#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15891	uniprotkb:P53974	intact:EBI-2036|uniprotkb:D6VR88|ensemblfungi:YCR088W	intact:EBI-9817|ensemblfungi:YNL020C|uniprotkb:D6W1F9	psi-mi:abp1_yeast(display_long)|uniprotkb:ABP1(gene name)|psi-mi:ABP1(display_short)|uniprotkb:YCR88W(orf name)|uniprotkb:YCR088W(locus name)	psi-mi:ark1_yeast(display_long)|uniprotkb:N2823(orf name)|uniprotkb:YNL020C(locus name)|uniprotkb:ARK1(gene name)|psi-mi:ARK1(display_short)	psi-mi:"MI:0051"(fluorescence technology)	Zarrinpar et al. (2003)	pubmed:14668868|mint:MINT-6742550	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7068196|mint:MINT-7721730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000684|refseq:NP_010012.1|dip:DIP-534N|mint:P15891|ensemblfungi:YCR088W(gene)|ensemblfungi:YCR088W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043332"(mating projection tip)|go:"GO:0044379"(protein localization to actin cortical patch)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR035718|interpro:IPR036028|rcsb pdb:1HQZ|rcsb pdb:1JO8|rcsb pdb:2K3B|rcsb pdb:2RPN|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-9013405|mint:MINT-7721731(identity)|uniprotkb:P15891(original identifier)	refseq:NP_014378.1|sgd:S000004965|ensemblfungi:YNL020C(gene)|ensemblfungi:YNL020C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2RPN|reactome:R-SCE-8856828|dip:DIP-4381N|mint:P53974|mint:MINT-7721737(identity)|uniprotkb:P53974(original identifier)	-	crc64:39523510704D94AA	crc64:139CA4CA1B6A181F	figure legend:F2|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/04/07	2014/10/16	rogid:GNPpMO8tuHFODmA3UzxSuTpdqZY559292	rogid:0Hk0FS0JZhF87+YeYCya2eAyH8M559292	intact-crc:2039DF44AC680E34|rigid:0sv8lL0ibr2WvKUB34ZIcYUfD9s	false	binding-associated region:535-592(MINT-7721734)	binding-associated region:605-620(MINT-7721740)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08018	uniprotkb:P08018	intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C	intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C	psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym)	psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Zarrinpar et al. (2003)	pubmed:14668868|mint:MINT-6742550	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7068225|mint:MINT-7721742	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N|mint:MINT-7721749(identity)|uniprotkb:P08018(original identifier)	refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N|mint:MINT-7721760(identity)|uniprotkb:P08018(original identifier)	-	crc64:9BC3435BDAFE8019	crc64:9BC3435BDAFE8019	figure legend:F2|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/04/07	2014/10/16	rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292	rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292	intact-crc:2D359FF32D39BECE|rigid:Ggx8tZbYSAt8MzKGTpAbD3XBwzw	false	binding-associated region:92-106(MINT-7721752)	binding-associated region:92-106(MINT-7721763)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08018	uniprotkb:P40073	intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C	intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C	psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym)	psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Zarrinpar et al. (2003)	pubmed:14668868|mint:MINT-6742550	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7068225|mint:MINT-7721742	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N|mint:MINT-7721749(identity)|uniprotkb:P08018(original identifier)	refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073|mint:MINT-7721743(identity)|uniprotkb:P40073(original identifier)	-	crc64:9BC3435BDAFE8019	crc64:E467A4D50AA3EDB6	figure legend:F2|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/04/07	2014/10/16	rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292	rogid:DPpJB36kZxbFXugXajgs899epuY559292	intact-crc:2D359FF32D39BECE|rigid:Ggx8tZbYSAt8MzKGTpAbD3XBwzw	false	binding-associated region:92-106(MINT-7721752)	binding-associated region:303-360(MINT-7721746)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08018	uniprotkb:P40073	intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C	intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C	psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym)	psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Zarrinpar et al. (2003)	pubmed:14668868|mint:MINT-6742550	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7068225|mint:MINT-7721742	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N|mint:MINT-7721749(identity)|uniprotkb:P08018(original identifier)	refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073|mint:MINT-7721754(identity)|uniprotkb:P40073(original identifier)	-	crc64:9BC3435BDAFE8019	crc64:E467A4D50AA3EDB6	figure legend:F2|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/04/07	2014/10/16	rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292	rogid:DPpJB36kZxbFXugXajgs899epuY559292	intact-crc:2D359FF32D39BECE|rigid:Ggx8tZbYSAt8MzKGTpAbD3XBwzw	false	binding-associated region:92-106(MINT-7721752)	binding-associated region:303-360(MINT-7721757)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)