#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O55033 uniprotkb:P52800 intact:EBI-2642725|ensembl:ENSMUSP00000083611 intact:EBI-1032676|ensembl:ENSMUSP00000001319 psi-mi:nck2_mouse(display_long)|uniprotkb:Nck2(gene name)|psi-mi:Nck2(display_short)|uniprotkb:Grb4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym) psi-mi:efnb2_mouse(display_long)|uniprotkb:Elf2(gene name synonym)|uniprotkb:Epl5(gene name synonym)|uniprotkb:Eplg5(gene name synonym)|uniprotkb:Htkl(gene name synonym)|uniprotkb:Lerk5(gene name synonym)|uniprotkb:Efnb2(gene name)|psi-mi:Efnb2(display_short)|uniprotkb:EPH-related receptor tyrosine kinase ligand 5(gene name synonym)|uniprotkb:ELF-2(gene name synonym)|uniprotkb:HTK ligand(gene name synonym) psi-mi:"MI:0096"(pull down) Su et al. (2004) pubmed:15096211|mint:MINT-6731623|doi:10.1111/j.1432-1033.2004.04078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7169093|mint:MINT-8038311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035009.3|ensembl:ENSMUSG00000066877(gene)|ensembl:ENSMUST00000086421(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O55033|reactome:R-MMU-186763|reactome:R-MMU-373753|reactome:R-MMU-3928664|reactome:R-MMU-4420097|reactome:R-MMU-9013420|reactome:R-MMU-9013424|mint:MINT-8038312(identity)|uniprotkb:O55033(original identifier) refseq:NP_034241.2|ensembl:ENSMUSG00000001300(gene)|ensembl:ENSMUST00000001319(transcript)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52800|rcsb pdb:1IKO|rcsb pdb:1KGY|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|dip:DIP-29208N|mint:MINT-8038315(identity)|uniprotkb:P52800(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/29 2014/10/16 rogid:mFoknzNaD3XbNFCp57d5BUqEtAo10090 rogid:P051BaTxVceRTs9h3ugIgtq/EGo10090 intact-crc:15C4E14741D59889|rigid:YXj8rCg5TvdrkGcQcqeuNGN3VLs false - binding-associated region:300-313(MINT-8038318)|phosphorylated residue:307-307(MINT-8038320) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52800 uniprotkb:O55033 intact:EBI-1032676|ensembl:ENSMUSP00000001319 intact:EBI-2642725|ensembl:ENSMUSP00000083611 psi-mi:efnb2_mouse(display_long)|uniprotkb:Elf2(gene name synonym)|uniprotkb:Epl5(gene name synonym)|uniprotkb:Eplg5(gene name synonym)|uniprotkb:Htkl(gene name synonym)|uniprotkb:Lerk5(gene name synonym)|uniprotkb:Efnb2(gene name)|psi-mi:Efnb2(display_short)|uniprotkb:EPH-related receptor tyrosine kinase ligand 5(gene name synonym)|uniprotkb:ELF-2(gene name synonym)|uniprotkb:HTK ligand(gene name synonym) psi-mi:nck2_mouse(display_long)|uniprotkb:Nck2(gene name)|psi-mi:Nck2(display_short)|uniprotkb:Grb4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym) psi-mi:"MI:0081"(peptide array) Su et al. (2004) pubmed:15096211|mint:MINT-6731623|doi:10.1111/j.1432-1033.2004.04078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7169192|mint:MINT-8038327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034241.2|ensembl:ENSMUSG00000001300(gene)|ensembl:ENSMUST00000001319(transcript)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52800|rcsb pdb:1IKO|rcsb pdb:1KGY|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|dip:DIP-29208N|mint:MINT-8038331(identity)|uniprotkb:P52800(original identifier) refseq:NP_035009.3|ensembl:ENSMUSG00000066877(gene)|ensembl:ENSMUST00000086421(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O55033|reactome:R-MMU-186763|reactome:R-MMU-373753|reactome:R-MMU-3928664|reactome:R-MMU-4420097|reactome:R-MMU-9013420|reactome:R-MMU-9013424|mint:MINT-8038328(identity)|uniprotkb:O55033(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/29 2014/10/16 rogid:P051BaTxVceRTs9h3ugIgtq/EGo10090 rogid:mFoknzNaD3XbNFCp57d5BUqEtAo10090 intact-crc:B5C4E0BFF39CBF51|rigid:YXj8rCg5TvdrkGcQcqeuNGN3VLs false binding-associated region:300-313(MINT-8038334)|phosphorylated residue:307-307(MINT-8038336) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)