#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01127	uniprotkb:P01127	intact:EBI-1554925|uniprotkb:P78431|uniprotkb:Q9UF23|uniprotkb:G3XAG8|uniprotkb:Q15354|uniprotkb:Q6FHE7|ensembl:ENSP00000330382	intact:EBI-1554925|uniprotkb:P78431|uniprotkb:Q9UF23|uniprotkb:G3XAG8|uniprotkb:Q15354|uniprotkb:Q6FHE7|ensembl:ENSP00000330382	psi-mi:pdgfb_human(display_long)|uniprotkb:Platelet-derived growth factor B chain(gene name synonym)|uniprotkb:Platelet-derived growth factor beta polypeptide(gene name synonym)|uniprotkb:PDGF-2(gene name synonym)|uniprotkb:Proto-oncogene c-Sis(gene name synonym)|uniprotkb:PDGFB(gene name)|psi-mi:PDGFB(display_short)|uniprotkb:PDGF2(gene name synonym)|uniprotkb:SIS(gene name synonym)	psi-mi:pdgfb_human(display_long)|uniprotkb:Platelet-derived growth factor B chain(gene name synonym)|uniprotkb:Platelet-derived growth factor beta polypeptide(gene name synonym)|uniprotkb:PDGF-2(gene name synonym)|uniprotkb:Proto-oncogene c-Sis(gene name synonym)|uniprotkb:PDGFB(gene name)|psi-mi:PDGFB(display_short)|uniprotkb:PDGF2(gene name synonym)|uniprotkb:SIS(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Oefner et al. (1992)	pubmed:1396586|imex:IM-18953	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2881377|wwpdb:1PDG|imex:IM-18953-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002599.1|refseq:NP_148937.1|dip:DIP-5737N|ensembl:ENSG00000100311(gene)|ensembl:ENST00000331163(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035793"(positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071506"(cellular response to mycophenolic acid)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072255"(metanephric glomerular mesangial cell development)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905176"(positive regulation of vascular associated smooth muscle cell dedifferentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000591"(positive regulation of metanephric mesenchymal cell migration)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR006782(Platelet-derived growth factor, N-terminal)|interpro:IPR015583(Platelet-Derived Growth Factor B Chain)|interpro:IPR023581|interpro:IPR029034|rcsb pdb:1PDG|rcsb pdb:3MJG|rcsb pdb:4HQU|rcsb pdb:4HQX|rcsb pdb:4QCI|rcsb pdb:6T9E|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-186763|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-3000171|reactome:R-HSA-5673001|reactome:R-HSA-6811558	refseq:NP_002599.1|refseq:NP_148937.1|dip:DIP-5737N|ensembl:ENSG00000100311(gene)|ensembl:ENST00000331163(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035793"(positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071506"(cellular response to mycophenolic acid)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072255"(metanephric glomerular mesangial cell development)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905176"(positive regulation of vascular associated smooth muscle cell dedifferentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000591"(positive regulation of metanephric mesenchymal cell migration)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR006782(Platelet-derived growth factor, N-terminal)|interpro:IPR015583(Platelet-Derived Growth Factor B Chain)|interpro:IPR023581|interpro:IPR029034|rcsb pdb:1PDG|rcsb pdb:3MJG|rcsb pdb:4HQU|rcsb pdb:4HQX|rcsb pdb:4QCI|rcsb pdb:6T9E|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-186763|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-3000171|reactome:R-HSA-5673001|reactome:R-HSA-6811558	-	-	-	3d-resolution:3.0 A|3d-r-factors:"Observed:20.9%"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/07/05	2014/10/16	rogid:6zBbnXOTaM6thsuAbXfQoHHZ/EA9606	rogid:6zBbnXOTaM6thsuAbXfQoHHZ/EA9606	intact-crc:DED1AC4C233180FD|rigid:07Tdie87jdXu+wzMFbJt6u/QE18	false	sufficient binding region:82-190(IPR000072)	sufficient binding region:82-190(IPR000072)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)