#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8NHL6	uniprotkb:P41240	intact:EBI-2805262|uniprotkb:Q8NHK0|uniprotkb:Q8NHJ9|uniprotkb:O75025|uniprotkb:O75024|uniprotkb:A8MXT0|ensembl:ENSP00000480365|ensembl:ENSP00000481700|uniprotkb:A2IXV4	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906	psi-mi:lirb1_human(display_long)|uniprotkb:ILT2(gene name synonym)|uniprotkb:LIR1(gene name synonym)|uniprotkb:MIR7(gene name synonym)|uniprotkb:CD85 antigen-like family member J(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 2(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 7(gene name synonym)|uniprotkb:LILRB1(gene name)|psi-mi:LILRB1(display_short)	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Sayós et al. (2004)	pubmed:15474475|mint:MINT-6731652	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7351403|mint:MINT-8027327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000274669(gene)|ensembl:ENSG00000277807(gene)|ensembl:ENST00000616408(transcript)|ensembl:ENST00000618055(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014063"(negative regulation of serotonin secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030107"(HLA-A specific inhibitory MHC class I receptor activity)|go:"GO:0030109"(HLA-B specific inhibitory MHC class I receptor activity)|go:"GO:0031623"(receptor internalization)|go:"GO:0032393"(MHC class I receptor activity)|go:"GO:0032394"(MHC class Ib receptor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001193"(positive regulation of gamma-delta T cell activation involved in immune response)|go:"GO:2001199"(negative regulation of dendritic cell differentiation)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q8NHL6|rcsb pdb:1G0X|rcsb pdb:1P7Q|rcsb pdb:1UFU|rcsb pdb:1UGN|rcsb pdb:1VDG|rcsb pdb:3D2U|rcsb pdb:4LL9|rcsb pdb:4NO0|rcsb pdb:5KNM|rcsb pdb:6AEE|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6K60|rcsb pdb:6ZDX|rcsb pdb:7KFK|reactome:R-HSA-198933|go:"GO:0097028"(dendritic cell differentiation)|refseq:NP_001265328.2|refseq:NP_001075106.2|refseq:NP_001075107.2|refseq:NP_001075108.2|refseq:NP_001265327.2|refseq:NP_006660.4|mint:MINT-8027331(identity)|uniprotkb:Q8NHL6(original identifier)	refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|mint:MINT-8027328(identity)|uniprotkb:P41240(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:c3bdpF4SePNjbOkhewak+Vj98hU9606	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	intact-crc:C1E42405E3F94635|rigid:HOI8aWJKkJa1tMDwB2MkKBz8uRI	false	phosphorylated residue:562-562(MINT-8027336)|binding-associated region:555-568(MINT-8027334)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41240	uniprotkb:Q8NHL6	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906	intact:EBI-2805262|uniprotkb:Q8NHK0|uniprotkb:Q8NHJ9|uniprotkb:O75025|uniprotkb:O75024|uniprotkb:A8MXT0|ensembl:ENSP00000480365|ensembl:ENSP00000481700|uniprotkb:A2IXV4	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:lirb1_human(display_long)|uniprotkb:ILT2(gene name synonym)|uniprotkb:LIR1(gene name synonym)|uniprotkb:MIR7(gene name synonym)|uniprotkb:CD85 antigen-like family member J(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 2(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 7(gene name synonym)|uniprotkb:LILRB1(gene name)|psi-mi:LILRB1(display_short)	psi-mi:"MI:0437"(protein three hybrid)	Sayós et al. (2004)	pubmed:15474475|mint:MINT-6731652	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7351451|mint:MINT-8027342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|mint:MINT-8027343(identity)|uniprotkb:P41240(original identifier)	ensembl:ENSG00000274669(gene)|ensembl:ENSG00000277807(gene)|ensembl:ENST00000616408(transcript)|ensembl:ENST00000618055(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014063"(negative regulation of serotonin secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030107"(HLA-A specific inhibitory MHC class I receptor activity)|go:"GO:0030109"(HLA-B specific inhibitory MHC class I receptor activity)|go:"GO:0031623"(receptor internalization)|go:"GO:0032393"(MHC class I receptor activity)|go:"GO:0032394"(MHC class Ib receptor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001193"(positive regulation of gamma-delta T cell activation involved in immune response)|go:"GO:2001199"(negative regulation of dendritic cell differentiation)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q8NHL6|rcsb pdb:1G0X|rcsb pdb:1P7Q|rcsb pdb:1UFU|rcsb pdb:1UGN|rcsb pdb:1VDG|rcsb pdb:3D2U|rcsb pdb:4LL9|rcsb pdb:4NO0|rcsb pdb:5KNM|rcsb pdb:6AEE|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6K60|rcsb pdb:6ZDX|rcsb pdb:7KFK|reactome:R-HSA-198933|go:"GO:0097028"(dendritic cell differentiation)|refseq:NP_001265328.2|refseq:NP_001075106.2|refseq:NP_001075107.2|refseq:NP_001075108.2|refseq:NP_001265327.2|refseq:NP_006660.4|mint:MINT-8027346(identity)|uniprotkb:Q8NHL6(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:c3bdpF4SePNjbOkhewak+Vj98hU9606	intact-crc:08D1CDE1AB64575A|rigid:HOI8aWJKkJa1tMDwB2MkKBz8uRI	false	-	binding-associated region:555-568(MINT-8027349)|phosphorylated residue:562-562(MINT-8027351)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)