#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8N668	uniprotkb:P51172	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-2547114|ensembl:ENSP00000368411|uniprotkb:A9Z1X6|uniprotkb:Q08AQ3|uniprotkb:Q5T7L3|uniprotkb:Q8NA24|uniprotkb:B1PS44|uniprotkb:Q09HT0|uniprotkb:A6NNF7|uniprotkb:B3KSD7	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:scnnd_human(display_long)|uniprotkb:SCNN1D(gene name)|psi-mi:SCNN1D(display_short)|uniprotkb:DNACH(gene name synonym)|uniprotkb:"Epithelial Na(+) channel subunit delta"(gene name synonym)|uniprotkb:SCNED(gene name synonym)|uniprotkb:Nonvoltage-gated sodium channel 1 subunit delta(gene name synonym)|uniprotkb:Delta-NaCH(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Biasio et al. (2004)	pubmed:14645214|imex:IM-20436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2547150|imex:IM-20436-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSG00000162572(gene)|ensembl:ENST00000379116(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|reactome:R-HSA-2672351|refseq:XP_011540227.1|refseq:XP_011540234.1|refseq:XP_011540235.1|refseq:NP_001123885.2	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/01/25	2019/01/23	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:ci1OfIrlsgtIVnxmbQNMYg0DOq49606	intact-crc:00E0F7D05549621D|rigid:QNHLzIzXTCmmVjlJ8rl5sa5gcHo	false	-	sufficient binding region:726-802	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51172	uniprotkb:Q8N668	intact:EBI-2547114|ensembl:ENSP00000368411|uniprotkb:A9Z1X6|uniprotkb:Q08AQ3|uniprotkb:Q5T7L3|uniprotkb:Q8NA24|uniprotkb:B1PS44|uniprotkb:Q09HT0|uniprotkb:A6NNF7|uniprotkb:B3KSD7	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:scnnd_human(display_long)|uniprotkb:SCNN1D(gene name)|psi-mi:SCNN1D(display_short)|uniprotkb:DNACH(gene name synonym)|uniprotkb:"Epithelial Na(+) channel subunit delta"(gene name synonym)|uniprotkb:SCNED(gene name synonym)|uniprotkb:Nonvoltage-gated sodium channel 1 subunit delta(gene name synonym)|uniprotkb:Delta-NaCH(gene name synonym)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Biasio et al. (2004)	pubmed:14645214|imex:IM-20436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2547161|imex:IM-20436-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162572(gene)|ensembl:ENST00000379116(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|reactome:R-HSA-2672351|refseq:XP_011540227.1|refseq:XP_011540234.1|refseq:XP_011540235.1|refseq:NP_001123885.2	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Figs. 1A, 2 and 6|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/01/25	2019/01/23	rogid:ci1OfIrlsgtIVnxmbQNMYg0DOq49606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	intact-crc:C721182BC5FBA1D7|rigid:QNHLzIzXTCmmVjlJ8rl5sa5gcHo	false	necessary binding region:756-779|flag tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51168	uniprotkb:Q8N668	intact:EBI-2547187|ensembl:ENSP00000345751|uniprotkb:C5HTZ2|uniprotkb:O60891|uniprotkb:Q96KG2|uniprotkb:Q9UJ32|uniprotkb:Q9UMU5	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:scnnb_human(display_long)|uniprotkb:SCNN1B(gene name)|psi-mi:SCNN1B(display_short)|uniprotkb:"Epithelial Na(+) channel subunit beta"(gene name synonym)|uniprotkb:SCNEB(gene name synonym)|uniprotkb:Nonvoltage-gated sodium channel 1 subunit beta(gene name synonym)|uniprotkb:Beta-NaCH(gene name synonym)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Biasio et al. (2004)	pubmed:14645214|imex:IM-20436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2547224|imex:IM-20436-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168447(gene)|ensembl:ENST00000343070(transcript)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007588"(excretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032094"(response to food)|go:"GO:0032341"(aldosterone metabolic process)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042493"|go:"GO:0050699"(WW domain binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070254"(mucus secretion)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0097274"(urea homeostasis)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6BQN|rcsb pdb:6WTH|reactome:R-HSA-2672351|refseq:NP_000327.2	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 6A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/01/25	2014/10/16	rogid:0V4pnxmI6KdZ8GaIuuLdAbrfamQ9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	intact-crc:69C3D270383BD800|rigid:KsyCIJ3gdzvOdqzjn3jq/MMRS50	false	ha tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51170	uniprotkb:Q8N668	intact:EBI-2547354|ensembl:ENSP00000300061|uniprotkb:P78437|uniprotkb:Q6PCC2|uniprotkb:Q93023|uniprotkb:Q93024|uniprotkb:Q93025|uniprotkb:Q93026|uniprotkb:Q93027|uniprotkb:Q96TD2	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:scnng_human(display_long)|uniprotkb:SCNN1G(gene name)|psi-mi:SCNN1G(display_short)|uniprotkb:"Epithelial Na(+) channel subunit gamma"(gene name synonym)|uniprotkb:SCNEG(gene name synonym)|uniprotkb:Nonvoltage-gated sodium channel 1 subunit gamma(gene name synonym)|uniprotkb:Gamma-NaCH(gene name synonym)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Biasio et al. (2004)	pubmed:14645214|imex:IM-20436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2547348|imex:IM-20436-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166828(gene)|ensembl:ENST00000300061(transcript)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007588"(excretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0005216"(ion channel activity)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0050699"(WW domain binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6BQN|rcsb pdb:6WTH|reactome:R-HSA-2672351|refseq:NP_001030.2	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 6A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/01/25	2014/10/16	rogid:y3n1CDg1c7oj3ugrx9Kur21BmNk9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	intact-crc:9CD26565E9EC27DE|rigid:AYY7NxidEQ21+5PQM0gKyQdsaGI	false	ha tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8N668	uniprotkb:P51172	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-2547114|ensembl:ENSP00000368411|uniprotkb:A9Z1X6|uniprotkb:Q08AQ3|uniprotkb:Q5T7L3|uniprotkb:Q8NA24|uniprotkb:B1PS44|uniprotkb:Q09HT0|uniprotkb:A6NNF7|uniprotkb:B3KSD7	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:scnnd_human(display_long)|uniprotkb:SCNN1D(gene name)|psi-mi:SCNN1D(display_short)|uniprotkb:DNACH(gene name synonym)|uniprotkb:"Epithelial Na(+) channel subunit delta"(gene name synonym)|uniprotkb:SCNED(gene name synonym)|uniprotkb:Nonvoltage-gated sodium channel 1 subunit delta(gene name synonym)|uniprotkb:Delta-NaCH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Biasio et al. (2004)	pubmed:14645214|imex:IM-20436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2547176|imex:IM-20436-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSG00000162572(gene)|ensembl:ENST00000379116(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|reactome:R-HSA-2672351|refseq:XP_011540227.1|refseq:XP_011540234.1|refseq:XP_011540235.1|refseq:NP_001123885.2	-	-	-	figure legend:Figs. 1A and 2|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2010/01/25	2019/01/23	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:ci1OfIrlsgtIVnxmbQNMYg0DOq49606	intact-crc:C44E62B1C085E37D|rigid:QNHLzIzXTCmmVjlJ8rl5sa5gcHo	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)