#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y3D8	uniprotkb:P38432	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Santama et al. (2005)	pubmed:16079131|imex:IM-20491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2892200|imex:IM-20491-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	-	-	figure legend:Fig 1A, Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/07/19	2014/10/16	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:8BA204252971D5AE|rigid:URDWD3TRP3iPfBiDY10ehqRx0Q8	false	-	sufficient binding region:362-576	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38432	uniprotkb:Q9Y3D8	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Santama et al. (2005)	pubmed:16079131|imex:IM-20491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2892257|imex:IM-20491-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	go:"GO:0015030"(Cajal body)	-	-	comment:The nuclear bodies containing hCINAP co-localized with anti-coilin antibodies, indicating that the structures are Cajal bodies.  Nuclei transfected with YFP-hCINAP  have a reduced number of Cajal bodies per nucleus.|figure legend:Fig 5,  Fig 8.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/07/19	2014/10/16	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	intact-crc:1968AE001F1E3262|rigid:URDWD3TRP3iPfBiDY10ehqRx0Q8	false	-	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9Y3D8	uniprotkb:P38432	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Santama et al. (2005)	pubmed:16079131|imex:IM-20491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2892294|imex:IM-20491-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	-	-	figure legend:Fig 6B.|comment:Coilin is detectable on the glutathione beads only in the presence of hCINAP and the hCINAP-coilin interaction appears to be ATP-independent.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/19	2014/10/16	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:75C755D487EE3A45|rigid:URDWD3TRP3iPfBiDY10ehqRx0Q8	false	glutathione s tranferase tag:?-?	his tag:?-?|tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3D8	uniprotkb:P38432	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Santama et al. (2005)	pubmed:16079131|imex:IM-20491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2892321|imex:IM-20491-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	-	-	figure legend:Fig 6C.|comment:Binding of endogenous coilin to YFP-tagged hCINAP in transiently transfected HeLa cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/07/19	2014/10/16	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:FF8BF9C2B00A7DD1|rigid:URDWD3TRP3iPfBiDY10ehqRx0Q8	false	yellow fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38432	uniprotkb:Q9Y3D8	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:"MI:0096"(pull down)	Santama et al. (2005)	pubmed:16079131|imex:IM-20491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2892380|imex:IM-20491-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	-	-	-	comment:An essential CINAP interaction domain lies within the carboxyl-terminal 214 amino acid residues of coilin.|figure legend:Fig 7B.|comment:The C1 fragment is recovered in the pellet of the glutathione agarose pull-down only in the presence of GST-CINAP and is absent from the pellet when GST-CINAP is not expressed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/19	2014/10/16	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	intact-crc:EAFC0F1026ED5E62|rigid:URDWD3TRP3iPfBiDY10ehqRx0Q8	false	sufficient binding region:362-576|35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)