#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32523 uniprotkb:Q06091 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-818|uniprotkb:D6W499|ensemblfungi:YPR101W psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:sn309_yeast(display_long)|uniprotkb:YPR101W(locus name)|uniprotkb:SNT309(gene name)|psi-mi:SNT309(display_short)|uniprotkb:NTC25(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 309(gene name synonym)|uniprotkb:PRP19-associated complex protein 25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 sgd:S000006305|refseq:NP_015426.1|dip:DIP-2864N|mint:Q06091|ensemblfungi:YPR101W(gene)|ensemblfungi:YPR101W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 crc64:B781CA65BC9A1918 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:ELyyYlQDmNRzWKQx/63xvHuAG8M559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:Q12309 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-484|uniprotkb:D6VYB5|ensemblfungi:YLR117C psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:clf1_yeast(display_long)|uniprotkb:CLF1(gene name)|psi-mi:CLF1(display_short)|uniprotkb:NTC77(gene name synonym)|uniprotkb:YLR117C(locus name)|uniprotkb:SYF3(gene name synonym)|uniprotkb:L2952(orf name)|uniprotkb:Crooked neck-like factor 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 77(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 refseq:NP_013218.1|sgd:S000004107|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|ensemblfungi:YLR117C(gene)|ensemblfungi:YLR117C_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-1685N|mint:Q12309 go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 crc64:AE7D5EC5B3979E00 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:VbNHO9YGUushIXHTgscFu4xCzC4559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:P21374 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-9382|ensemblfungi:YJR050W|uniprotkb:D6VWM1 psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:isy1_yeast(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:UTR3(gene name synonym)|uniprotkb:YJR050W(locus name)|uniprotkb:J1657(orf name)|uniprotkb:NTC30(gene name synonym)|uniprotkb:Interactor of SYF1(gene name synonym)|uniprotkb:PRP19-associated complex protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 ensemblfungi:YJR050W(gene)|ensemblfungi:YJR050W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|sgd:S000003811|refseq:NP_012584.3|mint:P21374|dip:DIP-1682N go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:NHLAtd+wLxwtWQD8PsyzyQsfJOg559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:P53277 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-23308|uniprotkb:D6VUR1|ensemblfungi:YGR129W psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:syf2_yeast(display_long)|uniprotkb:SYF2(gene name)|psi-mi:SYF2(display_short)|uniprotkb:NTC31(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 2(gene name synonym)|uniprotkb:PRP19 complex protein 31(gene name synonym)|uniprotkb:YGR129W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 sgd:S000003361|refseq:NP_011645.3|dip:DIP-1684N|mint:P53277|interpro:IPR013260(mRNA splicing factor SYF2)|ensemblfungi:YGR129W(gene)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|ensemblfungi:YGR129W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex) go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:uVAPXi98XAE2k7IPXvd4d+KNknw559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:Q04048 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-540|uniprotkb:D6VT47|ensemblfungi:YDR416W psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:syf1_yeast(display_long)|uniprotkb:SYF1(gene name)|psi-mi:SYF1(display_short)|uniprotkb:NTC90(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 90(gene name synonym)|uniprotkb:YDR416W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 refseq:NP_010704.1|sgd:S000002824|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|rcsb pdb:5Y88|ensemblfungi:YDR416W(gene)|ensemblfungi:YDR416W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|dip:DIP-1681N|mint:Q04048 go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 crc64:ED4368A624A40E7C figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:+1TwiqsQv1IcWxuoIWcJGtTCUFU559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:P38302 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 crc64:15C5234B25213223 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32523 uniprotkb:Q03654 intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038 psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924708|imex:IM-20514-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654 go:"GO:0000974"(Prp19 complex) crc64:A44D8C7DD6F64185 crc64:A4C417A8B330EA9C figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292 intact-crc:6650C6D5656A7F13|rigid:Ppl/kSMXOo3Re9UuecgCGL4Q1Jg false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P53277 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-23308|uniprotkb:D6VUR1|ensemblfungi:YGR129W psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:syf2_yeast(display_long)|uniprotkb:SYF2(gene name)|psi-mi:SYF2(display_short)|uniprotkb:NTC31(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 2(gene name synonym)|uniprotkb:PRP19 complex protein 31(gene name synonym)|uniprotkb:YGR129W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 sgd:S000003361|refseq:NP_011645.3|dip:DIP-1684N|mint:P53277|interpro:IPR013260(mRNA splicing factor SYF2)|ensemblfungi:YGR129W(gene)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|ensemblfungi:YGR129W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex) - crc64:9986B547B9582338 - figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:uVAPXi98XAE2k7IPXvd4d+KNknw559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:Q12309 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-484|uniprotkb:D6VYB5|ensemblfungi:YLR117C psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:clf1_yeast(display_long)|uniprotkb:CLF1(gene name)|psi-mi:CLF1(display_short)|uniprotkb:NTC77(gene name synonym)|uniprotkb:YLR117C(locus name)|uniprotkb:SYF3(gene name synonym)|uniprotkb:L2952(orf name)|uniprotkb:Crooked neck-like factor 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 77(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_013218.1|sgd:S000004107|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|ensemblfungi:YLR117C(gene)|ensemblfungi:YLR117C_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-1685N|mint:Q12309 - crc64:9986B547B9582338 crc64:AE7D5EC5B3979E00 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:VbNHO9YGUushIXHTgscFu4xCzC4559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:Q06091 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-818|uniprotkb:D6W499|ensemblfungi:YPR101W psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:sn309_yeast(display_long)|uniprotkb:YPR101W(locus name)|uniprotkb:SNT309(gene name)|psi-mi:SNT309(display_short)|uniprotkb:NTC25(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 309(gene name synonym)|uniprotkb:PRP19-associated complex protein 25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 sgd:S000006305|refseq:NP_015426.1|dip:DIP-2864N|mint:Q06091|ensemblfungi:YPR101W(gene)|ensemblfungi:YPR101W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q - crc64:9986B547B9582338 crc64:B781CA65BC9A1918 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:ELyyYlQDmNRzWKQx/63xvHuAG8M559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P21374 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-9382|ensemblfungi:YJR050W|uniprotkb:D6VWM1 psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:isy1_yeast(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:UTR3(gene name synonym)|uniprotkb:YJR050W(locus name)|uniprotkb:J1657(orf name)|uniprotkb:NTC30(gene name synonym)|uniprotkb:Interactor of SYF1(gene name synonym)|uniprotkb:PRP19-associated complex protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 ensemblfungi:YJR050W(gene)|ensemblfungi:YJR050W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|sgd:S000003811|refseq:NP_012584.3|mint:P21374|dip:DIP-1682N - crc64:9986B547B9582338 - figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:NHLAtd+wLxwtWQD8PsyzyQsfJOg559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:Q04048 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-540|uniprotkb:D6VT47|ensemblfungi:YDR416W psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:syf1_yeast(display_long)|uniprotkb:SYF1(gene name)|psi-mi:SYF1(display_short)|uniprotkb:NTC90(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 90(gene name synonym)|uniprotkb:YDR416W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_010704.1|sgd:S000002824|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|rcsb pdb:5Y88|ensemblfungi:YDR416W(gene)|ensemblfungi:YDR416W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|dip:DIP-1681N|mint:Q04048 - crc64:9986B547B9582338 crc64:ED4368A624A40E7C figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:+1TwiqsQv1IcWxuoIWcJGtTCUFU559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P38302 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N - crc64:9986B547B9582338 crc64:15C5234B25213223 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P32523 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 - crc64:9986B547B9582338 crc64:A44D8C7DD6F64185 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:Q03654 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038 psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924730|imex:IM-20514-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654 - crc64:9986B547B9582338 crc64:A4C417A8B330EA9C figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with SPP3982, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292 intact-crc:88CE50B473798CC5|rigid:UWtygkNtiiuamhyFIbvbQOH30OI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q04048 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-540|uniprotkb:D6VT47|ensemblfungi:YDR416W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:syf1_yeast(display_long)|uniprotkb:SYF1(gene name)|psi-mi:SYF1(display_short)|uniprotkb:NTC90(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 90(gene name synonym)|uniprotkb:YDR416W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_010704.1|sgd:S000002824|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|rcsb pdb:5Y88|ensemblfungi:YDR416W(gene)|ensemblfungi:YDR416W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|dip:DIP-1681N|mint:Q04048 - - crc64:ED4368A624A40E7C figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:+1TwiqsQv1IcWxuoIWcJGtTCUFU559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P21374 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-9382|ensemblfungi:YJR050W|uniprotkb:D6VWM1 psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:isy1_yeast(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:UTR3(gene name synonym)|uniprotkb:YJR050W(locus name)|uniprotkb:J1657(orf name)|uniprotkb:NTC30(gene name synonym)|uniprotkb:Interactor of SYF1(gene name synonym)|uniprotkb:PRP19-associated complex protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 ensemblfungi:YJR050W(gene)|ensemblfungi:YJR050W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|sgd:S000003811|refseq:NP_012584.3|mint:P21374|dip:DIP-1682N - - - figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:NHLAtd+wLxwtWQD8PsyzyQsfJOg559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P53277 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-23308|uniprotkb:D6VUR1|ensemblfungi:YGR129W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:syf2_yeast(display_long)|uniprotkb:SYF2(gene name)|psi-mi:SYF2(display_short)|uniprotkb:NTC31(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 2(gene name synonym)|uniprotkb:PRP19 complex protein 31(gene name synonym)|uniprotkb:YGR129W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 sgd:S000003361|refseq:NP_011645.3|dip:DIP-1684N|mint:P53277|interpro:IPR013260(mRNA splicing factor SYF2)|ensemblfungi:YGR129W(gene)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|ensemblfungi:YGR129W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex) - - - figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:uVAPXi98XAE2k7IPXvd4d+KNknw559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q12309 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-484|uniprotkb:D6VYB5|ensemblfungi:YLR117C psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:clf1_yeast(display_long)|uniprotkb:CLF1(gene name)|psi-mi:CLF1(display_short)|uniprotkb:NTC77(gene name synonym)|uniprotkb:YLR117C(locus name)|uniprotkb:SYF3(gene name synonym)|uniprotkb:L2952(orf name)|uniprotkb:Crooked neck-like factor 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 77(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013218.1|sgd:S000004107|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|ensemblfungi:YLR117C(gene)|ensemblfungi:YLR117C_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-1685N|mint:Q12309 - - crc64:AE7D5EC5B3979E00 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:VbNHO9YGUushIXHTgscFu4xCzC4559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q06091 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-818|uniprotkb:D6W499|ensemblfungi:YPR101W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:sn309_yeast(display_long)|uniprotkb:YPR101W(locus name)|uniprotkb:SNT309(gene name)|psi-mi:SNT309(display_short)|uniprotkb:NTC25(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 309(gene name synonym)|uniprotkb:PRP19-associated complex protein 25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 sgd:S000006305|refseq:NP_015426.1|dip:DIP-2864N|mint:Q06091|ensemblfungi:YPR101W(gene)|ensemblfungi:YPR101W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q - - crc64:B781CA65BC9A1918 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:ELyyYlQDmNRzWKQx/63xvHuAG8M559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P32523 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9 psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523 - - crc64:A44D8C7DD6F64185 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q03654 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038 psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654 - - crc64:A4C417A8B330EA9C figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P38302 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924745|imex:IM-20514-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N - - crc64:15C5234B25213223 figure legend:Fig. 1A|comment:All the identified PRP19 complex components were coprecipitated with NTR2, but at much lower levels than those coprecipitated with Prp19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292 intact-crc:51B003E74D18DB18|rigid:k/fFMXSaN8oW+SKb24B6rKTomHQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53131 uniprotkb:P36118 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924759|imex:IM-20514-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 - comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 intact-crc:87198F5A60C28BE6|rigid:9274BISWq3rUWu11kVaCg7COyAo false v5 tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53131 uniprotkb:Q06411 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924759|imex:IM-20514-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 crc64:9986B547B9582338 comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:87198F5A60C28BE6|rigid:9274BISWq3rUWu11kVaCg7COyAo false v5 tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P53131 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924772|imex:IM-20514-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 - crc64:9986B547B9582338 crc64:DA8A085EC50FF430 comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:09E0E00644805132|rigid:9274BISWq3rUWu11kVaCg7COyAo false ha tag:?-? v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06411 uniprotkb:P36118 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924772|imex:IM-20514-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 - crc64:9986B547B9582338 - comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 intact-crc:09E0E00644805132|rigid:9274BISWq3rUWu11kVaCg7COyAo false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53131 uniprotkb:P36118 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924784|imex:IM-20514-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 - comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 intact-crc:8C6BFCC6E9F594AD|rigid:9274BISWq3rUWu11kVaCg7COyAo false v5 tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53131 uniprotkb:Q06411 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2924784|imex:IM-20514-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 crc64:9986B547B9582338 comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:8C6BFCC6E9F594AD|rigid:9274BISWq3rUWu11kVaCg7COyAo false v5 tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q06411 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925062|imex:IM-20514-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - - crc64:9986B547B9582338 comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:850A557179968A05|rigid:9274BISWq3rUWu11kVaCg7COyAo false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P53131 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925062|imex:IM-20514-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 - - crc64:DA8A085EC50FF430 comment:Trace amounts of PRP19 were also observed in the complex|figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:850A557179968A05|rigid:9274BISWq3rUWu11kVaCg7COyAo false ha tag:?-? v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:P53131 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0029"(cosedimentation through density gradient) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925080|imex:IM-20514-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 - - crc64:DA8A085EC50FF430 figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:341452C54DD34011|rigid:9274BISWq3rUWu11kVaCg7COyAo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q06411 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925080|imex:IM-20514-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - - crc64:9986B547B9582338 figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:341452C54DD34011|rigid:9274BISWq3rUWu11kVaCg7COyAo false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36118 uniprotkb:Q06411 intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925095|imex:IM-20514-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - - crc64:9986B547B9582338 figure legend:Fig. 6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:9AC1E243F17A5FEC|rigid:gr9TJ9mtdd97/zEOHjpDc4qLisw false - necessary binding region:123-344 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:Q06411 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925101|imex:IM-20514-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 crc64:9986B547B9582338 figure legend:Fig. 6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:9DE9D20EE28249D1|rigid:p5CPWAcSC+uFDl5YTyxUShGWsRs false - necessary binding region:63-109(IPR000467) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06411 uniprotkb:Q06411 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925108|imex:IM-20514-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - crc64:9986B547B9582338 crc64:9986B547B9582338 figure legend:Fig. 6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:3F0E256486EF9E32|rigid:2nM2mhw3OSRROKvPIEzQK0P5ulo false necessary binding region:264-581 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:Q06411 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsai et al. (2005) pubmed:16357217|imex:IM-20514 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2925115|imex:IM-20514-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 - crc64:DA8A085EC50FF430 crc64:9986B547B9582338 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/09/10 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:D2003D0D43685EF3|rigid:p5CPWAcSC+uFDl5YTyxUShGWsRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)