aIG1ORG2/q8gbO2wA2jiHq/FEmk false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:P63167 intact:EBI-2623552 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623583|imex:IM-20435-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:1999C13F66C946C1|rigid:i8z9homH3bZ7sHrz5mw0BKTmlG0 false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95967 uniprotkb:Q69022 intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295 intact:EBI-2623552 psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name) psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623574|imex:IM-20435-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 intact-crc:EE3D68340B7F9EBD|rigid:qoMfdAt6V2nihL4uCa0D5su2CXE false - sufficient binding region:73-454 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76013 uniprotkb:Q69022 intact:EBI-1054946|uniprotkb:Q86XG4|ensembl:ENSP00000329165 intact:EBI-2623552 psi-mi:krt36_human(display_long)|uniprotkb:KRTHA6(gene name synonym)|uniprotkb:Hair keratin, type I Ha6(gene name synonym)|uniprotkb:Keratin-36(gene name synonym)|uniprotkb:KRT36(gene name)|psi-mi:KRT36(display_short)|uniprotkb:HHA6(gene name synonym)|uniprotkb:HKA6(gene name synonym) psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623592|imex:IM-20435-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003762.1|ensembl:ENSG00000126337(gene)|ensembl:ENST00000328119(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:T3L08n7jEhsouGDkQuK0jBLanBQ9606 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 intact-crc:104E9D615FA3C366|rigid:l2I6vCdbfIT38KoiuoY85fq9+IY false - sufficient binding region:73-454 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:B3KR20 intact:EBI-2623552 intact:EBI-2623621 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:b3kr20_human(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623619|imex:IM-20435-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_060661.3 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:r+FyQtR5painH6b3p0Kl4/7zB0s9606 intact-crc:14B271B2D13D8538|rigid:TATEhvNnDGxroeMN/IjBoTROUf4 false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KST2 uniprotkb:P22736 intact:EBI-2621171 intact:EBI-721550|uniprotkb:B4DML7|ensembl:ENSP00000243050|ensembl:ENSP00000378301|ensembl:ENSP00000378302|uniprotkb:Q15627|uniprotkb:Q53Y00|uniprotkb:Q6IBU8 psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:nr4a1_human(display_long)|uniprotkb:Orphan nuclear receptor HMR(gene name synonym)|uniprotkb:Early response protein NAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR3(gene name synonym)|uniprotkb:ST-59(gene name synonym)|uniprotkb:GFRP1(gene name synonym)|uniprotkb:HMR(gene name synonym)|uniprotkb:NAK1(gene name synonym)|uniprotkb:NR4A1(gene name)|psi-mi:NR4A1(display_short)|uniprotkb:Nuclear hormone receptor NUR/77(gene name synonym)|uniprotkb:Testicular receptor 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623631|imex:IM-20435-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 refseq:NP_001189162.1|refseq:NP_002126.2|refseq:NP_775180.1|ensembl:ENSG00000123358(gene)|ensembl:ENST00000243050(transcript)|ensembl:ENST00000394824(transcript)|ensembl:ENST00000394825(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|dip:DIP-40392N|refseq:XP_005268881.1|refseq:XP_006719426.1|refseq:XP_006719427.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014860"(neurotransmitter secretion involved in regulation of skeletal muscle contraction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0098793"(presynapse)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003071(Orphan nuclear receptor, HMR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P22736|rcsb pdb:2QW4|rcsb pdb:3V3E|rcsb pdb:3V3Q|rcsb pdb:4JGV|rcsb pdb:4KZI|rcsb pdb:4KZJ|rcsb pdb:4KZM|rcsb pdb:4RE8|rcsb pdb:4REE|rcsb pdb:4REF|rcsb pdb:4RZE|rcsb pdb:4RZF|rcsb pdb:4RZG|rcsb pdb:4WHF|rcsb pdb:4WHG|rcsb pdb:6KZ5|rcsb pdb:6LC1|reactome:R-HSA-198693|reactome:R-HSA-383280|reactome:R-HSA-5674400 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 rogid:yocf+C94vprIeNXXB89p3tqzW/c9606 intact-crc:1C3AC9B3E314653B|rigid:YQbc4RvLjHo754u9nuoRWco1ejA false sufficient binding region:1-300 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36578 uniprotkb:Q3KST2 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 intact:EBI-2621171 psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623640|imex:IM-20435-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376 intact-crc:73D52CF865B86526|rigid:TGEzjjqmEkDbzYDufgBfgnhc0Xk false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69022 uniprotkb:Q9Y371 intact:EBI-2623552 intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182 psi-mi:ebna2_ebva8(display_long)|uniprotkb:BYRF1(orf name)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short) psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:82830(ebva8)|taxid:82830("Epstein-Barr virus (strain AG876) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623610|imex:IM-20435-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_001129441.1|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0060153"(modulation by virus of host cell cycle) refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:w++IJd9en1tV2ezVwfP14p+thrQ82830 rogid:HSs455W45ciZL56fJSPOIvfhUIw9606 intact-crc:2DA796A1038F963F|rigid:251kHNIen0vRCXpkMGuXuOr6AmY false sufficient binding region:73-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69139 uniprotkb:O43707 intact:EBI-2621446 intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467 psi-mi:q69139_ebvg(display_long) psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623676|imex:IM-20435-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606 intact-crc:14B63308B267059C|rigid:6FFFzVt6Zi9Lg2h1ICkYXRPIqpM false sufficient binding region:741-938 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69139 uniprotkb:P25788 intact:EBI-2621446 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:q69139_ebvg(display_long) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623658|imex:IM-20435-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:B5489574DEFC319C|rigid:3H4hAQ7uKICaRRndGvMa6incltU false sufficient binding region:601-900 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15942 uniprotkb:Q69139 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 intact:EBI-2621446 psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:q69139_ebvg(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623649|imex:IM-20435-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 intact-crc:6166EB6212F75070|rigid:c6ZTYmDOtoy8OHTvCgQZsQE6VAA false - sufficient binding region:451-750 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y371 uniprotkb:Q69139 intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182 intact:EBI-2621446 psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short) psi-mi:q69139_ebvg(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623667|imex:IM-20435-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:HSs455W45ciZL56fJSPOIvfhUIw9606 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 intact-crc:729DF020F25F67F5|rigid:bohG2Tjog85m6dvAgqls3N/rT2M false - sufficient binding region:601-900 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69139 uniprotkb:A1L0V1 intact:EBI-2621446 intact:EBI-2622451 psi-mi:q69139_ebvg(display_long) psi-mi:a1l0v1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623685|imex:IM-20435-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016032"(viral process)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|dip:DIP-707N interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:XhGlxhM8SWkPzPP72hdu0w1R2vQ10376 rogid:lu+3IeoAzwMY/KSxeuhvyWicesw9606 intact-crc:F07978C3E192519C|rigid:LmoqmR8JVhdzS4SULSR6IMKdl6M false sufficient binding region:741-938 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBX5 uniprotkb:Q69119 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:q69119_ebvg(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623694|imex:IM-20435-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 intact-crc:74CD7421B9DB339D|rigid:RnXweyW24Fl3hioYzPlFEyDI+DY false - sufficient binding region:751-992 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q69119 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:q69119_ebvg(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623703|imex:IM-20435-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 intact-crc:002CE111BA88EDBF|rigid:33FVL/u80fFhgAtyVX4fLGiBBZ8 false - sufficient binding region:601-900 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C732 uniprotkb:P25788 intact:EBI-2623732 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:ebna5_ebvg(display_long)|uniprotkb:EBNA5(gene name synonym)|uniprotkb:Epstein-Barr nuclear antigen 5(gene name synonym)|uniprotkb:EBNA-LP(gene name)|psi-mi:EBNA-LP(display_short) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623730|imex:IM-20435-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401636.1|interpro:IPR005030(Herpesvirus leader protein)|go:"GO:0042025"(host cell nucleus) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+R0vA4FqPHMXIdCOlme2SdSU5To10376 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:64D3D3668C3AD912|rigid:5SXH2DL7Move/iX99xXfe0od/6g false sufficient binding region:462-506 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69119 uniprotkb:P04275 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405 psi-mi:q69119_ebvg(display_long) psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623721|imex:IM-20435-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606 intact-crc:3A4E5D9A46F9285B|rigid:Vqa/rR7RqT3SA9UtHyIB5d5cofo false sufficient binding region:601-900 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q69119 uniprotkb:P49908 intact:EBI-2621244|uniprotkb:Q69120|uniprotkb:Q69121 intact:EBI-2623058|uniprotkb:Q6PJF9|uniprotkb:Q6PI87|uniprotkb:Q6PD59|uniprotkb:Q6PI43|ensembl:ENSP00000420939|ensembl:ENSP00000425915|ensembl:ENSP00000427671 psi-mi:q69119_ebvg(display_long) psi-mi:sepp1_human(display_long)|uniprotkb:SELENOP(gene name)|psi-mi:SELENOP(display_short)|uniprotkb:SELP(gene name synonym)|uniprotkb:SEPP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623712|imex:IM-20435-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process) refseq:NP_001078955.1|refseq:NP_005401.3|refseq:NP_001087195.1|ensembl:ENSG00000250722(gene)|ensembl:ENST00000506577(transcript)|ensembl:ENST00000511224(transcript)|ensembl:ENST00000514985(transcript)|go:"GO:0001887"(selenium compound metabolic process)|go:"GO:0005576"(extracellular region)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008430"(selenium binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019953"(sexual reproduction)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0040008"(regulation of growth)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007671(Selenoprotein P, N-terminal)|interpro:IPR007672(Selenoprotein P, C-terminal)|interpro:IPR037941|reactome:R-HSA-114608 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:aLM+k3x960rinyXKNatu4MYqw2410376 rogid:gVNS0+x+wBsjTJHheMYx9dA3yy49606 intact-crc:2850CA86D3AC7FF5|rigid:mlSVDNEcuABAJmLi2itzsHujtMs false sufficient binding region:601-900 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHF1 uniprotkb:A8CSJ8 intact:EBI-949532|ensembl:ENSP00000307843|ensembl:ENSP00000360763|ensembl:ENSP00000360764|ensembl:ENSP00000385639|uniprotkb:Q5M7Y5|uniprotkb:Q5VUD5|uniprotkb:Q96EG0|uniprotkb:B3KRP0|uniprotkb:M9VTX9 intact:EBI-2621399 psi-mi:egfl7_human(display_long)|uniprotkb:Multiple epidermal growth factor-like domains protein 7(gene name synonym)|uniprotkb:Zneu1(gene name synonym)|uniprotkb:Vascular endothelial statin(gene name synonym)|uniprotkb:NOTCH4-like protein(gene name synonym)|uniprotkb:EGFL7(gene name)|psi-mi:EGFL7(display_short)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:UNQ187/PRO1449(orf name) psi-mi:a8csj8_ebvg(display_long)|uniprotkb:LMP1(gene name)|psi-mi:LMP1(display_short)|uniprotkb:Protein p63(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623743|imex:IM-20435-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172889(gene)|ensembl:ENST00000308874(transcript)|ensembl:ENST00000371698(transcript)|ensembl:ENST00000371699(transcript)|ensembl:ENST00000406555(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018097|mint:Q9UHF1|go:"GO:0005576"(extracellular region)|refseq:NP_057299.1|refseq:NP_958854.1|refseq:XP_011517066.1|refseq:XP_011517067.1|refseq:XP_011517068.1 interpro:IPR007961(Herpesvirus latent membrane 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:HzaJXQm4JE8bXXE+/ugmqGjpjZA9606 rogid:IauQJufSPe5FO50gNY6vEY8pZlo10376 intact-crc:7DE0E0E6F1EEC678|rigid:Bb8v1RhHFLJM8VCbNcZojFSOmdg false - sufficient binding region:232-386 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU1 uniprotkb:Q15691 intact:EBI-2621113|uniprotkb:Q3KSU0 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623761|imex:IM-20435-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 intact-crc:131931C481E39DD6|rigid:/Tb72A2QcXHdB0Cy8rIYaaO3bmc false sufficient binding region:1-479 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62995 uniprotkb:Q3KSU1 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 intact:EBI-2621113|uniprotkb:Q3KSU0 psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623770|imex:IM-20435-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 intact-crc:571676D3489E826D|rigid:tEtPpQ2YAHhAwLZyVyFDQ7lpG5g false - sufficient binding region:42-479 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU1 uniprotkb:Q68DS7 intact:EBI-2621113|uniprotkb:Q3KSU0 intact:EBI-2623779 psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:q68ds7_human(display_long)|uniprotkb:DKFZp686E07254(gene name)|psi-mi:DKFZp686E07254(display_short) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623783|imex:IM-20435-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) interpro:IPR043563|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR001487(Bromodomain)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR019786|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036427 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 rogid:6ZozVTKHNtOoOvxNDR7USh5UCP89606 intact-crc:B41F029BB0848C5E|rigid:uCB/uBgfCozCrv/3MExh2lUKszA false sufficient binding region:42-479 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C729 uniprotkb:Q08380 intact:EBI-2621229 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:lmp2_ebvg(display_long)|uniprotkb:Terminal protein(gene name synonym)|uniprotkb:LMP2(gene name)|psi-mi:LMP2(display_short) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623752|imex:IM-20435-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010881(Gammaherpesvirus latent membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019042"(viral latency) ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:Gld4/oda4Ub+/x4OO1LviqFMZmw10376 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:F5A28ECC07380306|rigid:ih4u4sT+c9GpOAlJAYeqGKS1CtM false sufficient binding region:1-119 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3KSU1 intact:EBI-2623792 intact:EBI-2621113|uniprotkb:Q3KSU0 - psi-mi:icp27_ebvg(display_long)|uniprotkb:Protein SM(gene name synonym)|uniprotkb:Mta(gene name synonym)|uniprotkb:BSLF2(orf name)|uniprotkb:BMLF1(orf name)|uniprotkb:ORF57 protein homolog(gene name synonym) psi-mi:gg6l8_human(display_short)|psi-mi:EBI-2623792(display_long) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2623795|imex:IM-20435-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008648(Herpesvirus transcriptional regulator)|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3O4L|go:"GO:0003723"(RNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport) uniprotkb:Q8N824(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:NcjS1dzNt6QLZlFkJ02pxVA8Nz010376 rogid:8CnAoMoViy6wGsXM/DIcoH7l2Us9606 intact-crc:7018615E6E63A4B4|rigid:XwOZsXvYVormJJIKIpi50Kctcko false sufficient binding region:42-479 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C722 uniprotkb:Q12933 intact:EBI-2623029|uniprotkb:Q777E3 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:brrf1_ebvg(display_long)|uniprotkb:BRRF1(orf name) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Calderwood et al. (2007) pubmed:17446270|imex:IM-20435|mint:MINT-6769080 taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2644156|imex:IM-20435-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401675.1|interpro:IPR006878(BRRF1-like protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N - - - figure legend:supplemental table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/22 2014/10/16 rogid:+rTQ2y+ClZbRPGZEV/JiJFtEGoA10376 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:067C0F1C20D3C594|rigid:fHm6Oh/9mzi0z3KRq96tgEhK/0Y false sufficient binding region:1-310 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)