#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q0G819 uniprotkb:Q21017 intact:EBI-323063|intact:EBI-2412118|intact:EBI-7683011|intact:MINT-3383953|uniprotkb:Q86MD4|uniprotkb:Q95002|ensemblmetazoa:C02F4.2b.1|ensemblmetazoa:C02F4.2c.1 intact:EBI-2893174|ensemblmetazoa:F58H12.1.1 psi-mi:pp2b_caeel(display_long)|uniprotkb:tax-6(gene name)|psi-mi:tax-6(display_short)|uniprotkb:Abnormal chemotaxis protein 6(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin subunit A(gene name synonym)|uniprotkb:cna-1(gene name synonym)|uniprotkb:C02F4.2(orf name) psi-mi:kin29_caeel(display_long)|uniprotkb:kin-29(gene name)|psi-mi:kin-29(display_short)|uniprotkb:sma-11(gene name synonym)|uniprotkb:F58H12.1(orf name) psi-mi:"MI:0018"(two hybrid) Singaravelu et al. (2007) pubmed:17113567|imex:IM-19496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892314|imex:IM-19496-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021292.1|refseq:NP_001021293.2|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-CEL-2871809|reactome:R-CEL-4086398|reactome:R-CEL-5607763|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001076658.2|wormbase:C02F4.2a|wormbase:C02F4.2c|mint:Q0G819|ensemblmetazoa:C02F4.2b.1(transcript)|ensemblmetazoa:C02F4.2c.1(transcript)|ensemblmetazoa:WBGene00006527(gene)|ensemblmetazoa:WBGene00006527(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0010446"(response to alkaline pH)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0040024"(dauer larval development)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0097499"(protein localization to non-motile cilium)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|wormbase:C02F4.2b|dip:DIP-25135N|ensemblmetazoa:WBGene00006527(gene) ensemblmetazoa:F58H12.1.1(transcript)|ensemblmetazoa:WBGene00002210(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040024"(dauer larval development)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043053"(dauer entry)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_508493.1|wormbase:F58H12.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q21017 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/07/19 2016/07/12 rogid:fmiFwU/rnrr8VIbPAwRv1sqvTfs6239 rogid:4s8NpYym05Ph9ZIhp8KT4hY1h2U6239 intact-crc:8E4F98D063123E2F|rigid:YVtOh54rJY/u7PEWkDe8k10Ujbk false - sufficient binding region:326-822 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q0G819 uniprotkb:Q21017 intact:EBI-323063|intact:EBI-2412118|intact:EBI-7683011|intact:MINT-3383953|uniprotkb:Q86MD4|uniprotkb:Q95002|ensemblmetazoa:C02F4.2b.1|ensemblmetazoa:C02F4.2c.1 intact:EBI-2893174|ensemblmetazoa:F58H12.1.1 psi-mi:pp2b_caeel(display_long)|uniprotkb:tax-6(gene name)|psi-mi:tax-6(display_short)|uniprotkb:Abnormal chemotaxis protein 6(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin subunit A(gene name synonym)|uniprotkb:cna-1(gene name synonym)|uniprotkb:C02F4.2(orf name) psi-mi:kin29_caeel(display_long)|uniprotkb:kin-29(gene name)|psi-mi:kin-29(display_short)|uniprotkb:sma-11(gene name synonym)|uniprotkb:F58H12.1(orf name) psi-mi:"MI:0018"(two hybrid) Singaravelu et al. (2007) pubmed:17113567|imex:IM-19496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893187|imex:IM-19496-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021292.1|refseq:NP_001021293.2|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-CEL-2871809|reactome:R-CEL-4086398|reactome:R-CEL-5607763|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001076658.2|wormbase:C02F4.2a|wormbase:C02F4.2c|mint:Q0G819|ensemblmetazoa:C02F4.2b.1(transcript)|ensemblmetazoa:C02F4.2c.1(transcript)|ensemblmetazoa:WBGene00006527(gene)|ensemblmetazoa:WBGene00006527(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0010446"(response to alkaline pH)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0040024"(dauer larval development)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0097499"(protein localization to non-motile cilium)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|wormbase:C02F4.2b|dip:DIP-25135N|ensemblmetazoa:WBGene00006527(gene) ensemblmetazoa:F58H12.1.1(transcript)|ensemblmetazoa:WBGene00002210(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040024"(dauer larval development)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043053"(dauer entry)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_508493.1|wormbase:F58H12.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q21017 - - - figure legend:Fig 1A|caution:Exact coordinates of tax-6 constructs not given in the text.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/07/19 2016/07/12 rogid:fmiFwU/rnrr8VIbPAwRv1sqvTfs6239 rogid:4s8NpYym05Ph9ZIhp8KT4hY1h2U6239 intact-crc:F26AF940D7F24A4C|rigid:YVtOh54rJY/u7PEWkDe8k10Ujbk false necessary binding region:373..373-542 sufficient binding region:326-822 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q0G819 uniprotkb:Q21017 intact:EBI-323063|intact:EBI-2412118|intact:EBI-7683011|intact:MINT-3383953|uniprotkb:Q86MD4|uniprotkb:Q95002|ensemblmetazoa:C02F4.2b.1|ensemblmetazoa:C02F4.2c.1 intact:EBI-2893174|ensemblmetazoa:F58H12.1.1 psi-mi:pp2b_caeel(display_long)|uniprotkb:tax-6(gene name)|psi-mi:tax-6(display_short)|uniprotkb:Abnormal chemotaxis protein 6(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin subunit A(gene name synonym)|uniprotkb:cna-1(gene name synonym)|uniprotkb:C02F4.2(orf name) psi-mi:kin29_caeel(display_long)|uniprotkb:kin-29(gene name)|psi-mi:kin-29(display_short)|uniprotkb:sma-11(gene name synonym)|uniprotkb:F58H12.1(orf name) psi-mi:"MI:0096"(pull down) Singaravelu et al. (2007) pubmed:17113567|imex:IM-19496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893203|imex:IM-19496-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021292.1|refseq:NP_001021293.2|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-CEL-2871809|reactome:R-CEL-4086398|reactome:R-CEL-5607763|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001076658.2|wormbase:C02F4.2a|wormbase:C02F4.2c|mint:Q0G819|ensemblmetazoa:C02F4.2b.1(transcript)|ensemblmetazoa:C02F4.2c.1(transcript)|ensemblmetazoa:WBGene00006527(gene)|ensemblmetazoa:WBGene00006527(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0010446"(response to alkaline pH)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0040024"(dauer larval development)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0097499"(protein localization to non-motile cilium)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|wormbase:C02F4.2b|dip:DIP-25135N|ensemblmetazoa:WBGene00006527(gene) ensemblmetazoa:F58H12.1.1(transcript)|ensemblmetazoa:WBGene00002210(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040024"(dauer larval development)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043053"(dauer entry)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_508493.1|wormbase:F58H12.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q21017 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/19 2016/07/12 rogid:fmiFwU/rnrr8VIbPAwRv1sqvTfs6239 rogid:4s8NpYym05Ph9ZIhp8KT4hY1h2U6239 intact-crc:58F2AE89FCD319ED|rigid:YVtOh54rJY/u7PEWkDe8k10Ujbk false glutathione s tranferase tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)