#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52630 uniprotkb:P17181 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 intact:EBI-1547250|uniprotkb:Q53GW9|uniprotkb:Q53H11|uniprotkb:Q8WTZ2|uniprotkb:Q6PKD7|uniprotkb:Q7M4L2|uniprotkb:B4DNT3|uniprotkb:D3DSF0|uniprotkb:B2R6L9|ensembl:ENSP00000270139 psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:inar1_human(display_long)|uniprotkb:IFNAR1(gene name)|psi-mi:IFNAR1(display_short)|uniprotkb:IFNAR(gene name synonym)|uniprotkb:Type I interferon receptor 1(gene name synonym)|uniprotkb:Cytokine receptor family 2 member 1(gene name synonym)|uniprotkb:Cytokine receptor class-II member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Saleh et al. (2002) pubmed:12220192|mint:MINT-6731487 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8524332|mint:MINT-8029488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|mint:MINT-8029489(identity)|uniprotkb:P52630(original identifier) refseq:NP_000620.2|refseq:XP_005261021.1|dip:DIP-57N|ensembl:ENSG00000142166(gene)|ensembl:ENST00000270139(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004905"(type I interferon receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019962"(type I interferon binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR016669(Interferon-alpha/beta receptor 1)|interpro:IPR036116|rcsb pdb:3S98|rcsb pdb:3SE3|rcsb pdb:3SE4|rcsb pdb:4PO6|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|mint:MINT-8029492(identity)|uniprotkb:P17181(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/28 2014/10/16 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 rogid:DuOuIr85nya6Ti494f43fftNRyo9606 intact-crc:86AAC7B9BC57F450|rigid:DPZwBfK5kJ5PaQEd53G+u1m/0lU false - phosphorylated residue:466-466(MINT-8029497)|binding-associated region:459-472(MINT-8029495) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17181 uniprotkb:P52630 intact:EBI-1547250|uniprotkb:Q53GW9|uniprotkb:Q53H11|uniprotkb:Q8WTZ2|uniprotkb:Q6PKD7|uniprotkb:Q7M4L2|uniprotkb:B4DNT3|uniprotkb:D3DSF0|uniprotkb:B2R6L9|ensembl:ENSP00000270139 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:inar1_human(display_long)|uniprotkb:IFNAR1(gene name)|psi-mi:IFNAR1(display_short)|uniprotkb:IFNAR(gene name synonym)|uniprotkb:Type I interferon receptor 1(gene name synonym)|uniprotkb:Cytokine receptor family 2 member 1(gene name synonym)|uniprotkb:Cytokine receptor class-II member 1(gene name synonym) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Saleh et al. (2002) pubmed:12220192|mint:MINT-6731487 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8524362|mint:MINT-8029503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000620.2|refseq:XP_005261021.1|dip:DIP-57N|ensembl:ENSG00000142166(gene)|ensembl:ENST00000270139(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004905"(type I interferon receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019962"(type I interferon binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR016669(Interferon-alpha/beta receptor 1)|interpro:IPR036116|rcsb pdb:3S98|rcsb pdb:3SE3|rcsb pdb:3SE4|rcsb pdb:4PO6|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|mint:MINT-8029507(identity)|uniprotkb:P17181(original identifier) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|mint:MINT-8029504(identity)|uniprotkb:P52630(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/28 2014/10/16 rogid:DuOuIr85nya6Ti494f43fftNRyo9606 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:7E558CC813A90150|rigid:DPZwBfK5kJ5PaQEd53G+u1m/0lU false phosphorylated residue:466-466(MINT-8029512)|binding-associated region:459-472(MINT-8029510) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)