#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43404	uniprotkb:Q8R4V1	intact:EBI-3862932|uniprotkb:P97455|uniprotkb:Q80VV2|uniprotkb:Q8CHJ3|ensembl:ENSMUSP00000027291	intact:EBI-7187310|ensembl:ENSMUSP00000154945|intact:MINT-8019956|uniprotkb:Q9D5Z3|uniprotkb:Q3UAX8	psi-mi:zap70_mouse(display_long)|uniprotkb:Zap70(gene name)|psi-mi:Zap70(display_short)|uniprotkb:Srk(gene name synonym)|uniprotkb:Zap-70(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:nfam1_mouse(display_long)|uniprotkb:Nfam1(gene name)|psi-mi:Nfam1(display_short)|uniprotkb:Cnaip(gene name synonym)|uniprotkb:NFAT-activating protein with ITAM motif 1(gene name synonym)|uniprotkb:Calcineurin/NFAT-activating ITAM-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ohtsuka et al. (2004)	pubmed:15143214|mint:MINT-6731635	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187341|mint:MINT-8030535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033565.2|refseq:NP_001276541.1|refseq:NP_001276694.1|refseq:XP_006495959.1|ensembl:ENSMUSG00000026117(gene)|ensembl:ENSMUST00000027291(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-9013407|go:"GO:0005737"(cytoplasm)|mint:MINT-8030536(identity)|uniprotkb:P43404(original identifier)	ensembl:ENSMUSG00000058099(gene)|ensembl:ENSMUST00000231165(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR033549|reactome:R-MMU-6798695|go:"GO:0005886"(plasma membrane)|refseq:NP_001258341.1|refseq:NP_001258340.1|refseq:NP_001258343.1|refseq:NP_001258342.1|refseq:NP_083004.1|mint:MINT-8030539(identity)|uniprotkb:Q8R4V1(original identifier)	-	-	comment:mint	comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:/6vag4l7UgKTQxiRJVx2KU23r1410090	rogid:SXKyD3UGYWeahbVK/1YMOEhLx/010090	intact-crc:1D55D0ED09D22397|rigid:ACLks9x4SrM02J5YNzL8LDaYoiQ	false	-	phosphorylated residue:215-215(MINT-8030544)|binding-associated region:208-221(MINT-8030542)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8R4V1	uniprotkb:P43405	intact:EBI-7187310|ensembl:ENSMUSP00000154945|intact:MINT-8019956|uniprotkb:Q9D5Z3|uniprotkb:Q3UAX8	intact:EBI-78302|ensembl:ENSP00000364898|ensembl:ENSP00000364907	psi-mi:nfam1_mouse(display_long)|uniprotkb:Nfam1(gene name)|psi-mi:Nfam1(display_short)|uniprotkb:Cnaip(gene name synonym)|uniprotkb:NFAT-activating protein with ITAM motif 1(gene name synonym)|uniprotkb:Calcineurin/NFAT-activating ITAM-containing protein(gene name synonym)	psi-mi:ksyk_human(display_long)|uniprotkb:SYK(gene name)|psi-mi:SYK(display_short)|uniprotkb:Spleen tyrosine kinase(gene name synonym)|uniprotkb:p72-Syk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ohtsuka et al. (2004)	pubmed:15143214|mint:MINT-6731635	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187358|mint:MINT-8030546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058099(gene)|ensembl:ENSMUST00000231165(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR033549|reactome:R-MMU-6798695|go:"GO:0005886"(plasma membrane)|refseq:NP_001258341.1|refseq:NP_001258340.1|refseq:NP_001258343.1|refseq:NP_001258342.1|refseq:NP_083004.1|mint:MINT-8030550(identity)|uniprotkb:Q8R4V1(original identifier)	refseq:NP_001128524.1|refseq:NP_001167638.1|refseq:NP_001167639.1|refseq:NP_003168.2|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043313"(regulation of neutrophil degranulation)|go:"GO:0043366"(beta selection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071226"(cellular response to molecule of fungal origin)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090237"(regulation of arachidonic acid secretion)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990858"(cellular response to lectin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43405|rcsb pdb:1A81|rcsb pdb:1CSY|rcsb pdb:1CSZ|rcsb pdb:1XBA|rcsb pdb:1XBB|rcsb pdb:1XBC|rcsb pdb:3BUW|rcsb pdb:3EMG|rcsb pdb:3FQE|rcsb pdb:3FQH|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019815"(B cell receptor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032009"(early phagosome)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032752"(positive regulation of interleukin-3 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032928"(regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0016170"(interleukin-15 receptor binding)|rcsb pdb:3FQS|rcsb pdb:3SRV|rcsb pdb:3TUB|rcsb pdb:3TUC|rcsb pdb:3TUD|rcsb pdb:3VF8|rcsb pdb:3VF9|rcsb pdb:4DFL|rcsb pdb:4DFN|rcsb pdb:4F4P|rcsb pdb:4FL1|rcsb pdb:4FL2|rcsb pdb:4FL3|rcsb pdb:4FYN|rcsb pdb:4FYO|rcsb pdb:4FZ6|rcsb pdb:4FZ7|rcsb pdb:4GFG|rcsb pdb:4I0R|ensembl:ENSG00000165025(gene)|ensembl:ENST00000375746(transcript)|ensembl:ENST00000375754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|rcsb pdb:4I0S|rcsb pdb:4I0T|rcsb pdb:4PUZ|rcsb pdb:4PV0|rcsb pdb:4PX6|rcsb pdb:4RSS|rcsb pdb:4RX7|rcsb pdb:4RX8|rcsb pdb:4RX9|rcsb pdb:4WNM|rcsb pdb:4XG2|rcsb pdb:4XG3|rcsb pdb:5TIU|rcsb pdb:5TR6|rcsb pdb:5TT7|rcsb pdb:5Y5T|rcsb pdb:5Y5U|rcsb pdb:6HM6|rcsb pdb:6HM7|rcsb pdb:6SSB|rcsb pdb:6VOV|rcsb pdb:6ZC0|rcsb pdb:6ZCP|rcsb pdb:6ZCQ|rcsb pdb:6ZCR|rcsb pdb:6ZCS|rcsb pdb:6ZCU|rcsb pdb:6ZCX|rcsb pdb:6ZCY|rcsb pdb:4XG4|reactome:R-HSA-114604|reactome:R-HSA-2029481|reactome:R-HSA-2029482|rcsb pdb:4XG7|rcsb pdb:4XG8|rcsb pdb:4XG9|rcsb pdb:4YJO|rcsb pdb:4YJP|rcsb pdb:4YJQ|rcsb pdb:4YJR|rcsb pdb:4YJS|rcsb pdb:4YJT|rcsb pdb:4YJU|rcsb pdb:4YJV|rcsb pdb:5C26|rcsb pdb:5C27|rcsb pdb:5CXH|rcsb pdb:5CXZ|rcsb pdb:5CY3|rcsb pdb:5GHV|rcsb pdb:5LMA|rcsb pdb:4XG6|rcsb pdb:5LMB|rcsb pdb:5T68|refseq:XP_011517248.1|refseq:XP_005252204.1|reactome:R-HSA-2029485|reactome:R-HSA-2424491|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-5607764|reactome:R-HSA-5621480|reactome:R-HSA-9020558|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|reactome:R-HSA-983695|dip:DIP-253N|mint:MINT-8030547(identity)|uniprotkb:P43405(original identifier)	-	comment:mint	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:SXKyD3UGYWeahbVK/1YMOEhLx/010090	rogid:SAOtCMFKG07Wej573EklHjusYVA9606	intact-crc:9B33C28C6A04995B|rigid:4skdqBgwZ2WKVevqN0q1PHjE1f8	false	binding-associated region:208-221(MINT-8030553)|phosphorylated residue:215-215(MINT-8030555)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8R4V1	uniprotkb:P43405	intact:EBI-7187310|ensembl:ENSMUSP00000154945|intact:MINT-8019956|uniprotkb:Q9D5Z3|uniprotkb:Q3UAX8	intact:EBI-78302|ensembl:ENSP00000364898|ensembl:ENSP00000364907	psi-mi:nfam1_mouse(display_long)|uniprotkb:Nfam1(gene name)|psi-mi:Nfam1(display_short)|uniprotkb:Cnaip(gene name synonym)|uniprotkb:NFAT-activating protein with ITAM motif 1(gene name synonym)|uniprotkb:Calcineurin/NFAT-activating ITAM-containing protein(gene name synonym)	psi-mi:ksyk_human(display_long)|uniprotkb:SYK(gene name)|psi-mi:SYK(display_short)|uniprotkb:Spleen tyrosine kinase(gene name synonym)|uniprotkb:p72-Syk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ohtsuka et al. (2004)	pubmed:15143214|mint:MINT-6731635	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187409|mint:MINT-8036881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058099(gene)|ensembl:ENSMUST00000231165(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR033549|reactome:R-MMU-6798695|go:"GO:0005886"(plasma membrane)|refseq:NP_001258341.1|refseq:NP_001258340.1|refseq:NP_001258343.1|refseq:NP_001258342.1|refseq:NP_083004.1|mint:MINT-8036885(identity)|uniprotkb:Q8R4V1(original identifier)	refseq:NP_001128524.1|refseq:NP_001167638.1|refseq:NP_001167639.1|refseq:NP_003168.2|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043313"(regulation of neutrophil degranulation)|go:"GO:0043366"(beta selection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071226"(cellular response to molecule of fungal origin)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090237"(regulation of arachidonic acid secretion)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990858"(cellular response to lectin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43405|rcsb pdb:1A81|rcsb pdb:1CSY|rcsb pdb:1CSZ|rcsb pdb:1XBA|rcsb pdb:1XBB|rcsb pdb:1XBC|rcsb pdb:3BUW|rcsb pdb:3EMG|rcsb pdb:3FQE|rcsb pdb:3FQH|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019815"(B cell receptor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032009"(early phagosome)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032752"(positive regulation of interleukin-3 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032928"(regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0016170"(interleukin-15 receptor binding)|rcsb pdb:3FQS|rcsb pdb:3SRV|rcsb pdb:3TUB|rcsb pdb:3TUC|rcsb pdb:3TUD|rcsb pdb:3VF8|rcsb pdb:3VF9|rcsb pdb:4DFL|rcsb pdb:4DFN|rcsb pdb:4F4P|rcsb pdb:4FL1|rcsb pdb:4FL2|rcsb pdb:4FL3|rcsb pdb:4FYN|rcsb pdb:4FYO|rcsb pdb:4FZ6|rcsb pdb:4FZ7|rcsb pdb:4GFG|rcsb pdb:4I0R|ensembl:ENSG00000165025(gene)|ensembl:ENST00000375746(transcript)|ensembl:ENST00000375754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|rcsb pdb:4I0S|rcsb pdb:4I0T|rcsb pdb:4PUZ|rcsb pdb:4PV0|rcsb pdb:4PX6|rcsb pdb:4RSS|rcsb pdb:4RX7|rcsb pdb:4RX8|rcsb pdb:4RX9|rcsb pdb:4WNM|rcsb pdb:4XG2|rcsb pdb:4XG3|rcsb pdb:5TIU|rcsb pdb:5TR6|rcsb pdb:5TT7|rcsb pdb:5Y5T|rcsb pdb:5Y5U|rcsb pdb:6HM6|rcsb pdb:6HM7|rcsb pdb:6SSB|rcsb pdb:6VOV|rcsb pdb:6ZC0|rcsb pdb:6ZCP|rcsb pdb:6ZCQ|rcsb pdb:6ZCR|rcsb pdb:6ZCS|rcsb pdb:6ZCU|rcsb pdb:6ZCX|rcsb pdb:6ZCY|rcsb pdb:4XG4|reactome:R-HSA-114604|reactome:R-HSA-2029481|reactome:R-HSA-2029482|rcsb pdb:4XG7|rcsb pdb:4XG8|rcsb pdb:4XG9|rcsb pdb:4YJO|rcsb pdb:4YJP|rcsb pdb:4YJQ|rcsb pdb:4YJR|rcsb pdb:4YJS|rcsb pdb:4YJT|rcsb pdb:4YJU|rcsb pdb:4YJV|rcsb pdb:5C26|rcsb pdb:5C27|rcsb pdb:5CXH|rcsb pdb:5CXZ|rcsb pdb:5CY3|rcsb pdb:5GHV|rcsb pdb:5LMA|rcsb pdb:4XG6|rcsb pdb:5LMB|rcsb pdb:5T68|refseq:XP_011517248.1|refseq:XP_005252204.1|reactome:R-HSA-2029485|reactome:R-HSA-2424491|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-5607764|reactome:R-HSA-5621480|reactome:R-HSA-9020558|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|reactome:R-HSA-983695|dip:DIP-253N|mint:MINT-8036882(identity)|uniprotkb:P43405(original identifier)	-	comment:mint	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:SXKyD3UGYWeahbVK/1YMOEhLx/010090	rogid:SAOtCMFKG07Wej573EklHjusYVA9606	intact-crc:50F99C7E47CFC8A7|rigid:4skdqBgwZ2WKVevqN0q1PHjE1f8	false	phosphorylated residue:226-226(MINT-8036890)|binding-associated region:219-232(MINT-8036888)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43404	uniprotkb:Q8R4V1	intact:EBI-3862932|uniprotkb:P97455|uniprotkb:Q80VV2|uniprotkb:Q8CHJ3|ensembl:ENSMUSP00000027291	intact:EBI-7187310|ensembl:ENSMUSP00000154945|intact:MINT-8019956|uniprotkb:Q9D5Z3|uniprotkb:Q3UAX8	psi-mi:zap70_mouse(display_long)|uniprotkb:Zap70(gene name)|psi-mi:Zap70(display_short)|uniprotkb:Srk(gene name synonym)|uniprotkb:Zap-70(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:nfam1_mouse(display_long)|uniprotkb:Nfam1(gene name)|psi-mi:Nfam1(display_short)|uniprotkb:Cnaip(gene name synonym)|uniprotkb:NFAT-activating protein with ITAM motif 1(gene name synonym)|uniprotkb:Calcineurin/NFAT-activating ITAM-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ohtsuka et al. (2004)	pubmed:15143214|mint:MINT-6731635	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187392|mint:MINT-8036870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033565.2|refseq:NP_001276541.1|refseq:NP_001276694.1|refseq:XP_006495959.1|ensembl:ENSMUSG00000026117(gene)|ensembl:ENSMUST00000027291(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-9013407|go:"GO:0005737"(cytoplasm)|mint:MINT-8036871(identity)|uniprotkb:P43404(original identifier)	ensembl:ENSMUSG00000058099(gene)|ensembl:ENSMUST00000231165(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR033549|reactome:R-MMU-6798695|go:"GO:0005886"(plasma membrane)|refseq:NP_001258341.1|refseq:NP_001258340.1|refseq:NP_001258343.1|refseq:NP_001258342.1|refseq:NP_083004.1|mint:MINT-8036874(identity)|uniprotkb:Q8R4V1(original identifier)	-	-	comment:mint	comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:/6vag4l7UgKTQxiRJVx2KU23r1410090	rogid:SXKyD3UGYWeahbVK/1YMOEhLx/010090	intact-crc:A04C3751932CFFB0|rigid:ACLks9x4SrM02J5YNzL8LDaYoiQ	false	-	binding-associated region:219-232(MINT-8036877)|phosphorylated residue:226-226(MINT-8036879)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)