#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UIB8	uniprotkb:O14796	intact:EBI-6691679|ensembl:ENSP00000312367|uniprotkb:B2R8T1|uniprotkb:B7Z3R8|uniprotkb:O15430|uniprotkb:O95266|uniprotkb:O95660|uniprotkb:Q5H9R1|uniprotkb:Q6FHA8|uniprotkb:Q8WLP1|uniprotkb:Q8WWI8|uniprotkb:Q9UF04|uniprotkb:Q9UIB6|uniprotkb:Q9UIB7|uniprotkb:Q9UIT7	intact:EBI-3923013|uniprotkb:Q8NI18|uniprotkb:B2RBN6|uniprotkb:Q969K9|uniprotkb:Q5T0L1|ensembl:ENSP00000356906	psi-mi:slaf5_human(display_long)|uniprotkb:CD84(gene name)|psi-mi:CD84(display_short)|uniprotkb:SLAMF5(gene name synonym)|uniprotkb:Cell surface antigen MAX.3(gene name synonym)|uniprotkb:Hly9-beta(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD84(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 5(gene name synonym)	psi-mi:sh21b_human(display_long)|uniprotkb:SH2D1B(gene name)|psi-mi:SH2D1B(display_short)|uniprotkb:EAT2(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tangye et al. (2003)	pubmed:12928397|mint:MINT-6731566	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6997033|mint:MINT-8026176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001317671.1|ensembl:ENSG00000066294(gene)|ensembl:ENST00000311224(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006952"(defense response)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0032685"(negative regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2PKD|reactome:R-HSA-202733|interpro:IPR003599(Immunoglobulin subtype)|refseq:NP_001171808.1|refseq:NP_001171810.1|refseq:NP_001171811.1|refseq:NP_003865.1|ensembl:ENSG00000066294|ensembl:ENSG00000066294|ensembl:ENSG00000066294|dip:DIP-60957N|mint:MINT-8026180(identity)|uniprotkb:Q9UIB8(original identifier)	refseq:NP_444512.2|ensembl:ENSG00000198574(gene)|ensembl:ENST00000367929(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0005829"(cytosol)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|rcsb pdb:5KAZ|reactome:R-HSA-198933|mint:MINT-8026177(identity)|uniprotkb:O14796(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:i4o7JgNmjLKaueK1cKJJllrEERg9606	rogid:sbsE/jcSEsUrt8tK/EDz33pQqNQ9606	intact-crc:48C473E7287349E0|rigid:fh2gGIJ+j07P/DUNeGg13DC+PqE	false	binding-associated region:272-285(MINT-8026183)|phosphorylated residue:279-279(MINT-8026185)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UIB8	uniprotkb:O14796	intact:EBI-6691679|ensembl:ENSP00000312367|uniprotkb:B2R8T1|uniprotkb:B7Z3R8|uniprotkb:O15430|uniprotkb:O95266|uniprotkb:O95660|uniprotkb:Q5H9R1|uniprotkb:Q6FHA8|uniprotkb:Q8WLP1|uniprotkb:Q8WWI8|uniprotkb:Q9UF04|uniprotkb:Q9UIB6|uniprotkb:Q9UIB7|uniprotkb:Q9UIT7	intact:EBI-3923013|uniprotkb:Q8NI18|uniprotkb:B2RBN6|uniprotkb:Q969K9|uniprotkb:Q5T0L1|ensembl:ENSP00000356906	psi-mi:slaf5_human(display_long)|uniprotkb:CD84(gene name)|psi-mi:CD84(display_short)|uniprotkb:SLAMF5(gene name synonym)|uniprotkb:Cell surface antigen MAX.3(gene name synonym)|uniprotkb:Hly9-beta(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD84(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 5(gene name synonym)	psi-mi:sh21b_human(display_long)|uniprotkb:SH2D1B(gene name)|psi-mi:SH2D1B(display_short)|uniprotkb:EAT2(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tangye et al. (2003)	pubmed:12928397|mint:MINT-6731566	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6997069|mint:MINT-8028807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001317671.1|ensembl:ENSG00000066294(gene)|ensembl:ENST00000311224(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006952"(defense response)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0032685"(negative regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2PKD|reactome:R-HSA-202733|interpro:IPR003599(Immunoglobulin subtype)|refseq:NP_001171808.1|refseq:NP_001171810.1|refseq:NP_001171811.1|refseq:NP_003865.1|ensembl:ENSG00000066294|ensembl:ENSG00000066294|ensembl:ENSG00000066294|dip:DIP-60957N|mint:MINT-8028811(identity)|uniprotkb:Q9UIB8(original identifier)	refseq:NP_444512.2|ensembl:ENSG00000198574(gene)|ensembl:ENST00000367929(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0005829"(cytosol)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|rcsb pdb:5KAZ|reactome:R-HSA-198933|mint:MINT-8028808(identity)|uniprotkb:O14796(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:i4o7JgNmjLKaueK1cKJJllrEERg9606	rogid:sbsE/jcSEsUrt8tK/EDz33pQqNQ9606	intact-crc:504490500EBB49E3|rigid:fh2gGIJ+j07P/DUNeGg13DC+PqE	false	binding-associated region:309-322(MINT-8028814)|phosphorylated residue:316-316(MINT-8028816)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60880	uniprotkb:Q9UIB8	intact:EBI-6983382|ensembl:ENSP00000360181|uniprotkb:O95386|uniprotkb:Q6FGS6|uniprotkb:O95385|intact:MINT-113697|uniprotkb:A8MSW0|uniprotkb:O95384|uniprotkb:O95383|uniprotkb:Q9UNR0	intact:EBI-6691679|ensembl:ENSP00000312367|uniprotkb:B2R8T1|uniprotkb:B7Z3R8|uniprotkb:O15430|uniprotkb:O95266|uniprotkb:O95660|uniprotkb:Q5H9R1|uniprotkb:Q6FHA8|uniprotkb:Q8WLP1|uniprotkb:Q8WWI8|uniprotkb:Q9UF04|uniprotkb:Q9UIB6|uniprotkb:Q9UIB7|uniprotkb:Q9UIT7	psi-mi:sh21a_human(display_long)|uniprotkb:SH2D1A(gene name)|psi-mi:SH2D1A(display_short)|uniprotkb:DSHP(gene name synonym)|uniprotkb:SAP(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule-associated protein(gene name synonym)|uniprotkb:T-cell signal transduction molecule SAP(gene name synonym)|uniprotkb:Duncan disease SH2-protein(gene name synonym)	psi-mi:slaf5_human(display_long)|uniprotkb:CD84(gene name)|psi-mi:CD84(display_short)|uniprotkb:SLAMF5(gene name synonym)|uniprotkb:Cell surface antigen MAX.3(gene name synonym)|uniprotkb:Hly9-beta(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD84(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 5(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tangye et al. (2003)	pubmed:12928397|mint:MINT-6731566	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6997051|mint:MINT-8026187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1D4W|rcsb pdb:1KA6|rcsb pdb:1KA7|rcsb pdb:1M27|reactome:R-HSA-198933|ensembl:ENSG00000183918(gene)|ensembl:ENST00000371139(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006959"(humoral immune response)|go:"GO:0006968"(cellular defense response)|rcsb pdb:1D4T|go:"GO:0007267"(cell-cell signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR017289(SH2 protein 1A)|interpro:IPR035876|interpro:IPR036860|rcsb pdb:1D1Z|refseq:NP_001108409.1|refseq:NP_002342.1|dip:DIP-40768N|mint:MINT-8026188(identity)|uniprotkb:O60880(original identifier)	refseq:NP_001317671.1|ensembl:ENSG00000066294(gene)|ensembl:ENST00000311224(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006952"(defense response)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0032685"(negative regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2PKD|reactome:R-HSA-202733|interpro:IPR003599(Immunoglobulin subtype)|refseq:NP_001171808.1|refseq:NP_001171810.1|refseq:NP_001171811.1|refseq:NP_003865.1|ensembl:ENSG00000066294|ensembl:ENSG00000066294|ensembl:ENSG00000066294|dip:DIP-60957N|mint:MINT-8026191(identity)|uniprotkb:Q9UIB8(original identifier)	-	comment:mint|function:Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the slam cytoplasmic region|function:"Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1) [MIM:308240]; also known as X-linked lymphoproliferative disease (XLPD) or Duncan disease. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:tJL+FA6RUPeEknwUp85WT2p0+/c9606	rogid:i4o7JgNmjLKaueK1cKJJllrEERg9606	intact-crc:1575EDAEA0E71C5C|rigid:ou/rmNDwqUWcYGX9bC4cJR2uqfw	false	-	phosphorylated residue:279-279(MINT-8026196)|binding-associated region:272-285(MINT-8026194)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)