#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31946 uniprotkb:P22893 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 intact:EBI-647803|uniprotkb:P11520|ensembl:ENSMUSP00000057815 psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:ttp_mouse(display_long)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:TPA-induced sequence 11(gene name synonym)|uniprotkb:Zfp36(gene name)|psi-mi:Zfp36(display_short)|uniprotkb:Tis11(gene name synonym)|uniprotkb:Tis11a(gene name synonym)|uniprotkb:Nup475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Ttp(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Sun et al. (2007) pubmed:17170118|mint:MINT-8007706|doi:10.1074/jbc.M607347200 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7168233|mint:MINT-8007715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-8007716(identity)|uniprotkb:P31946(original identifier) refseq:NP_035886.1|ensembl:ENSMUSG00000044786(gene)|ensembl:ENSMUST00000051241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050779"(RNA destabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:1M9O|reactome:R-MMU-450513|mint:MINT-8007719(identity)|uniprotkb:P22893(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rogid:cqk/T7+rfnB3UkeawYWXFkx1VfM10090 intact-crc:BCD1BFE36BD6B2A4|rigid:eNkp3iRtXrR+7/8KnO+qwds68j4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31946 uniprotkb:P22893 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 intact:EBI-647803|uniprotkb:P11520|ensembl:ENSMUSP00000057815 psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:ttp_mouse(display_long)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:TPA-induced sequence 11(gene name synonym)|uniprotkb:Zfp36(gene name)|psi-mi:Zfp36(display_short)|uniprotkb:Tis11(gene name synonym)|uniprotkb:Tis11a(gene name synonym)|uniprotkb:Nup475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Ttp(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Sun et al. (2007) pubmed:17170118|mint:MINT-8007706|doi:10.1074/jbc.M607347200 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7168246|mint:MINT-8007722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-8007723(identity)|uniprotkb:P31946(original identifier) refseq:NP_035886.1|ensembl:ENSMUSG00000044786(gene)|ensembl:ENSMUST00000051241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050779"(RNA destabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:1M9O|reactome:R-MMU-450513|mint:MINT-8007726(identity)|uniprotkb:P22893(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rogid:cqk/T7+rfnB3UkeawYWXFkx1VfM10090 intact-crc:733D20C7F457937F|rigid:eNkp3iRtXrR+7/8KnO+qwds68j4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)