#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06101 uniprotkb:P00546 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mort-Bontemps-Soret et al. (2002) pubmed:12111552|imex:IM-20465 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2607677|imex:IM-20465-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 - crc64:0DF0C923158A2526 crc64:57A7A2B97A90DC6C figure legend:Table 4, Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/02 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 intact-crc:629009FF939DD629|rigid:F3NdeKSNLN+Lykv/7T1+Pl3jppg false sufficient binding region:286-506 sufficient binding region:1-116 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06101 uniprotkb:P43568 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-3953|uniprotkb:D6VTK1|ensemblfungi:YFL029C psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:cak1_yeast(display_long)|uniprotkb:CAK1(gene name)|psi-mi:CAK1(display_short)|uniprotkb:CIV1(gene name synonym)|uniprotkb:CDK-activating kinase(gene name synonym)|uniprotkb:YFL029C(locus name) psi-mi:"MI:0018"(two hybrid) Mort-Bontemps-Soret et al. (2002) pubmed:12111552|imex:IM-20465 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2640977|imex:IM-20465-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 refseq:NP_116624.1|sgd:S000001865|dip:DIP-1637N|mint:P43568|ensemblfungi:YFL029C(gene)|ensemblfungi:YFL029C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-3214858|reactome:R-SCE-69231|reactome:R-SCE-75815 - crc64:0DF0C923158A2526 crc64:852AFD1E95B90C42 figure legend:Table 4, Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/02 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:e7WGRhYEDHIiE7iyS/2E/GvlA/0559292 intact-crc:DA882A9411420398|rigid:aZa92wybVzMOFyEkv+q0GDN5MU8 false - sufficient binding region:1-146 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06101 uniprotkb:P54199 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mort-Bontemps-Soret et al. (2002) pubmed:12111552|imex:IM-20465 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2640983|imex:IM-20465-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N - crc64:0DF0C923158A2526 - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/02 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 intact-crc:CAF5A9BC74F2A1F7|rigid:jVJ9lLofsUAQA1c3ngLa2HD4tDU false - sufficient binding region:433-543 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06101 uniprotkb:P06243 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-4451|uniprotkb:D6VRX3|ensemblfungi:YDL017W psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:cdc7_yeast(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:OAF2(gene name synonym)|uniprotkb:YDL017W(locus name)|uniprotkb:D2855(orf name) psi-mi:"MI:0018"(two hybrid) Mort-Bontemps-Soret et al. (2002) pubmed:12111552|imex:IM-20465 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2640989|imex:IM-20465-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 sgd:S000002175|mint:P06243|refseq:NP_010267.3|dip:DIP-1235N|ensemblfungi:YDL017W(gene)|ensemblfungi:YDL017W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060903"(positive regulation of meiosis I)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|go:"GO:1904968"(positive regulation of monopolar spindle attachment to meiosis I kinetochore)|go:"GO:1905263"(positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5T2S|reactome:R-SCE-68962 - crc64:0DF0C923158A2526 crc64:B74BA9144D0EC39F figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/02 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:DDbpXCtfnaBaEZTzMGOfNGNmfrk559292 intact-crc:E483CEACEED93D7C|rigid:iw3MVfDnGTK+W5S8+sVVZhYybO0 false - sufficient binding region:26-143 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06101 uniprotkb:P23561 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Mort-Bontemps-Soret et al. (2002) pubmed:12111552|imex:IM-20465 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2640995|imex:IM-20465-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:0DF0C923158A2526 crc64:E9E0DF27114EEEEF figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/02 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:CD3335A7A786714B|rigid:i9P+B/ADGYUJvvWZ8SxfLdPyt2Q false - sufficient binding region:409-559 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)